Novel quinolone-3-carboxylic acid derivatives as anti-HIV-1 agents: design, synthesis, and biological activities

Abstract A new series of quinolone-3-carboxylic acids featuring different hydrophobic groups at N-1, C-2, C-7, and C-8 positions were synthesized and evaluated for their activity against single-cycle replicable HIV NL4-3 as inhibition rate of $ p_{24} $ expression in Hela cells cultures. Most of the...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Hajimahdi, Z. [verfasserIn]

Zabihollahi, R.

Aghasadeghi, M. R.

Ashtiani, S. Hosseini

Zarghi, A.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2016

Schlagwörter:

Anti-HIV activity

Quinolone-3-carboxylic acid

Design, Synthesis

Anmerkung:

© Springer Science+Business Media New York 2016

Übergeordnetes Werk:

Enthalten in: Medicinal chemistry research - Cambridge, Mass. [u.a.] : Birkhäuser Boston, 1991, 25(2016), 9 vom: 13. Juli, Seite 1861-1876

Übergeordnetes Werk:

volume:25 ; year:2016 ; number:9 ; day:13 ; month:07 ; pages:1861-1876

Links:

Volltext

DOI / URN:

10.1007/s00044-016-1631-x

Katalog-ID:

SPR000411418

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