Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus
Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the litera...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Khan, A. A. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Anmerkung: |
© The Author(s) 2016 |
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| Übergeordnetes Werk: |
Enthalten in: Osteoporosis international - London : Springer, 1990, 28(2016), 1 vom: 09. Sept., Seite 1-19 |
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| Übergeordnetes Werk: |
volume:28 ; year:2016 ; number:1 ; day:09 ; month:09 ; pages:1-19 |
| Links: |
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| DOI / URN: |
10.1007/s00198-016-3716-2 |
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| Katalog-ID: |
SPR001728407 |
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| 100 | 1 | |a Khan, A. A. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
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| 520 | |a Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. | ||
| 650 | 4 | |a Diagnosis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Management |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Osteoporosis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Primary hyperparathyroidism |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Surgery |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Treatment |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Hanley, D. A. |4 aut | |
| 700 | 1 | |a Rizzoli, R. |4 aut | |
| 700 | 1 | |a Bollerslev, J. |4 aut | |
| 700 | 1 | |a Young, J.E.M |4 aut | |
| 700 | 1 | |a Rejnmark, L. |4 aut | |
| 700 | 1 | |a Thakker, R. |4 aut | |
| 700 | 1 | |a D’Amour, P. |4 aut | |
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| 700 | 1 | |a Goltzman, D. |4 aut | |
| 700 | 1 | |a Kaiser, S. |4 aut | |
| 700 | 1 | |a Cusano, N. E. |4 aut | |
| 700 | 1 | |a Bouillon, R. |4 aut | |
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| 700 | 1 | |a Kung, A. W. |4 aut | |
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| 700 | 1 | |a Bhadada, S. K. |4 aut | |
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| 700 | 1 | |a Eastell, R. |4 aut | |
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| 700 | 1 | |a Udelsman, R. |4 aut | |
| 700 | 1 | |a Davison, K. Shawn |4 aut | |
| 700 | 1 | |a Potts, J. T. |4 aut | |
| 700 | 1 | |a Brandi, M. L. |4 aut | |
| 700 | 1 | |a Bilezikian, J. P. |4 aut | |
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10.1007/s00198-016-3716-2 doi (DE-627)SPR001728407 (SPR)s00198-016-3716-2-e DE-627 ger DE-627 rakwb eng Khan, A. A. verfasserin aut Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 Hanley, D. A. aut Rizzoli, R. aut Bollerslev, J. aut Young, J.E.M aut Rejnmark, L. aut Thakker, R. aut D’Amour, P. aut Paul, T. aut Van Uum, S. aut Shrayyef, M. Zakaria aut Goltzman, D. aut Kaiser, S. aut Cusano, N. E. aut Bouillon, R. aut Mosekilde, L. aut Kung, A. W. aut Rao, S. D. aut Bhadada, S. K. aut Clarke, B. L. aut Liu, J. aut Duh, Q. aut Lewiecki, E. Michael aut Bandeira, F. aut Eastell, R. aut Marcocci, C. aut Silverberg, S. J. aut Udelsman, R. aut Davison, K. Shawn aut Potts, J. T. aut Brandi, M. L. aut Bilezikian, J. P. aut Enthalten in Osteoporosis international London : Springer, 1990 28(2016), 1 vom: 09. Sept., Seite 1-19 (DE-627)271596597 (DE-600)1480645-9 1433-2965 nnns volume:28 year:2016 number:1 day:09 month:09 pages:1-19 https://dx.doi.org/10.1007/s00198-016-3716-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 28 2016 1 09 09 1-19 |
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10.1007/s00198-016-3716-2 doi (DE-627)SPR001728407 (SPR)s00198-016-3716-2-e DE-627 ger DE-627 rakwb eng Khan, A. A. verfasserin aut Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 Hanley, D. A. aut Rizzoli, R. aut Bollerslev, J. aut Young, J.E.M aut Rejnmark, L. aut Thakker, R. aut D’Amour, P. aut Paul, T. aut Van Uum, S. aut Shrayyef, M. Zakaria aut Goltzman, D. aut Kaiser, S. aut Cusano, N. E. aut Bouillon, R. aut Mosekilde, L. aut Kung, A. W. aut Rao, S. D. aut Bhadada, S. K. aut Clarke, B. L. aut Liu, J. aut Duh, Q. aut Lewiecki, E. Michael aut Bandeira, F. aut Eastell, R. aut Marcocci, C. aut Silverberg, S. J. aut Udelsman, R. aut Davison, K. Shawn aut Potts, J. T. aut Brandi, M. L. aut Bilezikian, J. P. aut Enthalten in Osteoporosis international London : Springer, 1990 28(2016), 1 vom: 09. Sept., Seite 1-19 (DE-627)271596597 (DE-600)1480645-9 1433-2965 nnns volume:28 year:2016 number:1 day:09 month:09 pages:1-19 https://dx.doi.org/10.1007/s00198-016-3716-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 28 2016 1 09 09 1-19 |
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10.1007/s00198-016-3716-2 doi (DE-627)SPR001728407 (SPR)s00198-016-3716-2-e DE-627 ger DE-627 rakwb eng Khan, A. A. verfasserin aut Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 Hanley, D. A. aut Rizzoli, R. aut Bollerslev, J. aut Young, J.E.M aut Rejnmark, L. aut Thakker, R. aut D’Amour, P. aut Paul, T. aut Van Uum, S. aut Shrayyef, M. Zakaria aut Goltzman, D. aut Kaiser, S. aut Cusano, N. E. aut Bouillon, R. aut Mosekilde, L. aut Kung, A. W. aut Rao, S. D. aut Bhadada, S. K. aut Clarke, B. L. aut Liu, J. aut Duh, Q. aut Lewiecki, E. Michael aut Bandeira, F. aut Eastell, R. aut Marcocci, C. aut Silverberg, S. J. aut Udelsman, R. aut Davison, K. Shawn aut Potts, J. T. aut Brandi, M. L. aut Bilezikian, J. P. aut Enthalten in Osteoporosis international London : Springer, 1990 28(2016), 1 vom: 09. Sept., Seite 1-19 (DE-627)271596597 (DE-600)1480645-9 1433-2965 nnns volume:28 year:2016 number:1 day:09 month:09 pages:1-19 https://dx.doi.org/10.1007/s00198-016-3716-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 28 2016 1 09 09 1-19 |
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10.1007/s00198-016-3716-2 doi (DE-627)SPR001728407 (SPR)s00198-016-3716-2-e DE-627 ger DE-627 rakwb eng Khan, A. A. verfasserin aut Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 Hanley, D. A. aut Rizzoli, R. aut Bollerslev, J. aut Young, J.E.M aut Rejnmark, L. aut Thakker, R. aut D’Amour, P. aut Paul, T. aut Van Uum, S. aut Shrayyef, M. Zakaria aut Goltzman, D. aut Kaiser, S. aut Cusano, N. E. aut Bouillon, R. aut Mosekilde, L. aut Kung, A. W. aut Rao, S. D. aut Bhadada, S. K. aut Clarke, B. L. aut Liu, J. aut Duh, Q. aut Lewiecki, E. Michael aut Bandeira, F. aut Eastell, R. aut Marcocci, C. aut Silverberg, S. J. aut Udelsman, R. aut Davison, K. Shawn aut Potts, J. T. aut Brandi, M. L. aut Bilezikian, J. P. aut Enthalten in Osteoporosis international London : Springer, 1990 28(2016), 1 vom: 09. Sept., Seite 1-19 (DE-627)271596597 (DE-600)1480645-9 1433-2965 nnns volume:28 year:2016 number:1 day:09 month:09 pages:1-19 https://dx.doi.org/10.1007/s00198-016-3716-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 28 2016 1 09 09 1-19 |
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10.1007/s00198-016-3716-2 doi (DE-627)SPR001728407 (SPR)s00198-016-3716-2-e DE-627 ger DE-627 rakwb eng Khan, A. A. verfasserin aut Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © The Author(s) 2016 Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 Hanley, D. A. aut Rizzoli, R. aut Bollerslev, J. aut Young, J.E.M aut Rejnmark, L. aut Thakker, R. aut D’Amour, P. aut Paul, T. aut Van Uum, S. aut Shrayyef, M. Zakaria aut Goltzman, D. aut Kaiser, S. aut Cusano, N. E. aut Bouillon, R. aut Mosekilde, L. aut Kung, A. W. aut Rao, S. D. aut Bhadada, S. K. aut Clarke, B. L. aut Liu, J. aut Duh, Q. aut Lewiecki, E. Michael aut Bandeira, F. aut Eastell, R. aut Marcocci, C. aut Silverberg, S. J. aut Udelsman, R. aut Davison, K. Shawn aut Potts, J. T. aut Brandi, M. L. aut Bilezikian, J. P. aut Enthalten in Osteoporosis international London : Springer, 1990 28(2016), 1 vom: 09. Sept., Seite 1-19 (DE-627)271596597 (DE-600)1480645-9 1433-2965 nnns volume:28 year:2016 number:1 day:09 month:09 pages:1-19 https://dx.doi.org/10.1007/s00198-016-3716-2 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 28 2016 1 09 09 1-19 |
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Khan, A. A. @@aut@@ Hanley, D. A. @@aut@@ Rizzoli, R. @@aut@@ Bollerslev, J. @@aut@@ Young, J.E.M @@aut@@ Rejnmark, L. @@aut@@ Thakker, R. @@aut@@ D’Amour, P. @@aut@@ Paul, T. @@aut@@ Van Uum, S. @@aut@@ Shrayyef, M. Zakaria @@aut@@ Goltzman, D. @@aut@@ Kaiser, S. @@aut@@ Cusano, N. E. @@aut@@ Bouillon, R. @@aut@@ Mosekilde, L. @@aut@@ Kung, A. W. @@aut@@ Rao, S. D. @@aut@@ Bhadada, S. K. @@aut@@ Clarke, B. L. @@aut@@ Liu, J. @@aut@@ Duh, Q. @@aut@@ Lewiecki, E. Michael @@aut@@ Bandeira, F. @@aut@@ Eastell, R. @@aut@@ Marcocci, C. @@aut@@ Silverberg, S. J. @@aut@@ Udelsman, R. @@aut@@ Davison, K. Shawn @@aut@@ Potts, J. T. @@aut@@ Brandi, M. L. @@aut@@ Bilezikian, J. P. @@aut@@ |
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| author |
Khan, A. A. |
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Khan, A. A. misc Diagnosis misc Management misc Osteoporosis misc Primary hyperparathyroidism misc Surgery misc Treatment Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
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Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus Diagnosis (dpeaa)DE-He213 Management (dpeaa)DE-He213 Osteoporosis (dpeaa)DE-He213 Primary hyperparathyroidism (dpeaa)DE-He213 Surgery (dpeaa)DE-He213 Treatment (dpeaa)DE-He213 |
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Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
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Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
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Khan, A. A. |
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Khan, A. A. Hanley, D. A. Rizzoli, R. Bollerslev, J. Young, J.E.M Rejnmark, L. Thakker, R. D’Amour, P. Paul, T. Van Uum, S. Shrayyef, M. Zakaria Goltzman, D. Kaiser, S. Cusano, N. E. Bouillon, R. Mosekilde, L. Kung, A. W. Rao, S. D. Bhadada, S. K. Clarke, B. L. Liu, J. Duh, Q. Lewiecki, E. Michael Bandeira, F. Eastell, R. Marcocci, C. Silverberg, S. J. Udelsman, R. Davison, K. Shawn Potts, J. T. Brandi, M. L. Bilezikian, J. P. |
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Khan, A. A. |
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10.1007/s00198-016-3716-2 |
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primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. a canadian and international consensus |
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Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
| abstract |
Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. © The Author(s) 2016 |
| abstractGer |
Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. © The Author(s) 2016 |
| abstract_unstemmed |
Abstract The purpose of this review is to assess the most recent evidence in the management of primary hyperparathyroidism (PHPT) and provide updated recommendations for its evaluation, diagnosis and treatment. A Medline search of "Hyperparathyroidism. Primary" was conducted and the literature with the highest levels of evidence were reviewed and used to formulate recommendations. PHPT is a common endocrine disorder usually discovered by routine biochemical screening. PHPT is defined as hypercalcemia with increased or inappropriately normal plasma parathyroid hormone (PTH). It is most commonly seen after the age of 50 years, with women predominating by three to fourfold. In countries with routine multichannel screening, PHPT is identified earlier and may be asymptomatic. Where biochemical testing is not routine, PHPT is more likely to present with skeletal complications, or nephrolithiasis. Parathyroidectomy (PTx) is indicated for those with symptomatic disease. For asymptomatic patients, recent guidelines have recommended criteria for surgery, however PTx can also be considered in those who do not meet criteria, and prefer surgery. Non-surgical therapies are available when surgery is not appropriate. This review presents the current state of the art in the diagnosis and management of PHPT and updates the Canadian Position paper on PHPT. An overview of the impact of PHPT on the skeleton and other target organs is presented with international consensus. Differences in the international presentation of this condition are also summarized. © The Author(s) 2016 |
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Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus |
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Hanley, D. A. Rizzoli, R. Bollerslev, J. Young, J.E.M Rejnmark, L. Thakker, R. D’Amour, P. Paul, T. Van Uum, S. Shrayyef, M. Zakaria Goltzman, D. Kaiser, S. Cusano, N. E. Bouillon, R. Mosekilde, L. Kung, A. W. Rao, S. D. Bhadada, S. K. Clarke, B. L. Liu, J. Duh, Q. Lewiecki, E. Michael Bandeira, F. Eastell, R. Marcocci, C. Silverberg, S. J. Udelsman, R. Davison, K. Shawn Potts, J. T. Brandi, M. L. Bilezikian, J. P. |
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Hanley, D. A. Rizzoli, R. Bollerslev, J. Young, J.E.M Rejnmark, L. Thakker, R. D’Amour, P. Paul, T. Van Uum, S. Shrayyef, M. Zakaria Goltzman, D. Kaiser, S. Cusano, N. E. Bouillon, R. Mosekilde, L. Kung, A. W. Rao, S. D. Bhadada, S. K. Clarke, B. L. Liu, J. Duh, Q. Lewiecki, E. Michael Bandeira, F. Eastell, R. Marcocci, C. Silverberg, S. J. Udelsman, R. Davison, K. Shawn Potts, J. T. Brandi, M. L. Bilezikian, J. P. |
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10.1007/s00198-016-3716-2 |
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2024-07-04T00:08:01.224Z |
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| score |
7.401886 |