Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions
Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Levine, Rachel E. [verfasserIn] |
|---|
| Format: |
Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2019 |
|---|
| Schlagwörter: |
|---|
| Anmerkung: |
© Springer Science+Business Media, LLC, part of Springer Nature 2019 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Bulletin of environmental contamination and toxicology - Springer US, 1966, 103(2019), 6 vom: 10. Okt., Seite 808-813 |
|---|---|
| Übergeordnetes Werk: |
volume:103 ; year:2019 ; number:6 ; day:10 ; month:10 ; pages:808-813 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00128-019-02727-6 |
|---|
| Katalog-ID: |
OLC2062936125 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2062936125 | ||
| 003 | DE-627 | ||
| 005 | 20230602174008.0 | ||
| 007 | tu | ||
| 008 | 200820s2019 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00128-019-02727-6 |2 doi | |
| 035 | |a (DE-627)OLC2062936125 | ||
| 035 | |a (DE-He213)s00128-019-02727-6-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 333.7 |a 610 |q VZ |
| 084 | |a 43.00 |2 bkl | ||
| 100 | 1 | |a Levine, Rachel E. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © Springer Science+Business Media, LLC, part of Springer Nature 2019 | ||
| 520 | |a Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. | ||
| 650 | 4 | |a Antibiotic | |
| 650 | 4 | |a Microbial biotransformation | |
| 650 | 4 | |a Background nutrients | |
| 650 | 4 | |a Microbial composition | |
| 650 | 4 | |a Biotransformation products | |
| 700 | 1 | |a Zhang, Yuping |4 aut | |
| 700 | 1 | |a Leng, Yifei |4 aut | |
| 700 | 1 | |a Snow, Daniel D. |4 aut | |
| 700 | 1 | |a Cassada, David |4 aut | |
| 700 | 1 | |a Durso, Lisa M. |4 aut | |
| 700 | 1 | |a Li, Xu |0 (orcid)0000-0002-1006-3027 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Bulletin of environmental contamination and toxicology |d Springer US, 1966 |g 103(2019), 6 vom: 10. Okt., Seite 808-813 |w (DE-627)129093009 |w (DE-600)6895-0 |w (DE-576)014428717 |x 0007-4861 |7 nnns |
| 773 | 1 | 8 | |g volume:103 |g year:2019 |g number:6 |g day:10 |g month:10 |g pages:808-813 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s00128-019-02727-6 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-UMW | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_252 | ||
| 912 | |a GBV_ILN_2018 | ||
| 936 | b | k | |a 43.00 |q VZ |
| 951 | |a AR | ||
| 952 | |d 103 |j 2019 |e 6 |b 10 |c 10 |h 808-813 | ||
| author_variant |
r e l re rel y z yz y l yl d d s dd dds d c dc l m d lm lmd x l xl |
|---|---|
| matchkey_str |
article:00074861:2019----::irbatasomtooaufnmdatboiudraiubc |
| hierarchy_sort_str |
2019 |
| bklnumber |
43.00 |
| publishDate |
2019 |
| allfields |
10.1007/s00128-019-02727-6 doi (DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.00 bkl Levine, Rachel E. verfasserin aut Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions 2019 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products Zhang, Yuping aut Leng, Yifei aut Snow, Daniel D. aut Cassada, David aut Durso, Lisa M. aut Li, Xu (orcid)0000-0002-1006-3027 aut Enthalten in Bulletin of environmental contamination and toxicology Springer US, 1966 103(2019), 6 vom: 10. Okt., Seite 808-813 (DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 0007-4861 nnns volume:103 year:2019 number:6 day:10 month:10 pages:808-813 https://doi.org/10.1007/s00128-019-02727-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 43.00 VZ AR 103 2019 6 10 10 808-813 |
| spelling |
10.1007/s00128-019-02727-6 doi (DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.00 bkl Levine, Rachel E. verfasserin aut Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions 2019 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products Zhang, Yuping aut Leng, Yifei aut Snow, Daniel D. aut Cassada, David aut Durso, Lisa M. aut Li, Xu (orcid)0000-0002-1006-3027 aut Enthalten in Bulletin of environmental contamination and toxicology Springer US, 1966 103(2019), 6 vom: 10. Okt., Seite 808-813 (DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 0007-4861 nnns volume:103 year:2019 number:6 day:10 month:10 pages:808-813 https://doi.org/10.1007/s00128-019-02727-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 43.00 VZ AR 103 2019 6 10 10 808-813 |
| allfields_unstemmed |
10.1007/s00128-019-02727-6 doi (DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.00 bkl Levine, Rachel E. verfasserin aut Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions 2019 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products Zhang, Yuping aut Leng, Yifei aut Snow, Daniel D. aut Cassada, David aut Durso, Lisa M. aut Li, Xu (orcid)0000-0002-1006-3027 aut Enthalten in Bulletin of environmental contamination and toxicology Springer US, 1966 103(2019), 6 vom: 10. Okt., Seite 808-813 (DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 0007-4861 nnns volume:103 year:2019 number:6 day:10 month:10 pages:808-813 https://doi.org/10.1007/s00128-019-02727-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 43.00 VZ AR 103 2019 6 10 10 808-813 |
| allfieldsGer |
10.1007/s00128-019-02727-6 doi (DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.00 bkl Levine, Rachel E. verfasserin aut Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions 2019 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products Zhang, Yuping aut Leng, Yifei aut Snow, Daniel D. aut Cassada, David aut Durso, Lisa M. aut Li, Xu (orcid)0000-0002-1006-3027 aut Enthalten in Bulletin of environmental contamination and toxicology Springer US, 1966 103(2019), 6 vom: 10. Okt., Seite 808-813 (DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 0007-4861 nnns volume:103 year:2019 number:6 day:10 month:10 pages:808-813 https://doi.org/10.1007/s00128-019-02727-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 43.00 VZ AR 103 2019 6 10 10 808-813 |
| allfieldsSound |
10.1007/s00128-019-02727-6 doi (DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ 43.00 bkl Levine, Rachel E. verfasserin aut Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions 2019 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products Zhang, Yuping aut Leng, Yifei aut Snow, Daniel D. aut Cassada, David aut Durso, Lisa M. aut Li, Xu (orcid)0000-0002-1006-3027 aut Enthalten in Bulletin of environmental contamination and toxicology Springer US, 1966 103(2019), 6 vom: 10. Okt., Seite 808-813 (DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 0007-4861 nnns volume:103 year:2019 number:6 day:10 month:10 pages:808-813 https://doi.org/10.1007/s00128-019-02727-6 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 43.00 VZ AR 103 2019 6 10 10 808-813 |
| language |
English |
| source |
Enthalten in Bulletin of environmental contamination and toxicology 103(2019), 6 vom: 10. Okt., Seite 808-813 volume:103 year:2019 number:6 day:10 month:10 pages:808-813 |
| sourceStr |
Enthalten in Bulletin of environmental contamination and toxicology 103(2019), 6 vom: 10. Okt., Seite 808-813 volume:103 year:2019 number:6 day:10 month:10 pages:808-813 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products |
| dewey-raw |
333.7 |
| isfreeaccess_bool |
false |
| container_title |
Bulletin of environmental contamination and toxicology |
| authorswithroles_txt_mv |
Levine, Rachel E. @@aut@@ Zhang, Yuping @@aut@@ Leng, Yifei @@aut@@ Snow, Daniel D. @@aut@@ Cassada, David @@aut@@ Durso, Lisa M. @@aut@@ Li, Xu @@aut@@ |
| publishDateDaySort_date |
2019-10-10T00:00:00Z |
| hierarchy_top_id |
129093009 |
| dewey-sort |
3333.7 |
| id |
OLC2062936125 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2062936125</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230602174008.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2019 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00128-019-02727-6</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2062936125</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00128-019-02727-6-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">333.7</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Levine, Rachel E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer Science+Business Media, LLC, part of Springer Nature 2019</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antibiotic</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial biotransformation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Background nutrients</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial composition</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biotransformation products</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Yuping</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Leng, Yifei</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Snow, Daniel D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cassada, David</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Durso, Lisa M.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Xu</subfield><subfield code="0">(orcid)0000-0002-1006-3027</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Bulletin of environmental contamination and toxicology</subfield><subfield code="d">Springer US, 1966</subfield><subfield code="g">103(2019), 6 vom: 10. Okt., Seite 808-813</subfield><subfield code="w">(DE-627)129093009</subfield><subfield code="w">(DE-600)6895-0</subfield><subfield code="w">(DE-576)014428717</subfield><subfield code="x">0007-4861</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:103</subfield><subfield code="g">year:2019</subfield><subfield code="g">number:6</subfield><subfield code="g">day:10</subfield><subfield code="g">month:10</subfield><subfield code="g">pages:808-813</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00128-019-02727-6</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-UMW</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_252</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">103</subfield><subfield code="j">2019</subfield><subfield code="e">6</subfield><subfield code="b">10</subfield><subfield code="c">10</subfield><subfield code="h">808-813</subfield></datafield></record></collection>
|
| author |
Levine, Rachel E. |
| spellingShingle |
Levine, Rachel E. ddc 333.7 bkl 43.00 misc Antibiotic misc Microbial biotransformation misc Background nutrients misc Microbial composition misc Biotransformation products Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| authorStr |
Levine, Rachel E. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)129093009 |
| format |
Article |
| dewey-ones |
333 - Economics of land & energy 610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut |
| collection |
OLC |
| remote_str |
false |
| illustrated |
Not Illustrated |
| issn |
0007-4861 |
| topic_title |
333.7 610 VZ 43.00 bkl Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions Antibiotic Microbial biotransformation Background nutrients Microbial composition Biotransformation products |
| topic |
ddc 333.7 bkl 43.00 misc Antibiotic misc Microbial biotransformation misc Background nutrients misc Microbial composition misc Biotransformation products |
| topic_unstemmed |
ddc 333.7 bkl 43.00 misc Antibiotic misc Microbial biotransformation misc Background nutrients misc Microbial composition misc Biotransformation products |
| topic_browse |
ddc 333.7 bkl 43.00 misc Antibiotic misc Microbial biotransformation misc Background nutrients misc Microbial composition misc Biotransformation products |
| format_facet |
Aufsätze Gedruckte Aufsätze |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
nc |
| hierarchy_parent_title |
Bulletin of environmental contamination and toxicology |
| hierarchy_parent_id |
129093009 |
| dewey-tens |
330 - Economics 610 - Medicine & health |
| hierarchy_top_title |
Bulletin of environmental contamination and toxicology |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)129093009 (DE-600)6895-0 (DE-576)014428717 |
| title |
Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| ctrlnum |
(DE-627)OLC2062936125 (DE-He213)s00128-019-02727-6-p |
| title_full |
Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| author_sort |
Levine, Rachel E. |
| journal |
Bulletin of environmental contamination and toxicology |
| journalStr |
Bulletin of environmental contamination and toxicology |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
300 - Social sciences 600 - Technology |
| recordtype |
marc |
| publishDateSort |
2019 |
| contenttype_str_mv |
txt |
| container_start_page |
808 |
| author_browse |
Levine, Rachel E. Zhang, Yuping Leng, Yifei Snow, Daniel D. Cassada, David Durso, Lisa M. Li, Xu |
| container_volume |
103 |
| class |
333.7 610 VZ 43.00 bkl |
| format_se |
Aufsätze |
| author-letter |
Levine, Rachel E. |
| doi_str_mv |
10.1007/s00128-019-02727-6 |
| normlink |
(ORCID)0000-0002-1006-3027 |
| normlink_prefix_str_mv |
(orcid)0000-0002-1006-3027 |
| dewey-full |
333.7 610 |
| title_sort |
microbial transformation of a sulfonamide antibiotic under various background nutrient conditions |
| title_auth |
Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| abstract |
Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. © Springer Science+Business Media, LLC, part of Springer Nature 2019 |
| abstractGer |
Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. © Springer Science+Business Media, LLC, part of Springer Nature 2019 |
| abstract_unstemmed |
Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment. © Springer Science+Business Media, LLC, part of Springer Nature 2019 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-PHA GBV_ILN_70 GBV_ILN_252 GBV_ILN_2018 |
| container_issue |
6 |
| title_short |
Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions |
| url |
https://doi.org/10.1007/s00128-019-02727-6 |
| remote_bool |
false |
| author2 |
Zhang, Yuping Leng, Yifei Snow, Daniel D. Cassada, David Durso, Lisa M. Li, Xu |
| author2Str |
Zhang, Yuping Leng, Yifei Snow, Daniel D. Cassada, David Durso, Lisa M. Li, Xu |
| ppnlink |
129093009 |
| mediatype_str_mv |
n |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00128-019-02727-6 |
| up_date |
2024-07-03T17:01:54.704Z |
| _version_ |
1803578103255007232 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2062936125</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230602174008.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2019 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00128-019-02727-6</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2062936125</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00128-019-02727-6-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">333.7</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">43.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Levine, Rachel E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Microbial Transformation of A Sulfonamide Antibiotic Under Various Background Nutrient Conditions</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer Science+Business Media, LLC, part of Springer Nature 2019</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Certain microbes can biotransform antibiotics. Little is known about these microbes or the biotransformation processes. The objective of this study was to determine the effects of background nutrient conditions on a sulfonamide degrading culture and on its biotransformation of sulfadiazine (SDZ) with respect to transformation kinetics and transformation products. The mixed culture capable of degrading SDZ consisted primarily of three genera, Brevibacterium, Castellaniella and Leucobacter. The maximum biotransformation rate was 4.55 mg $ L^{−1} $ $ d^{−1} $ in the absence of background nutrients. Among the three background nutrient conditions tested, diluted R2A medium lead to the highest maximum SDZ biotransformation rates, followed by humic acid and glucose. 2-aminopyrimidine was the major SDZ biotransformation product under the background nutrient conditions tested, while another previously reported biotransformation product, sulfanilic acid, was further degraded by the mixed culture. The findings from this study can help improve our estimation of the fate of antibiotics in the environment.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antibiotic</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial biotransformation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Background nutrients</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbial composition</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biotransformation products</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Yuping</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Leng, Yifei</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Snow, Daniel D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cassada, David</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Durso, Lisa M.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Xu</subfield><subfield code="0">(orcid)0000-0002-1006-3027</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Bulletin of environmental contamination and toxicology</subfield><subfield code="d">Springer US, 1966</subfield><subfield code="g">103(2019), 6 vom: 10. Okt., Seite 808-813</subfield><subfield code="w">(DE-627)129093009</subfield><subfield code="w">(DE-600)6895-0</subfield><subfield code="w">(DE-576)014428717</subfield><subfield code="x">0007-4861</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:103</subfield><subfield code="g">year:2019</subfield><subfield code="g">number:6</subfield><subfield code="g">day:10</subfield><subfield code="g">month:10</subfield><subfield code="g">pages:808-813</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00128-019-02727-6</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-UMW</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_252</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">43.00</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">103</subfield><subfield code="j">2019</subfield><subfield code="e">6</subfield><subfield code="b">10</subfield><subfield code="c">10</subfield><subfield code="h">808-813</subfield></datafield></record></collection>
|
| score |
7.4002314 |