Synthesis, characterisation and ferric ion complexation studies of chelating probes for oxidative stress
Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Fisher, Anna E. O. [verfasserIn] |
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| Format: |
Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2004 |
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| Schlagwörter: |
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| Anmerkung: |
© Kluwer Academic Publishers 2004 |
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| Übergeordnetes Werk: |
Enthalten in: Transition metal chemistry - Kluwer Academic Publishers, 1975, 29(2004), 3 vom: Apr., Seite 315-319 |
|---|---|
| Übergeordnetes Werk: |
volume:29 ; year:2004 ; number:3 ; month:04 ; pages:315-319 |
| Links: |
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| DOI / URN: |
10.1023/B:TMCH.0000020375.95715.6f |
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| 520 | |a Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. Over the physiological pH range a favoured one to one complex exists. | ||
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10.1023/B:TMCH.0000020375.95715.6f doi (DE-627)OLC2084026652 (DE-He213)B:TMCH.0000020375.95715.6f-p DE-627 ger DE-627 rakwb eng 660 VZ Fisher, Anna E. O. verfasserin aut Synthesis, characterisation and ferric ion complexation studies of chelating probes for oxidative stress 2004 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Kluwer Academic Publishers 2004 Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. Over the physiological pH range a favoured one to one complex exists. Oxidative Stress Electronic Absorption Species Distribution Aromatic Amino Acid Nitrogen Species Naughton, Declan P. aut Enthalten in Transition metal chemistry Kluwer Academic Publishers, 1975 29(2004), 3 vom: Apr., Seite 315-319 (DE-627)129605417 (DE-600)242084-3 (DE-576)015099652 0340-4285 nnns volume:29 year:2004 number:3 month:04 pages:315-319 https://doi.org/10.1023/B:TMCH.0000020375.95715.6f lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_21 GBV_ILN_24 GBV_ILN_70 GBV_ILN_4012 GBV_ILN_4125 GBV_ILN_4323 AR 29 2004 3 04 315-319 |
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Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. Over the physiological pH range a favoured one to one complex exists. © Kluwer Academic Publishers 2004 |
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Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. Over the physiological pH range a favoured one to one complex exists. © Kluwer Academic Publishers 2004 |
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Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. Over the physiological pH range a favoured one to one complex exists. © Kluwer Academic Publishers 2004 |
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O.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Synthesis, characterisation and ferric ion complexation studies of chelating probes for oxidative stress</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2004</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Kluwer Academic Publishers 2004</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The ferric ion binding characteristics of a novel chelating probe for detecting ‘reactive oxygen and nitrogen species’ are reported. The probe comprises a polyaminocarboxylic acid chelator (EDTA) conjugated with aromatic amino acids. The probe (i) complexes redox-active and non-redox active metal ions and (ii) differentiates between different reactive oxygen/nitrogen species based upon the reaction products with same. The ferric ion binding characteristics were measured using species distribution and electronic absorption spectroscopic investigations. 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