Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation
The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
JB Jeeva [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Rechteinformationen: |
Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. |
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| Schlagwörter: |
Photons backscattering and transillumination Image Processing, Computer-Assisted - methods |
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| Übergeordnetes Werk: |
Enthalten in: Computers in biology and medicine - New York, NY [u.a.] : Pergamon Press, 1970, 60(2015), Seite 92-99 |
|---|---|
| Übergeordnetes Werk: |
volume:60 ; year:2015 ; pages:92-99 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.compbiomed.2015.02.014 |
|---|
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| 245 | 1 | 0 | |a Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation |
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| 520 | |a The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. | ||
| 540 | |a Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. | ||
| 650 | 4 | |a Monte Carlo simulation | |
| 650 | 4 | |a Phantoms | |
| 650 | 4 | |a Photons backscattering and transillumination | |
| 650 | 4 | |a Inhomogeneities/tumor | |
| 650 | 4 | |a Optical properties | |
| 650 | 4 | |a Spleen | |
| 650 | 4 | |a Tomography | |
| 650 | 4 | |a Ultrasonic imaging | |
| 650 | 4 | |a Cancer | |
| 650 | 4 | |a Adipose Tissue - pathology | |
| 650 | 4 | |a Optical Imaging - methods | |
| 650 | 4 | |a Image Processing, Computer-Assisted - methods | |
| 650 | 4 | |a Myocardium - pathology | |
| 650 | 4 | |a Neoplasms - diagnosis | |
| 650 | 4 | |a Diagnostic Imaging - methods | |
| 650 | 4 | |a Neoplasms - pathology | |
| 650 | 4 | |a Optics and Photonics - methods | |
| 650 | 4 | |a Spleen - pathology | |
| 700 | 0 | |a Megha Singh |4 oth | |
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10.1016/j.compbiomed.2015.02.014 doi PQ20160617 (DE-627)OLC1962382184 (DE-599)GBVOLC1962382184 (PRQ)c2778-abecf07f95f5cb15d1a82f1bbef2b2a1a655c30a10e7d1dda655ac6a1d7413fe0 (KEY)0003445220150000060000000092reconstructionofopticalscannedimagesofinhomogeneit DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl JB Jeeva verfasserin aut Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology Megha Singh oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 60(2015), Seite 92-99 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:60 year:2015 pages:92-99 http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 60 2015 92-99 |
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10.1016/j.compbiomed.2015.02.014 doi PQ20160617 (DE-627)OLC1962382184 (DE-599)GBVOLC1962382184 (PRQ)c2778-abecf07f95f5cb15d1a82f1bbef2b2a1a655c30a10e7d1dda655ac6a1d7413fe0 (KEY)0003445220150000060000000092reconstructionofopticalscannedimagesofinhomogeneit DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl JB Jeeva verfasserin aut Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology Megha Singh oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 60(2015), Seite 92-99 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:60 year:2015 pages:92-99 http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 60 2015 92-99 |
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10.1016/j.compbiomed.2015.02.014 doi PQ20160617 (DE-627)OLC1962382184 (DE-599)GBVOLC1962382184 (PRQ)c2778-abecf07f95f5cb15d1a82f1bbef2b2a1a655c30a10e7d1dda655ac6a1d7413fe0 (KEY)0003445220150000060000000092reconstructionofopticalscannedimagesofinhomogeneit DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl JB Jeeva verfasserin aut Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology Megha Singh oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 60(2015), Seite 92-99 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:60 year:2015 pages:92-99 http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 60 2015 92-99 |
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10.1016/j.compbiomed.2015.02.014 doi PQ20160617 (DE-627)OLC1962382184 (DE-599)GBVOLC1962382184 (PRQ)c2778-abecf07f95f5cb15d1a82f1bbef2b2a1a655c30a10e7d1dda655ac6a1d7413fe0 (KEY)0003445220150000060000000092reconstructionofopticalscannedimagesofinhomogeneit DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl JB Jeeva verfasserin aut Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology Megha Singh oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 60(2015), Seite 92-99 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:60 year:2015 pages:92-99 http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 60 2015 92-99 |
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10.1016/j.compbiomed.2015.02.014 doi PQ20160617 (DE-627)OLC1962382184 (DE-599)GBVOLC1962382184 (PRQ)c2778-abecf07f95f5cb15d1a82f1bbef2b2a1a655c30a10e7d1dda655ac6a1d7413fe0 (KEY)0003445220150000060000000092reconstructionofopticalscannedimagesofinhomogeneit DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl JB Jeeva verfasserin aut Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology Megha Singh oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 60(2015), Seite 92-99 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:60 year:2015 pages:92-99 http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 60 2015 92-99 |
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610 570 DNB 44.00 bkl 42.00 bkl Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation Monte Carlo simulation Phantoms Photons backscattering and transillumination Inhomogeneities/tumor Optical properties Spleen Tomography Ultrasonic imaging Cancer Adipose Tissue - pathology Optical Imaging - methods Image Processing, Computer-Assisted - methods Myocardium - pathology Neoplasms - diagnosis Diagnostic Imaging - methods Neoplasms - pathology Optics and Photonics - methods Spleen - pathology |
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ddc 610 bkl 44.00 bkl 42.00 misc Monte Carlo simulation misc Phantoms misc Photons backscattering and transillumination misc Inhomogeneities/tumor misc Optical properties misc Spleen misc Tomography misc Ultrasonic imaging misc Cancer misc Adipose Tissue - pathology misc Optical Imaging - methods misc Image Processing, Computer-Assisted - methods misc Myocardium - pathology misc Neoplasms - diagnosis misc Diagnostic Imaging - methods misc Neoplasms - pathology misc Optics and Photonics - methods misc Spleen - pathology |
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Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation |
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Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation |
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reconstruction of optical scanned images of inhomogeneities in biological tissues by monte carlo simulation |
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Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation |
| abstract |
The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. |
| abstractGer |
The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. |
| abstract_unstemmed |
The optical imaging of inhomogeneities located in phantoms of biological tissues, prepared from goat's isolated heart as control tissue and embedded with spleen and adipose tissues representing tumors, by Monte Carlo simulation, is carried out. The proposed scanning probe consists of nine units. Each unit is equipped with one photon injection port and three ports arranged in a straight line to collect backscattered photons emerging from various depths, and one port, placed coaxially to the source on the opposite side of the phantom, to collect the transmitted component. At each position of the grid, superposed on the tissue phantom, photons are introduced through source port into the phantoms and backscattered and transmitted photons are collected by respective ports. Based on the data collected from the entire grid surface the respective gray-level images are reconstructed. The inhomogeneity located at certain depth (2, 4, 6mm) is visualized in three images formed by the backscattered data collected by three ports. Increase or decrease in normalized backscattered intensity (NBI) observed in their scans corresponds to that of high scattering (adipose) or absorbing (spleen) inhomogeneity compared to that of control tissue and also their location as determined by NBI variation as received at various ports. The images constructed from the transmitted data are associated with decrease in intensity. The scans of these images through their centers show that normalized transmitted intensity (NTI) attains its maximum value when the inhomogeneities are at depth 6mm. These scans are of higher amplitude for spleen compared to that of adipose tissues. Thus the data received by backscattering and transmission complement each other in identifying the location and type of inhomogeneities. |
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Reconstruction of optical scanned images of inhomogeneities in biological tissues by Monte Carlo simulation |
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http://dx.doi.org/10.1016/j.compbiomed.2015.02.014 http://www.ncbi.nlm.nih.gov/pubmed/25770705 http://search.proquest.com/docview/1672295109 |
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