Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial

Purpose Anti-virulence strategies have not been evaluated for the prevention of bacterial infections. Prolonged colonization of intubated patients with Pseudomonas aeruginosa isolates producing high-levels of the quorum sensing (QS)-regulated virulence factor rhamnolipids has been associated with ve...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

van Delden, Christian [verfasserIn]

Köhler, Thilo

Brunner-Ferber, Françoise

François, Bruno

Carlet, Jean

Pechère, Jean-Claude

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2012

Schlagwörter:

Ventilator-associated pneumonia

Virulence

Quorum sensing

Rhamnolipids

Anmerkung:

© © jointly held by Springer and ESICM 2012

Übergeordnetes Werk:

Enthalten in: Intensive care medicine - Berlin : Springer, 1975, 38(2012), 7 vom: 20. Apr., Seite 1118-1125

Übergeordnetes Werk:

volume:38 ; year:2012 ; number:7 ; day:20 ; month:04 ; pages:1118-1125

Links:

Volltext

DOI / URN:

10.1007/s00134-012-2559-3

Katalog-ID:

SPR001217151

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