Variability in computed tomography diameter measurements of solid renal masses
Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images perform...
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Gespeichert in:
| Autor*in: |
Orton, Lorenzo P. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer Science+Business Media New York 2014 |
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| Übergeordnetes Werk: |
Enthalten in: Abdominal radiology - [Boston, MA] : Springer US, 2016, 39(2014), 3 vom: 18. Feb., Seite 533-542 |
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| Übergeordnetes Werk: |
volume:39 ; year:2014 ; number:3 ; day:18 ; month:02 ; pages:533-542 |
| Links: |
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| DOI / URN: |
10.1007/s00261-014-0088-y |
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SPR003192539 |
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| 100 | 1 | |a Orton, Lorenzo P. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Variability in computed tomography diameter measurements of solid renal masses |
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| 520 | |a Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. | ||
| 650 | 4 | |a Renal mass measurements |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Computed tomography |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Solid renal mass |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Cohan, Richard H. |4 aut | |
| 700 | 1 | |a Davenport, Matthew S. |4 aut | |
| 700 | 1 | |a Parker, Robert A. |4 aut | |
| 700 | 1 | |a Parameswaran, Aishwarya |4 aut | |
| 700 | 1 | |a Caoili, Elaine M. |4 aut | |
| 700 | 1 | |a Kaza, Ravi K. |4 aut | |
| 700 | 1 | |a Francis, Isaac R. |4 aut | |
| 700 | 1 | |a Ellis, James H. |4 aut | |
| 700 | 1 | |a Wolf, J. Stuart |4 aut | |
| 700 | 1 | |a Hafez, Khaled |4 aut | |
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10.1007/s00261-014-0088-y doi (DE-627)SPR003192539 (SPR)s00261-014-0088-y-e DE-627 ger DE-627 rakwb eng Orton, Lorenzo P. verfasserin aut Variability in computed tomography diameter measurements of solid renal masses 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media New York 2014 Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. Renal mass measurements (dpeaa)DE-He213 Computed tomography (dpeaa)DE-He213 Solid renal mass (dpeaa)DE-He213 Cohan, Richard H. aut Davenport, Matthew S. aut Parker, Robert A. aut Parameswaran, Aishwarya aut Caoili, Elaine M. aut Kaza, Ravi K. aut Francis, Isaac R. aut Ellis, James H. aut Wolf, J. Stuart aut Hafez, Khaled aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 39(2014), 3 vom: 18. Feb., Seite 533-542 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:39 year:2014 number:3 day:18 month:02 pages:533-542 https://dx.doi.org/10.1007/s00261-014-0088-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_150 GBV_ILN_2113 AR 39 2014 3 18 02 533-542 |
| spelling |
10.1007/s00261-014-0088-y doi (DE-627)SPR003192539 (SPR)s00261-014-0088-y-e DE-627 ger DE-627 rakwb eng Orton, Lorenzo P. verfasserin aut Variability in computed tomography diameter measurements of solid renal masses 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media New York 2014 Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. Renal mass measurements (dpeaa)DE-He213 Computed tomography (dpeaa)DE-He213 Solid renal mass (dpeaa)DE-He213 Cohan, Richard H. aut Davenport, Matthew S. aut Parker, Robert A. aut Parameswaran, Aishwarya aut Caoili, Elaine M. aut Kaza, Ravi K. aut Francis, Isaac R. aut Ellis, James H. aut Wolf, J. Stuart aut Hafez, Khaled aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 39(2014), 3 vom: 18. Feb., Seite 533-542 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:39 year:2014 number:3 day:18 month:02 pages:533-542 https://dx.doi.org/10.1007/s00261-014-0088-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_150 GBV_ILN_2113 AR 39 2014 3 18 02 533-542 |
| allfields_unstemmed |
10.1007/s00261-014-0088-y doi (DE-627)SPR003192539 (SPR)s00261-014-0088-y-e DE-627 ger DE-627 rakwb eng Orton, Lorenzo P. verfasserin aut Variability in computed tomography diameter measurements of solid renal masses 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media New York 2014 Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. Renal mass measurements (dpeaa)DE-He213 Computed tomography (dpeaa)DE-He213 Solid renal mass (dpeaa)DE-He213 Cohan, Richard H. aut Davenport, Matthew S. aut Parker, Robert A. aut Parameswaran, Aishwarya aut Caoili, Elaine M. aut Kaza, Ravi K. aut Francis, Isaac R. aut Ellis, James H. aut Wolf, J. Stuart aut Hafez, Khaled aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 39(2014), 3 vom: 18. Feb., Seite 533-542 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:39 year:2014 number:3 day:18 month:02 pages:533-542 https://dx.doi.org/10.1007/s00261-014-0088-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_150 GBV_ILN_2113 AR 39 2014 3 18 02 533-542 |
| allfieldsGer |
10.1007/s00261-014-0088-y doi (DE-627)SPR003192539 (SPR)s00261-014-0088-y-e DE-627 ger DE-627 rakwb eng Orton, Lorenzo P. verfasserin aut Variability in computed tomography diameter measurements of solid renal masses 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media New York 2014 Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. Renal mass measurements (dpeaa)DE-He213 Computed tomography (dpeaa)DE-He213 Solid renal mass (dpeaa)DE-He213 Cohan, Richard H. aut Davenport, Matthew S. aut Parker, Robert A. aut Parameswaran, Aishwarya aut Caoili, Elaine M. aut Kaza, Ravi K. aut Francis, Isaac R. aut Ellis, James H. aut Wolf, J. Stuart aut Hafez, Khaled aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 39(2014), 3 vom: 18. Feb., Seite 533-542 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:39 year:2014 number:3 day:18 month:02 pages:533-542 https://dx.doi.org/10.1007/s00261-014-0088-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_150 GBV_ILN_2113 AR 39 2014 3 18 02 533-542 |
| allfieldsSound |
10.1007/s00261-014-0088-y doi (DE-627)SPR003192539 (SPR)s00261-014-0088-y-e DE-627 ger DE-627 rakwb eng Orton, Lorenzo P. verfasserin aut Variability in computed tomography diameter measurements of solid renal masses 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media New York 2014 Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. Renal mass measurements (dpeaa)DE-He213 Computed tomography (dpeaa)DE-He213 Solid renal mass (dpeaa)DE-He213 Cohan, Richard H. aut Davenport, Matthew S. aut Parker, Robert A. aut Parameswaran, Aishwarya aut Caoili, Elaine M. aut Kaza, Ravi K. aut Francis, Isaac R. aut Ellis, James H. aut Wolf, J. Stuart aut Hafez, Khaled aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 39(2014), 3 vom: 18. Feb., Seite 533-542 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:39 year:2014 number:3 day:18 month:02 pages:533-542 https://dx.doi.org/10.1007/s00261-014-0088-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_120 GBV_ILN_150 GBV_ILN_2113 AR 39 2014 3 18 02 533-542 |
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Enthalten in Abdominal radiology 39(2014), 3 vom: 18. Feb., Seite 533-542 volume:39 year:2014 number:3 day:18 month:02 pages:533-542 |
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Orton, Lorenzo P. @@aut@@ Cohan, Richard H. @@aut@@ Davenport, Matthew S. @@aut@@ Parker, Robert A. @@aut@@ Parameswaran, Aishwarya @@aut@@ Caoili, Elaine M. @@aut@@ Kaza, Ravi K. @@aut@@ Francis, Isaac R. @@aut@@ Ellis, James H. @@aut@@ Wolf, J. Stuart @@aut@@ Hafez, Khaled @@aut@@ |
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Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. 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Orton, Lorenzo P. misc Renal mass measurements misc Computed tomography misc Solid renal mass Variability in computed tomography diameter measurements of solid renal masses |
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Variability in computed tomography diameter measurements of solid renal masses |
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Orton, Lorenzo P. Cohan, Richard H. Davenport, Matthew S. Parker, Robert A. Parameswaran, Aishwarya Caoili, Elaine M. Kaza, Ravi K. Francis, Isaac R. Ellis, James H. Wolf, J. Stuart Hafez, Khaled |
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10.1007/s00261-014-0088-y |
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variability in computed tomography diameter measurements of solid renal masses |
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Variability in computed tomography diameter measurements of solid renal masses |
| abstract |
Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. © Springer Science+Business Media New York 2014 |
| abstractGer |
Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. © Springer Science+Business Media New York 2014 |
| abstract_unstemmed |
Purpose To determine whether the frequency of intra-observer measurement discrepancies ≥5 mm for solid renal masses varies by renal mass characteristics and CT contrast phase. Materials and methods This HIPAA-compliant retrospective study was approved by our IRB. We selected single CT images performed during the nephrographic phase (NP) of renal enhancement in 97 patients, each with a single solid renal mass. Mass location, margin, heterogeneity, and growth pattern were assessed. Six readers measured each mass on two occasions >3 weeks apart. Readers also measured the masses on images in 50 patients who had corticomedullary phase (CMP) images obtained during the same study. Results were assessed using Chi-square/Fisher’s exact and Wilcoxon Signed Rank tests, and logistic regression analyses. Results For NP to NP comparisons, intra-reader measurement differences ≥5 mm were seen for 3.7% (17/463) of masses <4 cm, but increased to 16.8% (20/119) for masses >4 cm (p < 0.0001). Masses with poorly defined margins (15.9% [22/138] vs. 3.4% [15/444] for well-defined margins, p < 0.0001) and heterogeneity (15.3% [22/144], vs. 5.0% [14/282] for minimally heterogeneous, vs. 0.6% [1/156] for homogeneous, p < 0.0001), were more frequently associated with measurement differences ≥5 mm. Differences ≥5 mm were more frequent when only CMP images were utilized (14% [42/299]), or when CMP images were compared with NP images (26% [77/299]). Conclusions A ≥5 mm intra-reader variation in measured size of solid renal masses <4 cm is uncommon for NP to NP comparisons. Variation increases when masses are ≥4 cm, poorly defined, or heterogeneous; or when CMP images are utilized. © Springer Science+Business Media New York 2014 |
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Variability in computed tomography diameter measurements of solid renal masses |
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Cohan, Richard H. Davenport, Matthew S. Parker, Robert A. Parameswaran, Aishwarya Caoili, Elaine M. Kaza, Ravi K. Francis, Isaac R. Ellis, James H. Wolf, J. Stuart Hafez, Khaled |
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