A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens
Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cel...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ding, Zhongyang [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2012 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag 2012 |
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| Übergeordnetes Werk: |
Enthalten in: European food research and technology - Berlin : Springer, 1999, 234(2012), 6 vom: 01. Apr., Seite 1043-1048 |
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| Übergeordnetes Werk: |
volume:234 ; year:2012 ; number:6 ; day:01 ; month:04 ; pages:1043-1048 |
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| DOI / URN: |
10.1007/s00217-012-1723-x |
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| Katalog-ID: |
SPR002304880 |
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| 245 | 1 | 2 | |a A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens |
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| 520 | |a Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. | ||
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| 650 | 4 | |a Oxygen supply control |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Ai, Lianzhong |4 aut | |
| 700 | 1 | |a Ouyang, Anran |4 aut | |
| 700 | 1 | |a Ding, Mingliang |4 aut | |
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| 700 | 1 | |a Wang, Boda |4 aut | |
| 700 | 1 | |a Liu, Shuangping |4 aut | |
| 700 | 1 | |a Gu, Zhenghua |4 aut | |
| 700 | 1 | |a Zhang, Liang |4 aut | |
| 700 | 1 | |a Shi, Guiyang |4 aut | |
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10.1007/s00217-012-1723-x doi (DE-627)SPR002304880 (SPR)s00217-012-1723-x-e DE-627 ger DE-627 rakwb eng Ding, Zhongyang verfasserin aut A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag 2012 Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 Ai, Lianzhong aut Ouyang, Anran aut Ding, Mingliang aut Wang, Wangfei aut Wang, Boda aut Liu, Shuangping aut Gu, Zhenghua aut Zhang, Liang aut Shi, Guiyang aut Enthalten in European food research and technology Berlin : Springer, 1999 234(2012), 6 vom: 01. Apr., Seite 1043-1048 (DE-627)27012859X (DE-600)1476605-X 1438-2385 nnns volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 https://dx.doi.org/10.1007/s00217-012-1723-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 234 2012 6 01 04 1043-1048 |
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10.1007/s00217-012-1723-x doi (DE-627)SPR002304880 (SPR)s00217-012-1723-x-e DE-627 ger DE-627 rakwb eng Ding, Zhongyang verfasserin aut A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag 2012 Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 Ai, Lianzhong aut Ouyang, Anran aut Ding, Mingliang aut Wang, Wangfei aut Wang, Boda aut Liu, Shuangping aut Gu, Zhenghua aut Zhang, Liang aut Shi, Guiyang aut Enthalten in European food research and technology Berlin : Springer, 1999 234(2012), 6 vom: 01. Apr., Seite 1043-1048 (DE-627)27012859X (DE-600)1476605-X 1438-2385 nnns volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 https://dx.doi.org/10.1007/s00217-012-1723-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 234 2012 6 01 04 1043-1048 |
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10.1007/s00217-012-1723-x doi (DE-627)SPR002304880 (SPR)s00217-012-1723-x-e DE-627 ger DE-627 rakwb eng Ding, Zhongyang verfasserin aut A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag 2012 Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 Ai, Lianzhong aut Ouyang, Anran aut Ding, Mingliang aut Wang, Wangfei aut Wang, Boda aut Liu, Shuangping aut Gu, Zhenghua aut Zhang, Liang aut Shi, Guiyang aut Enthalten in European food research and technology Berlin : Springer, 1999 234(2012), 6 vom: 01. Apr., Seite 1043-1048 (DE-627)27012859X (DE-600)1476605-X 1438-2385 nnns volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 https://dx.doi.org/10.1007/s00217-012-1723-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 234 2012 6 01 04 1043-1048 |
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10.1007/s00217-012-1723-x doi (DE-627)SPR002304880 (SPR)s00217-012-1723-x-e DE-627 ger DE-627 rakwb eng Ding, Zhongyang verfasserin aut A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag 2012 Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 Ai, Lianzhong aut Ouyang, Anran aut Ding, Mingliang aut Wang, Wangfei aut Wang, Boda aut Liu, Shuangping aut Gu, Zhenghua aut Zhang, Liang aut Shi, Guiyang aut Enthalten in European food research and technology Berlin : Springer, 1999 234(2012), 6 vom: 01. Apr., Seite 1043-1048 (DE-627)27012859X (DE-600)1476605-X 1438-2385 nnns volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 https://dx.doi.org/10.1007/s00217-012-1723-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 234 2012 6 01 04 1043-1048 |
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10.1007/s00217-012-1723-x doi (DE-627)SPR002304880 (SPR)s00217-012-1723-x-e DE-627 ger DE-627 rakwb eng Ding, Zhongyang verfasserin aut A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag 2012 Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 Ai, Lianzhong aut Ouyang, Anran aut Ding, Mingliang aut Wang, Wangfei aut Wang, Boda aut Liu, Shuangping aut Gu, Zhenghua aut Zhang, Liang aut Shi, Guiyang aut Enthalten in European food research and technology Berlin : Springer, 1999 234(2012), 6 vom: 01. Apr., Seite 1043-1048 (DE-627)27012859X (DE-600)1476605-X 1438-2385 nnns volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 https://dx.doi.org/10.1007/s00217-012-1723-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 234 2012 6 01 04 1043-1048 |
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Enthalten in European food research and technology 234(2012), 6 vom: 01. Apr., Seite 1043-1048 volume:234 year:2012 number:6 day:01 month:04 pages:1043-1048 |
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Ding, Zhongyang @@aut@@ Ai, Lianzhong @@aut@@ Ouyang, Anran @@aut@@ Ding, Mingliang @@aut@@ Wang, Wangfei @@aut@@ Wang, Boda @@aut@@ Liu, Shuangping @@aut@@ Gu, Zhenghua @@aut@@ Zhang, Liang @@aut@@ Shi, Guiyang @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR002304880</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230327152652.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2012 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00217-012-1723-x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR002304880</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00217-012-1723-x-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ding, Zhongyang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="2"><subfield code="a">A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag 2012</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. 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A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens K (dpeaa)DE-He213 a (dpeaa)DE-He213 Milk-clotting enzyme (dpeaa)DE-He213 Oxygen supply control (dpeaa)DE-He213 |
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A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens |
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Ding, Zhongyang Ai, Lianzhong Ouyang, Anran Ding, Mingliang Wang, Wangfei Wang, Boda Liu, Shuangping Gu, Zhenghua Zhang, Liang Shi, Guiyang |
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two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by bacillus amyloliquefaciens |
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A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens |
| abstract |
Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. © Springer-Verlag 2012 |
| abstractGer |
Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. © Springer-Verlag 2012 |
| abstract_unstemmed |
Abstract To enhance the yield and productivity of milk-clotting enzyme (MCE) by Bacillus amyloliquefaciens, a two-stage oxygen supply control strategy was proposed and successfully applied in the MCE fermentation. During the first 16 h, $ K_{L} $a was controlled at 72.2 $ h^{−1} $ to obtain high cell growth rate (v) and MCE activity (MCA) productivity (rMCA). Subsequently, $ K_{L} $a was controlled at 33.9 $ h^{−1} $ to maintain high specific MCA productivity (qMCA). Using this strategy, MCA peaked at 36 h with the MCA of 6,590.41 SU $ ml^{−1} $, which was 18 h earlier than other investigated processes. The concept and results described represent the basis of an industrial scale-up process to achieve high MCE yield, MCA productivity and MCA/proteolytic activity. © Springer-Verlag 2012 |
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A two-stage oxygen supply control strategy for enhancing milk-clotting enzyme production by Bacillus amyloliquefaciens |
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Ai, Lianzhong Ouyang, Anran Ding, Mingliang Wang, Wangfei Wang, Boda Liu, Shuangping Gu, Zhenghua Zhang, Liang Shi, Guiyang |
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Ai, Lianzhong Ouyang, Anran Ding, Mingliang Wang, Wangfei Wang, Boda Liu, Shuangping Gu, Zhenghua Zhang, Liang Shi, Guiyang |
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| score |
7.4001894 |