Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction
Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective stud...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ibarra-Hurtado, Tomas R. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2009 |
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| Schlagwörter: |
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| Anmerkung: |
© Société Internationale de Chirurgie 2009 |
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| Übergeordnetes Werk: |
Enthalten in: World Journal of Surgery - Springer-Verlag, 1996, 33(2009), 12 vom: 22. Sept., Seite 2553-2556 |
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| Übergeordnetes Werk: |
volume:33 ; year:2009 ; number:12 ; day:22 ; month:09 ; pages:2553-2556 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00268-009-0203-3 |
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SPR003420922 |
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| 520 | |a Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. | ||
| 650 | 4 | |a Abdominal Wall Defect |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Hernia Defect |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Abdominal Wall Hernia |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Dysport |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Abdominal Wall Reconstruction |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Nuño-Guzmán, Carlos M. |4 aut | |
| 700 | 1 | |a Echeagaray-Herrera, Jorge E. |4 aut | |
| 700 | 1 | |a Robles-Vélez, Everardo |4 aut | |
| 700 | 1 | |a de Jesús González-Jaime, José |4 aut | |
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10.1007/s00268-009-0203-3 doi (DE-627)SPR003420922 (SPR)s00268-009-0203-3-e DE-627 ger DE-627 rakwb eng Ibarra-Hurtado, Tomas R. verfasserin aut Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2009 Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 Nuño-Guzmán, Carlos M. aut Echeagaray-Herrera, Jorge E. aut Robles-Vélez, Everardo aut de Jesús González-Jaime, José aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 33(2009), 12 vom: 22. Sept., Seite 2553-2556 (DE-627)SPR003391159 nnns volume:33 year:2009 number:12 day:22 month:09 pages:2553-2556 https://dx.doi.org/10.1007/s00268-009-0203-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 33 2009 12 22 09 2553-2556 |
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10.1007/s00268-009-0203-3 doi (DE-627)SPR003420922 (SPR)s00268-009-0203-3-e DE-627 ger DE-627 rakwb eng Ibarra-Hurtado, Tomas R. verfasserin aut Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2009 Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 Nuño-Guzmán, Carlos M. aut Echeagaray-Herrera, Jorge E. aut Robles-Vélez, Everardo aut de Jesús González-Jaime, José aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 33(2009), 12 vom: 22. Sept., Seite 2553-2556 (DE-627)SPR003391159 nnns volume:33 year:2009 number:12 day:22 month:09 pages:2553-2556 https://dx.doi.org/10.1007/s00268-009-0203-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 33 2009 12 22 09 2553-2556 |
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10.1007/s00268-009-0203-3 doi (DE-627)SPR003420922 (SPR)s00268-009-0203-3-e DE-627 ger DE-627 rakwb eng Ibarra-Hurtado, Tomas R. verfasserin aut Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2009 Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 Nuño-Guzmán, Carlos M. aut Echeagaray-Herrera, Jorge E. aut Robles-Vélez, Everardo aut de Jesús González-Jaime, José aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 33(2009), 12 vom: 22. Sept., Seite 2553-2556 (DE-627)SPR003391159 nnns volume:33 year:2009 number:12 day:22 month:09 pages:2553-2556 https://dx.doi.org/10.1007/s00268-009-0203-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 33 2009 12 22 09 2553-2556 |
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10.1007/s00268-009-0203-3 doi (DE-627)SPR003420922 (SPR)s00268-009-0203-3-e DE-627 ger DE-627 rakwb eng Ibarra-Hurtado, Tomas R. verfasserin aut Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2009 Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 Nuño-Guzmán, Carlos M. aut Echeagaray-Herrera, Jorge E. aut Robles-Vélez, Everardo aut de Jesús González-Jaime, José aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 33(2009), 12 vom: 22. Sept., Seite 2553-2556 (DE-627)SPR003391159 nnns volume:33 year:2009 number:12 day:22 month:09 pages:2553-2556 https://dx.doi.org/10.1007/s00268-009-0203-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 33 2009 12 22 09 2553-2556 |
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10.1007/s00268-009-0203-3 doi (DE-627)SPR003420922 (SPR)s00268-009-0203-3-e DE-627 ger DE-627 rakwb eng Ibarra-Hurtado, Tomas R. verfasserin aut Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2009 Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 Nuño-Guzmán, Carlos M. aut Echeagaray-Herrera, Jorge E. aut Robles-Vélez, Everardo aut de Jesús González-Jaime, José aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 33(2009), 12 vom: 22. Sept., Seite 2553-2556 (DE-627)SPR003391159 nnns volume:33 year:2009 number:12 day:22 month:09 pages:2553-2556 https://dx.doi.org/10.1007/s00268-009-0203-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 33 2009 12 22 09 2553-2556 |
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In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. 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Ibarra-Hurtado, Tomas R. |
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Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction Abdominal Wall Defect (dpeaa)DE-He213 Hernia Defect (dpeaa)DE-He213 Abdominal Wall Hernia (dpeaa)DE-He213 Dysport (dpeaa)DE-He213 Abdominal Wall Reconstruction (dpeaa)DE-He213 |
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Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction |
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Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction |
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Ibarra-Hurtado, Tomas R. |
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World Journal of Surgery |
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2009 |
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Ibarra-Hurtado, Tomas R. Nuño-Guzmán, Carlos M. Echeagaray-Herrera, Jorge E. Robles-Vélez, Everardo de Jesús González-Jaime, José |
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Ibarra-Hurtado, Tomas R. |
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10.1007/s00268-009-0203-3 |
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use of botulinum toxin type a before abdominal wall hernia reconstruction |
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Use of Botulinum Toxin Type A Before Abdominal Wall Hernia Reconstruction |
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Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. © Société Internationale de Chirurgie 2009 |
| abstractGer |
Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. © Société Internationale de Chirurgie 2009 |
| abstract_unstemmed |
Background Abdominal wall hernia repair after open abdomen management represents a surgical challenge, particularly due to muscle tension and lateral retraction. This study was designed to propose the use of Botulinum Toxin Type A (BTA) before abdominal wall hernia repair. Methods A prospective study of patients with abdominal wall hernia after open abdomen management was undertaken between September 2007 and January 2009. Bilateral BTA application was performed under electromyographic guidance at the abdominal wall. Transverse abdominal wall defect measurement was practiced at weekly intervals: clinically, in the first two patients, and with CT scan in the following 10 patients. Surgical closure was scheduled if no further hernia defect reduction was noted. Patients were followed at monthly hospital visits. Results In the first two patients, a hernia defect reduction of 50 and 47.2%, respectively, was documented by the third week after BTA application, with no further reduction. In the 10 patients under CT scan hernia defect measurement, when comparing the initial mean transverse defect measure and at 4 weeks after BTA application (13.85 ± 1.49 cm vs. 8.6 ± 2.07 cm), an overall mean reduction of 5.25 ± 2.32 cm was observed (p < 0.001; 95% confidence interval, 3.59–6.91). Hernia repair was performed, with no recurrences at a mean follow-up of 9.08 months. Conclusions BTA application before abdominal wall hernia repair seems to be useful. The lateral muscles paralysis achieved and transverse hernia defect reduction allows a minimal tension closure. To our knowledge, this is the first report of BTA application before abdominal wall hernia reconstruction. © Société Internationale de Chirurgie 2009 |
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Nuño-Guzmán, Carlos M. Echeagaray-Herrera, Jorge E. Robles-Vélez, Everardo de Jesús González-Jaime, José |
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