A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery
Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ma, Shengpu [verfasserIn] |
|---|
| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2010 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer Science+Business Media, LLC 2010 |
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| Übergeordnetes Werk: |
Enthalten in: Journal of porous materials - Springer US, 1995, 18(2010), 2 vom: 11. März, Seite 233-239 |
|---|---|
| Übergeordnetes Werk: |
volume:18 ; year:2010 ; number:2 ; day:11 ; month:03 ; pages:233-239 |
| Links: |
|---|
| DOI / URN: |
10.1007/s10934-010-9375-3 |
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OLC2043004026 |
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| 520 | |a Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. | ||
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10.1007/s10934-010-9375-3 doi (DE-627)OLC2043004026 (DE-He213)s10934-010-9375-3-p DE-627 ger DE-627 rakwb eng 530 VZ Ma, Shengpu verfasserin aut A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery 2010 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC 2010 Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. Mesoporous silica nanoparticles Drug storage Pulsed pressure drop Drug delivery Wang, Yanqin aut Zhu, Yingchun aut Enthalten in Journal of porous materials Springer US, 1995 18(2010), 2 vom: 11. März, Seite 233-239 (DE-627)211471933 (DE-600)1322952-7 (DE-576)121196038 1380-2224 nnns volume:18 year:2010 number:2 day:11 month:03 pages:233-239 https://doi.org/10.1007/s10934-010-9375-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-GEO SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 18 2010 2 11 03 233-239 |
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10.1007/s10934-010-9375-3 doi (DE-627)OLC2043004026 (DE-He213)s10934-010-9375-3-p DE-627 ger DE-627 rakwb eng 530 VZ Ma, Shengpu verfasserin aut A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery 2010 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC 2010 Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. Mesoporous silica nanoparticles Drug storage Pulsed pressure drop Drug delivery Wang, Yanqin aut Zhu, Yingchun aut Enthalten in Journal of porous materials Springer US, 1995 18(2010), 2 vom: 11. März, Seite 233-239 (DE-627)211471933 (DE-600)1322952-7 (DE-576)121196038 1380-2224 nnns volume:18 year:2010 number:2 day:11 month:03 pages:233-239 https://doi.org/10.1007/s10934-010-9375-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-GEO SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 18 2010 2 11 03 233-239 |
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10.1007/s10934-010-9375-3 doi (DE-627)OLC2043004026 (DE-He213)s10934-010-9375-3-p DE-627 ger DE-627 rakwb eng 530 VZ Ma, Shengpu verfasserin aut A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery 2010 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC 2010 Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. Mesoporous silica nanoparticles Drug storage Pulsed pressure drop Drug delivery Wang, Yanqin aut Zhu, Yingchun aut Enthalten in Journal of porous materials Springer US, 1995 18(2010), 2 vom: 11. März, Seite 233-239 (DE-627)211471933 (DE-600)1322952-7 (DE-576)121196038 1380-2224 nnns volume:18 year:2010 number:2 day:11 month:03 pages:233-239 https://doi.org/10.1007/s10934-010-9375-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-GEO SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 18 2010 2 11 03 233-239 |
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10.1007/s10934-010-9375-3 doi (DE-627)OLC2043004026 (DE-He213)s10934-010-9375-3-p DE-627 ger DE-627 rakwb eng 530 VZ Ma, Shengpu verfasserin aut A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery 2010 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC 2010 Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. Mesoporous silica nanoparticles Drug storage Pulsed pressure drop Drug delivery Wang, Yanqin aut Zhu, Yingchun aut Enthalten in Journal of porous materials Springer US, 1995 18(2010), 2 vom: 11. März, Seite 233-239 (DE-627)211471933 (DE-600)1322952-7 (DE-576)121196038 1380-2224 nnns volume:18 year:2010 number:2 day:11 month:03 pages:233-239 https://doi.org/10.1007/s10934-010-9375-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-GEO SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 18 2010 2 11 03 233-239 |
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Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. © Springer Science+Business Media, LLC 2010 |
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Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. © Springer Science+Business Media, LLC 2010 |
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Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. Powder X-ray diffraction studies showed that the quantity of n-hexane added into the solution was critical for the ordering of the final mesostructures. The particle size of MSN was between 200 and 400 nm, which is suitable for endocytosis by human cells. The drug loading capability of MSN prepared through this route was measured and the influence of the pulsed pressure drop on drug delivery was studied. This study showed that the delivery rate of ibuprofen in a simulated body fluid solution increased dramatically under the pulsed pressure drop. © Springer Science+Business Media, LLC 2010 |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2043004026</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230510090415.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200819s2010 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s10934-010-9375-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2043004026</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s10934-010-9375-3-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ma, Shengpu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A simple room temperature synthesis of mesoporous silica nanoparticles for drug storage and pressure pulsed delivery</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2010</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer Science+Business Media, LLC 2010</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Mesoporous silica nanoparticles (MSN) have been synthesized at room temperature under assistance of n-hexane by using tetraethyl orthosilicate (TEOS) as a silica source and cetyltrimethylammonium bromide (CTAB) as a structure directing agent. 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