Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results
Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients con...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Tinti, Erica [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag Berlin Heidelberg 2013 |
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| Übergeordnetes Werk: |
Enthalten in: European journal of nuclear medicine and molecular imaging - Heidelberg [u.a.] : Springer-Verl., 2002, 41(2013), 1 vom: 20. Sept., Seite 167-173 |
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| Übergeordnetes Werk: |
volume:41 ; year:2013 ; number:1 ; day:20 ; month:09 ; pages:167-173 |
| Links: |
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| DOI / URN: |
10.1007/s00259-013-2549-x |
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| Katalog-ID: |
SPR003149323 |
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| 100 | 1 | |a Tinti, Erica |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
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| 520 | |a Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. | ||
| 650 | 4 | |a [ |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a I]-MIBG |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cardiac innervation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a CZT |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Ultrafast cardiac camera |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Positano, Vincenzo |4 aut | |
| 700 | 1 | |a Giorgetti, Assuero |4 aut | |
| 700 | 1 | |a Marzullo, Paolo |4 aut | |
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10.1007/s00259-013-2549-x doi (DE-627)SPR003149323 (SPR)s00259-013-2549-x-e DE-627 ger DE-627 rakwb eng Tinti, Erica verfasserin aut Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2013 Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. [ (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 Positano, Vincenzo aut Giorgetti, Assuero aut Marzullo, Paolo aut Enthalten in European journal of nuclear medicine and molecular imaging Heidelberg [u.a.] : Springer-Verl., 2002 41(2013), 1 vom: 20. Sept., Seite 167-173 (DE-627)359787258 (DE-600)2098375-X 1619-7089 nnns volume:41 year:2013 number:1 day:20 month:09 pages:167-173 https://dx.doi.org/10.1007/s00259-013-2549-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2013 1 20 09 167-173 |
| spelling |
10.1007/s00259-013-2549-x doi (DE-627)SPR003149323 (SPR)s00259-013-2549-x-e DE-627 ger DE-627 rakwb eng Tinti, Erica verfasserin aut Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2013 Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. [ (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 Positano, Vincenzo aut Giorgetti, Assuero aut Marzullo, Paolo aut Enthalten in European journal of nuclear medicine and molecular imaging Heidelberg [u.a.] : Springer-Verl., 2002 41(2013), 1 vom: 20. Sept., Seite 167-173 (DE-627)359787258 (DE-600)2098375-X 1619-7089 nnns volume:41 year:2013 number:1 day:20 month:09 pages:167-173 https://dx.doi.org/10.1007/s00259-013-2549-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2013 1 20 09 167-173 |
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10.1007/s00259-013-2549-x doi (DE-627)SPR003149323 (SPR)s00259-013-2549-x-e DE-627 ger DE-627 rakwb eng Tinti, Erica verfasserin aut Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2013 Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. [ (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 Positano, Vincenzo aut Giorgetti, Assuero aut Marzullo, Paolo aut Enthalten in European journal of nuclear medicine and molecular imaging Heidelberg [u.a.] : Springer-Verl., 2002 41(2013), 1 vom: 20. Sept., Seite 167-173 (DE-627)359787258 (DE-600)2098375-X 1619-7089 nnns volume:41 year:2013 number:1 day:20 month:09 pages:167-173 https://dx.doi.org/10.1007/s00259-013-2549-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2013 1 20 09 167-173 |
| allfieldsGer |
10.1007/s00259-013-2549-x doi (DE-627)SPR003149323 (SPR)s00259-013-2549-x-e DE-627 ger DE-627 rakwb eng Tinti, Erica verfasserin aut Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2013 Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. [ (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 Positano, Vincenzo aut Giorgetti, Assuero aut Marzullo, Paolo aut Enthalten in European journal of nuclear medicine and molecular imaging Heidelberg [u.a.] : Springer-Verl., 2002 41(2013), 1 vom: 20. Sept., Seite 167-173 (DE-627)359787258 (DE-600)2098375-X 1619-7089 nnns volume:41 year:2013 number:1 day:20 month:09 pages:167-173 https://dx.doi.org/10.1007/s00259-013-2549-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2013 1 20 09 167-173 |
| allfieldsSound |
10.1007/s00259-013-2549-x doi (DE-627)SPR003149323 (SPR)s00259-013-2549-x-e DE-627 ger DE-627 rakwb eng Tinti, Erica verfasserin aut Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2013 Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. [ (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 Positano, Vincenzo aut Giorgetti, Assuero aut Marzullo, Paolo aut Enthalten in European journal of nuclear medicine and molecular imaging Heidelberg [u.a.] : Springer-Verl., 2002 41(2013), 1 vom: 20. Sept., Seite 167-173 (DE-627)359787258 (DE-600)2098375-X 1619-7089 nnns volume:41 year:2013 number:1 day:20 month:09 pages:167-173 https://dx.doi.org/10.1007/s00259-013-2549-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 41 2013 1 20 09 167-173 |
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English |
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Enthalten in European journal of nuclear medicine and molecular imaging 41(2013), 1 vom: 20. Sept., Seite 167-173 volume:41 year:2013 number:1 day:20 month:09 pages:167-173 |
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Enthalten in European journal of nuclear medicine and molecular imaging 41(2013), 1 vom: 20. Sept., Seite 167-173 volume:41 year:2013 number:1 day:20 month:09 pages:167-173 |
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[ I]-MIBG Cardiac innervation CZT Ultrafast cardiac camera |
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European journal of nuclear medicine and molecular imaging |
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Tinti, Erica @@aut@@ Positano, Vincenzo @@aut@@ Giorgetti, Assuero @@aut@@ Marzullo, Paolo @@aut@@ |
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2013-09-20T00:00:00Z |
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In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">[</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">I]-MIBG</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiac innervation</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">CZT</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ultrafast cardiac camera</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Positano, Vincenzo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Giorgetti, Assuero</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Marzullo, Paolo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">European journal of nuclear medicine and molecular imaging</subfield><subfield code="d">Heidelberg [u.a.] : Springer-Verl., 2002</subfield><subfield code="g">41(2013), 1 vom: 20. 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Tinti, Erica |
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Tinti, Erica misc [ misc I]-MIBG misc Cardiac innervation misc CZT misc Ultrafast cardiac camera Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
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Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results (dpeaa)DE-He213 I]-MIBG (dpeaa)DE-He213 Cardiac innervation (dpeaa)DE-He213 CZT (dpeaa)DE-He213 Ultrafast cardiac camera (dpeaa)DE-He213 |
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Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
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Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
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Tinti, Erica |
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Tinti, Erica Positano, Vincenzo Giorgetti, Assuero Marzullo, Paolo |
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feasibility of [123i]-meta-iodobenzylguanidine dynamic 3-d kinetic analysis in vivo using a czt ultrafast camera: preliminary results |
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Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
| abstract |
Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. © Springer-Verlag Berlin Heidelberg 2013 |
| abstractGer |
Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. © Springer-Verlag Berlin Heidelberg 2013 |
| abstract_unstemmed |
Purpose No data are yet available in the literature concerning 3-D [123I]-meta-iodobenzylguanidine ([123I]-MIBG) kinetics in vivo. In this study we investigated the feasibility of dynamic 3-D [123I]-MIBG kinetic analysis using a CZT ultrafast camera. Methods The study group comprised 16 patients consecutively scheduled for [123I]-MIBG cardiac scintigraphy for clinical purpose who were studied using a CZT camera (NM530c, GE). Dynamic acquisition in list mode was simultaneously started with a bolus injection of the radiotracer (185–370 MBq) for an overall duration of 900 s. A temporal series of 3-D volumes was reconstructed from the first 150 s of dynamic acquisition with a temporal resolution of 5 s. A summed cardiac image was also reconstructed to serve as reference for blood pool (BP) and left ventricle (LV) wall identification. BP and LV volumes of interest (VOIs) were manually drawn to cover the whole heart and automatically reported on the reframed volumes. Time–activity curves (TACs) for the BP and LV were extracted by averaging the signal intensity in the respective VOI in each time frame. BP TACs were fitted to a gamma variate model while LV TACs were fitted to a bicompartmental model. Results TAC analysis was feasible in all patients with good interobserver reproducibility. BP TACs were well described by a gamma variate model as they represent the first pass of the tracer. The first compartment of LV TACs corresponded to contamination spillover of the LV signal from the BP signal. The LV second compartment characterized the uptake of the tracer in the myocardium quantified in terms of maximum signal intensity value (6.95 ± 2.76 counts/$ mm^{3} $/$ s^{2} $), maximum up-slope value (0.36 ± 0.15 counts/$ mm^{3} $/s) and normalized washout of the signal value (7.0 ± 0.6 %). Conclusion Using CZT technology and dynamic 3-D acquisition, analysis of [123I]-MIBG radiotracer kinetics in vivo is feasible and may provide pathophysiological information in addition to that available with standard planar and SPECT imaging. © Springer-Verlag Berlin Heidelberg 2013 |
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Feasibility of [123I]-meta-iodobenzylguanidine dynamic 3-D kinetic analysis in vivo using a CZT ultrafast camera: preliminary results |
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Positano, Vincenzo Giorgetti, Assuero Marzullo, Paolo |
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| score |
7.398122 |