RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes
Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as refer...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Schmid, E. [verfasserIn] |
|---|
| Format: |
Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2003 |
|---|
| Schlagwörter: |
|---|
| Anmerkung: |
© Springer-Verlag 2003 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Radiation and environmental biophysics - Springer-Verlag, 1974, 42(2003), 2 vom: Juli, Seite 87-94 |
|---|---|
| Übergeordnetes Werk: |
volume:42 ; year:2003 ; number:2 ; month:07 ; pages:87-94 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00411-003-0200-0 |
|---|
| Katalog-ID: |
OLC2075415463 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC2075415463 | ||
| 003 | DE-627 | ||
| 005 | 20230402231317.0 | ||
| 007 | tu | ||
| 008 | 200820s2003 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00411-003-0200-0 |2 doi | |
| 035 | |a (DE-627)OLC2075415463 | ||
| 035 | |a (DE-He213)s00411-003-0200-0-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 570 |a 530 |q VZ |
| 084 | |a 12 |2 ssgn | ||
| 084 | |a BIODIV |q DE-30 |2 fid | ||
| 100 | 1 | |a Schmid, E. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| 264 | 1 | |c 2003 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © Springer-Verlag 2003 | ||
| 520 | |a Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. | ||
| 650 | 4 | |a Human Lymphocyte | |
| 650 | 4 | |a Neutron Energy | |
| 650 | 4 | |a Centric Ring | |
| 650 | 4 | |a Relative Biological Effectiveness | |
| 650 | 4 | |a Neutron Fluence | |
| 700 | 1 | |a Schlegel, D. |4 aut | |
| 700 | 1 | |a Guldbakke, S. |4 aut | |
| 700 | 1 | |a Kapsch, R.-P. |4 aut | |
| 700 | 1 | |a Regulla, D. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Radiation and environmental biophysics |d Springer-Verlag, 1974 |g 42(2003), 2 vom: Juli, Seite 87-94 |w (DE-627)129308528 |w (DE-600)124987-3 |w (DE-576)014507870 |x 0301-634X |7 nnns |
| 773 | 1 | 8 | |g volume:42 |g year:2003 |g number:2 |g month:07 |g pages:87-94 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/s00411-003-0200-0 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a FID-BIODIV | ||
| 912 | |a SSG-OLC-PHY | ||
| 912 | |a SSG-OPC-GGO | ||
| 912 | |a GBV_ILN_11 | ||
| 912 | |a GBV_ILN_21 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_2018 | ||
| 912 | |a GBV_ILN_4012 | ||
| 912 | |a GBV_ILN_4082 | ||
| 912 | |a GBV_ILN_4219 | ||
| 912 | |a GBV_ILN_4277 | ||
| 951 | |a AR | ||
| 952 | |d 42 |j 2003 |e 2 |c 07 |h 87-94 | ||
| author_variant |
e s es d s ds s g sg r p k rpk d r dr |
|---|---|
| matchkey_str |
article:0301634X:2003----::bonalmneegtcetostnrisf6e16efrnutoodc |
| hierarchy_sort_str |
2003 |
| publishDate |
2003 |
| allfields |
10.1007/s00411-003-0200-0 doi (DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p DE-627 ger DE-627 rakwb eng 570 530 VZ 12 ssgn BIODIV DE-30 fid Schmid, E. verfasserin aut RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes 2003 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2003 Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence Schlegel, D. aut Guldbakke, S. aut Kapsch, R.-P. aut Regulla, D. aut Enthalten in Radiation and environmental biophysics Springer-Verlag, 1974 42(2003), 2 vom: Juli, Seite 87-94 (DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 0301-634X nnns volume:42 year:2003 number:2 month:07 pages:87-94 https://doi.org/10.1007/s00411-003-0200-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 AR 42 2003 2 07 87-94 |
| spelling |
10.1007/s00411-003-0200-0 doi (DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p DE-627 ger DE-627 rakwb eng 570 530 VZ 12 ssgn BIODIV DE-30 fid Schmid, E. verfasserin aut RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes 2003 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2003 Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence Schlegel, D. aut Guldbakke, S. aut Kapsch, R.-P. aut Regulla, D. aut Enthalten in Radiation and environmental biophysics Springer-Verlag, 1974 42(2003), 2 vom: Juli, Seite 87-94 (DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 0301-634X nnns volume:42 year:2003 number:2 month:07 pages:87-94 https://doi.org/10.1007/s00411-003-0200-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 AR 42 2003 2 07 87-94 |
| allfields_unstemmed |
10.1007/s00411-003-0200-0 doi (DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p DE-627 ger DE-627 rakwb eng 570 530 VZ 12 ssgn BIODIV DE-30 fid Schmid, E. verfasserin aut RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes 2003 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2003 Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence Schlegel, D. aut Guldbakke, S. aut Kapsch, R.-P. aut Regulla, D. aut Enthalten in Radiation and environmental biophysics Springer-Verlag, 1974 42(2003), 2 vom: Juli, Seite 87-94 (DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 0301-634X nnns volume:42 year:2003 number:2 month:07 pages:87-94 https://doi.org/10.1007/s00411-003-0200-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 AR 42 2003 2 07 87-94 |
| allfieldsGer |
10.1007/s00411-003-0200-0 doi (DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p DE-627 ger DE-627 rakwb eng 570 530 VZ 12 ssgn BIODIV DE-30 fid Schmid, E. verfasserin aut RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes 2003 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2003 Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence Schlegel, D. aut Guldbakke, S. aut Kapsch, R.-P. aut Regulla, D. aut Enthalten in Radiation and environmental biophysics Springer-Verlag, 1974 42(2003), 2 vom: Juli, Seite 87-94 (DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 0301-634X nnns volume:42 year:2003 number:2 month:07 pages:87-94 https://doi.org/10.1007/s00411-003-0200-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 AR 42 2003 2 07 87-94 |
| allfieldsSound |
10.1007/s00411-003-0200-0 doi (DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p DE-627 ger DE-627 rakwb eng 570 530 VZ 12 ssgn BIODIV DE-30 fid Schmid, E. verfasserin aut RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes 2003 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 2003 Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence Schlegel, D. aut Guldbakke, S. aut Kapsch, R.-P. aut Regulla, D. aut Enthalten in Radiation and environmental biophysics Springer-Verlag, 1974 42(2003), 2 vom: Juli, Seite 87-94 (DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 0301-634X nnns volume:42 year:2003 number:2 month:07 pages:87-94 https://doi.org/10.1007/s00411-003-0200-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 AR 42 2003 2 07 87-94 |
| language |
English |
| source |
Enthalten in Radiation and environmental biophysics 42(2003), 2 vom: Juli, Seite 87-94 volume:42 year:2003 number:2 month:07 pages:87-94 |
| sourceStr |
Enthalten in Radiation and environmental biophysics 42(2003), 2 vom: Juli, Seite 87-94 volume:42 year:2003 number:2 month:07 pages:87-94 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence |
| dewey-raw |
570 |
| isfreeaccess_bool |
false |
| container_title |
Radiation and environmental biophysics |
| authorswithroles_txt_mv |
Schmid, E. @@aut@@ Schlegel, D. @@aut@@ Guldbakke, S. @@aut@@ Kapsch, R.-P. @@aut@@ Regulla, D. @@aut@@ |
| publishDateDaySort_date |
2003-07-01T00:00:00Z |
| hierarchy_top_id |
129308528 |
| dewey-sort |
3570 |
| id |
OLC2075415463 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2075415463</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230402231317.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2003 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00411-003-0200-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2075415463</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00411-003-0200-0-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">12</subfield><subfield code="2">ssgn</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">BIODIV</subfield><subfield code="q">DE-30</subfield><subfield code="2">fid</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Schmid, E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 2003</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human Lymphocyte</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neutron Energy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Centric Ring</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Relative Biological Effectiveness</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neutron Fluence</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schlegel, D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Guldbakke, S.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kapsch, R.-P.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Regulla, D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Radiation and environmental biophysics</subfield><subfield code="d">Springer-Verlag, 1974</subfield><subfield code="g">42(2003), 2 vom: Juli, Seite 87-94</subfield><subfield code="w">(DE-627)129308528</subfield><subfield code="w">(DE-600)124987-3</subfield><subfield code="w">(DE-576)014507870</subfield><subfield code="x">0301-634X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:42</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:2</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:87-94</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00411-003-0200-0</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">FID-BIODIV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OPC-GGO</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4082</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4219</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4277</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">42</subfield><subfield code="j">2003</subfield><subfield code="e">2</subfield><subfield code="c">07</subfield><subfield code="h">87-94</subfield></datafield></record></collection>
|
| author |
Schmid, E. |
| spellingShingle |
Schmid, E. ddc 570 ssgn 12 fid BIODIV misc Human Lymphocyte misc Neutron Energy misc Centric Ring misc Relative Biological Effectiveness misc Neutron Fluence RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| authorStr |
Schmid, E. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)129308528 |
| format |
Article |
| dewey-ones |
570 - Life sciences; biology 530 - Physics |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut |
| collection |
OLC |
| remote_str |
false |
| illustrated |
Not Illustrated |
| issn |
0301-634X |
| topic_title |
570 530 VZ 12 ssgn BIODIV DE-30 fid RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes Human Lymphocyte Neutron Energy Centric Ring Relative Biological Effectiveness Neutron Fluence |
| topic |
ddc 570 ssgn 12 fid BIODIV misc Human Lymphocyte misc Neutron Energy misc Centric Ring misc Relative Biological Effectiveness misc Neutron Fluence |
| topic_unstemmed |
ddc 570 ssgn 12 fid BIODIV misc Human Lymphocyte misc Neutron Energy misc Centric Ring misc Relative Biological Effectiveness misc Neutron Fluence |
| topic_browse |
ddc 570 ssgn 12 fid BIODIV misc Human Lymphocyte misc Neutron Energy misc Centric Ring misc Relative Biological Effectiveness misc Neutron Fluence |
| format_facet |
Aufsätze Gedruckte Aufsätze |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
nc |
| hierarchy_parent_title |
Radiation and environmental biophysics |
| hierarchy_parent_id |
129308528 |
| dewey-tens |
570 - Life sciences; biology 530 - Physics |
| hierarchy_top_title |
Radiation and environmental biophysics |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)129308528 (DE-600)124987-3 (DE-576)014507870 |
| title |
RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| ctrlnum |
(DE-627)OLC2075415463 (DE-He213)s00411-003-0200-0-p |
| title_full |
RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| author_sort |
Schmid, E. |
| journal |
Radiation and environmental biophysics |
| journalStr |
Radiation and environmental biophysics |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science |
| recordtype |
marc |
| publishDateSort |
2003 |
| contenttype_str_mv |
txt |
| container_start_page |
87 |
| author_browse |
Schmid, E. Schlegel, D. Guldbakke, S. Kapsch, R.-P. Regulla, D. |
| container_volume |
42 |
| class |
570 530 VZ 12 ssgn BIODIV DE-30 fid |
| format_se |
Aufsätze |
| author-letter |
Schmid, E. |
| doi_str_mv |
10.1007/s00411-003-0200-0 |
| dewey-full |
570 530 |
| title_sort |
rbe of nearly monoenergetic neutrons at energies of 36 kev–14.6 mev for induction of dicentrics in human lymphocytes |
| title_auth |
RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| abstract |
Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. © Springer-Verlag 2003 |
| abstractGer |
Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. © Springer-Verlag 2003 |
| abstract_unstemmed |
Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy. © Springer-Verlag 2003 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OPC-GGO GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_40 GBV_ILN_70 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4082 GBV_ILN_4219 GBV_ILN_4277 |
| container_issue |
2 |
| title_short |
RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes |
| url |
https://doi.org/10.1007/s00411-003-0200-0 |
| remote_bool |
false |
| author2 |
Schlegel, D. Guldbakke, S. Kapsch, R.-P. Regulla, D. |
| author2Str |
Schlegel, D. Guldbakke, S. Kapsch, R.-P. Regulla, D. |
| ppnlink |
129308528 |
| mediatype_str_mv |
n |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00411-003-0200-0 |
| up_date |
2024-07-04T01:16:46.229Z |
| _version_ |
1803609237073428480 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">OLC2075415463</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230402231317.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">200820s2003 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00411-003-0200-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC2075415463</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)s00411-003-0200-0-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">12</subfield><subfield code="2">ssgn</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">BIODIV</subfield><subfield code="q">DE-30</subfield><subfield code="2">fid</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Schmid, E.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">RBE of nearly monoenergetic neutrons at energies of 36 keV–14.6 MeV for induction of dicentrics in human lymphocytes</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 2003</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We examined the induction of dicentric chromosomes in human lymphocytes irradiated in vitro with nearly monoenergetic neutrons at energies in the range of 36 keV–15.0 MeV. For the assessment of the relative biological effectiveness (RBE) both 220 kV x-rays and 60Co γ-rays were used as reference radiations. To avoid potential confounding factors that would influence the outcome of the experiments, only blood from one individual was used. The neutron RBE culture conditions ensured that the chromosome analysis could be performed exclusively in metaphases of the first cell cycle in vitro. For the reference radiation of 220 kV x-rays, the values of $ RBE_{M} $ were found to increase from 16.6 ($ E_{n} $=36 keV) to the maximum value of 23.4 ($ E_{n} $=385 keV). For 60Co γ-rays utilized as the reference radiation, the corresponding $ RBE_{M} $ values were found to be higher by a factor of 4. These results agree well with the previously published large data sets of three laboratories on dose-response relationships for dicentrics or dicentrics plus centric rings. They show a similar dependence of RBE on neutron energy.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Human Lymphocyte</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neutron Energy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Centric Ring</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Relative Biological Effectiveness</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neutron Fluence</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Schlegel, D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Guldbakke, S.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kapsch, R.-P.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Regulla, D.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Radiation and environmental biophysics</subfield><subfield code="d">Springer-Verlag, 1974</subfield><subfield code="g">42(2003), 2 vom: Juli, Seite 87-94</subfield><subfield code="w">(DE-627)129308528</subfield><subfield code="w">(DE-600)124987-3</subfield><subfield code="w">(DE-576)014507870</subfield><subfield code="x">0301-634X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:42</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:2</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:87-94</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/s00411-003-0200-0</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">FID-BIODIV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHY</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OPC-GGO</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4082</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4219</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4277</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">42</subfield><subfield code="j">2003</subfield><subfield code="e">2</subfield><subfield code="c">07</subfield><subfield code="h">87-94</subfield></datafield></record></collection>
|
| score |
7.399867 |