The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy
Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Peyronnet, Benoit [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Schlagwörter: |
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| Anmerkung: |
© Springer-Verlag Berlin Heidelberg 2015 |
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| Übergeordnetes Werk: |
Enthalten in: World journal of urology - Berlin : Springer, 1983, 33(2015), 11 vom: 29. März, Seite 1815-1820 |
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| Übergeordnetes Werk: |
volume:33 ; year:2015 ; number:11 ; day:29 ; month:03 ; pages:1815-1820 |
| Links: |
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| DOI / URN: |
10.1007/s00345-015-1537-0 |
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| Katalog-ID: |
SPR004312864 |
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| 041 | |a eng | ||
| 100 | 1 | |a Peyronnet, Benoit |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
| 264 | 1 | |c 2015 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
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| 500 | |a © Springer-Verlag Berlin Heidelberg 2015 | ||
| 520 | |a Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. | ||
| 650 | 4 | |a Robotic |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Partial nephrectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Hemostatic agent |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Complications |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Outcomes |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Fibrin sealant |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Oger, Emmanuel |4 aut | |
| 700 | 1 | |a Khene, Zineddine |4 aut | |
| 700 | 1 | |a Verhoest, Gregory |4 aut | |
| 700 | 1 | |a Mathieu, Romain |4 aut | |
| 700 | 1 | |a Roumiguié, Mathieu |4 aut | |
| 700 | 1 | |a Beauval, Jean-Baptiste |4 aut | |
| 700 | 1 | |a Pradere, Benjamin |4 aut | |
| 700 | 1 | |a Masson-Lecomte, Alexandra |4 aut | |
| 700 | 1 | |a Vaessen, Christophe |4 aut | |
| 700 | 1 | |a Baumert, Hervé |4 aut | |
| 700 | 1 | |a Bernhard, Jean-Christophe |4 aut | |
| 700 | 1 | |a Doumerc, Nicolas |4 aut | |
| 700 | 1 | |a Droupy, Stéphane |4 aut | |
| 700 | 1 | |a Bruyere, Franck |4 aut | |
| 700 | 1 | |a De La Taille, Alexandre |4 aut | |
| 700 | 1 | |a Roupret, Morgan |4 aut | |
| 700 | 1 | |a Bensalah, Karim |4 aut | |
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10.1007/s00345-015-1537-0 doi (DE-627)SPR004312864 (SPR)s00345-015-1537-0-e DE-627 ger DE-627 rakwb eng Peyronnet, Benoit verfasserin aut The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 Oger, Emmanuel aut Khene, Zineddine aut Verhoest, Gregory aut Mathieu, Romain aut Roumiguié, Mathieu aut Beauval, Jean-Baptiste aut Pradere, Benjamin aut Masson-Lecomte, Alexandra aut Vaessen, Christophe aut Baumert, Hervé aut Bernhard, Jean-Christophe aut Doumerc, Nicolas aut Droupy, Stéphane aut Bruyere, Franck aut De La Taille, Alexandre aut Roupret, Morgan aut Bensalah, Karim aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2015), 11 vom: 29. März, Seite 1815-1820 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 https://dx.doi.org/10.1007/s00345-015-1537-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2015 11 29 03 1815-1820 |
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10.1007/s00345-015-1537-0 doi (DE-627)SPR004312864 (SPR)s00345-015-1537-0-e DE-627 ger DE-627 rakwb eng Peyronnet, Benoit verfasserin aut The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 Oger, Emmanuel aut Khene, Zineddine aut Verhoest, Gregory aut Mathieu, Romain aut Roumiguié, Mathieu aut Beauval, Jean-Baptiste aut Pradere, Benjamin aut Masson-Lecomte, Alexandra aut Vaessen, Christophe aut Baumert, Hervé aut Bernhard, Jean-Christophe aut Doumerc, Nicolas aut Droupy, Stéphane aut Bruyere, Franck aut De La Taille, Alexandre aut Roupret, Morgan aut Bensalah, Karim aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2015), 11 vom: 29. März, Seite 1815-1820 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 https://dx.doi.org/10.1007/s00345-015-1537-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2015 11 29 03 1815-1820 |
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10.1007/s00345-015-1537-0 doi (DE-627)SPR004312864 (SPR)s00345-015-1537-0-e DE-627 ger DE-627 rakwb eng Peyronnet, Benoit verfasserin aut The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 Oger, Emmanuel aut Khene, Zineddine aut Verhoest, Gregory aut Mathieu, Romain aut Roumiguié, Mathieu aut Beauval, Jean-Baptiste aut Pradere, Benjamin aut Masson-Lecomte, Alexandra aut Vaessen, Christophe aut Baumert, Hervé aut Bernhard, Jean-Christophe aut Doumerc, Nicolas aut Droupy, Stéphane aut Bruyere, Franck aut De La Taille, Alexandre aut Roupret, Morgan aut Bensalah, Karim aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2015), 11 vom: 29. März, Seite 1815-1820 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 https://dx.doi.org/10.1007/s00345-015-1537-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2015 11 29 03 1815-1820 |
| allfieldsGer |
10.1007/s00345-015-1537-0 doi (DE-627)SPR004312864 (SPR)s00345-015-1537-0-e DE-627 ger DE-627 rakwb eng Peyronnet, Benoit verfasserin aut The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 Oger, Emmanuel aut Khene, Zineddine aut Verhoest, Gregory aut Mathieu, Romain aut Roumiguié, Mathieu aut Beauval, Jean-Baptiste aut Pradere, Benjamin aut Masson-Lecomte, Alexandra aut Vaessen, Christophe aut Baumert, Hervé aut Bernhard, Jean-Christophe aut Doumerc, Nicolas aut Droupy, Stéphane aut Bruyere, Franck aut De La Taille, Alexandre aut Roupret, Morgan aut Bensalah, Karim aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2015), 11 vom: 29. März, Seite 1815-1820 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 https://dx.doi.org/10.1007/s00345-015-1537-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2015 11 29 03 1815-1820 |
| allfieldsSound |
10.1007/s00345-015-1537-0 doi (DE-627)SPR004312864 (SPR)s00345-015-1537-0-e DE-627 ger DE-627 rakwb eng Peyronnet, Benoit verfasserin aut The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 Oger, Emmanuel aut Khene, Zineddine aut Verhoest, Gregory aut Mathieu, Romain aut Roumiguié, Mathieu aut Beauval, Jean-Baptiste aut Pradere, Benjamin aut Masson-Lecomte, Alexandra aut Vaessen, Christophe aut Baumert, Hervé aut Bernhard, Jean-Christophe aut Doumerc, Nicolas aut Droupy, Stéphane aut Bruyere, Franck aut De La Taille, Alexandre aut Roupret, Morgan aut Bensalah, Karim aut Enthalten in World journal of urology Berlin : Springer, 1983 33(2015), 11 vom: 29. März, Seite 1815-1820 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 https://dx.doi.org/10.1007/s00345-015-1537-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 33 2015 11 29 03 1815-1820 |
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Enthalten in World journal of urology 33(2015), 11 vom: 29. März, Seite 1815-1820 volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 |
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Enthalten in World journal of urology 33(2015), 11 vom: 29. März, Seite 1815-1820 volume:33 year:2015 number:11 day:29 month:03 pages:1815-1820 |
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Robotic Partial nephrectomy Hemostatic agent Complications Outcomes Fibrin sealant |
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Peyronnet, Benoit @@aut@@ Oger, Emmanuel @@aut@@ Khene, Zineddine @@aut@@ Verhoest, Gregory @@aut@@ Mathieu, Romain @@aut@@ Roumiguié, Mathieu @@aut@@ Beauval, Jean-Baptiste @@aut@@ Pradere, Benjamin @@aut@@ Masson-Lecomte, Alexandra @@aut@@ Vaessen, Christophe @@aut@@ Baumert, Hervé @@aut@@ Bernhard, Jean-Christophe @@aut@@ Doumerc, Nicolas @@aut@@ Droupy, Stéphane @@aut@@ Bruyere, Franck @@aut@@ De La Taille, Alexandre @@aut@@ Roupret, Morgan @@aut@@ Bensalah, Karim @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR004312864</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519123905.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2015 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00345-015-1537-0</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR004312864</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00345-015-1537-0-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Peyronnet, Benoit</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">© Springer-Verlag Berlin Heidelberg 2015</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. 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|
| author |
Peyronnet, Benoit |
| spellingShingle |
Peyronnet, Benoit misc Robotic misc Partial nephrectomy misc Hemostatic agent misc Complications misc Outcomes misc Fibrin sealant The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
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Peyronnet, Benoit |
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electronic Article |
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Not Illustrated |
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1433-8726 |
| topic_title |
The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy Robotic (dpeaa)DE-He213 Partial nephrectomy (dpeaa)DE-He213 Hemostatic agent (dpeaa)DE-He213 Complications (dpeaa)DE-He213 Outcomes (dpeaa)DE-He213 Fibrin sealant (dpeaa)DE-He213 |
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misc Robotic misc Partial nephrectomy misc Hemostatic agent misc Complications misc Outcomes misc Fibrin sealant |
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misc Robotic misc Partial nephrectomy misc Hemostatic agent misc Complications misc Outcomes misc Fibrin sealant |
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misc Robotic misc Partial nephrectomy misc Hemostatic agent misc Complications misc Outcomes misc Fibrin sealant |
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Elektronische Aufsätze Aufsätze Elektronische Ressource |
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The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
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The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
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Peyronnet, Benoit |
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Peyronnet, Benoit Oger, Emmanuel Khene, Zineddine Verhoest, Gregory Mathieu, Romain Roumiguié, Mathieu Beauval, Jean-Baptiste Pradere, Benjamin Masson-Lecomte, Alexandra Vaessen, Christophe Baumert, Hervé Bernhard, Jean-Christophe Doumerc, Nicolas Droupy, Stéphane Bruyere, Franck De La Taille, Alexandre Roupret, Morgan Bensalah, Karim |
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Elektronische Aufsätze |
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use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
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The use of hemostatic agents does not prevent hemorrhagic complications of robotic partial nephrectomy |
| abstract |
Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. © Springer-Verlag Berlin Heidelberg 2015 |
| abstractGer |
Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. © Springer-Verlag Berlin Heidelberg 2015 |
| abstract_unstemmed |
Purpose To assess the impact of HA on robotic PN (RPN) outcomes. Methods We retrospectively analyzed data from patients who underwent RPN in eight centers between 2009 and 2013. Hemorrhagic complications were defined as the occurrence of a pseudoaneurysm, arteriovenous fistula or hematoma requiring transfusion. Patients were first divided into two groups: group A (use of at least one HA) and group B (no HA used), and then into five groups to assess the impact of each HA: group 1 (no HA), group 2 ($ Floseal^{®} $ only), group 3 ($ Surgicel^{®} $ only), group 4 ($ Tachosil^{®} $ only) and group 5 ($ Surgicel^{®} $ + $ Floseal^{®} $). The impact of HA was evaluated by univariate and multivariate analysis. Results Out of 515 RPN, 315 (61 %) were done using at least one HA (group A) and 200 (39 %) were done without any HA (group B). Patients in both groups had similar hemorrhagic complication rates (13 % vs. 15 %, p = 0.42) and postoperative complication rates (19 % vs. 23 %, p = 0.32). In multivariate analysis, the absence of HA was not a risk factor for hemorrhagic complications (OR 0.77, p = 0.54). When each type of HA was considered individually, none was associated with the occurrence of hemorrhagic complication either in univariate or in multivariate analysis. Conclusion In this multicenter study, the use of HA was not associated with a lower risk of hemorrhagic or global complications. © Springer-Verlag Berlin Heidelberg 2015 |
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Oger, Emmanuel Khene, Zineddine Verhoest, Gregory Mathieu, Romain Roumiguié, Mathieu Beauval, Jean-Baptiste Pradere, Benjamin Masson-Lecomte, Alexandra Vaessen, Christophe Baumert, Hervé Bernhard, Jean-Christophe Doumerc, Nicolas Droupy, Stéphane Bruyere, Franck De La Taille, Alexandre Roupret, Morgan Bensalah, Karim |
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| score |
7.402669 |