Antidiuretic activities of substance P and its analogs

Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapep...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ukai, M. [verfasserIn] Nagase, T. Hirohashi, M. Yanaihara, N.

Format:	Artikel
Sprache:	Englisch

Erschienen:	1981

Schlagwörter:	Peptide Nucleoside Antidiuretic Activity Hypotensive Potency

Anmerkung:	© Birkhäuser Verlag 1981

Übergeordnetes Werk:	Enthalten in: Experientia - Birkhäuser-Verlag, 1945, 37(1981), 5 vom: Mai, Seite 521-523
Übergeordnetes Werk:	volume:37 ; year:1981 ; number:5 ; month:05 ; pages:521-523

Links:	Volltext

DOI / URN:	10.1007/BF01986174

Katalog-ID:	OLC2080700502

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Indexfelder

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allfields	10.1007/BF01986174 doi (DE-627)OLC2080700502 (DE-He213)BF01986174-p DE-627 ger DE-627 rakwb eng 500 610 VZ Ukai, M. verfasserin aut Antidiuretic activities of substance P and its analogs 1981 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Birkhäuser Verlag 1981 Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. Peptide Nucleoside Antidiuretic Activity Hypotensive Potency Nagase, T. aut Hirohashi, M. aut Yanaihara, N. aut Enthalten in Experientia Birkhäuser-Verlag, 1945 37(1981), 5 vom: Mai, Seite 521-523 (DE-627)129070955 (DE-600)1972-0 (DE-576)014402912 0014-4754 nnns volume:37 year:1981 number:5 month:05 pages:521-523 https://doi.org/10.1007/BF01986174 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_31 GBV_ILN_40 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_105 GBV_ILN_171 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2010 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2221 GBV_ILN_2360 GBV_ILN_4012 GBV_ILN_4027 GBV_ILN_4028 GBV_ILN_4035 GBV_ILN_4046 GBV_ILN_4082 GBV_ILN_4103 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4319 GBV_ILN_4323 AR 37 1981 5 05 521-523
spelling	10.1007/BF01986174 doi (DE-627)OLC2080700502 (DE-He213)BF01986174-p DE-627 ger DE-627 rakwb eng 500 610 VZ Ukai, M. verfasserin aut Antidiuretic activities of substance P and its analogs 1981 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Birkhäuser Verlag 1981 Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. Peptide Nucleoside Antidiuretic Activity Hypotensive Potency Nagase, T. aut Hirohashi, M. aut Yanaihara, N. aut Enthalten in Experientia Birkhäuser-Verlag, 1945 37(1981), 5 vom: Mai, Seite 521-523 (DE-627)129070955 (DE-600)1972-0 (DE-576)014402912 0014-4754 nnns volume:37 year:1981 number:5 month:05 pages:521-523 https://doi.org/10.1007/BF01986174 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_31 GBV_ILN_40 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_105 GBV_ILN_171 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2010 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2221 GBV_ILN_2360 GBV_ILN_4012 GBV_ILN_4027 GBV_ILN_4028 GBV_ILN_4035 GBV_ILN_4046 GBV_ILN_4082 GBV_ILN_4103 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4319 GBV_ILN_4323 AR 37 1981 5 05 521-523
allfields_unstemmed	10.1007/BF01986174 doi (DE-627)OLC2080700502 (DE-He213)BF01986174-p DE-627 ger DE-627 rakwb eng 500 610 VZ Ukai, M. verfasserin aut Antidiuretic activities of substance P and its analogs 1981 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Birkhäuser Verlag 1981 Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. Peptide Nucleoside Antidiuretic Activity Hypotensive Potency Nagase, T. aut Hirohashi, M. aut Yanaihara, N. aut Enthalten in Experientia Birkhäuser-Verlag, 1945 37(1981), 5 vom: Mai, Seite 521-523 (DE-627)129070955 (DE-600)1972-0 (DE-576)014402912 0014-4754 nnns volume:37 year:1981 number:5 month:05 pages:521-523 https://doi.org/10.1007/BF01986174 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_31 GBV_ILN_40 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_105 GBV_ILN_171 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2010 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2221 GBV_ILN_2360 GBV_ILN_4012 GBV_ILN_4027 GBV_ILN_4028 GBV_ILN_4035 GBV_ILN_4046 GBV_ILN_4082 GBV_ILN_4103 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4319 GBV_ILN_4323 AR 37 1981 5 05 521-523
allfieldsGer	10.1007/BF01986174 doi (DE-627)OLC2080700502 (DE-He213)BF01986174-p DE-627 ger DE-627 rakwb eng 500 610 VZ Ukai, M. verfasserin aut Antidiuretic activities of substance P and its analogs 1981 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Birkhäuser Verlag 1981 Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. Peptide Nucleoside Antidiuretic Activity Hypotensive Potency Nagase, T. aut Hirohashi, M. aut Yanaihara, N. aut Enthalten in Experientia Birkhäuser-Verlag, 1945 37(1981), 5 vom: Mai, Seite 521-523 (DE-627)129070955 (DE-600)1972-0 (DE-576)014402912 0014-4754 nnns volume:37 year:1981 number:5 month:05 pages:521-523 https://doi.org/10.1007/BF01986174 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_31 GBV_ILN_40 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_105 GBV_ILN_171 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2010 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2221 GBV_ILN_2360 GBV_ILN_4012 GBV_ILN_4027 GBV_ILN_4028 GBV_ILN_4035 GBV_ILN_4046 GBV_ILN_4082 GBV_ILN_4103 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4319 GBV_ILN_4323 AR 37 1981 5 05 521-523
allfieldsSound	10.1007/BF01986174 doi (DE-627)OLC2080700502 (DE-He213)BF01986174-p DE-627 ger DE-627 rakwb eng 500 610 VZ Ukai, M. verfasserin aut Antidiuretic activities of substance P and its analogs 1981 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Birkhäuser Verlag 1981 Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. Peptide Nucleoside Antidiuretic Activity Hypotensive Potency Nagase, T. aut Hirohashi, M. aut Yanaihara, N. aut Enthalten in Experientia Birkhäuser-Verlag, 1945 37(1981), 5 vom: Mai, Seite 521-523 (DE-627)129070955 (DE-600)1972-0 (DE-576)014402912 0014-4754 nnns volume:37 year:1981 number:5 month:05 pages:521-523 https://doi.org/10.1007/BF01986174 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-MAT GBV_ILN_11 GBV_ILN_21 GBV_ILN_22 GBV_ILN_31 GBV_ILN_40 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_105 GBV_ILN_171 GBV_ILN_211 GBV_ILN_252 GBV_ILN_259 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2010 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2021 GBV_ILN_2221 GBV_ILN_2360 GBV_ILN_4012 GBV_ILN_4027 GBV_ILN_4028 GBV_ILN_4035 GBV_ILN_4046 GBV_ILN_4082 GBV_ILN_4103 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4219 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4314 GBV_ILN_4317 GBV_ILN_4319 GBV_ILN_4323 AR 37 1981 5 05 521-523
language	English
source	Enthalten in Experientia 37(1981), 5 vom: Mai, Seite 521-523 volume:37 year:1981 number:5 month:05 pages:521-523
sourceStr	Enthalten in Experientia 37(1981), 5 vom: Mai, Seite 521-523 volume:37 year:1981 number:5 month:05 pages:521-523
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Peptide Nucleoside Antidiuretic Activity Hypotensive Potency
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container_title	Experientia
authorswithroles_txt_mv	Ukai, M. @@aut@@ Nagase, T. @@aut@@ Hirohashi, M. @@aut@@ Yanaihara, N. @@aut@@
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spellingShingle	Ukai, M. ddc 500 misc Peptide misc Nucleoside misc Antidiuretic Activity misc Hypotensive Potency Antidiuretic activities of substance P and its analogs
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title	Antidiuretic activities of substance P and its analogs
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title_full	Antidiuretic activities of substance P and its analogs
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author_browse	Ukai, M. Nagase, T. Hirohashi, M. Yanaihara, N.
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title_sort	antidiuretic activities of substance p and its analogs
title_auth	Antidiuretic activities of substance P and its analogs
abstract	Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. © Birkhäuser Verlag 1981
abstractGer	Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. © Birkhäuser Verlag 1981
abstract_unstemmed	Summary Substance P (SP) and analogs, including 5 nucleoside (ARA or HRA)-peptides, were examined for antidiuretic activity in ethanolized rats. The activity was potent in the analogs embodying the C-terminal hexapeptide, weak in the nucleoside-pentapeptide, and negligible in the nucleoside-tetrapeptide. In addition, the activity was increased by acylation of the hexapeptide. The antidiuretic potencies were also compared with the hypotensive potencies. © Birkhäuser Verlag 1981
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title_short	Antidiuretic activities of substance P and its analogs
url	https://doi.org/10.1007/BF01986174
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author2	Nagase, T. Hirohashi, M. Yanaihara, N.
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up_date	2024-07-04T04:28:02.948Z
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