Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD)
Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial functio...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ukawa, Teiji [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2012 |
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| Schlagwörter: |
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| Anmerkung: |
© International Federation for Medical and Biological Engineering 2012 |
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| Übergeordnetes Werk: |
Enthalten in: Medical & biological engineering & computing - Springer-Verlag, 1977, 50(2012), 12 vom: 30. Sept., Seite 1239-1247 |
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| Übergeordnetes Werk: |
volume:50 ; year:2012 ; number:12 ; day:30 ; month:09 ; pages:1239-1247 |
| Links: |
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| DOI / URN: |
10.1007/s11517-012-0955-z |
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| Katalog-ID: |
OLC2038690316 |
|---|
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| 245 | 1 | 0 | |a Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) |
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| 520 | |a Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. | ||
| 650 | 4 | |a Atherosclerosis | |
| 650 | 4 | |a Endothelial function | |
| 650 | 4 | |a FMD | |
| 650 | 4 | |a Oscillometric sphygmomanometer | |
| 650 | 4 | |a ezFMD | |
| 700 | 1 | |a Takayanagi, Tsuneo |4 aut | |
| 700 | 1 | |a Morimoto, Haruka |4 aut | |
| 700 | 1 | |a Higashi, Yukihito |4 aut | |
| 700 | 1 | |a Idei, Naomi |4 aut | |
| 700 | 1 | |a Yoshizumi, Masao |4 aut | |
| 700 | 1 | |a Tsuji, Toshio |4 aut | |
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10.1007/s11517-012-0955-z doi (DE-627)OLC2038690316 (DE-He213)s11517-012-0955-z-p DE-627 ger DE-627 rakwb eng 610 660 570 VZ 12 ssgn Ukawa, Teiji verfasserin aut Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © International Federation for Medical and Biological Engineering 2012 Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. Atherosclerosis Endothelial function FMD Oscillometric sphygmomanometer ezFMD Takayanagi, Tsuneo aut Morimoto, Haruka aut Higashi, Yukihito aut Idei, Naomi aut Yoshizumi, Masao aut Tsuji, Toshio aut Enthalten in Medical & biological engineering & computing Springer-Verlag, 1977 50(2012), 12 vom: 30. Sept., Seite 1239-1247 (DE-627)129858552 (DE-600)282327-5 (DE-576)015165507 0140-0118 nnns volume:50 year:2012 number:12 day:30 month:09 pages:1239-1247 https://doi.org/10.1007/s11517-012-0955-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-MAT GBV_ILN_32 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4219 AR 50 2012 12 30 09 1239-1247 |
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10.1007/s11517-012-0955-z doi (DE-627)OLC2038690316 (DE-He213)s11517-012-0955-z-p DE-627 ger DE-627 rakwb eng 610 660 570 VZ 12 ssgn Ukawa, Teiji verfasserin aut Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © International Federation for Medical and Biological Engineering 2012 Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. Atherosclerosis Endothelial function FMD Oscillometric sphygmomanometer ezFMD Takayanagi, Tsuneo aut Morimoto, Haruka aut Higashi, Yukihito aut Idei, Naomi aut Yoshizumi, Masao aut Tsuji, Toshio aut Enthalten in Medical & biological engineering & computing Springer-Verlag, 1977 50(2012), 12 vom: 30. Sept., Seite 1239-1247 (DE-627)129858552 (DE-600)282327-5 (DE-576)015165507 0140-0118 nnns volume:50 year:2012 number:12 day:30 month:09 pages:1239-1247 https://doi.org/10.1007/s11517-012-0955-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-MAT GBV_ILN_32 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4219 AR 50 2012 12 30 09 1239-1247 |
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10.1007/s11517-012-0955-z doi (DE-627)OLC2038690316 (DE-He213)s11517-012-0955-z-p DE-627 ger DE-627 rakwb eng 610 660 570 VZ 12 ssgn Ukawa, Teiji verfasserin aut Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © International Federation for Medical and Biological Engineering 2012 Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. Atherosclerosis Endothelial function FMD Oscillometric sphygmomanometer ezFMD Takayanagi, Tsuneo aut Morimoto, Haruka aut Higashi, Yukihito aut Idei, Naomi aut Yoshizumi, Masao aut Tsuji, Toshio aut Enthalten in Medical & biological engineering & computing Springer-Verlag, 1977 50(2012), 12 vom: 30. Sept., Seite 1239-1247 (DE-627)129858552 (DE-600)282327-5 (DE-576)015165507 0140-0118 nnns volume:50 year:2012 number:12 day:30 month:09 pages:1239-1247 https://doi.org/10.1007/s11517-012-0955-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-MAT GBV_ILN_32 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4219 AR 50 2012 12 30 09 1239-1247 |
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10.1007/s11517-012-0955-z doi (DE-627)OLC2038690316 (DE-He213)s11517-012-0955-z-p DE-627 ger DE-627 rakwb eng 610 660 570 VZ 12 ssgn Ukawa, Teiji verfasserin aut Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © International Federation for Medical and Biological Engineering 2012 Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. Atherosclerosis Endothelial function FMD Oscillometric sphygmomanometer ezFMD Takayanagi, Tsuneo aut Morimoto, Haruka aut Higashi, Yukihito aut Idei, Naomi aut Yoshizumi, Masao aut Tsuji, Toshio aut Enthalten in Medical & biological engineering & computing Springer-Verlag, 1977 50(2012), 12 vom: 30. Sept., Seite 1239-1247 (DE-627)129858552 (DE-600)282327-5 (DE-576)015165507 0140-0118 nnns volume:50 year:2012 number:12 day:30 month:09 pages:1239-1247 https://doi.org/10.1007/s11517-012-0955-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-MAT GBV_ILN_32 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4219 AR 50 2012 12 30 09 1239-1247 |
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10.1007/s11517-012-0955-z doi (DE-627)OLC2038690316 (DE-He213)s11517-012-0955-z-p DE-627 ger DE-627 rakwb eng 610 660 570 VZ 12 ssgn Ukawa, Teiji verfasserin aut Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © International Federation for Medical and Biological Engineering 2012 Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. Atherosclerosis Endothelial function FMD Oscillometric sphygmomanometer ezFMD Takayanagi, Tsuneo aut Morimoto, Haruka aut Higashi, Yukihito aut Idei, Naomi aut Yoshizumi, Masao aut Tsuji, Toshio aut Enthalten in Medical & biological engineering & computing Springer-Verlag, 1977 50(2012), 12 vom: 30. Sept., Seite 1239-1247 (DE-627)129858552 (DE-600)282327-5 (DE-576)015165507 0140-0118 nnns volume:50 year:2012 number:12 day:30 month:09 pages:1239-1247 https://doi.org/10.1007/s11517-012-0955-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 SSG-OPC-MAT GBV_ILN_32 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4219 AR 50 2012 12 30 09 1239-1247 |
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Ukawa, Teiji @@aut@@ Takayanagi, Tsuneo @@aut@@ Morimoto, Haruka @@aut@@ Higashi, Yukihito @@aut@@ Idei, Naomi @@aut@@ Yoshizumi, Masao @@aut@@ Tsuji, Toshio @@aut@@ |
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novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezfmd) |
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Novel non-invasive method of measurement of endothelial function: enclosed-zone flow-mediated dilatation (ezFMD) |
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Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. © International Federation for Medical and Biological Engineering 2012 |
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Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. © International Federation for Medical and Biological Engineering 2012 |
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Abstract Measurement of flow-mediated dilatation (FMD) is the conventional non-invasive method for assessment of endothelial function; however, it requires an expensive ultrasound system and high levels of technical skill. Therefore, we developed a novel method for measurement of endothelial function, namely, measurement of ezFMD. ezFMD estimates the degree of vasodilatation from the oscillation signals transmitted to a sphygmomanometer cuff attached to the upper arm. The objective of this study was to validate the principle underlying the measurement of ezFMD, and to evaluate the repeatability of the ezFMD measurements. We observed the blood vessel behavior and oscillometric pattern in ten subjects. When the cuff was inflated to the level of the mean blood pressure, the oscillation amplitude increased with increasing degree of vasodilatation. In experiment to evaluate the repeatability of the ezFMD measurement, the average difference between the paired measurements was 3.7 %, the standard deviation was 11.5 %, and the average coefficient of variation value for the 11 paired measurements was 23.7 %. These results suggest the validity of the principle underlying the measurement of the ezFMD for the assessment of endothelial function. And, this study suggests that the repeatability of the ezFMD measurements is superior to that of the conventional measurement of FMD. © International Federation for Medical and Biological Engineering 2012 |
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