The synthesis machine

The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led...
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Autor*in:	Robert F Service [verfasserIn]

Format:	Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis

Übergeordnetes Werk:	Enthalten in: Science - Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883, 347(2015), 6227, Seite 1190-1193
Übergeordnetes Werk:	volume:347 ; year:2015 ; number:6227 ; pages:1190-1193

Links:	Volltext Link aufrufen Link aufrufen

DOI / URN:	10.1126/science.347.6227.1190

Katalog-ID:	OLC1969515058

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520			\|a The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business.
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publishDate	2015
allfields	10.1126/science.347.6227.1190 doi PQ20160211 (DE-627)OLC1969515058 (DE-599)GBVOLC1969515058 (PRQ)c1856-4a04fa3badebb7595497a9f628680eabbba373bac58959776e438dc2de7a10420 (KEY)0063888920150000347622701190synthesismachine DE-627 ger DE-627 rakwb eng 500 DNB LING fid Robert F Service verfasserin aut The synthesis machine 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business. Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis Enthalten in Science Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883 347(2015), 6227, Seite 1190-1193 (DE-627)12931482X (DE-600)128410-1 (DE-576)014533189 0036-8075 nnns volume:347 year:2015 number:6227 pages:1190-1193 http://dx.doi.org/10.1126/science.347.6227.1190 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-LING SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT SSG-OLC-FOR SSG-OLC-SPO SSG-OLC-IBL SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-FOR GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_47 GBV_ILN_55 GBV_ILN_59 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_92 GBV_ILN_101 GBV_ILN_110 GBV_ILN_120 GBV_ILN_131 GBV_ILN_170 GBV_ILN_171 GBV_ILN_179 GBV_ILN_181 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_290 GBV_ILN_600 GBV_ILN_601 GBV_ILN_647 GBV_ILN_754 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2012 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2116 GBV_ILN_2120 GBV_ILN_2121 GBV_ILN_2173 GBV_ILN_2185 GBV_ILN_2219 GBV_ILN_2221 GBV_ILN_2279 GBV_ILN_2286 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4036 GBV_ILN_4046 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4320 GBV_ILN_4324 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4700 AR 347 2015 6227 1190-1193
spelling	10.1126/science.347.6227.1190 doi PQ20160211 (DE-627)OLC1969515058 (DE-599)GBVOLC1969515058 (PRQ)c1856-4a04fa3badebb7595497a9f628680eabbba373bac58959776e438dc2de7a10420 (KEY)0063888920150000347622701190synthesismachine DE-627 ger DE-627 rakwb eng 500 DNB LING fid Robert F Service verfasserin aut The synthesis machine 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business. Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis Enthalten in Science Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883 347(2015), 6227, Seite 1190-1193 (DE-627)12931482X (DE-600)128410-1 (DE-576)014533189 0036-8075 nnns volume:347 year:2015 number:6227 pages:1190-1193 http://dx.doi.org/10.1126/science.347.6227.1190 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-LING SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT SSG-OLC-FOR SSG-OLC-SPO SSG-OLC-IBL SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-FOR GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_47 GBV_ILN_55 GBV_ILN_59 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_92 GBV_ILN_101 GBV_ILN_110 GBV_ILN_120 GBV_ILN_131 GBV_ILN_170 GBV_ILN_171 GBV_ILN_179 GBV_ILN_181 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_290 GBV_ILN_600 GBV_ILN_601 GBV_ILN_647 GBV_ILN_754 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2012 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2116 GBV_ILN_2120 GBV_ILN_2121 GBV_ILN_2173 GBV_ILN_2185 GBV_ILN_2219 GBV_ILN_2221 GBV_ILN_2279 GBV_ILN_2286 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4036 GBV_ILN_4046 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4320 GBV_ILN_4324 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4700 AR 347 2015 6227 1190-1193
allfields_unstemmed	10.1126/science.347.6227.1190 doi PQ20160211 (DE-627)OLC1969515058 (DE-599)GBVOLC1969515058 (PRQ)c1856-4a04fa3badebb7595497a9f628680eabbba373bac58959776e438dc2de7a10420 (KEY)0063888920150000347622701190synthesismachine DE-627 ger DE-627 rakwb eng 500 DNB LING fid Robert F Service verfasserin aut The synthesis machine 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business. Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis Enthalten in Science Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883 347(2015), 6227, Seite 1190-1193 (DE-627)12931482X (DE-600)128410-1 (DE-576)014533189 0036-8075 nnns volume:347 year:2015 number:6227 pages:1190-1193 http://dx.doi.org/10.1126/science.347.6227.1190 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-LING SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT SSG-OLC-FOR SSG-OLC-SPO SSG-OLC-IBL SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-FOR GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_47 GBV_ILN_55 GBV_ILN_59 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_92 GBV_ILN_101 GBV_ILN_110 GBV_ILN_120 GBV_ILN_131 GBV_ILN_170 GBV_ILN_171 GBV_ILN_179 GBV_ILN_181 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_290 GBV_ILN_600 GBV_ILN_601 GBV_ILN_647 GBV_ILN_754 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2012 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2116 GBV_ILN_2120 GBV_ILN_2121 GBV_ILN_2173 GBV_ILN_2185 GBV_ILN_2219 GBV_ILN_2221 GBV_ILN_2279 GBV_ILN_2286 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4036 GBV_ILN_4046 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4320 GBV_ILN_4324 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4700 AR 347 2015 6227 1190-1193
allfieldsGer	10.1126/science.347.6227.1190 doi PQ20160211 (DE-627)OLC1969515058 (DE-599)GBVOLC1969515058 (PRQ)c1856-4a04fa3badebb7595497a9f628680eabbba373bac58959776e438dc2de7a10420 (KEY)0063888920150000347622701190synthesismachine DE-627 ger DE-627 rakwb eng 500 DNB LING fid Robert F Service verfasserin aut The synthesis machine 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business. Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis Enthalten in Science Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883 347(2015), 6227, Seite 1190-1193 (DE-627)12931482X (DE-600)128410-1 (DE-576)014533189 0036-8075 nnns volume:347 year:2015 number:6227 pages:1190-1193 http://dx.doi.org/10.1126/science.347.6227.1190 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-LING SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT SSG-OLC-FOR SSG-OLC-SPO SSG-OLC-IBL SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-FOR GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_47 GBV_ILN_55 GBV_ILN_59 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_92 GBV_ILN_101 GBV_ILN_110 GBV_ILN_120 GBV_ILN_131 GBV_ILN_170 GBV_ILN_171 GBV_ILN_179 GBV_ILN_181 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_290 GBV_ILN_600 GBV_ILN_601 GBV_ILN_647 GBV_ILN_754 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2012 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2116 GBV_ILN_2120 GBV_ILN_2121 GBV_ILN_2173 GBV_ILN_2185 GBV_ILN_2219 GBV_ILN_2221 GBV_ILN_2279 GBV_ILN_2286 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4036 GBV_ILN_4046 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4320 GBV_ILN_4324 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4700 AR 347 2015 6227 1190-1193
allfieldsSound	10.1126/science.347.6227.1190 doi PQ20160211 (DE-627)OLC1969515058 (DE-599)GBVOLC1969515058 (PRQ)c1856-4a04fa3badebb7595497a9f628680eabbba373bac58959776e438dc2de7a10420 (KEY)0063888920150000347622701190synthesismachine DE-627 ger DE-627 rakwb eng 500 DNB LING fid Robert F Service verfasserin aut The synthesis machine 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business. Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis Enthalten in Science Washington, DC : AAAS, American Assoc. for the Advancement of Science, 1883 347(2015), 6227, Seite 1190-1193 (DE-627)12931482X (DE-600)128410-1 (DE-576)014533189 0036-8075 nnns volume:347 year:2015 number:6227 pages:1190-1193 http://dx.doi.org/10.1126/science.347.6227.1190 Volltext http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-LING SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT SSG-OLC-FOR SSG-OLC-SPO SSG-OLC-IBL SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-FOR GBV_ILN_11 GBV_ILN_20 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_30 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_47 GBV_ILN_55 GBV_ILN_59 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_92 GBV_ILN_101 GBV_ILN_110 GBV_ILN_120 GBV_ILN_131 GBV_ILN_170 GBV_ILN_171 GBV_ILN_179 GBV_ILN_181 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_290 GBV_ILN_600 GBV_ILN_601 GBV_ILN_647 GBV_ILN_754 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2012 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2116 GBV_ILN_2120 GBV_ILN_2121 GBV_ILN_2173 GBV_ILN_2185 GBV_ILN_2219 GBV_ILN_2221 GBV_ILN_2279 GBV_ILN_2286 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4036 GBV_ILN_4046 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4251 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4318 GBV_ILN_4320 GBV_ILN_4324 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4700 AR 347 2015 6227 1190-1193
language	English
source	Enthalten in Science 347(2015), 6227, Seite 1190-1193 volume:347 year:2015 number:6227 pages:1190-1193
sourceStr	Enthalten in Science 347(2015), 6227, Seite 1190-1193 volume:347 year:2015 number:6227 pages:1190-1193
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Molecular chemistry Chemical synthesis Organic chemicals Chemistry Techniques, Synthetic - methods Organic Chemicals - chemical synthesis
dewey-raw	500
isfreeaccess_bool	false
container_title	Science
authorswithroles_txt_mv	Robert F Service @@aut@@
publishDateDaySort_date	2015-01-01T00:00:00Z
hierarchy_top_id	12931482X
dewey-sort	3500
id	OLC1969515058
language_de	englisch
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author	Robert F Service
spellingShingle	Robert F Service ddc 500 fid LING misc Molecular chemistry misc Chemical synthesis misc Organic chemicals misc Chemistry Techniques, Synthetic - methods misc Organic Chemicals - chemical synthesis The synthesis machine
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topic	ddc 500 fid LING misc Molecular chemistry misc Chemical synthesis misc Organic chemicals misc Chemistry Techniques, Synthetic - methods misc Organic Chemicals - chemical synthesis
topic_unstemmed	ddc 500 fid LING misc Molecular chemistry misc Chemical synthesis misc Organic chemicals misc Chemistry Techniques, Synthetic - methods misc Organic Chemicals - chemical synthesis
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abstract	The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business.
abstractGer	The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business.
abstract_unstemmed	The ability to make small organic molecules is at the heart of everything from drug development to the making of new dyes and agricultural chemicals. But ever since the dawn of synthetic organic chemistry in the 1820s, the process has required slow, painstaking effort. Now, however, researchers led by Martin Burke, a chemist at the University of Illinois, Urbana-Champaign, have developed a novel machine that may change all that. The machine automatically synthesizes new small organic molecules by welding together premade building blocks that can be put together in any configuration. Two hundred such building blocks already exist. And thousands of other similar molecules can also be used in the process. As a result, the machine has the ability to make billions of different small organic compounds that can then be tested as new drugs or for other uses. If widely adopted, the synthesis machine could revolutionize organic chemistry, turning it from a slow, painstaking process to a made-for-order business.
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title_short	The synthesis machine
url	http://dx.doi.org/10.1126/science.347.6227.1190 http://www.ncbi.nlm.nih.gov/pubmed/25766215 http://search.proquest.com/docview/1669437193
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score	7.401518

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