Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7)
A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characteri...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Abdel-Hafez, Shams H [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2017 |
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| Rechteinformationen: |
Nutzungsrecht: © 2017 Taylor & Francis Group, LLC 2017 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Phosphorus, sulfur and silicon and the related elements - Philadelphia, Pa [u.a.] : Taylor & Francis, 1989, 192(2017), 10, Seite 1114 |
|---|---|
| Übergeordnetes Werk: |
volume:192 ; year:2017 ; number:10 ; pages:1114 |
| Links: |
|---|
| DOI / URN: |
10.1080/10426507.2017.1333505 |
|---|
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OLC1996852078 |
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| 520 | |a A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characterized using spectroscopic tools (IR, 1 H NMR, 13 C NMR, and mass spectroscopy) as well as microanalysis. Our study reveals that compound vitamin E/selenated nicotine moiety has the highest cytotoxic effect than the other synthesized compounds. | ||
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| 650 | 4 | |a Cytotoxicity | |
| 650 | 4 | |a Vitamin E | |
| 650 | 4 | |a Nicotine | |
| 650 | 4 | |a Tocopherol | |
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Synthesis | |
| 650 | 4 | |a Nuclear magnetic resonance | |
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10.1080/10426507.2017.1333505 doi PQ20171125 (DE-627)OLC1996852078 (DE-599)GBVOLC1996852078 (PRQ)i847-95ca2aef3e6bdf214674e1767ee61bfbc2cd4bd144a6f32e8c93837954229fa80 (KEY)0015125420170000192001001114designsynthesisandcytotoxicactivityofvitaminebeari DE-627 ger DE-627 rakwb eng 660 540 DE-600 Abdel-Hafez, Shams H verfasserin aut Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) 2017 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characterized using spectroscopic tools (IR, 1 H NMR, 13 C NMR, and mass spectroscopy) as well as microanalysis. Our study reveals that compound vitamin E/selenated nicotine moiety has the highest cytotoxic effect than the other synthesized compounds. Nutzungsrecht: © 2017 Taylor & Francis Group, LLC 2017 Cytotoxic activity dipyridyldiselenide dinicotinyldiselenide vitamin E dicoumarinyldiselenide dipyridazinyldiselenide Selenium compounds Cytotoxicity Vitamin E Nicotine Tocopherol Breast cancer Synthesis Nuclear magnetic resonance Mass spectroscopy Cancer Abdelwahab, Ahmed B oth Kirsch, Gilbert oth Enthalten in Phosphorus, sulfur and silicon and the related elements Philadelphia, Pa [u.a.] : Taylor & Francis, 1989 192(2017), 10, Seite 1114 (DE-627)130784885 (DE-600)1004997-6 (DE-576)017720621 1042-6507 nnns volume:192 year:2017 number:10 pages:1114 http://dx.doi.org/10.1080/10426507.2017.1333505 Volltext http://www.tandfonline.com/doi/abs/10.1080/10426507.2017.1333505 https://search.proquest.com/docview/1941394997 GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 GBV_ILN_4305 AR 192 2017 10 1114 |
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660 540 DE-600 Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) Cytotoxic activity dipyridyldiselenide dinicotinyldiselenide vitamin E dicoumarinyldiselenide dipyridazinyldiselenide Selenium compounds Cytotoxicity Vitamin E Nicotine Tocopherol Breast cancer Synthesis Nuclear magnetic resonance Mass spectroscopy Cancer |
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ddc 660 misc Cytotoxic activity misc dipyridyldiselenide misc dinicotinyldiselenide misc vitamin E misc dicoumarinyldiselenide misc dipyridazinyldiselenide misc Selenium compounds misc Cytotoxicity misc Vitamin E misc Nicotine misc Tocopherol misc Breast cancer misc Synthesis misc Nuclear magnetic resonance misc Mass spectroscopy misc Cancer |
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ddc 660 misc Cytotoxic activity misc dipyridyldiselenide misc dinicotinyldiselenide misc vitamin E misc dicoumarinyldiselenide misc dipyridazinyldiselenide misc Selenium compounds misc Cytotoxicity misc Vitamin E misc Nicotine misc Tocopherol misc Breast cancer misc Synthesis misc Nuclear magnetic resonance misc Mass spectroscopy misc Cancer |
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ddc 660 misc Cytotoxic activity misc dipyridyldiselenide misc dinicotinyldiselenide misc vitamin E misc dicoumarinyldiselenide misc dipyridazinyldiselenide misc Selenium compounds misc Cytotoxicity misc Vitamin E misc Nicotine misc Tocopherol misc Breast cancer misc Synthesis misc Nuclear magnetic resonance misc Mass spectroscopy misc Cancer |
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Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) |
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Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) |
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Abdel-Hafez, Shams H |
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Phosphorus, sulfur and silicon and the related elements |
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design, synthesis and cytotoxic activity of vitamin e bearing selenium compounds against human breast cancer cell line (mcf-7) |
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Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) |
| abstract |
A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characterized using spectroscopic tools (IR, 1 H NMR, 13 C NMR, and mass spectroscopy) as well as microanalysis. Our study reveals that compound vitamin E/selenated nicotine moiety has the highest cytotoxic effect than the other synthesized compounds. |
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A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characterized using spectroscopic tools (IR, 1 H NMR, 13 C NMR, and mass spectroscopy) as well as microanalysis. Our study reveals that compound vitamin E/selenated nicotine moiety has the highest cytotoxic effect than the other synthesized compounds. |
| abstract_unstemmed |
A new series of vitamin E/selenated pyridine, vitamin E/selenated pyridazine, vitamin E/selenated coumarine and vitamin E/selenated nicotine moieties were synthesized and their cytotoxic activity is investigated using the human breast cancer cell line. The newly synthesized compounds were characterized using spectroscopic tools (IR, 1 H NMR, 13 C NMR, and mass spectroscopy) as well as microanalysis. Our study reveals that compound vitamin E/selenated nicotine moiety has the highest cytotoxic effect than the other synthesized compounds. |
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Design, synthesis and cytotoxic activity of vitamin E bearing selenium compounds against human breast cancer cell line (MCF-7) |
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