Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart
Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectr...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Weiss, Kilian [verfasserIn] |
|---|
| Format: |
Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2012 |
|---|
| Schlagwörter: |
|---|
| Systematik: |
|
|---|
| Anmerkung: |
© Springer-Verlag 2012 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Applied magnetic resonance - Springer Vienna, 1990, 43(2012), 1-2 vom: 19. Mai, Seite 275-288 |
|---|---|
| Übergeordnetes Werk: |
volume:43 ; year:2012 ; number:1-2 ; day:19 ; month:05 ; pages:275-288 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00723-012-0349-2 |
|---|
| Katalog-ID: |
OLC2043924540 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2043924540 | ||
| 003 | DE-627 | ||
| 005 | 20230502145507.0 | ||
| 007 | tu | ||
| 008 | 200820s2012 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00723-012-0349-2 |2 doi | |
| 035 | |a (DE-627)OLC2043924540 | ||
| 035 | |a (DE-He213)s00723-012-0349-2-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 530 |a 620 |q VZ |
| 084 | |a UA 2242.9 |q VZ |2 rvk | ||
| 084 | |a 53.00 |2 bkl | ||
| 084 | |a 33.00 |2 bkl | ||
| 100 | 1 | |a Weiss, Kilian |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| 264 | 1 | |c 2012 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © Springer-Verlag 2012 | ||
| 520 | |a Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. | ||
| 650 | 4 | |a Pyruvate | |
| 650 | 4 | |a Dynamic Nuclear Polarization | |
| 650 | 4 | |a Spectroscopic Imaging | |
| 650 | 4 | |a Perfuse Heart | |
| 650 | 4 | |a Magnetic Resonance Spectroscopic Imaging | |
| 700 | 1 | |a Mariotti, Erika |4 aut | |
| 700 | 1 | |a Hill, Deborah K. |4 aut | |
| 700 | 1 | |a Orton, Matthew R. |4 aut | |
| 700 | 1 | |a Dunn, Joel T. |4 aut | |
| 700 | 1 | |a Medina, Rodolfo A. |4 aut | |
| 700 | 1 | |a Southworth, Richard |4 aut | |
| 700 | 1 | |a Kozerke, Sebastian |4 aut | |
| 700 | 1 | |a Eykyn, Thomas R. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Applied magnetic resonance |d Springer Vienna, 1990 |g 43(2012), 1-2 vom: 19. Mai, Seite 275-288 |w (DE-627)13092427X |w (DE-600)1054553-0 |w (DE-576)02803757X |x 0937-9347 |7 nnns |
| 773 | 1 | 8 | |g volume:43 |g year:2012 |g number:1-2 |g day:19 |g month:05 |g pages:275-288 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s00723-012-0349-2 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-TEC | ||
| 912 | |a SSG-OLC-PHY | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_2010 | ||
| 936 | r | v | |a UA 2242.9 |
| 936 | b | k | |a 53.00 |q VZ |
| 936 | b | k | |a 33.00 |q VZ |
| 951 | |a AR | ||
| 952 | |d 43 |j 2012 |e 1-2 |b 19 |c 05 |h 275-288 | ||
| author_variant |
k w kw e m em d k h dk dkh m r o mr mro j t d jt jtd r a m ra ram r s rs s k sk t r e tr tre |
|---|---|
| matchkey_str |
article:09379347:2012----::eeoigyeplrzd3setocpadmgnfreaoisuisnh |
| hierarchy_sort_str |
2012 |
| bklnumber |
53.00 33.00 |
| publishDate |
2012 |
| allfields |
10.1007/s00723-012-0349-2 doi (DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p DE-627 ger DE-627 rakwb eng 530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Weiss, Kilian verfasserin aut Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2012 Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging Mariotti, Erika aut Hill, Deborah K. aut Orton, Matthew R. aut Dunn, Joel T. aut Medina, Rodolfo A. aut Southworth, Richard aut Kozerke, Sebastian aut Eykyn, Thomas R. aut Enthalten in Applied magnetic resonance Springer Vienna, 1990 43(2012), 1-2 vom: 19. Mai, Seite 275-288 (DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X 0937-9347 nnns volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 https://doi.org/10.1007/s00723-012-0349-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 UA 2242.9 53.00 VZ 33.00 VZ AR 43 2012 1-2 19 05 275-288 |
| spelling |
10.1007/s00723-012-0349-2 doi (DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p DE-627 ger DE-627 rakwb eng 530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Weiss, Kilian verfasserin aut Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2012 Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging Mariotti, Erika aut Hill, Deborah K. aut Orton, Matthew R. aut Dunn, Joel T. aut Medina, Rodolfo A. aut Southworth, Richard aut Kozerke, Sebastian aut Eykyn, Thomas R. aut Enthalten in Applied magnetic resonance Springer Vienna, 1990 43(2012), 1-2 vom: 19. Mai, Seite 275-288 (DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X 0937-9347 nnns volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 https://doi.org/10.1007/s00723-012-0349-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 UA 2242.9 53.00 VZ 33.00 VZ AR 43 2012 1-2 19 05 275-288 |
| allfields_unstemmed |
10.1007/s00723-012-0349-2 doi (DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p DE-627 ger DE-627 rakwb eng 530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Weiss, Kilian verfasserin aut Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2012 Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging Mariotti, Erika aut Hill, Deborah K. aut Orton, Matthew R. aut Dunn, Joel T. aut Medina, Rodolfo A. aut Southworth, Richard aut Kozerke, Sebastian aut Eykyn, Thomas R. aut Enthalten in Applied magnetic resonance Springer Vienna, 1990 43(2012), 1-2 vom: 19. Mai, Seite 275-288 (DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X 0937-9347 nnns volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 https://doi.org/10.1007/s00723-012-0349-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 UA 2242.9 53.00 VZ 33.00 VZ AR 43 2012 1-2 19 05 275-288 |
| allfieldsGer |
10.1007/s00723-012-0349-2 doi (DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p DE-627 ger DE-627 rakwb eng 530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Weiss, Kilian verfasserin aut Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2012 Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging Mariotti, Erika aut Hill, Deborah K. aut Orton, Matthew R. aut Dunn, Joel T. aut Medina, Rodolfo A. aut Southworth, Richard aut Kozerke, Sebastian aut Eykyn, Thomas R. aut Enthalten in Applied magnetic resonance Springer Vienna, 1990 43(2012), 1-2 vom: 19. Mai, Seite 275-288 (DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X 0937-9347 nnns volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 https://doi.org/10.1007/s00723-012-0349-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 UA 2242.9 53.00 VZ 33.00 VZ AR 43 2012 1-2 19 05 275-288 |
| allfieldsSound |
10.1007/s00723-012-0349-2 doi (DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p DE-627 ger DE-627 rakwb eng 530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Weiss, Kilian verfasserin aut Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart 2012 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2012 Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging Mariotti, Erika aut Hill, Deborah K. aut Orton, Matthew R. aut Dunn, Joel T. aut Medina, Rodolfo A. aut Southworth, Richard aut Kozerke, Sebastian aut Eykyn, Thomas R. aut Enthalten in Applied magnetic resonance Springer Vienna, 1990 43(2012), 1-2 vom: 19. Mai, Seite 275-288 (DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X 0937-9347 nnns volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 https://doi.org/10.1007/s00723-012-0349-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 UA 2242.9 53.00 VZ 33.00 VZ AR 43 2012 1-2 19 05 275-288 |
| language |
English |
| source |
Enthalten in Applied magnetic resonance 43(2012), 1-2 vom: 19. Mai, Seite 275-288 volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 |
| sourceStr |
Enthalten in Applied magnetic resonance 43(2012), 1-2 vom: 19. Mai, Seite 275-288 volume:43 year:2012 number:1-2 day:19 month:05 pages:275-288 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging |
| dewey-raw |
530 |
| isfreeaccess_bool |
false |
| container_title |
Applied magnetic resonance |
| authorswithroles_txt_mv |
Weiss, Kilian @@aut@@ Mariotti, Erika @@aut@@ Hill, Deborah K. @@aut@@ Orton, Matthew R. @@aut@@ Dunn, Joel T. @@aut@@ Medina, Rodolfo A. @@aut@@ Southworth, Richard @@aut@@ Kozerke, Sebastian @@aut@@ Eykyn, Thomas R. @@aut@@ |
| publishDateDaySort_date |
2012-05-19T00:00:00Z |
| hierarchy_top_id |
13092427X |
| dewey-sort |
3530 |
| id |
OLC2043924540 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2043924540</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502145507.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2012 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00723-012-0349-2</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2043924540</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00723-012-0349-2-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="a">620</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">UA 2242.9</subfield><subfield code="q">VZ</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Weiss, Kilian</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 2012</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pyruvate</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dynamic Nuclear Polarization</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Spectroscopic Imaging</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Perfuse Heart</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Magnetic Resonance Spectroscopic Imaging</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mariotti, Erika</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hill, Deborah K.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Orton, Matthew R.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dunn, Joel T.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Medina, Rodolfo A.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Southworth, Richard</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kozerke, Sebastian</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eykyn, Thomas R.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Applied magnetic resonance</subfield><subfield code="d">Springer Vienna, 1990</subfield><subfield code="g">43(2012), 1-2 vom: 19. Mai, Seite 275-288</subfield><subfield code="w">(DE-627)13092427X</subfield><subfield code="w">(DE-600)1054553-0</subfield><subfield code="w">(DE-576)02803757X</subfield><subfield code="x">0937-9347</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:43</subfield><subfield code="g">year:2012</subfield><subfield code="g">number:1-2</subfield><subfield code="g">day:19</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:275-288</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00723-012-0349-2</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-TEC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="936" ind1="r" ind2="v"><subfield code="a">UA 2242.9</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">33.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">43</subfield><subfield code="j">2012</subfield><subfield code="e">1-2</subfield><subfield code="b">19</subfield><subfield code="c">05</subfield><subfield code="h">275-288</subfield></datafield></record></collection>
|
| author |
Weiss, Kilian |
| spellingShingle |
Weiss, Kilian ddc 530 rvk UA 2242.9 bkl 53.00 bkl 33.00 misc Pyruvate misc Dynamic Nuclear Polarization misc Spectroscopic Imaging misc Perfuse Heart misc Magnetic Resonance Spectroscopic Imaging Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| authorStr |
Weiss, Kilian |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)13092427X |
| format |
Article |
| dewey-ones |
530 - Physics 620 - Engineering & allied operations |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut aut |
| collection |
OLC |
| remote_str |
false |
| illustrated |
Not Illustrated |
| issn |
0937-9347 |
| topic_title |
530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart Pyruvate Dynamic Nuclear Polarization Spectroscopic Imaging Perfuse Heart Magnetic Resonance Spectroscopic Imaging |
| topic |
ddc 530 rvk UA 2242.9 bkl 53.00 bkl 33.00 misc Pyruvate misc Dynamic Nuclear Polarization misc Spectroscopic Imaging misc Perfuse Heart misc Magnetic Resonance Spectroscopic Imaging |
| topic_unstemmed |
ddc 530 rvk UA 2242.9 bkl 53.00 bkl 33.00 misc Pyruvate misc Dynamic Nuclear Polarization misc Spectroscopic Imaging misc Perfuse Heart misc Magnetic Resonance Spectroscopic Imaging |
| topic_browse |
ddc 530 rvk UA 2242.9 bkl 53.00 bkl 33.00 misc Pyruvate misc Dynamic Nuclear Polarization misc Spectroscopic Imaging misc Perfuse Heart misc Magnetic Resonance Spectroscopic Imaging |
| format_facet |
Aufsätze Gedruckte Aufsätze |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
nc |
| hierarchy_parent_title |
Applied magnetic resonance |
| hierarchy_parent_id |
13092427X |
| dewey-tens |
530 - Physics 620 - Engineering |
| hierarchy_top_title |
Applied magnetic resonance |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)13092427X (DE-600)1054553-0 (DE-576)02803757X |
| title |
Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| ctrlnum |
(DE-627)OLC2043924540 (DE-He213)s00723-012-0349-2-p |
| title_full |
Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| author_sort |
Weiss, Kilian |
| journal |
Applied magnetic resonance |
| journalStr |
Applied magnetic resonance |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology |
| recordtype |
marc |
| publishDateSort |
2012 |
| contenttype_str_mv |
txt |
| container_start_page |
275 |
| author_browse |
Weiss, Kilian Mariotti, Erika Hill, Deborah K. Orton, Matthew R. Dunn, Joel T. Medina, Rodolfo A. Southworth, Richard Kozerke, Sebastian Eykyn, Thomas R. |
| container_volume |
43 |
| class |
530 620 VZ UA 2242.9 VZ rvk 53.00 bkl 33.00 bkl |
| format_se |
Aufsätze |
| author-letter |
Weiss, Kilian |
| doi_str_mv |
10.1007/s00723-012-0349-2 |
| dewey-full |
530 620 |
| title_sort |
developing hyperpolarized 13c spectroscopy and imaging for metabolic studies in the isolated perfused rat heart |
| title_auth |
Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| abstract |
Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. © Springer-Verlag 2012 |
| abstractGer |
Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. © Springer-Verlag 2012 |
| abstract_unstemmed |
Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production. © Springer-Verlag 2012 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-PHY GBV_ILN_65 GBV_ILN_70 GBV_ILN_2010 |
| container_issue |
1-2 |
| title_short |
Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart |
| url |
https://doi.org/10.1007/s00723-012-0349-2 |
| remote_bool |
false |
| author2 |
Mariotti, Erika Hill, Deborah K. Orton, Matthew R. Dunn, Joel T. Medina, Rodolfo A. Southworth, Richard Kozerke, Sebastian Eykyn, Thomas R. |
| author2Str |
Mariotti, Erika Hill, Deborah K. Orton, Matthew R. Dunn, Joel T. Medina, Rodolfo A. Southworth, Richard Kozerke, Sebastian Eykyn, Thomas R. |
| ppnlink |
13092427X |
| mediatype_str_mv |
n |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00723-012-0349-2 |
| up_date |
2024-07-03T21:19:29.615Z |
| _version_ |
1803594308904812544 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2043924540</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502145507.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2012 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00723-012-0349-2</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2043924540</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00723-012-0349-2-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="a">620</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">UA 2242.9</subfield><subfield code="q">VZ</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">53.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Weiss, Kilian</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Developing Hyperpolarized 13C Spectroscopy and Imaging for Metabolic Studies in the Isolated Perfused Rat Heart</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 2012</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Hyperpolarized 13C magnetic resonance is a powerful tool for the study of cardiac metabolism. In this work, we have implemented protocols for the real-time hyperpolarized 13C investigation of Langendorff-perfused rat hearts using both non-selective non-localized spectroscopy and fast spectroscopic imaging. Following [1-13C] pyruvate infusion, we observed both catabolic and anaplerotic metabolic processes resulting in a number of metabolites, including bicarbonate, carbon dioxide, lactate, alanine and aspartate. Employing fast spectroscopic imaging, we were able to observe regional variations in pyruvate perfusion as well as in lactate and bicarbonate production.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pyruvate</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dynamic Nuclear Polarization</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Spectroscopic Imaging</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Perfuse Heart</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Magnetic Resonance Spectroscopic Imaging</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mariotti, Erika</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hill, Deborah K.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Orton, Matthew R.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dunn, Joel T.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Medina, Rodolfo A.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Southworth, Richard</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kozerke, Sebastian</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eykyn, Thomas R.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Applied magnetic resonance</subfield><subfield code="d">Springer Vienna, 1990</subfield><subfield code="g">43(2012), 1-2 vom: 19. Mai, Seite 275-288</subfield><subfield code="w">(DE-627)13092427X</subfield><subfield code="w">(DE-600)1054553-0</subfield><subfield code="w">(DE-576)02803757X</subfield><subfield code="x">0937-9347</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:43</subfield><subfield code="g">year:2012</subfield><subfield code="g">number:1-2</subfield><subfield code="g">day:19</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:275-288</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00723-012-0349-2</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-TEC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="936" ind1="r" ind2="v"><subfield code="a">UA 2242.9</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">53.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">33.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">43</subfield><subfield code="j">2012</subfield><subfield code="e">1-2</subfield><subfield code="b">19</subfield><subfield code="c">05</subfield><subfield code="h">275-288</subfield></datafield></record></collection>
|
| score |
7.4028378 |