Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx
Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Lefebvre, Jean Louis [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2003 |
|---|
| Schlagwörter: |
|---|
| Anmerkung: |
© Société Internationale de Chirurgie 2003 |
|---|
| Übergeordnetes Werk: |
Enthalten in: World Journal of Surgery - Springer-Verlag, 1996, 27(2003), 7 vom: 28. Mai, Seite 811-816 |
|---|---|
| Übergeordnetes Werk: |
volume:27 ; year:2003 ; number:7 ; day:28 ; month:05 ; pages:811-816 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00268-003-7106-5 |
|---|
| Katalog-ID: |
SPR003399060 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR003399060 | ||
| 003 | DE-627 | ||
| 005 | 20230520010243.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201001s2003 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00268-003-7106-5 |2 doi | |
| 035 | |a (DE-627)SPR003399060 | ||
| 035 | |a (SPR)s00268-003-7106-5-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lefebvre, Jean Louis |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| 264 | 1 | |c 2003 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © Société Internationale de Chirurgie 2003 | ||
| 520 | |a Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. | ||
| 650 | 4 | |a Laryngeal Cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Total Laryngectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Hypopharyngeal Cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Glottic Carcinoma |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Laryngeal Function |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Lartigau, Eric |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t World Journal of Surgery |d Springer-Verlag, 1996 |g 27(2003), 7 vom: 28. Mai, Seite 811-816 |w (DE-627)SPR003391159 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:2003 |g number:7 |g day:28 |g month:05 |g pages:811-816 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s00268-003-7106-5 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 912 | |a SSG-OLC-PHA | ||
| 951 | |a AR | ||
| 952 | |d 27 |j 2003 |e 7 |b 28 |c 05 |h 811-816 | ||
| author_variant |
j l l jl jll e l el |
|---|---|
| matchkey_str |
lefebvrejeanlouislartigaueric:2003----:rsrainfomnfntodrnmngmnocneot |
| hierarchy_sort_str |
2003 |
| publishDate |
2003 |
| allfields |
10.1007/s00268-003-7106-5 doi (DE-627)SPR003399060 (SPR)s00268-003-7106-5-e DE-627 ger DE-627 rakwb eng Lefebvre, Jean Louis verfasserin aut Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx 2003 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2003 Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 Lartigau, Eric aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 27(2003), 7 vom: 28. Mai, Seite 811-816 (DE-627)SPR003391159 nnns volume:27 year:2003 number:7 day:28 month:05 pages:811-816 https://dx.doi.org/10.1007/s00268-003-7106-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 27 2003 7 28 05 811-816 |
| spelling |
10.1007/s00268-003-7106-5 doi (DE-627)SPR003399060 (SPR)s00268-003-7106-5-e DE-627 ger DE-627 rakwb eng Lefebvre, Jean Louis verfasserin aut Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx 2003 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2003 Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 Lartigau, Eric aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 27(2003), 7 vom: 28. Mai, Seite 811-816 (DE-627)SPR003391159 nnns volume:27 year:2003 number:7 day:28 month:05 pages:811-816 https://dx.doi.org/10.1007/s00268-003-7106-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 27 2003 7 28 05 811-816 |
| allfields_unstemmed |
10.1007/s00268-003-7106-5 doi (DE-627)SPR003399060 (SPR)s00268-003-7106-5-e DE-627 ger DE-627 rakwb eng Lefebvre, Jean Louis verfasserin aut Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx 2003 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2003 Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 Lartigau, Eric aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 27(2003), 7 vom: 28. Mai, Seite 811-816 (DE-627)SPR003391159 nnns volume:27 year:2003 number:7 day:28 month:05 pages:811-816 https://dx.doi.org/10.1007/s00268-003-7106-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 27 2003 7 28 05 811-816 |
| allfieldsGer |
10.1007/s00268-003-7106-5 doi (DE-627)SPR003399060 (SPR)s00268-003-7106-5-e DE-627 ger DE-627 rakwb eng Lefebvre, Jean Louis verfasserin aut Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx 2003 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2003 Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 Lartigau, Eric aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 27(2003), 7 vom: 28. Mai, Seite 811-816 (DE-627)SPR003391159 nnns volume:27 year:2003 number:7 day:28 month:05 pages:811-816 https://dx.doi.org/10.1007/s00268-003-7106-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 27 2003 7 28 05 811-816 |
| allfieldsSound |
10.1007/s00268-003-7106-5 doi (DE-627)SPR003399060 (SPR)s00268-003-7106-5-e DE-627 ger DE-627 rakwb eng Lefebvre, Jean Louis verfasserin aut Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx 2003 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2003 Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 Lartigau, Eric aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 27(2003), 7 vom: 28. Mai, Seite 811-816 (DE-627)SPR003391159 nnns volume:27 year:2003 number:7 day:28 month:05 pages:811-816 https://dx.doi.org/10.1007/s00268-003-7106-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 27 2003 7 28 05 811-816 |
| language |
English |
| source |
Enthalten in World Journal of Surgery 27(2003), 7 vom: 28. Mai, Seite 811-816 volume:27 year:2003 number:7 day:28 month:05 pages:811-816 |
| sourceStr |
Enthalten in World Journal of Surgery 27(2003), 7 vom: 28. Mai, Seite 811-816 volume:27 year:2003 number:7 day:28 month:05 pages:811-816 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Laryngeal Cancer Total Laryngectomy Hypopharyngeal Cancer Glottic Carcinoma Laryngeal Function |
| isfreeaccess_bool |
false |
| container_title |
World Journal of Surgery |
| authorswithroles_txt_mv |
Lefebvre, Jean Louis @@aut@@ Lartigau, Eric @@aut@@ |
| publishDateDaySort_date |
2003-05-28T00:00:00Z |
| hierarchy_top_id |
SPR003391159 |
| id |
SPR003399060 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003399060</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520010243.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2003 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-003-7106-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003399060</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-003-7106-5-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Lefebvre, Jean Louis</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2003</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laryngeal Cancer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Total Laryngectomy</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypopharyngeal Cancer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Glottic Carcinoma</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laryngeal Function</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lartigau, Eric</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">27(2003), 7 vom: 28. Mai, Seite 811-816</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:27</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:7</subfield><subfield code="g">day:28</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:811-816</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-003-7106-5</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">27</subfield><subfield code="j">2003</subfield><subfield code="e">7</subfield><subfield code="b">28</subfield><subfield code="c">05</subfield><subfield code="h">811-816</subfield></datafield></record></collection>
|
| author |
Lefebvre, Jean Louis |
| spellingShingle |
Lefebvre, Jean Louis misc Laryngeal Cancer misc Total Laryngectomy misc Hypopharyngeal Cancer misc Glottic Carcinoma misc Laryngeal Function Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| authorStr |
Lefebvre, Jean Louis |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)SPR003391159 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut |
| collection |
springer |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx Laryngeal Cancer (dpeaa)DE-He213 Total Laryngectomy (dpeaa)DE-He213 Hypopharyngeal Cancer (dpeaa)DE-He213 Glottic Carcinoma (dpeaa)DE-He213 Laryngeal Function (dpeaa)DE-He213 |
| topic |
misc Laryngeal Cancer misc Total Laryngectomy misc Hypopharyngeal Cancer misc Glottic Carcinoma misc Laryngeal Function |
| topic_unstemmed |
misc Laryngeal Cancer misc Total Laryngectomy misc Hypopharyngeal Cancer misc Glottic Carcinoma misc Laryngeal Function |
| topic_browse |
misc Laryngeal Cancer misc Total Laryngectomy misc Hypopharyngeal Cancer misc Glottic Carcinoma misc Laryngeal Function |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
World Journal of Surgery |
| hierarchy_parent_id |
SPR003391159 |
| hierarchy_top_title |
World Journal of Surgery |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)SPR003391159 |
| title |
Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| ctrlnum |
(DE-627)SPR003399060 (SPR)s00268-003-7106-5-e |
| title_full |
Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| author_sort |
Lefebvre, Jean Louis |
| journal |
World Journal of Surgery |
| journalStr |
World Journal of Surgery |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2003 |
| contenttype_str_mv |
txt |
| container_start_page |
811 |
| author_browse |
Lefebvre, Jean Louis Lartigau, Eric |
| container_volume |
27 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Lefebvre, Jean Louis |
| doi_str_mv |
10.1007/s00268-003-7106-5 |
| title_sort |
preservation of form and function during management of cancer of the larynx and hypopharynx |
| title_auth |
Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| abstract |
Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. © Société Internationale de Chirurgie 2003 |
| abstractGer |
Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. © Société Internationale de Chirurgie 2003 |
| abstract_unstemmed |
Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible. © Société Internationale de Chirurgie 2003 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA |
| container_issue |
7 |
| title_short |
Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx |
| url |
https://dx.doi.org/10.1007/s00268-003-7106-5 |
| remote_bool |
true |
| author2 |
Lartigau, Eric |
| author2Str |
Lartigau, Eric |
| ppnlink |
SPR003391159 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00268-003-7106-5 |
| up_date |
2024-07-03T19:18:55.186Z |
| _version_ |
1803586723054092288 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003399060</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230520010243.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2003 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-003-7106-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003399060</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-003-7106-5-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Lefebvre, Jean Louis</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Preservation of Form and Function during Management of Cancer of the Larynx and Hypopharynx</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2003</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2003</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract The treatment of laryngeal and hypopharyngeal cancer has seen notable changes during the twentieth century. Intensive surgical research has allowed laryngologists to deal with almost any local extension and to propose an appropriate surgical procedure for each case. This surgery is able to control the disease in most patients locally but is limited in its indications (resectable diseases and operable patients). On the other hand, radiotherapy has been impressively improved (dosimetry, definition of target volume) and has become an indisputable alternative to surgery. The two approaches are comparable in terms of local control and functional results when dealing with early disease. For advanced disease, however, the debate is open between surgery, which is more efficient but mutilating, and radiotherapy, which can preserve the larynx in many instances even though it requires sometimes mutilating surgery for salvage. The appearance of platinum-based chemotherapy has updated this discussion. To date, most of the randomized comparisons of mutilating/nonmutilating approaches have been with induction chemotherapy followed by irradiation if there has been a good clinical response to the chemotherapy. There are other options as well that deserve evaluation (e.g., radiotherapy with altered fractionation or with concurrent chemotherapy), although surgery still seems to be indicated in certain cases. Finally, efforts should be made to select patients properly (based on tumor characteristics, clinical aspects, imaging, and biology) for the various strategies with the primary goal of curing the patient and secondarily to preserve laryngeal form and function when possible.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laryngeal Cancer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Total Laryngectomy</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hypopharyngeal Cancer</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Glottic Carcinoma</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Laryngeal Function</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lartigau, Eric</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">27(2003), 7 vom: 28. Mai, Seite 811-816</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:27</subfield><subfield code="g">year:2003</subfield><subfield code="g">number:7</subfield><subfield code="g">day:28</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:811-816</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-003-7106-5</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">27</subfield><subfield code="j">2003</subfield><subfield code="e">7</subfield><subfield code="b">28</subfield><subfield code="c">05</subfield><subfield code="h">811-816</subfield></datafield></record></collection>
|
| score |
7.3989096 |