Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B
Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or high...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nakahara, Hideki [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2005 |
|---|
| Schlagwörter: |
Orthotopic Liver Transplantation |
|---|
| Anmerkung: |
© Société Internationale de Chirurgie 2005 |
|---|
| Übergeordnetes Werk: |
Enthalten in: World Journal of Surgery - Springer-Verlag, 1996, 29(2005), 6 vom: 12. Mai, Seite 734-738 |
|---|---|
| Übergeordnetes Werk: |
volume:29 ; year:2005 ; number:6 ; day:12 ; month:05 ; pages:734-738 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00268-005-7750-z |
|---|
| Katalog-ID: |
SPR003404730 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR003404730 | ||
| 003 | DE-627 | ||
| 005 | 20230328135919.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201001s2005 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00268-005-7750-z |2 doi | |
| 035 | |a (DE-627)SPR003404730 | ||
| 035 | |a (SPR)s00268-005-7750-z-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Nakahara, Hideki |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| 264 | 1 | |c 2005 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © Société Internationale de Chirurgie 2005 | ||
| 520 | |a Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. | ||
| 650 | 4 | |a Orthotopic Liver Transplantation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Partial Hepatectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Esophageal Varix |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Transcatheter Arterial Embolization |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Percutaneous Ethanol Injection |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Itamoto, Toshiyuki |4 aut | |
| 700 | 1 | |a Katayama, Koji |4 aut | |
| 700 | 1 | |a Ohdan, Hideki |4 aut | |
| 700 | 1 | |a Hino, Hiroshi |4 aut | |
| 700 | 1 | |a Ochi, Makoto |4 aut | |
| 700 | 1 | |a Tashiro, Hirotaka |4 aut | |
| 700 | 1 | |a Asahara, Toshimasa |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t World Journal of Surgery |d Springer-Verlag, 1996 |g 29(2005), 6 vom: 12. Mai, Seite 734-738 |w (DE-627)SPR003391159 |7 nnns |
| 773 | 1 | 8 | |g volume:29 |g year:2005 |g number:6 |g day:12 |g month:05 |g pages:734-738 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s00268-005-7750-z |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 951 | |a AR | ||
| 952 | |d 29 |j 2005 |e 6 |b 12 |c 05 |h 734-738 | ||
| author_variant |
h n hn t i ti k k kk h o ho h h hh m o mo h t ht t a ta |
|---|---|
| matchkey_str |
nakaharahidekiitamototoshiyukikatayamako:2005----:niainfeaetmfriroiptetwthptcluacrioal |
| hierarchy_sort_str |
2005 |
| publishDate |
2005 |
| allfields |
10.1007/s00268-005-7750-z doi (DE-627)SPR003404730 (SPR)s00268-005-7750-z-e DE-627 ger DE-627 rakwb eng Nakahara, Hideki verfasserin aut Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2005 Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 Itamoto, Toshiyuki aut Katayama, Koji aut Ohdan, Hideki aut Hino, Hiroshi aut Ochi, Makoto aut Tashiro, Hirotaka aut Asahara, Toshimasa aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 29(2005), 6 vom: 12. Mai, Seite 734-738 (DE-627)SPR003391159 nnns volume:29 year:2005 number:6 day:12 month:05 pages:734-738 https://dx.doi.org/10.1007/s00268-005-7750-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 29 2005 6 12 05 734-738 |
| spelling |
10.1007/s00268-005-7750-z doi (DE-627)SPR003404730 (SPR)s00268-005-7750-z-e DE-627 ger DE-627 rakwb eng Nakahara, Hideki verfasserin aut Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2005 Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 Itamoto, Toshiyuki aut Katayama, Koji aut Ohdan, Hideki aut Hino, Hiroshi aut Ochi, Makoto aut Tashiro, Hirotaka aut Asahara, Toshimasa aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 29(2005), 6 vom: 12. Mai, Seite 734-738 (DE-627)SPR003391159 nnns volume:29 year:2005 number:6 day:12 month:05 pages:734-738 https://dx.doi.org/10.1007/s00268-005-7750-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 29 2005 6 12 05 734-738 |
| allfields_unstemmed |
10.1007/s00268-005-7750-z doi (DE-627)SPR003404730 (SPR)s00268-005-7750-z-e DE-627 ger DE-627 rakwb eng Nakahara, Hideki verfasserin aut Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2005 Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 Itamoto, Toshiyuki aut Katayama, Koji aut Ohdan, Hideki aut Hino, Hiroshi aut Ochi, Makoto aut Tashiro, Hirotaka aut Asahara, Toshimasa aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 29(2005), 6 vom: 12. Mai, Seite 734-738 (DE-627)SPR003391159 nnns volume:29 year:2005 number:6 day:12 month:05 pages:734-738 https://dx.doi.org/10.1007/s00268-005-7750-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 29 2005 6 12 05 734-738 |
| allfieldsGer |
10.1007/s00268-005-7750-z doi (DE-627)SPR003404730 (SPR)s00268-005-7750-z-e DE-627 ger DE-627 rakwb eng Nakahara, Hideki verfasserin aut Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2005 Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 Itamoto, Toshiyuki aut Katayama, Koji aut Ohdan, Hideki aut Hino, Hiroshi aut Ochi, Makoto aut Tashiro, Hirotaka aut Asahara, Toshimasa aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 29(2005), 6 vom: 12. Mai, Seite 734-738 (DE-627)SPR003391159 nnns volume:29 year:2005 number:6 day:12 month:05 pages:734-738 https://dx.doi.org/10.1007/s00268-005-7750-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 29 2005 6 12 05 734-738 |
| allfieldsSound |
10.1007/s00268-005-7750-z doi (DE-627)SPR003404730 (SPR)s00268-005-7750-z-e DE-627 ger DE-627 rakwb eng Nakahara, Hideki verfasserin aut Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B 2005 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2005 Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 Itamoto, Toshiyuki aut Katayama, Koji aut Ohdan, Hideki aut Hino, Hiroshi aut Ochi, Makoto aut Tashiro, Hirotaka aut Asahara, Toshimasa aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 29(2005), 6 vom: 12. Mai, Seite 734-738 (DE-627)SPR003391159 nnns volume:29 year:2005 number:6 day:12 month:05 pages:734-738 https://dx.doi.org/10.1007/s00268-005-7750-z lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 29 2005 6 12 05 734-738 |
| language |
English |
| source |
Enthalten in World Journal of Surgery 29(2005), 6 vom: 12. Mai, Seite 734-738 volume:29 year:2005 number:6 day:12 month:05 pages:734-738 |
| sourceStr |
Enthalten in World Journal of Surgery 29(2005), 6 vom: 12. Mai, Seite 734-738 volume:29 year:2005 number:6 day:12 month:05 pages:734-738 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Orthotopic Liver Transplantation Partial Hepatectomy Esophageal Varix Transcatheter Arterial Embolization Percutaneous Ethanol Injection |
| isfreeaccess_bool |
false |
| container_title |
World Journal of Surgery |
| authorswithroles_txt_mv |
Nakahara, Hideki @@aut@@ Itamoto, Toshiyuki @@aut@@ Katayama, Koji @@aut@@ Ohdan, Hideki @@aut@@ Hino, Hiroshi @@aut@@ Ochi, Makoto @@aut@@ Tashiro, Hirotaka @@aut@@ Asahara, Toshimasa @@aut@@ |
| publishDateDaySort_date |
2005-05-12T00:00:00Z |
| hierarchy_top_id |
SPR003391159 |
| id |
SPR003404730 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003404730</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230328135919.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2005 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-005-7750-z</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003404730</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-005-7750-z-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Nakahara, Hideki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2005</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2005</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Orthotopic Liver Transplantation</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Partial Hepatectomy</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Esophageal Varix</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transcatheter Arterial Embolization</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Percutaneous Ethanol Injection</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Itamoto, Toshiyuki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Katayama, Koji</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohdan, Hideki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hino, Hiroshi</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ochi, Makoto</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tashiro, Hirotaka</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Asahara, Toshimasa</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">29(2005), 6 vom: 12. Mai, Seite 734-738</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:29</subfield><subfield code="g">year:2005</subfield><subfield code="g">number:6</subfield><subfield code="g">day:12</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:734-738</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-005-7750-z</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">29</subfield><subfield code="j">2005</subfield><subfield code="e">6</subfield><subfield code="b">12</subfield><subfield code="c">05</subfield><subfield code="h">734-738</subfield></datafield></record></collection>
|
| author |
Nakahara, Hideki |
| spellingShingle |
Nakahara, Hideki misc Orthotopic Liver Transplantation misc Partial Hepatectomy misc Esophageal Varix misc Transcatheter Arterial Embolization misc Percutaneous Ethanol Injection Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| authorStr |
Nakahara, Hideki |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)SPR003391159 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut |
| collection |
springer |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B Orthotopic Liver Transplantation (dpeaa)DE-He213 Partial Hepatectomy (dpeaa)DE-He213 Esophageal Varix (dpeaa)DE-He213 Transcatheter Arterial Embolization (dpeaa)DE-He213 Percutaneous Ethanol Injection (dpeaa)DE-He213 |
| topic |
misc Orthotopic Liver Transplantation misc Partial Hepatectomy misc Esophageal Varix misc Transcatheter Arterial Embolization misc Percutaneous Ethanol Injection |
| topic_unstemmed |
misc Orthotopic Liver Transplantation misc Partial Hepatectomy misc Esophageal Varix misc Transcatheter Arterial Embolization misc Percutaneous Ethanol Injection |
| topic_browse |
misc Orthotopic Liver Transplantation misc Partial Hepatectomy misc Esophageal Varix misc Transcatheter Arterial Embolization misc Percutaneous Ethanol Injection |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
World Journal of Surgery |
| hierarchy_parent_id |
SPR003391159 |
| hierarchy_top_title |
World Journal of Surgery |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)SPR003391159 |
| title |
Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| ctrlnum |
(DE-627)SPR003404730 (SPR)s00268-005-7750-z-e |
| title_full |
Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| author_sort |
Nakahara, Hideki |
| journal |
World Journal of Surgery |
| journalStr |
World Journal of Surgery |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2005 |
| contenttype_str_mv |
txt |
| container_start_page |
734 |
| author_browse |
Nakahara, Hideki Itamoto, Toshiyuki Katayama, Koji Ohdan, Hideki Hino, Hiroshi Ochi, Makoto Tashiro, Hirotaka Asahara, Toshimasa |
| container_volume |
29 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Nakahara, Hideki |
| doi_str_mv |
10.1007/s00268-005-7750-z |
| title_sort |
indication of hepatectomy for cirrhotic patients with hepatocellular carcinoma classified as child-pugh class b |
| title_auth |
Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| abstract |
Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. © Société Internationale de Chirurgie 2005 |
| abstractGer |
Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. © Société Internationale de Chirurgie 2005 |
| abstract_unstemmed |
Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors. © Société Internationale de Chirurgie 2005 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER |
| container_issue |
6 |
| title_short |
Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B |
| url |
https://dx.doi.org/10.1007/s00268-005-7750-z |
| remote_bool |
true |
| author2 |
Itamoto, Toshiyuki Katayama, Koji Ohdan, Hideki Hino, Hiroshi Ochi, Makoto Tashiro, Hirotaka Asahara, Toshimasa |
| author2Str |
Itamoto, Toshiyuki Katayama, Koji Ohdan, Hideki Hino, Hiroshi Ochi, Makoto Tashiro, Hirotaka Asahara, Toshimasa |
| ppnlink |
SPR003391159 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00268-005-7750-z |
| up_date |
2024-07-03T19:20:24.881Z |
| _version_ |
1803586817115553792 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003404730</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230328135919.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2005 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-005-7750-z</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003404730</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-005-7750-z-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Nakahara, Hideki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Indication of Hepatectomy for Cirrhotic Patients with Hepatocellular Carcinoma Classified as Child-Pugh Class B</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2005</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2005</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract We clarified the indication of partial hepatectomy in hepatocellular carcinoma (HCC) patients with liver cirrhosis classified as Child-Pugh class B. Univariate analysis revealed that adverse prognostic factors were (1) the presence of ascites, (2) elevated total bilirubin (1.5 mg/dl or higher), (3) reduced choline esterase (160 IU/ or lower), (4) elevated alpha-fetoprotein (AFP) (400 ng/ml or higher), (5) microscopic vascular invasion, and (6) non-curative hepatectomy. Microvascular invasion was excluded in the multivariate analysis because this factor could not be predicted before hepatectomy. Multivariate analysis revealed that independent adverse prognostic factors were (1) elevated total bilirubin (1.5 mg/dl or higher), (2) presence of ascites, (3) elevated AFP (400 ng/ml or higher), and (4) non-curative hepatectomy. The overall 5-year survival rate of patients with none of or only one of the four adverse prognostic factors was 45.8%. The overall 5-year survival rate of patients with two or more adverse prognostic factors was only 7.0%. Partial hepatectomy is the first choice of treatment for patients with none of or only one of the four adverse prognostic factors, whereas orthotopic liver transplantation or other conservative treatment should be considered for patients with two or more adverse prognostic factors.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Orthotopic Liver Transplantation</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Partial Hepatectomy</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Esophageal Varix</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transcatheter Arterial Embolization</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Percutaneous Ethanol Injection</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Itamoto, Toshiyuki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Katayama, Koji</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohdan, Hideki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hino, Hiroshi</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ochi, Makoto</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tashiro, Hirotaka</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Asahara, Toshimasa</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">29(2005), 6 vom: 12. Mai, Seite 734-738</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:29</subfield><subfield code="g">year:2005</subfield><subfield code="g">number:6</subfield><subfield code="g">day:12</subfield><subfield code="g">month:05</subfield><subfield code="g">pages:734-738</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-005-7750-z</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">29</subfield><subfield code="j">2005</subfield><subfield code="e">6</subfield><subfield code="b">12</subfield><subfield code="c">05</subfield><subfield code="h">734-738</subfield></datafield></record></collection>
|
| score |
7.3988447 |