Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy
Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-cl...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hiyoshi, Masahide [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2013 |
|---|
| Schlagwörter: |
Transcatheter Arterial Embolization |
|---|
| Anmerkung: |
© Société Internationale de Chirurgie 2013 |
|---|
| Übergeordnetes Werk: |
Enthalten in: World Journal of Surgery - Springer-Verlag, 1996, 37(2013), 10 vom: 10. Juli, Seite 2436-2442 |
|---|---|
| Übergeordnetes Werk: |
volume:37 ; year:2013 ; number:10 ; day:10 ; month:07 ; pages:2436-2442 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00268-013-2149-8 |
|---|
| Katalog-ID: |
SPR003440362 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | SPR003440362 | ||
| 003 | DE-627 | ||
| 005 | 20230328140108.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201001s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00268-013-2149-8 |2 doi | |
| 035 | |a (DE-627)SPR003440362 | ||
| 035 | |a (SPR)s00268-013-2149-8-e | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Hiyoshi, Masahide |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| 264 | 1 | |c 2013 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a © Société Internationale de Chirurgie 2013 | ||
| 520 | |a Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. | ||
| 650 | 4 | |a Transcatheter Arterial Embolization |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Portal Vein Resection |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Postoperative Pancreatic Fistula |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Soft Pancreas |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pancreatic Texture |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Chijiiwa, Kazuo |4 aut | |
| 700 | 1 | |a Fujii, Yoshiro |4 aut | |
| 700 | 1 | |a Imamura, Naoya |4 aut | |
| 700 | 1 | |a Nagano, Motoaki |4 aut | |
| 700 | 1 | |a Ohuchida, Jiro |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t World Journal of Surgery |d Springer-Verlag, 1996 |g 37(2013), 10 vom: 10. Juli, Seite 2436-2442 |w (DE-627)SPR003391159 |7 nnns |
| 773 | 1 | 8 | |g volume:37 |g year:2013 |g number:10 |g day:10 |g month:07 |g pages:2436-2442 |
| 856 | 4 | 0 | |u https://dx.doi.org/10.1007/s00268-013-2149-8 |z lizenzpflichtig |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_SPRINGER | ||
| 951 | |a AR | ||
| 952 | |d 37 |j 2013 |e 10 |b 10 |c 07 |h 2436-2442 | ||
| author_variant |
m h mh k c kc y f yf n i ni m n mn j o jo |
|---|---|
| matchkey_str |
hiyoshimasahidechijiiwakazuofujiiyoshiro:2013----:sflesfriayaeeuceciertilvladoyeprtrtpeitotprtvpnraif |
| hierarchy_sort_str |
2013 |
| publishDate |
2013 |
| allfields |
10.1007/s00268-013-2149-8 doi (DE-627)SPR003440362 (SPR)s00268-013-2149-8-e DE-627 ger DE-627 rakwb eng Hiyoshi, Masahide verfasserin aut Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 Chijiiwa, Kazuo aut Fujii, Yoshiro aut Imamura, Naoya aut Nagano, Motoaki aut Ohuchida, Jiro aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 37(2013), 10 vom: 10. Juli, Seite 2436-2442 (DE-627)SPR003391159 nnns volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 https://dx.doi.org/10.1007/s00268-013-2149-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 37 2013 10 10 07 2436-2442 |
| spelling |
10.1007/s00268-013-2149-8 doi (DE-627)SPR003440362 (SPR)s00268-013-2149-8-e DE-627 ger DE-627 rakwb eng Hiyoshi, Masahide verfasserin aut Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 Chijiiwa, Kazuo aut Fujii, Yoshiro aut Imamura, Naoya aut Nagano, Motoaki aut Ohuchida, Jiro aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 37(2013), 10 vom: 10. Juli, Seite 2436-2442 (DE-627)SPR003391159 nnns volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 https://dx.doi.org/10.1007/s00268-013-2149-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 37 2013 10 10 07 2436-2442 |
| allfields_unstemmed |
10.1007/s00268-013-2149-8 doi (DE-627)SPR003440362 (SPR)s00268-013-2149-8-e DE-627 ger DE-627 rakwb eng Hiyoshi, Masahide verfasserin aut Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 Chijiiwa, Kazuo aut Fujii, Yoshiro aut Imamura, Naoya aut Nagano, Motoaki aut Ohuchida, Jiro aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 37(2013), 10 vom: 10. Juli, Seite 2436-2442 (DE-627)SPR003391159 nnns volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 https://dx.doi.org/10.1007/s00268-013-2149-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 37 2013 10 10 07 2436-2442 |
| allfieldsGer |
10.1007/s00268-013-2149-8 doi (DE-627)SPR003440362 (SPR)s00268-013-2149-8-e DE-627 ger DE-627 rakwb eng Hiyoshi, Masahide verfasserin aut Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 Chijiiwa, Kazuo aut Fujii, Yoshiro aut Imamura, Naoya aut Nagano, Motoaki aut Ohuchida, Jiro aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 37(2013), 10 vom: 10. Juli, Seite 2436-2442 (DE-627)SPR003391159 nnns volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 https://dx.doi.org/10.1007/s00268-013-2149-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 37 2013 10 10 07 2436-2442 |
| allfieldsSound |
10.1007/s00268-013-2149-8 doi (DE-627)SPR003440362 (SPR)s00268-013-2149-8-e DE-627 ger DE-627 rakwb eng Hiyoshi, Masahide verfasserin aut Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 Chijiiwa, Kazuo aut Fujii, Yoshiro aut Imamura, Naoya aut Nagano, Motoaki aut Ohuchida, Jiro aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 37(2013), 10 vom: 10. Juli, Seite 2436-2442 (DE-627)SPR003391159 nnns volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 https://dx.doi.org/10.1007/s00268-013-2149-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 37 2013 10 10 07 2436-2442 |
| language |
English |
| source |
Enthalten in World Journal of Surgery 37(2013), 10 vom: 10. Juli, Seite 2436-2442 volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 |
| sourceStr |
Enthalten in World Journal of Surgery 37(2013), 10 vom: 10. Juli, Seite 2436-2442 volume:37 year:2013 number:10 day:10 month:07 pages:2436-2442 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
Transcatheter Arterial Embolization Portal Vein Resection Postoperative Pancreatic Fistula Soft Pancreas Pancreatic Texture |
| isfreeaccess_bool |
false |
| container_title |
World Journal of Surgery |
| authorswithroles_txt_mv |
Hiyoshi, Masahide @@aut@@ Chijiiwa, Kazuo @@aut@@ Fujii, Yoshiro @@aut@@ Imamura, Naoya @@aut@@ Nagano, Motoaki @@aut@@ Ohuchida, Jiro @@aut@@ |
| publishDateDaySort_date |
2013-07-10T00:00:00Z |
| hierarchy_top_id |
SPR003391159 |
| id |
SPR003440362 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003440362</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230328140108.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2013 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-013-2149-8</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003440362</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-013-2149-8-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hiyoshi, Masahide</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2013</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transcatheter Arterial Embolization</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Portal Vein Resection</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Postoperative Pancreatic Fistula</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Soft Pancreas</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pancreatic Texture</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chijiiwa, Kazuo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fujii, Yoshiro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Imamura, Naoya</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagano, Motoaki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohuchida, Jiro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">37(2013), 10 vom: 10. Juli, Seite 2436-2442</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2013</subfield><subfield code="g">number:10</subfield><subfield code="g">day:10</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:2436-2442</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-013-2149-8</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2013</subfield><subfield code="e">10</subfield><subfield code="b">10</subfield><subfield code="c">07</subfield><subfield code="h">2436-2442</subfield></datafield></record></collection>
|
| author |
Hiyoshi, Masahide |
| spellingShingle |
Hiyoshi, Masahide misc Transcatheter Arterial Embolization misc Portal Vein Resection misc Postoperative Pancreatic Fistula misc Soft Pancreas misc Pancreatic Texture Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| authorStr |
Hiyoshi, Masahide |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)SPR003391159 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut |
| collection |
springer |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Transcatheter Arterial Embolization (dpeaa)DE-He213 Portal Vein Resection (dpeaa)DE-He213 Postoperative Pancreatic Fistula (dpeaa)DE-He213 Soft Pancreas (dpeaa)DE-He213 Pancreatic Texture (dpeaa)DE-He213 |
| topic |
misc Transcatheter Arterial Embolization misc Portal Vein Resection misc Postoperative Pancreatic Fistula misc Soft Pancreas misc Pancreatic Texture |
| topic_unstemmed |
misc Transcatheter Arterial Embolization misc Portal Vein Resection misc Postoperative Pancreatic Fistula misc Soft Pancreas misc Pancreatic Texture |
| topic_browse |
misc Transcatheter Arterial Embolization misc Portal Vein Resection misc Postoperative Pancreatic Fistula misc Soft Pancreas misc Pancreatic Texture |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
World Journal of Surgery |
| hierarchy_parent_id |
SPR003391159 |
| hierarchy_top_title |
World Journal of Surgery |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)SPR003391159 |
| title |
Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| ctrlnum |
(DE-627)SPR003440362 (SPR)s00268-013-2149-8-e |
| title_full |
Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| author_sort |
Hiyoshi, Masahide |
| journal |
World Journal of Surgery |
| journalStr |
World Journal of Surgery |
| lang_code |
eng |
| isOA_bool |
false |
| recordtype |
marc |
| publishDateSort |
2013 |
| contenttype_str_mv |
txt |
| container_start_page |
2436 |
| author_browse |
Hiyoshi, Masahide Chijiiwa, Kazuo Fujii, Yoshiro Imamura, Naoya Nagano, Motoaki Ohuchida, Jiro |
| container_volume |
37 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Hiyoshi, Masahide |
| doi_str_mv |
10.1007/s00268-013-2149-8 |
| title_sort |
usefulness of drain amylase, serum c-reactive protein levels and body temperature to predict postoperative pancreatic fistula after pancreaticoduodenectomy |
| title_auth |
Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| abstract |
Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. © Société Internationale de Chirurgie 2013 |
| abstractGer |
Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. © Société Internationale de Chirurgie 2013 |
| abstract_unstemmed |
Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated. © Société Internationale de Chirurgie 2013 |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER |
| container_issue |
10 |
| title_short |
Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy |
| url |
https://dx.doi.org/10.1007/s00268-013-2149-8 |
| remote_bool |
true |
| author2 |
Chijiiwa, Kazuo Fujii, Yoshiro Imamura, Naoya Nagano, Motoaki Ohuchida, Jiro |
| author2Str |
Chijiiwa, Kazuo Fujii, Yoshiro Imamura, Naoya Nagano, Motoaki Ohuchida, Jiro |
| ppnlink |
SPR003391159 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1007/s00268-013-2149-8 |
| up_date |
2024-07-03T19:30:09.363Z |
| _version_ |
1803587429980962816 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR003440362</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230328140108.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2013 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00268-013-2149-8</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR003440362</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00268-013-2149-8-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hiyoshi, Masahide</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Usefulness of Drain Amylase, Serum C-Reactive Protein Levels and Body Temperature to Predict Postoperative Pancreatic Fistula After Pancreaticoduodenectomy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2013</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Société Internationale de Chirurgie 2013</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a worrisome and life-threatening complication. Recently, early drain removal has been recommended as a means of preventing POPF. The present study sought to determine how to distinguish clinical POPF from non-clinical POPF in the early postoperative period after PD to aid in early drain removal. Methods From March 2002 through December 2010, 176 patients underwent PD and were enrolled in this study to examine factors predictive of clinical POPF after PD. POPF was defined and classified according to the International Study Group of Pancreatic Surgery guideline, and grade B/C POPF was defined as clinical POPF. Results Grade A POPF occurred in 39 (22.2 %) patients, grade B in 19 (10.8 %) patients, and grade C in 11 (6.3 %) patients. Clinical POPF (grade B/C) occurred in 17.1 % of patients. Multivariate analysis revealed male gender and body mass index (BMI) ≥22.5 kg/$ m^{2} $ to be the independent preoperative risk factors predictive of POPF. Receiver operating characteristic curves showed that the combination of drain amylase ≥750 IU/L, C-reactive protein (CRP) ≥20 mg/dL, and body temperature ≥37.5 °C on postoperative day 3 could effectively distinguish clinical POPF from non-clinical POPF. Sensitivity, specificity, and accuracy were 84.6, 98.2, and 95.7 %, respectively. Conclusions Male gender and BMI ≥22.5 were the independent preoperative predictive risk factors for POPF. We assume that when amylase is <750 IU/L, serum CRP is <20 mg/dL, and body temperature is <37.5 °C the drain can safely be removed, even if POPF is indicated.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transcatheter Arterial Embolization</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Portal Vein Resection</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Postoperative Pancreatic Fistula</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Soft Pancreas</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pancreatic Texture</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chijiiwa, Kazuo</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fujii, Yoshiro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Imamura, Naoya</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nagano, Motoaki</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ohuchida, Jiro</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">World Journal of Surgery</subfield><subfield code="d">Springer-Verlag, 1996</subfield><subfield code="g">37(2013), 10 vom: 10. Juli, Seite 2436-2442</subfield><subfield code="w">(DE-627)SPR003391159</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:37</subfield><subfield code="g">year:2013</subfield><subfield code="g">number:10</subfield><subfield code="g">day:10</subfield><subfield code="g">month:07</subfield><subfield code="g">pages:2436-2442</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://dx.doi.org/10.1007/s00268-013-2149-8</subfield><subfield code="z">lizenzpflichtig</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_SPRINGER</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">37</subfield><subfield code="j">2013</subfield><subfield code="e">10</subfield><subfield code="b">10</subfield><subfield code="c">07</subfield><subfield code="h">2436-2442</subfield></datafield></record></collection>
|
| score |
7.401101 |