Potential for identifying plant-based toxins on San hunter-gatherer arrowheads
The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Madelien Wooding [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: South African journal of science - Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909, 113(2017), 3/4, Seite 1 |
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| Übergeordnetes Werk: |
volume:113 ; year:2017 ; number:3/4 ; pages:1 |
| Links: |
|---|
| DOI / URN: |
10.17159/sajs.2017/20160210 |
|---|
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OLC1992598746 |
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| 520 | |a The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. | ||
| 650 | 4 | |a Flowers & plants | |
| 650 | 4 | |a Poisoning | |
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10.17159/sajs.2017/20160210 doi PQ20170721 (DE-627)OLC1992598746 (DE-599)GBVOLC1992598746 (PRQ)p936-18f5f082504be770138aef70101c9ef6e3efe857d0894215765c592ac18fdcea3 (KEY)0077498720170000113000300001potentialforidentifyingplantbasedtoxinsonsanhunter DE-627 ger DE-627 rakwb eng 910 940 DE-600 AFRIKA fid 30.00 bkl Madelien Wooding verfasserin aut Potential for identifying plant-based toxins on San hunter-gatherer arrowheads 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. Flowers & plants Poisoning Archaeology Metabolites Studies Chemical compounds African literature Justin Bradfield oth Vinesh Maharaj oth Dwayne Koot oth Lyn Wadley oth Linda Prinsloo oth Marlize Lombard oth Enthalten in South African journal of science Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909 113(2017), 3/4, Seite 1 (DE-627)130020923 (DE-600)421752-4 (DE-576)015562417 0038-2353 nnns volume:113 year:2017 number:3/4 pages:1 http://dx.doi.org/10.17159/sajs.2017/20160210 Volltext https://search.proquest.com/docview/1883094477 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-AFRIKA SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR SSG-OLC-ASS SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-ANG 30.00 AVZ AR 113 2017 3/4 1 |
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10.17159/sajs.2017/20160210 doi PQ20170721 (DE-627)OLC1992598746 (DE-599)GBVOLC1992598746 (PRQ)p936-18f5f082504be770138aef70101c9ef6e3efe857d0894215765c592ac18fdcea3 (KEY)0077498720170000113000300001potentialforidentifyingplantbasedtoxinsonsanhunter DE-627 ger DE-627 rakwb eng 910 940 DE-600 AFRIKA fid 30.00 bkl Madelien Wooding verfasserin aut Potential for identifying plant-based toxins on San hunter-gatherer arrowheads 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. Flowers & plants Poisoning Archaeology Metabolites Studies Chemical compounds African literature Justin Bradfield oth Vinesh Maharaj oth Dwayne Koot oth Lyn Wadley oth Linda Prinsloo oth Marlize Lombard oth Enthalten in South African journal of science Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909 113(2017), 3/4, Seite 1 (DE-627)130020923 (DE-600)421752-4 (DE-576)015562417 0038-2353 nnns volume:113 year:2017 number:3/4 pages:1 http://dx.doi.org/10.17159/sajs.2017/20160210 Volltext https://search.proquest.com/docview/1883094477 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-AFRIKA SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR SSG-OLC-ASS SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-ANG 30.00 AVZ AR 113 2017 3/4 1 |
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10.17159/sajs.2017/20160210 doi PQ20170721 (DE-627)OLC1992598746 (DE-599)GBVOLC1992598746 (PRQ)p936-18f5f082504be770138aef70101c9ef6e3efe857d0894215765c592ac18fdcea3 (KEY)0077498720170000113000300001potentialforidentifyingplantbasedtoxinsonsanhunter DE-627 ger DE-627 rakwb eng 910 940 DE-600 AFRIKA fid 30.00 bkl Madelien Wooding verfasserin aut Potential for identifying plant-based toxins on San hunter-gatherer arrowheads 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. Flowers & plants Poisoning Archaeology Metabolites Studies Chemical compounds African literature Justin Bradfield oth Vinesh Maharaj oth Dwayne Koot oth Lyn Wadley oth Linda Prinsloo oth Marlize Lombard oth Enthalten in South African journal of science Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909 113(2017), 3/4, Seite 1 (DE-627)130020923 (DE-600)421752-4 (DE-576)015562417 0038-2353 nnns volume:113 year:2017 number:3/4 pages:1 http://dx.doi.org/10.17159/sajs.2017/20160210 Volltext https://search.proquest.com/docview/1883094477 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-AFRIKA SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR SSG-OLC-ASS SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-ANG 30.00 AVZ AR 113 2017 3/4 1 |
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10.17159/sajs.2017/20160210 doi PQ20170721 (DE-627)OLC1992598746 (DE-599)GBVOLC1992598746 (PRQ)p936-18f5f082504be770138aef70101c9ef6e3efe857d0894215765c592ac18fdcea3 (KEY)0077498720170000113000300001potentialforidentifyingplantbasedtoxinsonsanhunter DE-627 ger DE-627 rakwb eng 910 940 DE-600 AFRIKA fid 30.00 bkl Madelien Wooding verfasserin aut Potential for identifying plant-based toxins on San hunter-gatherer arrowheads 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. Flowers & plants Poisoning Archaeology Metabolites Studies Chemical compounds African literature Justin Bradfield oth Vinesh Maharaj oth Dwayne Koot oth Lyn Wadley oth Linda Prinsloo oth Marlize Lombard oth Enthalten in South African journal of science Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909 113(2017), 3/4, Seite 1 (DE-627)130020923 (DE-600)421752-4 (DE-576)015562417 0038-2353 nnns volume:113 year:2017 number:3/4 pages:1 http://dx.doi.org/10.17159/sajs.2017/20160210 Volltext https://search.proquest.com/docview/1883094477 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-AFRIKA SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR SSG-OLC-ASS SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-ANG 30.00 AVZ AR 113 2017 3/4 1 |
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10.17159/sajs.2017/20160210 doi PQ20170721 (DE-627)OLC1992598746 (DE-599)GBVOLC1992598746 (PRQ)p936-18f5f082504be770138aef70101c9ef6e3efe857d0894215765c592ac18fdcea3 (KEY)0077498720170000113000300001potentialforidentifyingplantbasedtoxinsonsanhunter DE-627 ger DE-627 rakwb eng 910 940 DE-600 AFRIKA fid 30.00 bkl Madelien Wooding verfasserin aut Potential for identifying plant-based toxins on San hunter-gatherer arrowheads 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. Flowers & plants Poisoning Archaeology Metabolites Studies Chemical compounds African literature Justin Bradfield oth Vinesh Maharaj oth Dwayne Koot oth Lyn Wadley oth Linda Prinsloo oth Marlize Lombard oth Enthalten in South African journal of science Johannesburg [u.a.] : [Verlag nicht ermittelbar], 1909 113(2017), 3/4, Seite 1 (DE-627)130020923 (DE-600)421752-4 (DE-576)015562417 0038-2353 nnns volume:113 year:2017 number:3/4 pages:1 http://dx.doi.org/10.17159/sajs.2017/20160210 Volltext https://search.proquest.com/docview/1883094477 GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-AFRIKA SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR SSG-OLC-ASS SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-ANG 30.00 AVZ AR 113 2017 3/4 1 |
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Potential for identifying plant-based toxins on San hunter-gatherer arrowheads |
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The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. |
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The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. |
| abstract_unstemmed |
The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative byproducts of toxic compounds. |
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Potential for identifying plant-based toxins on San hunter-gatherer arrowheads |
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