Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean
Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Kannan, Narayanan [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
1989 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag New York Inc. 1989 |
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| Übergeordnetes Werk: |
Enthalten in: Archives of environmental contamination and toxicology - Springer-Verlag, 1973, 18(1989), 6 vom: Nov., Seite 850-857 |
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| Übergeordnetes Werk: |
volume:18 ; year:1989 ; number:6 ; month:11 ; pages:850-857 |
| Links: |
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| DOI / URN: |
10.1007/BF01160300 |
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| Katalog-ID: |
OLC2070684016 |
|---|
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| 100 | 1 | |a Kannan, Narayanan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
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| 520 | |a Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. | ||
| 650 | 4 | |a PCBs | |
| 650 | 4 | |a Biphenyl | |
| 650 | 4 | |a Penta | |
| 650 | 4 | |a Bioaccumulation | |
| 650 | 4 | |a Marine Mammal | |
| 700 | 1 | |a Tanabe, Shinsuke |4 aut | |
| 700 | 1 | |a Ono, Mitsuhiro |4 aut | |
| 700 | 1 | |a Tatsukawa, Ryo |4 aut | |
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10.1007/BF01160300 doi (DE-627)OLC2070684016 (DE-He213)BF01160300-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ Kannan, Narayanan verfasserin aut Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean 1989 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag New York Inc. 1989 Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. PCBs Biphenyl Penta Bioaccumulation Marine Mammal Tanabe, Shinsuke aut Ono, Mitsuhiro aut Tatsukawa, Ryo aut Enthalten in Archives of environmental contamination and toxicology Springer-Verlag, 1973 18(1989), 6 vom: Nov., Seite 850-857 (DE-627)129397725 (DE-600)185986-9 (DE-576)01478100X 0090-4341 nnns volume:18 year:1989 number:6 month:11 pages:850-857 https://doi.org/10.1007/BF01160300 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_70 GBV_ILN_130 GBV_ILN_154 GBV_ILN_252 GBV_ILN_601 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4103 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4307 GBV_ILN_4313 AR 18 1989 6 11 850-857 |
| spelling |
10.1007/BF01160300 doi (DE-627)OLC2070684016 (DE-He213)BF01160300-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ Kannan, Narayanan verfasserin aut Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean 1989 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag New York Inc. 1989 Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. PCBs Biphenyl Penta Bioaccumulation Marine Mammal Tanabe, Shinsuke aut Ono, Mitsuhiro aut Tatsukawa, Ryo aut Enthalten in Archives of environmental contamination and toxicology Springer-Verlag, 1973 18(1989), 6 vom: Nov., Seite 850-857 (DE-627)129397725 (DE-600)185986-9 (DE-576)01478100X 0090-4341 nnns volume:18 year:1989 number:6 month:11 pages:850-857 https://doi.org/10.1007/BF01160300 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_70 GBV_ILN_130 GBV_ILN_154 GBV_ILN_252 GBV_ILN_601 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4103 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4307 GBV_ILN_4313 AR 18 1989 6 11 850-857 |
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10.1007/BF01160300 doi (DE-627)OLC2070684016 (DE-He213)BF01160300-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ Kannan, Narayanan verfasserin aut Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean 1989 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag New York Inc. 1989 Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. PCBs Biphenyl Penta Bioaccumulation Marine Mammal Tanabe, Shinsuke aut Ono, Mitsuhiro aut Tatsukawa, Ryo aut Enthalten in Archives of environmental contamination and toxicology Springer-Verlag, 1973 18(1989), 6 vom: Nov., Seite 850-857 (DE-627)129397725 (DE-600)185986-9 (DE-576)01478100X 0090-4341 nnns volume:18 year:1989 number:6 month:11 pages:850-857 https://doi.org/10.1007/BF01160300 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_70 GBV_ILN_130 GBV_ILN_154 GBV_ILN_252 GBV_ILN_601 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4103 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4307 GBV_ILN_4313 AR 18 1989 6 11 850-857 |
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10.1007/BF01160300 doi (DE-627)OLC2070684016 (DE-He213)BF01160300-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ Kannan, Narayanan verfasserin aut Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean 1989 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag New York Inc. 1989 Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. PCBs Biphenyl Penta Bioaccumulation Marine Mammal Tanabe, Shinsuke aut Ono, Mitsuhiro aut Tatsukawa, Ryo aut Enthalten in Archives of environmental contamination and toxicology Springer-Verlag, 1973 18(1989), 6 vom: Nov., Seite 850-857 (DE-627)129397725 (DE-600)185986-9 (DE-576)01478100X 0090-4341 nnns volume:18 year:1989 number:6 month:11 pages:850-857 https://doi.org/10.1007/BF01160300 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_70 GBV_ILN_130 GBV_ILN_154 GBV_ILN_252 GBV_ILN_601 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4103 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4307 GBV_ILN_4313 AR 18 1989 6 11 850-857 |
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10.1007/BF01160300 doi (DE-627)OLC2070684016 (DE-He213)BF01160300-p DE-627 ger DE-627 rakwb eng 333.7 610 VZ Kannan, Narayanan verfasserin aut Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean 1989 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag New York Inc. 1989 Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. PCBs Biphenyl Penta Bioaccumulation Marine Mammal Tanabe, Shinsuke aut Ono, Mitsuhiro aut Tatsukawa, Ryo aut Enthalten in Archives of environmental contamination and toxicology Springer-Verlag, 1973 18(1989), 6 vom: Nov., Seite 850-857 (DE-627)129397725 (DE-600)185986-9 (DE-576)01478100X 0090-4341 nnns volume:18 year:1989 number:6 month:11 pages:850-857 https://doi.org/10.1007/BF01160300 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_23 GBV_ILN_70 GBV_ILN_130 GBV_ILN_154 GBV_ILN_252 GBV_ILN_601 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4103 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4307 GBV_ILN_4313 AR 18 1989 6 11 850-857 |
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Enthalten in Archives of environmental contamination and toxicology 18(1989), 6 vom: Nov., Seite 850-857 volume:18 year:1989 number:6 month:11 pages:850-857 |
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Kannan, Narayanan @@aut@@ Tanabe, Shinsuke @@aut@@ Ono, Mitsuhiro @@aut@@ Tatsukawa, Ryo @@aut@@ |
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Kannan, Narayanan |
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Kannan, Narayanan ddc 333.7 misc PCBs misc Biphenyl misc Penta misc Bioaccumulation misc Marine Mammal Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
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333.7 610 VZ Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean PCBs Biphenyl Penta Bioaccumulation Marine Mammal |
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Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
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Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
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critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
| title_auth |
Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean |
| abstract |
Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. © Springer-Verlag New York Inc. 1989 |
| abstractGer |
Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. © Springer-Verlag New York Inc. 1989 |
| abstract_unstemmed |
Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern. © Springer-Verlag New York Inc. 1989 |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2070684016</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230324031705.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200819s1989 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF01160300</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2070684016</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)BF01160300-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">333.7</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Kannan, Narayanan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Critical evaluation of polychlorinated biphenyl toxicity in terrestrial and marine mammals: Increasing impact of non-ortho and mono-ortho coplanar polychlorinated biphenyls from land to ocean</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1989</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag New York Inc. 1989</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Residues of potentially toxic non-ortho chlorine substituted coplanar 3,3′,4,4′-tetra-,3,3′,4,4′,5-penta-, 3,3′,4,4′,5,5′-hexachlorobiphenyl and their mono- and di-ortho analogs (2,3′,4,4′,5-penta-, 2,3,3′,4,4′-penta-, 2,3,3′,4,4′,5-hexa-and 2,2′,3,3′,4,4′-hexa-, 2,2′,3,4,4′,5-hexa-chlorobiphenyl) were determined in humans, dogs, cats (terrestrial), a finless porpoise (Neophocoena phocoenoides-coastal), Dall's porpoises (Phocoenoides dalli,dalli), Baird's beaked whales (Berardius bairdii) and killer whales (Orcinus orca-open ocean). Among the coplanar polychlorinated biphenyl (PCB) congeners, the concentration of the di-ortho congeners was the highest and the non-ortho congeners was the lowest. However, all three coplanar PCBs occurred at significantly higher levels than toxic polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). The relative bioconcentration and metabolic capacity of terrestrial and marine mammals to these chemicals, suggest that the toxic threat of coplanar PCBs increases from land to ocean, but the reverse is true for PCDDs and PCDFs. The toxic threat of coplanar PCBs to higher aquatic predators such as cetaceans was principally assessed by 2,3,7,8-$ T_{4} $CDD Toxic Equivalent Analysis which is based on the induction of arylhydrocarbon hydroxylase (AHH) and ethoxyresorufinO-deethylase (EROD). Analysis indicates, in particular, that the bioaccumulation of toxic 3,3′,4,4′,5-penta- and 2,3,3′,4,4′-pentachlorobiphenyls in carnivorous marine mammals is a cause for considerable concern.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">PCBs</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biphenyl</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Penta</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Bioaccumulation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Marine Mammal</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tanabe, Shinsuke</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ono, Mitsuhiro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tatsukawa, Ryo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Archives of environmental contamination and toxicology</subfield><subfield code="d">Springer-Verlag, 1973</subfield><subfield code="g">18(1989), 6 vom: Nov., Seite 850-857</subfield><subfield code="w">(DE-627)129397725</subfield><subfield code="w">(DE-600)185986-9</subfield><subfield code="w">(DE-576)01478100X</subfield><subfield code="x">0090-4341</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:18</subfield><subfield code="g">year:1989</subfield><subfield code="g">number:6</subfield><subfield code="g">month:11</subfield><subfield code="g">pages:850-857</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/BF01160300</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-UMW</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_130</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_154</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_252</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_601</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4103</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4219</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4277</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">18</subfield><subfield code="j">1989</subfield><subfield code="e">6</subfield><subfield code="c">11</subfield><subfield code="h">850-857</subfield></datafield></record></collection>
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