Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects

Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three ty...
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Autor*in:	Alireza Sharifi [verfasserIn] Hamid Niazmand

Format:	Artikel
Sprache:	Englisch

Erschienen:	2015

Rechteinformationen:	Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved.

Schlagwörter:	Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer

Übergeordnetes Werk:	Enthalten in: Computers in biology and medicine - New York, NY [u.a.] : Pergamon Press, 1970, 65(2015), Seite 93-102
Übergeordnetes Werk:	volume:65 ; year:2015 ; pages:93-102

Links:	Volltext Link aufrufen Link aufrufen

DOI / URN:	10.1016/j.compbiomed.2015.08.002

Katalog-ID:	OLC1962384039

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520			\|a Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model.
540			\|a Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved.
650		4	\|a Non-Newtonian
650		4	\|a Internal carotid artery
650		4	\|a Blood hemodynamics
650		4	\|a Low-density lipoprotein
650		4	\|a Veins & arteries
650		4	\|a Velocity
650		4	\|a Studies
650		4	\|a Cholesterol
650		4	\|a Mass transfer
700	0		\|a Hamid Niazmand \|4 oth
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allfields	10.1016/j.compbiomed.2015.08.002 doi PQ20160617 (DE-627)OLC1962384039 (DE-599)GBVOLC1962384039 (PRQ)c2774-f3f6b8784fa5504249ca618eeffd9c1b89b85579554efeb8cb12ced7285e740a0 (KEY)0003445220150000065000000093analysisofflowandldlconcentrationpolarizationinsip DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl Alireza Sharifi verfasserin aut Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer Hamid Niazmand oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 65(2015), Seite 93-102 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:65 year:2015 pages:93-102 http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 Volltext http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 65 2015 93-102
spelling	10.1016/j.compbiomed.2015.08.002 doi PQ20160617 (DE-627)OLC1962384039 (DE-599)GBVOLC1962384039 (PRQ)c2774-f3f6b8784fa5504249ca618eeffd9c1b89b85579554efeb8cb12ced7285e740a0 (KEY)0003445220150000065000000093analysisofflowandldlconcentrationpolarizationinsip DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl Alireza Sharifi verfasserin aut Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer Hamid Niazmand oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 65(2015), Seite 93-102 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:65 year:2015 pages:93-102 http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 Volltext http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 65 2015 93-102
allfields_unstemmed	10.1016/j.compbiomed.2015.08.002 doi PQ20160617 (DE-627)OLC1962384039 (DE-599)GBVOLC1962384039 (PRQ)c2774-f3f6b8784fa5504249ca618eeffd9c1b89b85579554efeb8cb12ced7285e740a0 (KEY)0003445220150000065000000093analysisofflowandldlconcentrationpolarizationinsip DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl Alireza Sharifi verfasserin aut Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer Hamid Niazmand oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 65(2015), Seite 93-102 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:65 year:2015 pages:93-102 http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 Volltext http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 65 2015 93-102
allfieldsGer	10.1016/j.compbiomed.2015.08.002 doi PQ20160617 (DE-627)OLC1962384039 (DE-599)GBVOLC1962384039 (PRQ)c2774-f3f6b8784fa5504249ca618eeffd9c1b89b85579554efeb8cb12ced7285e740a0 (KEY)0003445220150000065000000093analysisofflowandldlconcentrationpolarizationinsip DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl Alireza Sharifi verfasserin aut Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer Hamid Niazmand oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 65(2015), Seite 93-102 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:65 year:2015 pages:93-102 http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 Volltext http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 65 2015 93-102
allfieldsSound	10.1016/j.compbiomed.2015.08.002 doi PQ20160617 (DE-627)OLC1962384039 (DE-599)GBVOLC1962384039 (PRQ)c2774-f3f6b8784fa5504249ca618eeffd9c1b89b85579554efeb8cb12ced7285e740a0 (KEY)0003445220150000065000000093analysisofflowandldlconcentrationpolarizationinsip DE-627 ger DE-627 rakwb eng 610 570 DNB 44.00 bkl 42.00 bkl Alireza Sharifi verfasserin aut Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model. Nutzungsrecht: Copyright © 2015 Elsevier Ltd. All rights reserved. Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer Hamid Niazmand oth Enthalten in Computers in biology and medicine New York, NY [u.a.] : Pergamon Press, 1970 65(2015), Seite 93-102 (DE-627)129312789 (DE-600)127557-4 (DE-576)014525828 0010-4825 nnns volume:65 year:2015 pages:93-102 http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 Volltext http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-MAT SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 44.00 AVZ 42.00 AVZ AR 65 2015 93-102
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source	Enthalten in Computers in biology and medicine 65(2015), Seite 93-102 volume:65 year:2015 pages:93-102
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topic_facet	Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer
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container_title	Computers in biology and medicine
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Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. 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author	Alireza Sharifi
spellingShingle	Alireza Sharifi ddc 610 bkl 44.00 bkl 42.00 misc Non-Newtonian misc Internal carotid artery misc Blood hemodynamics misc Low-density lipoprotein misc Veins & arteries misc Velocity misc Studies misc Cholesterol misc Mass transfer Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects
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topic_title	610 570 DNB 44.00 bkl 42.00 bkl Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects Non-Newtonian Internal carotid artery Blood hemodynamics Low-density lipoprotein Veins & arteries Velocity Studies Cholesterol Mass transfer
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title	Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects
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title_full	Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects
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title_sort	analysis of flow and ldl concentration polarization in siphon of internal carotid artery: non-newtonian effects
title_auth	Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects
abstract	Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model.
abstractGer	Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model.
abstract_unstemmed	Carotid siphon is known as one of the risky sites among the human intracranial arteries, which is prone to formation of atherosclerotic lesions. Indeed, scientists believe that accumulation of low density lipoprotein (LDL) inside the lumen is the major cause of atherosclerosis. To this aim, three types of internal carotid artery (ICA) siphon have been constructed to examine variations of hemodynamic parameters in different regions of the arteries. Providing real physiological conditions, blood considered as non-Newtonian fluid and real velocity and pressure waveforms have been employed as flow boundary conditions. Moreover, to have a better estimation of risky sites, the accumulation of LDL particles has been considered, which has been usually ignored in previous relevant studies. Governing equations have been discretized and solved via open source OpenFOAM software. A new solver has been built to meet essential parameters related to the flow and mass transfer phenomena. In contrast to the common belief regarding negligible effect of blood non-Newtonian behavior inside large arteries, current study suggests that the non-Newtonian blood behavior is notable, especially on the velocity field of the U-type model. In addition, it is concluded that neglecting non-Newtonian effects underestimates the LDL accumulation up to 3% in the U-type model at the inner side of both its bends. However, in the V and C type models, non-Newtonian effects become relatively small. Results also emphasize that the outer part of the second bend at the downstream is also at risk similar to the inner part of the carotid bends. Furthermore, from findings it can be implied that the risky sites strongly depend on the ICA shape since the extension of the risky sites are relatively larger for the V-type model, while the LDL concentrations are higher for the C-type model.
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title_short	Analysis of flow and LDL concentration polarization in siphon of internal carotid artery: Non-Newtonian effects
url	http://dx.doi.org/10.1016/j.compbiomed.2015.08.002 http://www.ncbi.nlm.nih.gov/pubmed/26313530 http://search.proquest.com/docview/1716966896
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up_date	2024-07-04T03:26:12.566Z
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