Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor
Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hwang, Y. B. [verfasserIn] |
|---|
| Format: |
Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
1988 |
|---|
| Schlagwörter: |
|---|
| Anmerkung: |
© Springer-Verlag 1988 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Bioprocess engineering - Springer-Verlag, 1986, 3(1988), 4 vom: Dez., Seite 159-163 |
|---|---|
| Übergeordnetes Werk: |
volume:3 ; year:1988 ; number:4 ; month:12 ; pages:159-163 |
| Links: |
|---|
| DOI / URN: |
10.1007/BF00379651 |
|---|
| Katalog-ID: |
OLC210659500X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | OLC210659500X | ||
| 003 | DE-627 | ||
| 005 | 20230403073119.0 | ||
| 007 | tu | ||
| 008 | 230403s1988 xx ||||| 00| ||eng c | ||
| 024 | 7 | |a 10.1007/BF00379651 |2 doi | |
| 035 | |a (DE-627)OLC210659500X | ||
| 035 | |a (DE-He213)BF00379651-p | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 570 |a 690 |a 540 |q VZ |
| 084 | |a 12 |2 ssgn | ||
| 100 | 1 | |a Hwang, Y. B. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| 264 | 1 | |c 1988 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a © Springer-Verlag 1988 | ||
| 520 | |a Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. | ||
| 650 | 4 | |a Hollow Fiber | |
| 650 | 4 | |a High Density Cell | |
| 650 | 4 | |a Volumetric Productivity | |
| 650 | 4 | |a Fiber Membrane | |
| 650 | 4 | |a Hollow Fiber Membrane | |
| 700 | 1 | |a Chung, B. H. |4 aut | |
| 700 | 1 | |a Chang, H. N. |4 aut | |
| 700 | 1 | |a Han, M. H. |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Bioprocess engineering |d Springer-Verlag, 1986 |g 3(1988), 4 vom: Dez., Seite 159-163 |w (DE-627)129208922 |w (DE-600)55154-5 |w (DE-576)01445761X |x 0178-515X |7 nnns |
| 773 | 1 | 8 | |g volume:3 |g year:1988 |g number:4 |g month:12 |g pages:159-163 |
| 856 | 4 | 1 | |u https://doi.org/10.1007/BF00379651 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_OLC | ||
| 912 | |a SSG-OLC-UMW | ||
| 912 | |a SSG-OLC-ARC | ||
| 912 | |a SSG-OLC-TEC | ||
| 912 | |a SSG-OLC-CHE | ||
| 912 | |a GBV_ILN_11 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_2004 | ||
| 912 | |a GBV_ILN_2006 | ||
| 912 | |a GBV_ILN_2018 | ||
| 912 | |a GBV_ILN_4046 | ||
| 912 | |a GBV_ILN_4103 | ||
| 912 | |a GBV_ILN_4307 | ||
| 912 | |a GBV_ILN_4310 | ||
| 912 | |a GBV_ILN_4323 | ||
| 951 | |a AR | ||
| 952 | |d 3 |j 1988 |e 4 |c 12 |h 159-163 | ||
| author_variant |
y b h yb ybh b h c bh bhc h n c hn hnc m h h mh mhh |
|---|---|
| matchkey_str |
article:0178515X:1988----::ilgclovrinfiayibyieuioapelimblzdnd |
| hierarchy_sort_str |
1988 |
| publishDate |
1988 |
| allfields |
10.1007/BF00379651 doi (DE-627)OLC210659500X (DE-He213)BF00379651-p DE-627 ger DE-627 rakwb eng 570 690 540 VZ 12 ssgn Hwang, Y. B. verfasserin aut Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor 1988 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 1988 Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane Chung, B. H. aut Chang, H. N. aut Han, M. H. aut Enthalten in Bioprocess engineering Springer-Verlag, 1986 3(1988), 4 vom: Dez., Seite 159-163 (DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X 0178-515X nnns volume:3 year:1988 number:4 month:12 pages:159-163 https://doi.org/10.1007/BF00379651 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 AR 3 1988 4 12 159-163 |
| spelling |
10.1007/BF00379651 doi (DE-627)OLC210659500X (DE-He213)BF00379651-p DE-627 ger DE-627 rakwb eng 570 690 540 VZ 12 ssgn Hwang, Y. B. verfasserin aut Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor 1988 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 1988 Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane Chung, B. H. aut Chang, H. N. aut Han, M. H. aut Enthalten in Bioprocess engineering Springer-Verlag, 1986 3(1988), 4 vom: Dez., Seite 159-163 (DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X 0178-515X nnns volume:3 year:1988 number:4 month:12 pages:159-163 https://doi.org/10.1007/BF00379651 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 AR 3 1988 4 12 159-163 |
| allfields_unstemmed |
10.1007/BF00379651 doi (DE-627)OLC210659500X (DE-He213)BF00379651-p DE-627 ger DE-627 rakwb eng 570 690 540 VZ 12 ssgn Hwang, Y. B. verfasserin aut Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor 1988 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 1988 Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane Chung, B. H. aut Chang, H. N. aut Han, M. H. aut Enthalten in Bioprocess engineering Springer-Verlag, 1986 3(1988), 4 vom: Dez., Seite 159-163 (DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X 0178-515X nnns volume:3 year:1988 number:4 month:12 pages:159-163 https://doi.org/10.1007/BF00379651 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 AR 3 1988 4 12 159-163 |
| allfieldsGer |
10.1007/BF00379651 doi (DE-627)OLC210659500X (DE-He213)BF00379651-p DE-627 ger DE-627 rakwb eng 570 690 540 VZ 12 ssgn Hwang, Y. B. verfasserin aut Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor 1988 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 1988 Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane Chung, B. H. aut Chang, H. N. aut Han, M. H. aut Enthalten in Bioprocess engineering Springer-Verlag, 1986 3(1988), 4 vom: Dez., Seite 159-163 (DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X 0178-515X nnns volume:3 year:1988 number:4 month:12 pages:159-163 https://doi.org/10.1007/BF00379651 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 AR 3 1988 4 12 159-163 |
| allfieldsSound |
10.1007/BF00379651 doi (DE-627)OLC210659500X (DE-He213)BF00379651-p DE-627 ger DE-627 rakwb eng 570 690 540 VZ 12 ssgn Hwang, Y. B. verfasserin aut Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor 1988 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier © Springer-Verlag 1988 Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane Chung, B. H. aut Chang, H. N. aut Han, M. H. aut Enthalten in Bioprocess engineering Springer-Verlag, 1986 3(1988), 4 vom: Dez., Seite 159-163 (DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X 0178-515X nnns volume:3 year:1988 number:4 month:12 pages:159-163 https://doi.org/10.1007/BF00379651 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 AR 3 1988 4 12 159-163 |
| language |
English |
| source |
Enthalten in Bioprocess engineering 3(1988), 4 vom: Dez., Seite 159-163 volume:3 year:1988 number:4 month:12 pages:159-163 |
| sourceStr |
Enthalten in Bioprocess engineering 3(1988), 4 vom: Dez., Seite 159-163 volume:3 year:1988 number:4 month:12 pages:159-163 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane |
| dewey-raw |
570 |
| isfreeaccess_bool |
false |
| container_title |
Bioprocess engineering |
| authorswithroles_txt_mv |
Hwang, Y. B. @@aut@@ Chung, B. H. @@aut@@ Chang, H. N. @@aut@@ Han, M. H. @@aut@@ |
| publishDateDaySort_date |
1988-12-01T00:00:00Z |
| hierarchy_top_id |
129208922 |
| dewey-sort |
3570 |
| id |
OLC210659500X |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">OLC210659500X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230403073119.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">230403s1988 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF00379651</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC210659500X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)BF00379651-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">690</subfield><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">12</subfield><subfield code="2">ssgn</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hwang, Y. B.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1988</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 1988</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hollow Fiber</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">High Density Cell</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Volumetric Productivity</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Fiber Membrane</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hollow Fiber Membrane</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chung, B. H.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, H. N.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Han, M. H.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Bioprocess engineering</subfield><subfield code="d">Springer-Verlag, 1986</subfield><subfield code="g">3(1988), 4 vom: Dez., Seite 159-163</subfield><subfield code="w">(DE-627)129208922</subfield><subfield code="w">(DE-600)55154-5</subfield><subfield code="w">(DE-576)01445761X</subfield><subfield code="x">0178-515X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:3</subfield><subfield code="g">year:1988</subfield><subfield code="g">number:4</subfield><subfield code="g">month:12</subfield><subfield code="g">pages:159-163</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/BF00379651</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-UMW</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-ARC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-TEC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-CHE</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4046</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4103</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4310</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">3</subfield><subfield code="j">1988</subfield><subfield code="e">4</subfield><subfield code="c">12</subfield><subfield code="h">159-163</subfield></datafield></record></collection>
|
| author |
Hwang, Y. B. |
| spellingShingle |
Hwang, Y. B. ddc 570 ssgn 12 misc Hollow Fiber misc High Density Cell misc Volumetric Productivity misc Fiber Membrane misc Hollow Fiber Membrane Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| authorStr |
Hwang, Y. B. |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)129208922 |
| format |
Article |
| dewey-ones |
570 - Life sciences; biology 690 - Buildings 540 - Chemistry & allied sciences |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut |
| collection |
OLC |
| remote_str |
false |
| illustrated |
Not Illustrated |
| issn |
0178-515X |
| topic_title |
570 690 540 VZ 12 ssgn Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor Hollow Fiber High Density Cell Volumetric Productivity Fiber Membrane Hollow Fiber Membrane |
| topic |
ddc 570 ssgn 12 misc Hollow Fiber misc High Density Cell misc Volumetric Productivity misc Fiber Membrane misc Hollow Fiber Membrane |
| topic_unstemmed |
ddc 570 ssgn 12 misc Hollow Fiber misc High Density Cell misc Volumetric Productivity misc Fiber Membrane misc Hollow Fiber Membrane |
| topic_browse |
ddc 570 ssgn 12 misc Hollow Fiber misc High Density Cell misc Volumetric Productivity misc Fiber Membrane misc Hollow Fiber Membrane |
| format_facet |
Aufsätze Gedruckte Aufsätze |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
nc |
| hierarchy_parent_title |
Bioprocess engineering |
| hierarchy_parent_id |
129208922 |
| dewey-tens |
570 - Life sciences; biology 690 - Building & construction 540 - Chemistry |
| hierarchy_top_title |
Bioprocess engineering |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)129208922 (DE-600)55154-5 (DE-576)01445761X |
| title |
Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| ctrlnum |
(DE-627)OLC210659500X (DE-He213)BF00379651-p |
| title_full |
Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| author_sort |
Hwang, Y. B. |
| journal |
Bioprocess engineering |
| journalStr |
Bioprocess engineering |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science 600 - Technology |
| recordtype |
marc |
| publishDateSort |
1988 |
| contenttype_str_mv |
txt |
| container_start_page |
159 |
| author_browse |
Hwang, Y. B. Chung, B. H. Chang, H. N. Han, M. H. |
| container_volume |
3 |
| class |
570 690 540 VZ 12 ssgn |
| format_se |
Aufsätze |
| author-letter |
Hwang, Y. B. |
| doi_str_mv |
10.1007/BF00379651 |
| dewey-full |
570 690 540 |
| title_sort |
biological conversion of rifamycin b by live humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| title_auth |
Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| abstract |
Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. © Springer-Verlag 1988 |
| abstractGer |
Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. © Springer-Verlag 1988 |
| abstract_unstemmed |
Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h. © Springer-Verlag 1988 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_OLC SSG-OLC-UMW SSG-OLC-ARC SSG-OLC-TEC SSG-OLC-CHE GBV_ILN_11 GBV_ILN_23 GBV_ILN_40 GBV_ILN_65 GBV_ILN_70 GBV_ILN_2004 GBV_ILN_2006 GBV_ILN_2018 GBV_ILN_4046 GBV_ILN_4103 GBV_ILN_4307 GBV_ILN_4310 GBV_ILN_4323 |
| container_issue |
4 |
| title_short |
Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor |
| url |
https://doi.org/10.1007/BF00379651 |
| remote_bool |
false |
| author2 |
Chung, B. H. Chang, H. N. Han, M. H. |
| author2Str |
Chung, B. H. Chang, H. N. Han, M. H. |
| ppnlink |
129208922 |
| mediatype_str_mv |
n |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/BF00379651 |
| up_date |
2024-07-04T07:02:55.271Z |
| _version_ |
1803631014986121216 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">OLC210659500X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230403073119.0</controlfield><controlfield tag="007">tu</controlfield><controlfield tag="008">230403s1988 xx ||||| 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/BF00379651</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)OLC210659500X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-He213)BF00379651-p</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">690</subfield><subfield code="a">540</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">12</subfield><subfield code="2">ssgn</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hwang, Y. B.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1988</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">ohne Hilfsmittel zu benutzen</subfield><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Band</subfield><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 1988</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The biological transformation from rifamycin B to rifamycin S was carried out with the live whole cells of Humicola sp., ATCC 20620, immobilized in a dual hollow fiber bioreactor (DHFBR). Humicola sp., inoculated in the DHFBR, proliferated successfully to a high density cell mass within the space between an outer silicone tubing and three inner polypropylene hollow fiber membranes. In order to control the cell growth a nitrogen deficient medium was fed. Conversion of rifamycin B continued for more than 30 d, whereas that of immobilized rifamycin B oxidase lasted only for 3 d in comparable conditions. In the DHFBR the volumetric productivity of rifamycin S was 0.65–1.03 mmol/($ dm^{3} $ · h) with 60% conversion, while that in the rotating packed disk reactor was 0.27 mmol/($ dm^{3} $ · h) with 40% conversion at a residence time of 0.5–1.5 h.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hollow Fiber</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">High Density Cell</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Volumetric Productivity</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Fiber Membrane</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hollow Fiber Membrane</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chung, B. H.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chang, H. N.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Han, M. H.</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Bioprocess engineering</subfield><subfield code="d">Springer-Verlag, 1986</subfield><subfield code="g">3(1988), 4 vom: Dez., Seite 159-163</subfield><subfield code="w">(DE-627)129208922</subfield><subfield code="w">(DE-600)55154-5</subfield><subfield code="w">(DE-576)01445761X</subfield><subfield code="x">0178-515X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:3</subfield><subfield code="g">year:1988</subfield><subfield code="g">number:4</subfield><subfield code="g">month:12</subfield><subfield code="g">pages:159-163</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">https://doi.org/10.1007/BF00379651</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_OLC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-UMW</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-ARC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-TEC</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-CHE</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_11</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4046</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4103</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4310</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">3</subfield><subfield code="j">1988</subfield><subfield code="e">4</subfield><subfield code="c">12</subfield><subfield code="h">159-163</subfield></datafield></record></collection>
|
| score |
7.3987436 |