Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function

Rationale The transition from initial drug use to drug addiction has been proposed to result from an allostatic decrease in reward function driven by an overactivation of brain antireward processes. Objectives How decreased reward function explains compulsive drug use is not entirely clear at presen...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Ahmed, Serge H. [verfasserIn]

Koob, George F.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2005

Schlagwörter:

Reward

Reinforcement

Self-administration

Self-medication

Self-regulation

Dopamine

Cocaine

Laboratory environment

Anmerkung:

© Springer-Verlag 2005

Übergeordnetes Werk:

Enthalten in: Psychopharmacology - Berlin : Springer, 1959, 180(2005), 3 vom: 25. Feb., Seite 473-490

Übergeordnetes Werk:

volume:180 ; year:2005 ; number:3 ; day:25 ; month:02 ; pages:473-490

Links:

Volltext

DOI / URN:

10.1007/s00213-005-2180-z

Katalog-ID:

SPR001995243

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