Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience

Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were incl...
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Autor*in:	Sivaraman, Arjun [verfasserIn] Sanchez-Salas, Rafael Barret, Eric Macek, Petr Validire, Pierre Galiano, Marc Rozet, Francois Cathelineau, Xavier

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Prostate histoscanning Prostate biopsy Target biopsy Prostate cancer TRUS biopsy

Anmerkung:	© Springer-Verlag Berlin Heidelberg 2014

Übergeordnetes Werk:	Enthalten in: World journal of urology - Berlin : Springer, 1983, 33(2014), 10 vom: 12. Dez., Seite 1475-1479
Übergeordnetes Werk:	volume:33 ; year:2014 ; number:10 ; day:12 ; month:12 ; pages:1475-1479

Links:	Volltext

DOI / URN:	10.1007/s00345-014-1434-y

Katalog-ID:	SPR004312295

Internformat


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245	1	0	\|a Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
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520			\|a Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies.
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700	1		\|a Sanchez-Salas, Rafael \|4 aut
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700	1		\|a Macek, Petr \|4 aut
700	1		\|a Validire, Pierre \|4 aut
700	1		\|a Galiano, Marc \|4 aut
700	1		\|a Rozet, Francois \|4 aut
700	1		\|a Cathelineau, Xavier \|4 aut
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allfields	10.1007/s00345-014-1434-y doi (DE-627)SPR004312295 (SPR)s00345-014-1434-y-e DE-627 ger DE-627 rakwb eng Sivaraman, Arjun verfasserin aut Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2014 Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213 Sanchez-Salas, Rafael aut Barret, Eric aut Macek, Petr aut Validire, Pierre aut Galiano, Marc aut Rozet, Francois aut Cathelineau, Xavier aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2014), 10 vom: 12. Dez., Seite 1475-1479 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479 https://dx.doi.org/10.1007/s00345-014-1434-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2014 10 12 12 1475-1479
spelling	10.1007/s00345-014-1434-y doi (DE-627)SPR004312295 (SPR)s00345-014-1434-y-e DE-627 ger DE-627 rakwb eng Sivaraman, Arjun verfasserin aut Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2014 Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213 Sanchez-Salas, Rafael aut Barret, Eric aut Macek, Petr aut Validire, Pierre aut Galiano, Marc aut Rozet, Francois aut Cathelineau, Xavier aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2014), 10 vom: 12. Dez., Seite 1475-1479 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479 https://dx.doi.org/10.1007/s00345-014-1434-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2014 10 12 12 1475-1479
allfields_unstemmed	10.1007/s00345-014-1434-y doi (DE-627)SPR004312295 (SPR)s00345-014-1434-y-e DE-627 ger DE-627 rakwb eng Sivaraman, Arjun verfasserin aut Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2014 Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213 Sanchez-Salas, Rafael aut Barret, Eric aut Macek, Petr aut Validire, Pierre aut Galiano, Marc aut Rozet, Francois aut Cathelineau, Xavier aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2014), 10 vom: 12. Dez., Seite 1475-1479 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479 https://dx.doi.org/10.1007/s00345-014-1434-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2014 10 12 12 1475-1479
allfieldsGer	10.1007/s00345-014-1434-y doi (DE-627)SPR004312295 (SPR)s00345-014-1434-y-e DE-627 ger DE-627 rakwb eng Sivaraman, Arjun verfasserin aut Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2014 Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213 Sanchez-Salas, Rafael aut Barret, Eric aut Macek, Petr aut Validire, Pierre aut Galiano, Marc aut Rozet, Francois aut Cathelineau, Xavier aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2014), 10 vom: 12. Dez., Seite 1475-1479 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479 https://dx.doi.org/10.1007/s00345-014-1434-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2014 10 12 12 1475-1479
allfieldsSound	10.1007/s00345-014-1434-y doi (DE-627)SPR004312295 (SPR)s00345-014-1434-y-e DE-627 ger DE-627 rakwb eng Sivaraman, Arjun verfasserin aut Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2014 Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213 Sanchez-Salas, Rafael aut Barret, Eric aut Macek, Petr aut Validire, Pierre aut Galiano, Marc aut Rozet, Francois aut Cathelineau, Xavier aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2014), 10 vom: 12. Dez., Seite 1475-1479 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479 https://dx.doi.org/10.1007/s00345-014-1434-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2014 10 12 12 1475-1479
language	English
source	Enthalten in World journal of urology 33(2014), 10 vom: 12. Dez., Seite 1475-1479 volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479
sourceStr	Enthalten in World journal of urology 33(2014), 10 vom: 12. Dez., Seite 1475-1479 volume:33 year:2014 number:10 day:12 month:12 pages:1475-1479
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Prostate histoscanning Prostate biopsy Target biopsy Prostate cancer TRUS biopsy
isfreeaccess_bool	false
container_title	World journal of urology
authorswithroles_txt_mv	Sivaraman, Arjun @@aut@@ Sanchez-Salas, Rafael @@aut@@ Barret, Eric @@aut@@ Macek, Petr @@aut@@ Validire, Pierre @@aut@@ Galiano, Marc @@aut@@ Rozet, Francois @@aut@@ Cathelineau, Xavier @@aut@@
publishDateDaySort_date	2014-12-12T00:00:00Z
hierarchy_top_id	254910874
id	SPR004312295
language_de	englisch
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Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. 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author	Sivaraman, Arjun
spellingShingle	Sivaraman, Arjun misc Prostate histoscanning misc Prostate biopsy misc Target biopsy misc Prostate cancer misc TRUS biopsy Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
authorStr	Sivaraman, Arjun
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topic_title	Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience Prostate histoscanning (dpeaa)DE-He213 Prostate biopsy (dpeaa)DE-He213 Target biopsy (dpeaa)DE-He213 Prostate cancer (dpeaa)DE-He213 TRUS biopsy (dpeaa)DE-He213
topic	misc Prostate histoscanning misc Prostate biopsy misc Target biopsy misc Prostate cancer misc TRUS biopsy
topic_unstemmed	misc Prostate histoscanning misc Prostate biopsy misc Target biopsy misc Prostate cancer misc TRUS biopsy
topic_browse	misc Prostate histoscanning misc Prostate biopsy misc Target biopsy misc Prostate cancer misc TRUS biopsy
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title	Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
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title_full	Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
author_sort	Sivaraman, Arjun
journal	World journal of urology
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author_browse	Sivaraman, Arjun Sanchez-Salas, Rafael Barret, Eric Macek, Petr Validire, Pierre Galiano, Marc Rozet, Francois Cathelineau, Xavier
container_volume	33
format_se	Elektronische Aufsätze
author-letter	Sivaraman, Arjun
doi_str_mv	10.1007/s00345-014-1434-y
title_sort	prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
title_auth	Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
abstract	Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. © Springer-Verlag Berlin Heidelberg 2014
abstractGer	Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. © Springer-Verlag Berlin Heidelberg 2014
abstract_unstemmed	Objective To evaluate the feasibility of prostate histoscanning true targeting (PHS-TT) guided transrectal ultrasound (TRUS) biopsy. Methods This is a prospective, single center, pilot study performed during February 2013–September 2013. All consecutive patients planned for prostate biopsy were included in the study, and all the procedure was performed by a single surgeon aided by the specialized true targeting software. Initially, the patients underwent PHS to map the abnormal areas within the prostate that were ≥0.2 $ cm^{3} $. TRUS guided biopsies were performed targeting the abnormal areas with a specialized software. Additionally, routine bisextant biopsies were also taken. The final histopathology of the target cores was compared with the bisextant cores. Results A total of 43 patients underwent combined ‘targeted PHS guided’ and ‘standard 12 core systematic’ biopsies. The mean volume of abnormal area detected by PHS is 4.3 $ cm^{3} $. The overall cancer detection rate was 46.5 % (20/43) with systemic cores and target cores detecting cancer in 44 % (19/43) and 26 % (11/43), respectively. The mean % cancer/core length of the PHS-TT cores were significantly higher than the systematic cores (55.4 vs. 37.5 %. p < 0.05). In biopsy naïve patients, the cancer detection rate (43.7 % vs. 14.8 %. p = 0.06) and the cancer positivity of the cores (30.1 vs. 6.8 %. p < 0.01) of target cores were higher than those patients with prior biopsies. Conclusion PHS-TT is feasible and can be an effective tool for real-time guidance of prostate biopsies. © Springer-Verlag Berlin Heidelberg 2014
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container_issue	10
title_short	Prostate histoscanning true targeting guided prostate biopsy: initial clinical experience
url	https://dx.doi.org/10.1007/s00345-014-1434-y
remote_bool	true
author2	Sanchez-Salas, Rafael Barret, Eric Macek, Petr Validire, Pierre Galiano, Marc Rozet, Francois Cathelineau, Xavier
author2Str	Sanchez-Salas, Rafael Barret, Eric Macek, Petr Validire, Pierre Galiano, Marc Rozet, Francois Cathelineau, Xavier
ppnlink	254910874
mediatype_str_mv	c
isOA_txt	false
hochschulschrift_bool	false
doi_str	10.1007/s00345-014-1434-y
up_date	2024-07-04T00:37:18.463Z
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