Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials
Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due t...
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Gespeichert in:
| Autor*in: |
Greco, Massimiliano [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Anmerkung: |
© Société Internationale de Chirurgie 2013 |
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| Übergeordnetes Werk: |
Enthalten in: World Journal of Surgery - Springer-Verlag, 1996, 38(2013), 6 vom: 25. Dez., Seite 1531-1541 |
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| Übergeordnetes Werk: |
volume:38 ; year:2013 ; number:6 ; day:25 ; month:12 ; pages:1531-1541 |
| Links: |
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| DOI / URN: |
10.1007/s00268-013-2416-8 |
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SPR003447588 |
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| 520 | |a Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. | ||
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10.1007/s00268-013-2416-8 doi (DE-627)SPR003447588 (SPR)s00268-013-2416-8-e DE-627 ger DE-627 rakwb eng Greco, Massimiliano verfasserin aut Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. Readmission Rate (dpeaa)DE-He213 Relative Ratio (dpeaa)DE-He213 Enhance Recovery After Surgery (dpeaa)DE-He213 Weighted Mean Difference (dpeaa)DE-He213 Elective Colorectal Surgery (dpeaa)DE-He213 Capretti, Giovanni aut Beretta, Luigi aut Gemma, Marco aut Pecorelli, Nicolò aut Braga, Marco aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 38(2013), 6 vom: 25. Dez., Seite 1531-1541 (DE-627)SPR003391159 nnns volume:38 year:2013 number:6 day:25 month:12 pages:1531-1541 https://dx.doi.org/10.1007/s00268-013-2416-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 38 2013 6 25 12 1531-1541 |
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10.1007/s00268-013-2416-8 doi (DE-627)SPR003447588 (SPR)s00268-013-2416-8-e DE-627 ger DE-627 rakwb eng Greco, Massimiliano verfasserin aut Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. Readmission Rate (dpeaa)DE-He213 Relative Ratio (dpeaa)DE-He213 Enhance Recovery After Surgery (dpeaa)DE-He213 Weighted Mean Difference (dpeaa)DE-He213 Elective Colorectal Surgery (dpeaa)DE-He213 Capretti, Giovanni aut Beretta, Luigi aut Gemma, Marco aut Pecorelli, Nicolò aut Braga, Marco aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 38(2013), 6 vom: 25. Dez., Seite 1531-1541 (DE-627)SPR003391159 nnns volume:38 year:2013 number:6 day:25 month:12 pages:1531-1541 https://dx.doi.org/10.1007/s00268-013-2416-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 38 2013 6 25 12 1531-1541 |
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10.1007/s00268-013-2416-8 doi (DE-627)SPR003447588 (SPR)s00268-013-2416-8-e DE-627 ger DE-627 rakwb eng Greco, Massimiliano verfasserin aut Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. Readmission Rate (dpeaa)DE-He213 Relative Ratio (dpeaa)DE-He213 Enhance Recovery After Surgery (dpeaa)DE-He213 Weighted Mean Difference (dpeaa)DE-He213 Elective Colorectal Surgery (dpeaa)DE-He213 Capretti, Giovanni aut Beretta, Luigi aut Gemma, Marco aut Pecorelli, Nicolò aut Braga, Marco aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 38(2013), 6 vom: 25. Dez., Seite 1531-1541 (DE-627)SPR003391159 nnns volume:38 year:2013 number:6 day:25 month:12 pages:1531-1541 https://dx.doi.org/10.1007/s00268-013-2416-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 38 2013 6 25 12 1531-1541 |
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10.1007/s00268-013-2416-8 doi (DE-627)SPR003447588 (SPR)s00268-013-2416-8-e DE-627 ger DE-627 rakwb eng Greco, Massimiliano verfasserin aut Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. Readmission Rate (dpeaa)DE-He213 Relative Ratio (dpeaa)DE-He213 Enhance Recovery After Surgery (dpeaa)DE-He213 Weighted Mean Difference (dpeaa)DE-He213 Elective Colorectal Surgery (dpeaa)DE-He213 Capretti, Giovanni aut Beretta, Luigi aut Gemma, Marco aut Pecorelli, Nicolò aut Braga, Marco aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 38(2013), 6 vom: 25. Dez., Seite 1531-1541 (DE-627)SPR003391159 nnns volume:38 year:2013 number:6 day:25 month:12 pages:1531-1541 https://dx.doi.org/10.1007/s00268-013-2416-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 38 2013 6 25 12 1531-1541 |
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10.1007/s00268-013-2416-8 doi (DE-627)SPR003447588 (SPR)s00268-013-2416-8-e DE-627 ger DE-627 rakwb eng Greco, Massimiliano verfasserin aut Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Société Internationale de Chirurgie 2013 Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. Readmission Rate (dpeaa)DE-He213 Relative Ratio (dpeaa)DE-He213 Enhance Recovery After Surgery (dpeaa)DE-He213 Weighted Mean Difference (dpeaa)DE-He213 Elective Colorectal Surgery (dpeaa)DE-He213 Capretti, Giovanni aut Beretta, Luigi aut Gemma, Marco aut Pecorelli, Nicolò aut Braga, Marco aut Enthalten in World Journal of Surgery Springer-Verlag, 1996 38(2013), 6 vom: 25. Dez., Seite 1531-1541 (DE-627)SPR003391159 nnns volume:38 year:2013 number:6 day:25 month:12 pages:1531-1541 https://dx.doi.org/10.1007/s00268-013-2416-8 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER AR 38 2013 6 25 12 1531-1541 |
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However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. 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Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials |
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Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials |
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Greco, Massimiliano |
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Greco, Massimiliano Capretti, Giovanni Beretta, Luigi Gemma, Marco Pecorelli, Nicolò Braga, Marco |
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10.1007/s00268-013-2416-8 |
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enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials |
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Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials |
| abstract |
Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. © Société Internationale de Chirurgie 2013 |
| abstractGer |
Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. © Société Internationale de Chirurgie 2013 |
| abstract_unstemmed |
Background Meta-analyses in the literature show that enhanced recovery after surgery (ERAS) is associated with lower morbidity rate and shorter hospital stay after elective colorectal surgery. However, a recent Cochrane review did not indicate the ERAS pathway as being the new standard of care due to the limited number of published trials, together with their poor quality. We conducted a meta-analysis of randomized controlled trials (RCTs) to assess the impact of the ERAS pathway on overall morbidity, single postoperative complications, length of hospital stay, and readmission rate following colorectal surgery. Methods We searched BioMedCentral, PubMed, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) for RCTs comparing the ERAS pathway to conventional perioperative care. No language restrictions were considered. A quality score was calculated for each trial included. Results A total of 2,376 patients in 16 RCTs were included in the analysis. The ERAS pathway was associated with a reduction of overall morbidity [relative ratio (RR) = 0.60, (95 % CI 0.46–0.76)], particularly with respect to nonsurgical complications [RR = 0.40, (95 % CI 0.27–0.61)]. The reduction of surgical complications was not significant [RR = 0.76, (95 % CI 0.54–1.08)]. The ERAS pathway shortened hospital stay (WMD = −2.28 days [95 % CI –3.09 to –1.47]), without increasing readmission rate. Conclusions The ERAS pathway reduced overall morbidity rates and shortened the length of hospital stay, without increasing readmission rates. A significant reduction in nonsurgical complications was evident, while no significant reduction was found for surgical complications. © Société Internationale de Chirurgie 2013 |
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Enhanced Recovery Program in Colorectal Surgery: A Meta-analysis of Randomized Controlled Trials |
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Capretti, Giovanni Beretta, Luigi Gemma, Marco Pecorelli, Nicolò Braga, Marco |
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