Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation
We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of th...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ozcelik, Damla [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: IEEE journal of selected topics in quantum electronics - New York, NY : IEEE, 1995, 22(2016), 4, Seite 1-6 |
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| Übergeordnetes Werk: |
volume:22 ; year:2016 ; number:4 ; pages:1-6 |
| Links: |
|---|
| DOI / URN: |
10.1109/JSTQE.2015.2503321 |
|---|
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OLC1974225941 |
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| 520 | |a We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. | ||
| 650 | 4 | |a Biomedical optical imaging | |
| 650 | 4 | |a Anti-resonant reflecting optical waveguides (ARROWs) | |
| 650 | 4 | |a Fluorescence | |
| 650 | 4 | |a Liquid waveguides | |
| 650 | 4 | |a Y-splitters | |
| 650 | 4 | |a biophotonics | |
| 650 | 4 | |a integrated waveguides | |
| 650 | 4 | |a Optical signal processing | |
| 650 | 4 | |a Optical waveguides | |
| 650 | 4 | |a liquid core waveguides | |
| 650 | 4 | |a Signal to noise ratio | |
| 650 | 4 | |a optofluidics | |
| 650 | 4 | |a Optical device fabrication | |
| 700 | 1 | |a Stott, Matthew A |4 oth | |
| 700 | 1 | |a Parks, Joshua W |4 oth | |
| 700 | 1 | |a Black, Jennifer A |4 oth | |
| 700 | 1 | |a Wall, Thomas A |4 oth | |
| 700 | 1 | |a Hawkins, Aaron R |4 oth | |
| 700 | 1 | |a Schmidt, Holger |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t IEEE journal of selected topics in quantum electronics |d New York, NY : IEEE, 1995 |g 22(2016), 4, Seite 1-6 |w (DE-627)184666007 |w (DE-600)1232977-0 |w (DE-576)046708901 |x 1077-260X |7 nnns |
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10.1109/JSTQE.2015.2503321 doi PQ20160430 (DE-627)OLC1974225941 (DE-599)GBVOLC1974225941 (PRQ)ieee_primary_0b00006484aeb0750 (KEY)0272399920160000022000400001signaltonoiseenhancementinopticaldetectionofsingle DE-627 ger DE-627 rakwb eng 530 620 DNB Ozcelik, Damla verfasserin aut Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. Biomedical optical imaging Anti-resonant reflecting optical waveguides (ARROWs) Fluorescence Liquid waveguides Y-splitters biophotonics integrated waveguides Optical signal processing Optical waveguides liquid core waveguides Signal to noise ratio optofluidics Optical device fabrication Stott, Matthew A oth Parks, Joshua W oth Black, Jennifer A oth Wall, Thomas A oth Hawkins, Aaron R oth Schmidt, Holger oth Enthalten in IEEE journal of selected topics in quantum electronics New York, NY : IEEE, 1995 22(2016), 4, Seite 1-6 (DE-627)184666007 (DE-600)1232977-0 (DE-576)046708901 1077-260X nnns volume:22 year:2016 number:4 pages:1-6 http://dx.doi.org/10.1109/JSTQE.2015.2503321 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_70 GBV_ILN_2006 AR 22 2016 4 1-6 |
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10.1109/JSTQE.2015.2503321 doi PQ20160430 (DE-627)OLC1974225941 (DE-599)GBVOLC1974225941 (PRQ)ieee_primary_0b00006484aeb0750 (KEY)0272399920160000022000400001signaltonoiseenhancementinopticaldetectionofsingle DE-627 ger DE-627 rakwb eng 530 620 DNB Ozcelik, Damla verfasserin aut Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. Biomedical optical imaging Anti-resonant reflecting optical waveguides (ARROWs) Fluorescence Liquid waveguides Y-splitters biophotonics integrated waveguides Optical signal processing Optical waveguides liquid core waveguides Signal to noise ratio optofluidics Optical device fabrication Stott, Matthew A oth Parks, Joshua W oth Black, Jennifer A oth Wall, Thomas A oth Hawkins, Aaron R oth Schmidt, Holger oth Enthalten in IEEE journal of selected topics in quantum electronics New York, NY : IEEE, 1995 22(2016), 4, Seite 1-6 (DE-627)184666007 (DE-600)1232977-0 (DE-576)046708901 1077-260X nnns volume:22 year:2016 number:4 pages:1-6 http://dx.doi.org/10.1109/JSTQE.2015.2503321 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_70 GBV_ILN_2006 AR 22 2016 4 1-6 |
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10.1109/JSTQE.2015.2503321 doi PQ20160430 (DE-627)OLC1974225941 (DE-599)GBVOLC1974225941 (PRQ)ieee_primary_0b00006484aeb0750 (KEY)0272399920160000022000400001signaltonoiseenhancementinopticaldetectionofsingle DE-627 ger DE-627 rakwb eng 530 620 DNB Ozcelik, Damla verfasserin aut Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. Biomedical optical imaging Anti-resonant reflecting optical waveguides (ARROWs) Fluorescence Liquid waveguides Y-splitters biophotonics integrated waveguides Optical signal processing Optical waveguides liquid core waveguides Signal to noise ratio optofluidics Optical device fabrication Stott, Matthew A oth Parks, Joshua W oth Black, Jennifer A oth Wall, Thomas A oth Hawkins, Aaron R oth Schmidt, Holger oth Enthalten in IEEE journal of selected topics in quantum electronics New York, NY : IEEE, 1995 22(2016), 4, Seite 1-6 (DE-627)184666007 (DE-600)1232977-0 (DE-576)046708901 1077-260X nnns volume:22 year:2016 number:4 pages:1-6 http://dx.doi.org/10.1109/JSTQE.2015.2503321 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_70 GBV_ILN_2006 AR 22 2016 4 1-6 |
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10.1109/JSTQE.2015.2503321 doi PQ20160430 (DE-627)OLC1974225941 (DE-599)GBVOLC1974225941 (PRQ)ieee_primary_0b00006484aeb0750 (KEY)0272399920160000022000400001signaltonoiseenhancementinopticaldetectionofsingle DE-627 ger DE-627 rakwb eng 530 620 DNB Ozcelik, Damla verfasserin aut Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. Biomedical optical imaging Anti-resonant reflecting optical waveguides (ARROWs) Fluorescence Liquid waveguides Y-splitters biophotonics integrated waveguides Optical signal processing Optical waveguides liquid core waveguides Signal to noise ratio optofluidics Optical device fabrication Stott, Matthew A oth Parks, Joshua W oth Black, Jennifer A oth Wall, Thomas A oth Hawkins, Aaron R oth Schmidt, Holger oth Enthalten in IEEE journal of selected topics in quantum electronics New York, NY : IEEE, 1995 22(2016), 4, Seite 1-6 (DE-627)184666007 (DE-600)1232977-0 (DE-576)046708901 1077-260X nnns volume:22 year:2016 number:4 pages:1-6 http://dx.doi.org/10.1109/JSTQE.2015.2503321 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_70 GBV_ILN_2006 AR 22 2016 4 1-6 |
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10.1109/JSTQE.2015.2503321 doi PQ20160430 (DE-627)OLC1974225941 (DE-599)GBVOLC1974225941 (PRQ)ieee_primary_0b00006484aeb0750 (KEY)0272399920160000022000400001signaltonoiseenhancementinopticaldetectionofsingle DE-627 ger DE-627 rakwb eng 530 620 DNB Ozcelik, Damla verfasserin aut Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. Biomedical optical imaging Anti-resonant reflecting optical waveguides (ARROWs) Fluorescence Liquid waveguides Y-splitters biophotonics integrated waveguides Optical signal processing Optical waveguides liquid core waveguides Signal to noise ratio optofluidics Optical device fabrication Stott, Matthew A oth Parks, Joshua W oth Black, Jennifer A oth Wall, Thomas A oth Hawkins, Aaron R oth Schmidt, Holger oth Enthalten in IEEE journal of selected topics in quantum electronics New York, NY : IEEE, 1995 22(2016), 4, Seite 1-6 (DE-627)184666007 (DE-600)1232977-0 (DE-576)046708901 1077-260X nnns volume:22 year:2016 number:4 pages:1-6 http://dx.doi.org/10.1109/JSTQE.2015.2503321 Volltext http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_70 GBV_ILN_2006 AR 22 2016 4 1-6 |
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Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation |
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Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation |
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Ozcelik, Damla |
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IEEE journal of selected topics in quantum electronics |
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10.1109/JSTQE.2015.2503321 |
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signal-to-noise enhancement in optical detection of single viruses with multispot excitation |
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Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation |
| abstract |
We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. |
| abstractGer |
We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. |
| abstract_unstemmed |
We present fluorescence detection of single H1N1 viruses with enhanced signal to noise ratio ( SNR ) achieved by multispot excitation in liquid-core antiresonant reflecting optical waveguides (ARROWs). Solid-core Y-splitting ARROW waveguides are fabricated orthogonal to the liquid-core section of the chip, creating multiple excitation spots for the analyte. We derive expressions for the SNR increase after signal processing, and analyze its dependence on signal levels and spot number. Very good agreement between theoretical calculations and experimental results is found. SNR enhancements up to 5×10 4 are demonstrated. |
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| title_short |
Signal-to-Noise Enhancement in Optical Detection of Single Viruses With Multispot Excitation |
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http://dx.doi.org/10.1109/JSTQE.2015.2503321 http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7336520 |
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Stott, Matthew A Parks, Joshua W Black, Jennifer A Wall, Thomas A Hawkins, Aaron R Schmidt, Holger |
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