Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer

Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two diffe...
Ausführliche Beschreibung

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Autor*in:	Delli Pizzi, Andrea [verfasserIn] Caposiena, Daniele Mastrodicasa, Domenico Trebeschi, Stefano Lambregts, Doenja Rosa, Consuelo Cianci, Roberta Seccia, Barbara Sessa, Barbara Di Flamminio, Filippo Maria Chiacchiaretta, Piero Caravatta, Luciana Cinalli, Sebastiano Di Sebastiano, Pierluigi Caulo, Massimo Genovesi, Domenico Beets-Tan, Regina Basilico, Raffaella

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Rectal cancer Diffusion-weighted imaging Ultrahigh value b2000 Tumor conspicuity Tumor detectability Treatment response

Anmerkung:	© Springer Science+Business Media, LLC, part of Springer Nature 2019

Übergeordnetes Werk:	Enthalten in: Abdominal radiology - [Boston, MA] : Springer US, 2016, 44(2019), 11 vom: 09. Aug., Seite 3595-3605
Übergeordnetes Werk:	volume:44 ; year:2019 ; number:11 ; day:09 ; month:08 ; pages:3595-3605

Links:	Volltext

DOI / URN:	10.1007/s00261-019-02177-y

Katalog-ID:	SPR003209385

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100	1		\|a Delli Pizzi, Andrea \|e verfasserin \|0 (orcid)0000-0002-2011-3753 \|4 aut
245	1	0	\|a Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
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520			\|a Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000.
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700	1		\|a Caposiena, Daniele \|4 aut
700	1		\|a Mastrodicasa, Domenico \|4 aut
700	1		\|a Trebeschi, Stefano \|4 aut
700	1		\|a Lambregts, Doenja \|4 aut
700	1		\|a Rosa, Consuelo \|4 aut
700	1		\|a Cianci, Roberta \|4 aut
700	1		\|a Seccia, Barbara \|4 aut
700	1		\|a Sessa, Barbara \|4 aut
700	1		\|a Di Flamminio, Filippo Maria \|4 aut
700	1		\|a Chiacchiaretta, Piero \|4 aut
700	1		\|a Caravatta, Luciana \|4 aut
700	1		\|a Cinalli, Sebastiano \|4 aut
700	1		\|a Di Sebastiano, Pierluigi \|4 aut
700	1		\|a Caulo, Massimo \|4 aut
700	1		\|a Genovesi, Domenico \|4 aut
700	1		\|a Beets-Tan, Regina \|4 aut
700	1		\|a Basilico, Raffaella \|4 aut
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allfields	10.1007/s00261-019-02177-y doi (DE-627)SPR003209385 (SPR)s00261-019-02177-y-e DE-627 ger DE-627 rakwb eng Delli Pizzi, Andrea verfasserin (orcid)0000-0002-2011-3753 aut Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213 Caposiena, Daniele aut Mastrodicasa, Domenico aut Trebeschi, Stefano aut Lambregts, Doenja aut Rosa, Consuelo aut Cianci, Roberta aut Seccia, Barbara aut Sessa, Barbara aut Di Flamminio, Filippo Maria aut Chiacchiaretta, Piero aut Caravatta, Luciana aut Cinalli, Sebastiano aut Di Sebastiano, Pierluigi aut Caulo, Massimo aut Genovesi, Domenico aut Beets-Tan, Regina aut Basilico, Raffaella aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 44(2019), 11 vom: 09. Aug., Seite 3595-3605 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605 https://dx.doi.org/10.1007/s00261-019-02177-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2019 11 09 08 3595-3605
spelling	10.1007/s00261-019-02177-y doi (DE-627)SPR003209385 (SPR)s00261-019-02177-y-e DE-627 ger DE-627 rakwb eng Delli Pizzi, Andrea verfasserin (orcid)0000-0002-2011-3753 aut Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213 Caposiena, Daniele aut Mastrodicasa, Domenico aut Trebeschi, Stefano aut Lambregts, Doenja aut Rosa, Consuelo aut Cianci, Roberta aut Seccia, Barbara aut Sessa, Barbara aut Di Flamminio, Filippo Maria aut Chiacchiaretta, Piero aut Caravatta, Luciana aut Cinalli, Sebastiano aut Di Sebastiano, Pierluigi aut Caulo, Massimo aut Genovesi, Domenico aut Beets-Tan, Regina aut Basilico, Raffaella aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 44(2019), 11 vom: 09. Aug., Seite 3595-3605 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605 https://dx.doi.org/10.1007/s00261-019-02177-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2019 11 09 08 3595-3605
allfields_unstemmed	10.1007/s00261-019-02177-y doi (DE-627)SPR003209385 (SPR)s00261-019-02177-y-e DE-627 ger DE-627 rakwb eng Delli Pizzi, Andrea verfasserin (orcid)0000-0002-2011-3753 aut Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213 Caposiena, Daniele aut Mastrodicasa, Domenico aut Trebeschi, Stefano aut Lambregts, Doenja aut Rosa, Consuelo aut Cianci, Roberta aut Seccia, Barbara aut Sessa, Barbara aut Di Flamminio, Filippo Maria aut Chiacchiaretta, Piero aut Caravatta, Luciana aut Cinalli, Sebastiano aut Di Sebastiano, Pierluigi aut Caulo, Massimo aut Genovesi, Domenico aut Beets-Tan, Regina aut Basilico, Raffaella aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 44(2019), 11 vom: 09. Aug., Seite 3595-3605 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605 https://dx.doi.org/10.1007/s00261-019-02177-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2019 11 09 08 3595-3605
allfieldsGer	10.1007/s00261-019-02177-y doi (DE-627)SPR003209385 (SPR)s00261-019-02177-y-e DE-627 ger DE-627 rakwb eng Delli Pizzi, Andrea verfasserin (orcid)0000-0002-2011-3753 aut Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213 Caposiena, Daniele aut Mastrodicasa, Domenico aut Trebeschi, Stefano aut Lambregts, Doenja aut Rosa, Consuelo aut Cianci, Roberta aut Seccia, Barbara aut Sessa, Barbara aut Di Flamminio, Filippo Maria aut Chiacchiaretta, Piero aut Caravatta, Luciana aut Cinalli, Sebastiano aut Di Sebastiano, Pierluigi aut Caulo, Massimo aut Genovesi, Domenico aut Beets-Tan, Regina aut Basilico, Raffaella aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 44(2019), 11 vom: 09. Aug., Seite 3595-3605 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605 https://dx.doi.org/10.1007/s00261-019-02177-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2019 11 09 08 3595-3605
allfieldsSound	10.1007/s00261-019-02177-y doi (DE-627)SPR003209385 (SPR)s00261-019-02177-y-e DE-627 ger DE-627 rakwb eng Delli Pizzi, Andrea verfasserin (orcid)0000-0002-2011-3753 aut Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer Science+Business Media, LLC, part of Springer Nature 2019 Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213 Caposiena, Daniele aut Mastrodicasa, Domenico aut Trebeschi, Stefano aut Lambregts, Doenja aut Rosa, Consuelo aut Cianci, Roberta aut Seccia, Barbara aut Sessa, Barbara aut Di Flamminio, Filippo Maria aut Chiacchiaretta, Piero aut Caravatta, Luciana aut Cinalli, Sebastiano aut Di Sebastiano, Pierluigi aut Caulo, Massimo aut Genovesi, Domenico aut Beets-Tan, Regina aut Basilico, Raffaella aut Enthalten in Abdominal radiology [Boston, MA] : Springer US, 2016 44(2019), 11 vom: 09. Aug., Seite 3595-3605 (DE-627)847023133 (DE-600)2845742-0 2366-0058 nnns volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605 https://dx.doi.org/10.1007/s00261-019-02177-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 44 2019 11 09 08 3595-3605
language	English
source	Enthalten in Abdominal radiology 44(2019), 11 vom: 09. Aug., Seite 3595-3605 volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605
sourceStr	Enthalten in Abdominal radiology 44(2019), 11 vom: 09. Aug., Seite 3595-3605 volume:44 year:2019 number:11 day:09 month:08 pages:3595-3605
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Rectal cancer Diffusion-weighted imaging Ultrahigh value b2000 Tumor conspicuity Tumor detectability Treatment response
isfreeaccess_bool	false
container_title	Abdominal radiology
authorswithroles_txt_mv	Delli Pizzi, Andrea @@aut@@ Caposiena, Daniele @@aut@@ Mastrodicasa, Domenico @@aut@@ Trebeschi, Stefano @@aut@@ Lambregts, Doenja @@aut@@ Rosa, Consuelo @@aut@@ Cianci, Roberta @@aut@@ Seccia, Barbara @@aut@@ Sessa, Barbara @@aut@@ Di Flamminio, Filippo Maria @@aut@@ Chiacchiaretta, Piero @@aut@@ Caravatta, Luciana @@aut@@ Cinalli, Sebastiano @@aut@@ Di Sebastiano, Pierluigi @@aut@@ Caulo, Massimo @@aut@@ Genovesi, Domenico @@aut@@ Beets-Tan, Regina @@aut@@ Basilico, Raffaella @@aut@@
publishDateDaySort_date	2019-08-09T00:00:00Z
hierarchy_top_id	847023133
id	SPR003209385
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003209385</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520002608.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2019 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00261-019-02177-y</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003209385</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00261-019-02177-y-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Delli Pizzi, Andrea</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(orcid)0000-0002-2011-3753</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer Science+Business Media, LLC, part of Springer Nature 2019</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Rectal cancer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Diffusion-weighted imaging</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ultrahigh</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">value</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">b2000</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tumor conspicuity</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tumor detectability</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Treatment response</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Caposiena, Daniele</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mastrodicasa, Domenico</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Trebeschi, Stefano</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lambregts, Doenja</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rosa, Consuelo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cianci, Roberta</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Seccia, Barbara</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sessa, Barbara</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Di Flamminio, Filippo Maria</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chiacchiaretta, Piero</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Caravatta, Luciana</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cinalli, Sebastiano</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Di Sebastiano, Pierluigi</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Caulo, Massimo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Genovesi, Domenico</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Beets-Tan, Regina</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Basilico, Raffaella</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Abdominal radiology</subfield><subfield code="d">[Boston, MA] : Springer US, 2016</subfield><subfield code="g">44(2019), 11 vom: 09. 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author	Delli Pizzi, Andrea
spellingShingle	Delli Pizzi, Andrea misc Rectal cancer misc Diffusion-weighted imaging misc Ultrahigh misc value misc b2000 misc Tumor conspicuity misc Tumor detectability misc Treatment response Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
authorStr	Delli Pizzi, Andrea
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issn	2366-0058
topic_title	Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer Rectal cancer (dpeaa)DE-He213 Diffusion-weighted imaging (dpeaa)DE-He213 Ultrahigh (dpeaa)DE-He213 value (dpeaa)DE-He213 b2000 (dpeaa)DE-He213 Tumor conspicuity (dpeaa)DE-He213 Tumor detectability (dpeaa)DE-He213 Treatment response (dpeaa)DE-He213
topic	misc Rectal cancer misc Diffusion-weighted imaging misc Ultrahigh misc value misc b2000 misc Tumor conspicuity misc Tumor detectability misc Treatment response
topic_unstemmed	misc Rectal cancer misc Diffusion-weighted imaging misc Ultrahigh misc value misc b2000 misc Tumor conspicuity misc Tumor detectability misc Treatment response
topic_browse	misc Rectal cancer misc Diffusion-weighted imaging misc Ultrahigh misc value misc b2000 misc Tumor conspicuity misc Tumor detectability misc Treatment response
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title	Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
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title_full	Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
author_sort	Delli Pizzi, Andrea
journal	Abdominal radiology
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author_browse	Delli Pizzi, Andrea Caposiena, Daniele Mastrodicasa, Domenico Trebeschi, Stefano Lambregts, Doenja Rosa, Consuelo Cianci, Roberta Seccia, Barbara Sessa, Barbara Di Flamminio, Filippo Maria Chiacchiaretta, Piero Caravatta, Luciana Cinalli, Sebastiano Di Sebastiano, Pierluigi Caulo, Massimo Genovesi, Domenico Beets-Tan, Regina Basilico, Raffaella
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author-letter	Delli Pizzi, Andrea
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title_sort	tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
title_auth	Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
abstract	Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. © Springer Science+Business Media, LLC, part of Springer Nature 2019
abstractGer	Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. © Springer Science+Business Media, LLC, part of Springer Nature 2019
abstract_unstemmed	Purpose To compare tumor detectability and conspicuity of standard b = 1000 s/$ mm^{2} $ (b1000) versus ultrahigh b = 2000 s/$ mm^{2} $ (b2000) diffusion-weighted imaging (DWI) in rectal cancer. Methods Fifty-five patients for a total of 81 3T DWI-MR scans were retrospectively evaluated by two differently experienced readers. A comparison between b1000 and b2000 for tumor detectability and conspicuity was performed. The conspicuity was qualitatively and quantitatively assessed by using three-point scale and whole tumor volume manual delineation, respectively. Receiver-operating characteristic curve (ROC) with area under the curve (AUC) analysis provided diagnostic accuracy in tumor detectability of restaging MR scans. Qualitative scores and quantitative features including mean signal intensity, variance, 10th percentile and 90th percentile, were compared using the Wilcoxon test. Interobserver agreement (IOA) for qualitative and quantitative data was calculated using Cohen’s Kappa and intraclass correlation coefficient (ICC) respectively. Results Diagnostic accuracy was comparable between b1000 and b2000 for both readers (p > 0.05). Overall quality scores were significantly better for b2000 than b1000 (2.29 vs 1.65 Reader 1, p = 0.01; 2.18 vs 1.69 Reader 2, p = 0.04). IOA was equally good for both b values (k = 0.86 b1000, k = 0.86 b2000). Quantitative analysis revealed more uniform signal (measured in variance) of b2000 in both healthy surrounding tissue (p < 0.05) and tumor (p < 0.05), with less outliers (measured using 10th and 90th percentile). Additionally, b2000 offered lower mean signal intensity in tissue sorrounding the tumor (p < 0.05). Finally, ICC improved from 0.92 (b1000) to 0.97 (b2000). Conclusion Ultrahigh b value (b2000) may improve rectal cancer conspicuity and introbserver agreement maintaining comparable diagnostic accuracy to standard b1000. © Springer Science+Business Media, LLC, part of Springer Nature 2019
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title_short	Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer
url	https://dx.doi.org/10.1007/s00261-019-02177-y
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author2	Caposiena, Daniele Mastrodicasa, Domenico Trebeschi, Stefano Lambregts, Doenja Rosa, Consuelo Cianci, Roberta Seccia, Barbara Sessa, Barbara Di Flamminio, Filippo Maria Chiacchiaretta, Piero Caravatta, Luciana Cinalli, Sebastiano Di Sebastiano, Pierluigi Caulo, Massimo Genovesi, Domenico Beets-Tan, Regina Basilico, Raffaella
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up_date	2024-07-03T18:00:14.474Z
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Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer

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