Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions
Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room tem...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Chikhacheva, I. P. [verfasserIn] |
|---|
| Format: |
Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Anmerkung: |
© Pleiades Publishing, Ltd. 2018 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Russian journal of applied chemistry - Pleiades Publishing, 1993, 91(2018), 2 vom: Feb., Seite 325-329 |
|---|---|
| Übergeordnetes Werk: |
volume:91 ; year:2018 ; number:2 ; month:02 ; pages:325-329 |
| Links: |
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| DOI / URN: |
10.1134/S1070427218020246 |
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OLC206365798X |
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| 520 | |a Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. | ||
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10.1134/S1070427218020246 doi (DE-627)OLC206365798X (DE-He213)S1070427218020246-p DE-627 ger DE-627 rakwb eng 540 VZ Chikhacheva, I. P. verfasserin aut Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions 2018 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Pleiades Publishing, Ltd. 2018 Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. Shumova, T. B. aut Khokhlachev, O. F. aut Novikova, O. B. aut Enthalten in Russian journal of applied chemistry Pleiades Publishing, 1993 91(2018), 2 vom: Feb., Seite 325-329 (DE-627)181999927 (DE-600)1181520-6 (DE-576)038881543 1070-4272 nnns volume:91 year:2018 number:2 month:02 pages:325-329 https://doi.org/10.1134/S1070427218020246 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 91 2018 2 02 325-329 |
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10.1134/S1070427218020246 doi (DE-627)OLC206365798X (DE-He213)S1070427218020246-p DE-627 ger DE-627 rakwb eng 540 VZ Chikhacheva, I. P. verfasserin aut Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions 2018 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Pleiades Publishing, Ltd. 2018 Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. Shumova, T. B. aut Khokhlachev, O. F. aut Novikova, O. B. aut Enthalten in Russian journal of applied chemistry Pleiades Publishing, 1993 91(2018), 2 vom: Feb., Seite 325-329 (DE-627)181999927 (DE-600)1181520-6 (DE-576)038881543 1070-4272 nnns volume:91 year:2018 number:2 month:02 pages:325-329 https://doi.org/10.1134/S1070427218020246 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 91 2018 2 02 325-329 |
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10.1134/S1070427218020246 doi (DE-627)OLC206365798X (DE-He213)S1070427218020246-p DE-627 ger DE-627 rakwb eng 540 VZ Chikhacheva, I. P. verfasserin aut Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions 2018 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Pleiades Publishing, Ltd. 2018 Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. Shumova, T. B. aut Khokhlachev, O. F. aut Novikova, O. B. aut Enthalten in Russian journal of applied chemistry Pleiades Publishing, 1993 91(2018), 2 vom: Feb., Seite 325-329 (DE-627)181999927 (DE-600)1181520-6 (DE-576)038881543 1070-4272 nnns volume:91 year:2018 number:2 month:02 pages:325-329 https://doi.org/10.1134/S1070427218020246 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 91 2018 2 02 325-329 |
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10.1134/S1070427218020246 doi (DE-627)OLC206365798X (DE-He213)S1070427218020246-p DE-627 ger DE-627 rakwb eng 540 VZ Chikhacheva, I. P. verfasserin aut Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions 2018 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Pleiades Publishing, Ltd. 2018 Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. Shumova, T. B. aut Khokhlachev, O. F. aut Novikova, O. B. aut Enthalten in Russian journal of applied chemistry Pleiades Publishing, 1993 91(2018), 2 vom: Feb., Seite 325-329 (DE-627)181999927 (DE-600)1181520-6 (DE-576)038881543 1070-4272 nnns volume:91 year:2018 number:2 month:02 pages:325-329 https://doi.org/10.1134/S1070427218020246 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE SSG-OLC-PHA SSG-OLC-DE-84 GBV_ILN_70 AR 91 2018 2 02 325-329 |
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Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. © Pleiades Publishing, Ltd. 2018 |
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Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. © Pleiades Publishing, Ltd. 2018 |
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Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. A procedure for preparing a hydrosol stable at room temperature in the presence of a stabilizer was examined. The hydrosol obtained, in which the collapsed polymer with the captured antigen acts as a solid support, can be used for agglutination with a complementary antibody, i.e., the immunochemical reaction can be evaluated visually. © Pleiades Publishing, Ltd. 2018 |
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P.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Use of Specific Properties of Poly-N-vinylcaprolactam in Immunochemical Reactions</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Pleiades Publishing, Ltd. 2018</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Principal possibility of using a smart polymer, poly-N-vinylcaprolactam, for immobilization of biopharmaceuticals (antibodies and antigens) in the course of phase transition of a soluble coil into an insoluble globule was demonstrated. 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