Preparation and characterization of composite hydrogel beads based on sodium alginate
Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OS...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hu, Yan [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag Berlin Heidelberg 2015 |
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| Übergeordnetes Werk: |
Enthalten in: Polymer bulletin - Springer Berlin Heidelberg, 1978, 72(2015), 11 vom: 30. Juni, Seite 2857-2869 |
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| Übergeordnetes Werk: |
volume:72 ; year:2015 ; number:11 ; day:30 ; month:06 ; pages:2857-2869 |
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|---|
| DOI / URN: |
10.1007/s00289-015-1440-2 |
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| 520 | |a Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. | ||
| 650 | 4 | |a Sodium alginate | |
| 650 | 4 | |a Oxidized sodium alginate | |
| 650 | 4 | |a Hydrogel beads | |
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| 700 | 1 | |a Chen, Tao |4 aut | |
| 700 | 1 | |a Dong, Xiaoying |4 aut | |
| 700 | 1 | |a Mei, Zhinan |4 aut | |
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10.1007/s00289-015-1440-2 doi (DE-627)OLC204264661X (DE-He213)s00289-015-1440-2-p DE-627 ger DE-627 rakwb eng 540 530 660 VZ BIODIV DE-30 fid Hu, Yan verfasserin aut Preparation and characterization of composite hydrogel beads based on sodium alginate 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. Sodium alginate Oxidized sodium alginate Hydrogel beads Preparation Chen, Tao aut Dong, Xiaoying aut Mei, Zhinan aut Enthalten in Polymer bulletin Springer Berlin Heidelberg, 1978 72(2015), 11 vom: 30. Juni, Seite 2857-2869 (DE-627)129092916 (DE-600)6871-8 (DE-576)01442861X 0170-0839 nnns volume:72 year:2015 number:11 day:30 month:06 pages:2857-2869 https://doi.org/10.1007/s00289-015-1440-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 AR 72 2015 11 30 06 2857-2869 |
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10.1007/s00289-015-1440-2 doi (DE-627)OLC204264661X (DE-He213)s00289-015-1440-2-p DE-627 ger DE-627 rakwb eng 540 530 660 VZ BIODIV DE-30 fid Hu, Yan verfasserin aut Preparation and characterization of composite hydrogel beads based on sodium alginate 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. Sodium alginate Oxidized sodium alginate Hydrogel beads Preparation Chen, Tao aut Dong, Xiaoying aut Mei, Zhinan aut Enthalten in Polymer bulletin Springer Berlin Heidelberg, 1978 72(2015), 11 vom: 30. Juni, Seite 2857-2869 (DE-627)129092916 (DE-600)6871-8 (DE-576)01442861X 0170-0839 nnns volume:72 year:2015 number:11 day:30 month:06 pages:2857-2869 https://doi.org/10.1007/s00289-015-1440-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 AR 72 2015 11 30 06 2857-2869 |
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10.1007/s00289-015-1440-2 doi (DE-627)OLC204264661X (DE-He213)s00289-015-1440-2-p DE-627 ger DE-627 rakwb eng 540 530 660 VZ BIODIV DE-30 fid Hu, Yan verfasserin aut Preparation and characterization of composite hydrogel beads based on sodium alginate 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. Sodium alginate Oxidized sodium alginate Hydrogel beads Preparation Chen, Tao aut Dong, Xiaoying aut Mei, Zhinan aut Enthalten in Polymer bulletin Springer Berlin Heidelberg, 1978 72(2015), 11 vom: 30. Juni, Seite 2857-2869 (DE-627)129092916 (DE-600)6871-8 (DE-576)01442861X 0170-0839 nnns volume:72 year:2015 number:11 day:30 month:06 pages:2857-2869 https://doi.org/10.1007/s00289-015-1440-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 AR 72 2015 11 30 06 2857-2869 |
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10.1007/s00289-015-1440-2 doi (DE-627)OLC204264661X (DE-He213)s00289-015-1440-2-p DE-627 ger DE-627 rakwb eng 540 530 660 VZ BIODIV DE-30 fid Hu, Yan verfasserin aut Preparation and characterization of composite hydrogel beads based on sodium alginate 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. Sodium alginate Oxidized sodium alginate Hydrogel beads Preparation Chen, Tao aut Dong, Xiaoying aut Mei, Zhinan aut Enthalten in Polymer bulletin Springer Berlin Heidelberg, 1978 72(2015), 11 vom: 30. Juni, Seite 2857-2869 (DE-627)129092916 (DE-600)6871-8 (DE-576)01442861X 0170-0839 nnns volume:72 year:2015 number:11 day:30 month:06 pages:2857-2869 https://doi.org/10.1007/s00289-015-1440-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 AR 72 2015 11 30 06 2857-2869 |
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10.1007/s00289-015-1440-2 doi (DE-627)OLC204264661X (DE-He213)s00289-015-1440-2-p DE-627 ger DE-627 rakwb eng 540 530 660 VZ BIODIV DE-30 fid Hu, Yan verfasserin aut Preparation and characterization of composite hydrogel beads based on sodium alginate 2015 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. Sodium alginate Oxidized sodium alginate Hydrogel beads Preparation Chen, Tao aut Dong, Xiaoying aut Mei, Zhinan aut Enthalten in Polymer bulletin Springer Berlin Heidelberg, 1978 72(2015), 11 vom: 30. Juni, Seite 2857-2869 (DE-627)129092916 (DE-600)6871-8 (DE-576)01442861X 0170-0839 nnns volume:72 year:2015 number:11 day:30 month:06 pages:2857-2869 https://doi.org/10.1007/s00289-015-1440-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 AR 72 2015 11 30 06 2857-2869 |
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Preparation and characterization of composite hydrogel beads based on sodium alginate |
| abstract |
Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. © Springer-Verlag Berlin Heidelberg 2015 |
| abstractGer |
Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. © Springer-Verlag Berlin Heidelberg 2015 |
| abstract_unstemmed |
Abstract In this report, novel biopolymer hydrogels composed of sodium alginate (SA) and the oxidized sodium alginate (OSA) with an interpenetrating polymer network (IPN) structure were prepared by a combination of chemical and ionic cross-linking approaches. By using SA as the main raw material, OSA was obtained using sodium periodate. The gelation process of the IPN hydrogels was the formation of dual network: one gelatin network cross-linked by OSA with dihydrazide and another SA network cross-linked by $ Ca^{2+} $. The factors which affect its swelling properties were discussed. The best swelling ratio of the beads was 2300, and the swelling property was greatly affected by pH and preparation condition. The stability and swelling behavior of OSA/SA gel beads were better improved than the pure SA/$ Ca^{2+} $ system. The OSA/SA hydrogel beads with the pH sensitivity and stability will be a good candidate for site-specific controlled drug release carrier. © Springer-Verlag Berlin Heidelberg 2015 |
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GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-TEC SSG-OLC-PHY SSG-OLC-CHE GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4277 |
| container_issue |
11 |
| title_short |
Preparation and characterization of composite hydrogel beads based on sodium alginate |
| url |
https://doi.org/10.1007/s00289-015-1440-2 |
| remote_bool |
false |
| author2 |
Chen, Tao Dong, Xiaoying Mei, Zhinan |
| author2Str |
Chen, Tao Dong, Xiaoying Mei, Zhinan |
| ppnlink |
129092916 |
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| hochschulschrift_bool |
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| doi_str |
10.1007/s00289-015-1440-2 |
| up_date |
2024-07-03T16:06:31.920Z |
| _version_ |
1803574619063451648 |
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