Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors
Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estima...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Borghi, Giacomo [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
monolithic Ca-codoped LSO:Ce crystals monolithic scintillator detector efficient fan-beam calibration procedure k-nearest neighbor position estimation |
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| Übergeordnetes Werk: |
Enthalten in: IEEE transactions on nuclear science - New York, NY : IEEE, 1963, 62(2015), 1, Seite 57-67 |
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| Übergeordnetes Werk: |
volume:62 ; year:2015 ; number:1 ; pages:57-67 |
| Links: |
|---|
| DOI / URN: |
10.1109/TNS.2014.2375557 |
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| 520 | |a Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. | ||
| 650 | 4 | |a medical imaging field | |
| 650 | 4 | |a fan beam | |
| 650 | 4 | |a fine grid | |
| 650 | 4 | |a reference position | |
| 650 | 4 | |a monolithic Ca-codoped LSO:Ce crystals | |
| 650 | 4 | |a calibration | |
| 650 | 4 | |a Estimation | |
| 650 | 4 | |a PET | |
| 650 | 4 | |a pencil-beam irradiation | |
| 650 | 4 | |a Crystals | |
| 650 | 4 | |a cerium | |
| 650 | 4 | |a scintillation counters | |
| 650 | 4 | |a Radiation effects | |
| 650 | 4 | |a monolithic scintillator detector | |
| 650 | 4 | |a reference events | |
| 650 | 4 | |a fan-beam method | |
| 650 | 4 | |a statistical method | |
| 650 | 4 | |a efficient fan-beam calibration procedure | |
| 650 | 4 | |a k-nearest neighbor position estimation | |
| 650 | 4 | |a gamma-ray detection | |
| 650 | 4 | |a Collimators | |
| 650 | 4 | |a monolithic scintillator detectors | |
| 650 | 4 | |a Detectors | |
| 650 | 4 | |a Spatial resolution | |
| 650 | 4 | |a digital photon counter arrays | |
| 650 | 4 | |a positron emission tomography | |
| 650 | 4 | |a tungsten slit collimator | |
| 650 | 4 | |a nearest neighbor method | |
| 650 | 4 | |a PET imaging | |
| 650 | 4 | |a Gamma rays | |
| 650 | 4 | |a Analysis | |
| 650 | 4 | |a Usage | |
| 700 | 1 | |a Tabacchini, Valerio |4 oth | |
| 700 | 1 | |a Seifert, Stefan |4 oth | |
| 700 | 1 | |a Schaart, Dennis R |4 oth | |
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| 856 | 4 | 1 | |u http://dx.doi.org/10.1109/TNS.2014.2375557 |3 Volltext |
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10.1109/TNS.2014.2375557 doi PQ20160617 (DE-627)OLC1966226276 (DE-599)GBVOLC1966226276 (PRQ)c1537-89aa2d1f4f25d72b18b1ae71214721a817ce5c8d96add93f40e5c7d089bc4ab20 (KEY)0054996720150000062000100057experimentalvalidationofanefficientfanbeamcalibrat DE-627 ger DE-627 rakwb eng 620 DNB Borghi, Giacomo verfasserin aut Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage Tabacchini, Valerio oth Seifert, Stefan oth Schaart, Dennis R oth Enthalten in IEEE transactions on nuclear science New York, NY : IEEE, 1963 62(2015), 1, Seite 57-67 (DE-627)129547352 (DE-600)218510-6 (DE-576)014998238 0018-9499 nnns volume:62 year:2015 number:1 pages:57-67 http://dx.doi.org/10.1109/TNS.2014.2375557 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7012118 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-PHA GBV_ILN_70 AR 62 2015 1 57-67 |
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10.1109/TNS.2014.2375557 doi PQ20160617 (DE-627)OLC1966226276 (DE-599)GBVOLC1966226276 (PRQ)c1537-89aa2d1f4f25d72b18b1ae71214721a817ce5c8d96add93f40e5c7d089bc4ab20 (KEY)0054996720150000062000100057experimentalvalidationofanefficientfanbeamcalibrat DE-627 ger DE-627 rakwb eng 620 DNB Borghi, Giacomo verfasserin aut Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage Tabacchini, Valerio oth Seifert, Stefan oth Schaart, Dennis R oth Enthalten in IEEE transactions on nuclear science New York, NY : IEEE, 1963 62(2015), 1, Seite 57-67 (DE-627)129547352 (DE-600)218510-6 (DE-576)014998238 0018-9499 nnns volume:62 year:2015 number:1 pages:57-67 http://dx.doi.org/10.1109/TNS.2014.2375557 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7012118 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-PHA GBV_ILN_70 AR 62 2015 1 57-67 |
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10.1109/TNS.2014.2375557 doi PQ20160617 (DE-627)OLC1966226276 (DE-599)GBVOLC1966226276 (PRQ)c1537-89aa2d1f4f25d72b18b1ae71214721a817ce5c8d96add93f40e5c7d089bc4ab20 (KEY)0054996720150000062000100057experimentalvalidationofanefficientfanbeamcalibrat DE-627 ger DE-627 rakwb eng 620 DNB Borghi, Giacomo verfasserin aut Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage Tabacchini, Valerio oth Seifert, Stefan oth Schaart, Dennis R oth Enthalten in IEEE transactions on nuclear science New York, NY : IEEE, 1963 62(2015), 1, Seite 57-67 (DE-627)129547352 (DE-600)218510-6 (DE-576)014998238 0018-9499 nnns volume:62 year:2015 number:1 pages:57-67 http://dx.doi.org/10.1109/TNS.2014.2375557 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7012118 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-PHA GBV_ILN_70 AR 62 2015 1 57-67 |
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10.1109/TNS.2014.2375557 doi PQ20160617 (DE-627)OLC1966226276 (DE-599)GBVOLC1966226276 (PRQ)c1537-89aa2d1f4f25d72b18b1ae71214721a817ce5c8d96add93f40e5c7d089bc4ab20 (KEY)0054996720150000062000100057experimentalvalidationofanefficientfanbeamcalibrat DE-627 ger DE-627 rakwb eng 620 DNB Borghi, Giacomo verfasserin aut Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage Tabacchini, Valerio oth Seifert, Stefan oth Schaart, Dennis R oth Enthalten in IEEE transactions on nuclear science New York, NY : IEEE, 1963 62(2015), 1, Seite 57-67 (DE-627)129547352 (DE-600)218510-6 (DE-576)014998238 0018-9499 nnns volume:62 year:2015 number:1 pages:57-67 http://dx.doi.org/10.1109/TNS.2014.2375557 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7012118 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-PHA GBV_ILN_70 AR 62 2015 1 57-67 |
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10.1109/TNS.2014.2375557 doi PQ20160617 (DE-627)OLC1966226276 (DE-599)GBVOLC1966226276 (PRQ)c1537-89aa2d1f4f25d72b18b1ae71214721a817ce5c8d96add93f40e5c7d089bc4ab20 (KEY)0054996720150000062000100057experimentalvalidationofanefficientfanbeamcalibrat DE-627 ger DE-627 rakwb eng 620 DNB Borghi, Giacomo verfasserin aut Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage Tabacchini, Valerio oth Seifert, Stefan oth Schaart, Dennis R oth Enthalten in IEEE transactions on nuclear science New York, NY : IEEE, 1963 62(2015), 1, Seite 57-67 (DE-627)129547352 (DE-600)218510-6 (DE-576)014998238 0018-9499 nnns volume:62 year:2015 number:1 pages:57-67 http://dx.doi.org/10.1109/TNS.2014.2375557 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7012118 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-PHA GBV_ILN_70 AR 62 2015 1 57-67 |
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Borghi, Giacomo ddc 620 misc medical imaging field misc fan beam misc fine grid misc reference position misc monolithic Ca-codoped LSO:Ce crystals misc calibration misc Estimation misc PET misc pencil-beam irradiation misc Crystals misc cerium misc scintillation counters misc Radiation effects misc monolithic scintillator detector misc reference events misc fan-beam method misc statistical method misc efficient fan-beam calibration procedure misc k-nearest neighbor position estimation misc gamma-ray detection misc Collimators misc monolithic scintillator detectors misc Detectors misc Spatial resolution misc digital photon counter arrays misc positron emission tomography misc tungsten slit collimator misc nearest neighbor method misc PET imaging misc Gamma rays misc Analysis misc Usage Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors |
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620 DNB Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors medical imaging field fan beam fine grid reference position monolithic Ca-codoped LSO:Ce crystals calibration Estimation PET pencil-beam irradiation Crystals cerium scintillation counters Radiation effects monolithic scintillator detector reference events fan-beam method statistical method efficient fan-beam calibration procedure k-nearest neighbor position estimation gamma-ray detection Collimators monolithic scintillator detectors Detectors Spatial resolution digital photon counter arrays positron emission tomography tungsten slit collimator nearest neighbor method PET imaging Gamma rays Analysis Usage |
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ddc 620 misc medical imaging field misc fan beam misc fine grid misc reference position misc monolithic Ca-codoped LSO:Ce crystals misc calibration misc Estimation misc PET misc pencil-beam irradiation misc Crystals misc cerium misc scintillation counters misc Radiation effects misc monolithic scintillator detector misc reference events misc fan-beam method misc statistical method misc efficient fan-beam calibration procedure misc k-nearest neighbor position estimation misc gamma-ray detection misc Collimators misc monolithic scintillator detectors misc Detectors misc Spatial resolution misc digital photon counter arrays misc positron emission tomography misc tungsten slit collimator misc nearest neighbor method misc PET imaging misc Gamma rays misc Analysis misc Usage |
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experimental validation of an efficient fan-beam calibration procedure for k-nearest neighbor position estimation in monolithic scintillator detectors |
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Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors |
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Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. |
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Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. |
| abstract_unstemmed |
Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence resolving time. However, their practical use for positron emission tomography (PET) and other applications in the medical imaging field is still limited due to drawbacks of the different methods used to estimate the position of interaction. Common statistical methods for example require the collection of an extensive dataset of reference events with a narrow pencil beam aimed at a fine grid of reference positions. Such procedures are time consuming and not straightforwardly implemented in systems composed of many detectors. Here, we experimentally demonstrate for the first time a new calibration procedure for k-nearest neighbor ( k-NN) position estimation that utilizes reference data acquired with a fan beam. The procedure is tested on two detectors consisting of 16 mm ×16 mm ×10 mm and 16 mm ×16 mm ×20 mm monolithic, Ca-codoped LSO:Ce crystals and digital photon counter (DPC) arrays. For both detectors, the spatial resolution and the bias obtained with the new method are found to be practically the same as those obtained with the previously used method based on pencil-beam irradiation, while the calibration time is reduced by a factor of ~ 20. Specifically, a FWHM of ~ 1.1 mm and a FWTM of ~ 2.7 mm were obtained using the fan-beam method with the 10 mm crystal, whereas a FWHM of ~ 1.5 mm and a FWTM of ~ 6 mm were achieved with the 20 mm crystal. Using a fan beam made with a ~ 4.5 MBq 22 Na point-source and a tungsten slit collimator with 0.5 mm aperture, the total measurement time needed to acquire the reference dataset was ~ 3 hours for the thinner crystal and ~ 2 hours for the thicker one. |
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Experimental Validation of an Efficient Fan-Beam Calibration Procedure for k-Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors |
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