A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction
Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two g...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zhao, Fengyuan [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Anmerkung: |
© European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 |
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| Übergeordnetes Werk: |
Enthalten in: Knee surgery, sports traumatology, arthroscopy - Berlin : Springer, 1993, 27(2019), 11 vom: 14. März, Seite 3543-3551 |
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| Übergeordnetes Werk: |
volume:27 ; year:2019 ; number:11 ; day:14 ; month:03 ; pages:3543-3551 |
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| DOI / URN: |
10.1007/s00167-019-05420-7 |
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| Katalog-ID: |
SPR001416146 |
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| 100 | 1 | |a Zhao, Fengyuan |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
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| 520 | |a Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. | ||
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| 650 | 4 | |a Tendon-bone healing |7 (dpeaa)DE-He213 | |
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10.1007/s00167-019-05420-7 doi (DE-627)SPR001416146 (SPR)s00167-019-05420-7-e DE-627 ger DE-627 rakwb eng Zhao, Fengyuan verfasserin aut A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 Hu, Xiaoqing aut Zhang, Jiahao aut Shi, Weili aut Ren, Bo aut Huang, Hongjie aut Ao, Yingfang (orcid)0000-0002-8909-2022 aut Enthalten in Knee surgery, sports traumatology, arthroscopy Berlin : Springer, 1993 27(2019), 11 vom: 14. März, Seite 3543-3551 (DE-627)268761787 (DE-600)1473170-8 1433-7347 nnns volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 https://dx.doi.org/10.1007/s00167-019-05420-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 27 2019 11 14 03 3543-3551 |
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10.1007/s00167-019-05420-7 doi (DE-627)SPR001416146 (SPR)s00167-019-05420-7-e DE-627 ger DE-627 rakwb eng Zhao, Fengyuan verfasserin aut A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 Hu, Xiaoqing aut Zhang, Jiahao aut Shi, Weili aut Ren, Bo aut Huang, Hongjie aut Ao, Yingfang (orcid)0000-0002-8909-2022 aut Enthalten in Knee surgery, sports traumatology, arthroscopy Berlin : Springer, 1993 27(2019), 11 vom: 14. März, Seite 3543-3551 (DE-627)268761787 (DE-600)1473170-8 1433-7347 nnns volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 https://dx.doi.org/10.1007/s00167-019-05420-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 27 2019 11 14 03 3543-3551 |
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10.1007/s00167-019-05420-7 doi (DE-627)SPR001416146 (SPR)s00167-019-05420-7-e DE-627 ger DE-627 rakwb eng Zhao, Fengyuan verfasserin aut A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 Hu, Xiaoqing aut Zhang, Jiahao aut Shi, Weili aut Ren, Bo aut Huang, Hongjie aut Ao, Yingfang (orcid)0000-0002-8909-2022 aut Enthalten in Knee surgery, sports traumatology, arthroscopy Berlin : Springer, 1993 27(2019), 11 vom: 14. März, Seite 3543-3551 (DE-627)268761787 (DE-600)1473170-8 1433-7347 nnns volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 https://dx.doi.org/10.1007/s00167-019-05420-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 27 2019 11 14 03 3543-3551 |
| allfieldsGer |
10.1007/s00167-019-05420-7 doi (DE-627)SPR001416146 (SPR)s00167-019-05420-7-e DE-627 ger DE-627 rakwb eng Zhao, Fengyuan verfasserin aut A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 Hu, Xiaoqing aut Zhang, Jiahao aut Shi, Weili aut Ren, Bo aut Huang, Hongjie aut Ao, Yingfang (orcid)0000-0002-8909-2022 aut Enthalten in Knee surgery, sports traumatology, arthroscopy Berlin : Springer, 1993 27(2019), 11 vom: 14. März, Seite 3543-3551 (DE-627)268761787 (DE-600)1473170-8 1433-7347 nnns volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 https://dx.doi.org/10.1007/s00167-019-05420-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 27 2019 11 14 03 3543-3551 |
| allfieldsSound |
10.1007/s00167-019-05420-7 doi (DE-627)SPR001416146 (SPR)s00167-019-05420-7-e DE-627 ger DE-627 rakwb eng Zhao, Fengyuan verfasserin aut A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 Hu, Xiaoqing aut Zhang, Jiahao aut Shi, Weili aut Ren, Bo aut Huang, Hongjie aut Ao, Yingfang (orcid)0000-0002-8909-2022 aut Enthalten in Knee surgery, sports traumatology, arthroscopy Berlin : Springer, 1993 27(2019), 11 vom: 14. März, Seite 3543-3551 (DE-627)268761787 (DE-600)1473170-8 1433-7347 nnns volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 https://dx.doi.org/10.1007/s00167-019-05420-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 27 2019 11 14 03 3543-3551 |
| language |
English |
| source |
Enthalten in Knee surgery, sports traumatology, arthroscopy 27(2019), 11 vom: 14. März, Seite 3543-3551 volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 |
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Enthalten in Knee surgery, sports traumatology, arthroscopy 27(2019), 11 vom: 14. März, Seite 3543-3551 volume:27 year:2019 number:11 day:14 month:03 pages:3543-3551 |
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findex.gbv.de |
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Anterior cruciate ligament Flattened Tendon-bone healing Ribbon-like |
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Knee surgery, sports traumatology, arthroscopy |
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Zhao, Fengyuan @@aut@@ Hu, Xiaoqing @@aut@@ Zhang, Jiahao @@aut@@ Shi, Weili @@aut@@ Ren, Bo @@aut@@ Huang, Hongjie @@aut@@ Ao, Yingfang @@aut@@ |
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2019-03-14T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR001416146</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520002411.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2019 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00167-019-05420-7</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR001416146</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00167-019-05420-7-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zhao, Fengyuan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="2"><subfield code="a">A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. 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|
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Zhao, Fengyuan |
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Zhao, Fengyuan misc Anterior cruciate ligament misc Flattened misc Tendon-bone healing misc Ribbon-like A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
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A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction Anterior cruciate ligament (dpeaa)DE-He213 Flattened (dpeaa)DE-He213 Tendon-bone healing (dpeaa)DE-He213 Ribbon-like (dpeaa)DE-He213 |
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misc Anterior cruciate ligament misc Flattened misc Tendon-bone healing misc Ribbon-like |
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misc Anterior cruciate ligament misc Flattened misc Tendon-bone healing misc Ribbon-like |
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A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
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A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
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Zhao, Fengyuan |
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Knee surgery, sports traumatology, arthroscopy |
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Zhao, Fengyuan Hu, Xiaoqing Zhang, Jiahao Shi, Weili Ren, Bo Huang, Hongjie Ao, Yingfang |
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more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after acl reconstruction |
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A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
| abstract |
Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 |
| abstractGer |
Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 |
| abstract_unstemmed |
Purpose The purpose of this study was to evaluate whether a flattened bone tunnel has a positive effect on the tendon–bone healing (TBH) process in the early period after anterior cruciate ligament (ACL) reconstruction. Methods Seventy-two New Zealand White rabbits were randomly allocated into two groups, the flattened tunnel (FT) group and the conventional round tunnel (RT) group. We compared the cross-sectional areas and diameters of the bone tunnels between the two groups through computed tomography (CT) scanning. TBH results between the two groups were assessed by histological analysis, micro-CT scanning and biomechanical tests at 4 weeks, 8 weeks and 12 weeks after operation. Results The cross-sectional areas of the bone tunnels between the two groups were almost the same. However, the shape of bone tunnels in the FT group was more flattened. A faster cellular and collagen remoulding process were found in the FT group. Semiquantitative histological analysis of Safranin O staining showed that there was more fibrocartilage formation in the interface region in the FT group (P < 0.05). Sirius Red staining showed that the tissues in the interface areas were more intense in the FT group. Micro-CT scanning showed that more new bone formation could be found in the interface region in the FT group. The biomechanical tests also showed that FT ACL reconstruction will result in a stronger regenerated tendon–bone interface. Conclusions Our study found that a flattened bone tunnel accelerated TBH in the early period after ACL reconstruction surgery in a rabbit model, which lays the groundwork for further clinical practice of this ACL reconstruction method. © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 |
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A more flattened bone tunnel has a positive effect on tendon–bone healing in the early period after ACL reconstruction |
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https://dx.doi.org/10.1007/s00167-019-05420-7 |
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Hu, Xiaoqing Zhang, Jiahao Shi, Weili Ren, Bo Huang, Hongjie Ao, Yingfang |
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| score |
7.4006166 |