Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11
Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data...
Ausführliche Beschreibung
Autor*in: |
Chen, Ziming [verfasserIn] |
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Format: |
Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Anmerkung: |
©2017 Walter de Gruyter GmbH, Berlin/Boston |
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Übergeordnetes Werk: |
Enthalten in: Zeitschrift für Naturforschung. C, Biosciences - De Gruyter, 1973, 72(2016), 3-4 vom: 04. Okt., Seite 129-132 |
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Übergeordnetes Werk: |
volume:72 ; year:2016 ; number:3-4 ; day:04 ; month:10 ; pages:129-132 |
Links: |
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DOI / URN: |
10.1515/znc-2016-0122 |
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Katalog-ID: |
OLC214037231X |
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10.1515/znc-2016-0122 doi (DE-627)OLC214037231X (DE-B1597)znc-2016-0122-p DE-627 ger DE-627 rakwb eng 500 VZ 570 VZ 12 ssgn BIODIV DE-30 fid Chen, Ziming verfasserin aut Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier ©2017 Walter de Gruyter GmbH, Berlin/Boston Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. Chen, Yuchan aut Huang, Hongbo aut Yang, Hongyan aut Zhang, Weimin aut Sun, Yulin aut Wen, Jing aut Enthalten in Zeitschrift für Naturforschung. C, Biosciences De Gruyter, 1973 72(2016), 3-4 vom: 04. Okt., Seite 129-132 (DE-627)129307394 (DE-600)124636-7 (DE-576)014504936 0939-5075 nnns volume:72 year:2016 number:3-4 day:04 month:10 pages:129-132 https://doi.org/10.1515/znc-2016-0122 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR GBV_ILN_70 GBV_ILN_120 GBV_ILN_121 GBV_ILN_252 GBV_ILN_2015 GBV_ILN_2237 GBV_ILN_4012 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4320 AR 72 2016 3-4 04 10 129-132 |
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10.1515/znc-2016-0122 doi (DE-627)OLC214037231X (DE-B1597)znc-2016-0122-p DE-627 ger DE-627 rakwb eng 500 VZ 570 VZ 12 ssgn BIODIV DE-30 fid Chen, Ziming verfasserin aut Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier ©2017 Walter de Gruyter GmbH, Berlin/Boston Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. Chen, Yuchan aut Huang, Hongbo aut Yang, Hongyan aut Zhang, Weimin aut Sun, Yulin aut Wen, Jing aut Enthalten in Zeitschrift für Naturforschung. C, Biosciences De Gruyter, 1973 72(2016), 3-4 vom: 04. Okt., Seite 129-132 (DE-627)129307394 (DE-600)124636-7 (DE-576)014504936 0939-5075 nnns volume:72 year:2016 number:3-4 day:04 month:10 pages:129-132 https://doi.org/10.1515/znc-2016-0122 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR GBV_ILN_70 GBV_ILN_120 GBV_ILN_121 GBV_ILN_252 GBV_ILN_2015 GBV_ILN_2237 GBV_ILN_4012 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4320 AR 72 2016 3-4 04 10 129-132 |
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10.1515/znc-2016-0122 doi (DE-627)OLC214037231X (DE-B1597)znc-2016-0122-p DE-627 ger DE-627 rakwb eng 500 VZ 570 VZ 12 ssgn BIODIV DE-30 fid Chen, Ziming verfasserin aut Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier ©2017 Walter de Gruyter GmbH, Berlin/Boston Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. Chen, Yuchan aut Huang, Hongbo aut Yang, Hongyan aut Zhang, Weimin aut Sun, Yulin aut Wen, Jing aut Enthalten in Zeitschrift für Naturforschung. C, Biosciences De Gruyter, 1973 72(2016), 3-4 vom: 04. Okt., Seite 129-132 (DE-627)129307394 (DE-600)124636-7 (DE-576)014504936 0939-5075 nnns volume:72 year:2016 number:3-4 day:04 month:10 pages:129-132 https://doi.org/10.1515/znc-2016-0122 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR GBV_ILN_70 GBV_ILN_120 GBV_ILN_121 GBV_ILN_252 GBV_ILN_2015 GBV_ILN_2237 GBV_ILN_4012 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4320 AR 72 2016 3-4 04 10 129-132 |
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10.1515/znc-2016-0122 doi (DE-627)OLC214037231X (DE-B1597)znc-2016-0122-p DE-627 ger DE-627 rakwb eng 500 VZ 570 VZ 12 ssgn BIODIV DE-30 fid Chen, Ziming verfasserin aut Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier ©2017 Walter de Gruyter GmbH, Berlin/Boston Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. Chen, Yuchan aut Huang, Hongbo aut Yang, Hongyan aut Zhang, Weimin aut Sun, Yulin aut Wen, Jing aut Enthalten in Zeitschrift für Naturforschung. C, Biosciences De Gruyter, 1973 72(2016), 3-4 vom: 04. Okt., Seite 129-132 (DE-627)129307394 (DE-600)124636-7 (DE-576)014504936 0939-5075 nnns volume:72 year:2016 number:3-4 day:04 month:10 pages:129-132 https://doi.org/10.1515/znc-2016-0122 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR GBV_ILN_70 GBV_ILN_120 GBV_ILN_121 GBV_ILN_252 GBV_ILN_2015 GBV_ILN_2237 GBV_ILN_4012 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4320 AR 72 2016 3-4 04 10 129-132 |
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10.1515/znc-2016-0122 doi (DE-627)OLC214037231X (DE-B1597)znc-2016-0122-p DE-627 ger DE-627 rakwb eng 500 VZ 570 VZ 12 ssgn BIODIV DE-30 fid Chen, Ziming verfasserin aut Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 2016 Text txt rdacontent ohne Hilfsmittel zu benutzen n rdamedia Band nc rdacarrier ©2017 Walter de Gruyter GmbH, Berlin/Boston Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. Chen, Yuchan aut Huang, Hongbo aut Yang, Hongyan aut Zhang, Weimin aut Sun, Yulin aut Wen, Jing aut Enthalten in Zeitschrift für Naturforschung. C, Biosciences De Gruyter, 1973 72(2016), 3-4 vom: 04. Okt., Seite 129-132 (DE-627)129307394 (DE-600)124636-7 (DE-576)014504936 0939-5075 nnns volume:72 year:2016 number:3-4 day:04 month:10 pages:129-132 https://doi.org/10.1515/znc-2016-0122 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_OLC FID-BIODIV SSG-OLC-PHY SSG-OLC-CHE SSG-OLC-FOR GBV_ILN_70 GBV_ILN_120 GBV_ILN_121 GBV_ILN_252 GBV_ILN_2015 GBV_ILN_2237 GBV_ILN_4012 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4219 GBV_ILN_4277 GBV_ILN_4302 GBV_ILN_4320 AR 72 2016 3-4 04 10 129-132 |
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Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 |
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Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 |
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Chen, Ziming Chen, Yuchan Huang, Hongbo Yang, Hongyan Zhang, Weimin Sun, Yulin Wen, Jing |
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cytochalasin $ p_{1} $, a new cytochalasin from the marine-derived fungus xylaria sp. sof11 |
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Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 |
abstract |
Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. ©2017 Walter de Gruyter GmbH, Berlin/Boston |
abstractGer |
Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. ©2017 Walter de Gruyter GmbH, Berlin/Boston |
abstract_unstemmed |
Abstract A new cytochalasin, named cytochalasin $ P_{1} $ (1), together with four known analogs (2–5) was isolated from marine-derived fungus Xylaria sp. SOF11 from the South China Sea. The structure of the new compound was elucidated on the basis of MS and NMR (1H, 13C, HSQC, HMBC, and NOESY) data analyses. Compounds 1–5 were tested for their cytotoxicities against four tumor cell lines (SF-268, MCF-7, NCI-H460, and HepG-2). Compounds 1–5 showed significant cytotoxicity against two tumor cell lines MCF-7 and SF-268, with the $ IC_{50} $ values varying between 0.33 and 4.17 μM. ©2017 Walter de Gruyter GmbH, Berlin/Boston |
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Cytochalasin $ P_{1} $, a new cytochalasin from the marine-derived fungus Xylaria sp. SOF11 |
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