Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study

Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It includ...
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Autor*in:	Renard-Penna, Raphaële [verfasserIn] Roupret, Morgan Compérat, Eva Rozet, François Granger, Benjamin Barkatz, Johann Bitker, Marc Olivier Lucidarme, Olivier Cussenot, Olivier Mozer, Pierre

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Prostate neoplasms Biopsy Prostate-specific antigen MRI Gleason score

Anmerkung:	© Springer-Verlag Berlin Heidelberg 2015

Übergeordnetes Werk:	Enthalten in: World journal of urology - Berlin : Springer, 1983, 34(2015), 5 vom: 24. Sept., Seite 673-678
Übergeordnetes Werk:	volume:34 ; year:2015 ; number:5 ; day:24 ; month:09 ; pages:673-678

Links:	Volltext

DOI / URN:	10.1007/s00345-015-1685-2

Katalog-ID:	SPR004316568

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100	1		\|a Renard-Penna, Raphaële \|e verfasserin \|4 aut
245	1	0	\|a Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
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520			\|a Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies.
650		4	\|a Prostate neoplasms \|7 (dpeaa)DE-He213
650		4	\|a Biopsy \|7 (dpeaa)DE-He213
650		4	\|a Prostate-specific antigen \|7 (dpeaa)DE-He213
650		4	\|a MRI \|7 (dpeaa)DE-He213
650		4	\|a Gleason score \|7 (dpeaa)DE-He213
700	1		\|a Roupret, Morgan \|4 aut
700	1		\|a Compérat, Eva \|4 aut
700	1		\|a Rozet, François \|4 aut
700	1		\|a Granger, Benjamin \|4 aut
700	1		\|a Barkatz, Johann \|4 aut
700	1		\|a Bitker, Marc Olivier \|4 aut
700	1		\|a Lucidarme, Olivier \|4 aut
700	1		\|a Cussenot, Olivier \|4 aut
700	1		\|a Mozer, Pierre \|4 aut
773	0	8	\|i Enthalten in \|t World journal of urology \|d Berlin : Springer, 1983 \|g 34(2015), 5 vom: 24. Sept., Seite 673-678 \|w (DE-627)254910874 \|w (DE-600)1463303-6 \|x 1433-8726 \|7 nnns
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856	4	0	\|u https://dx.doi.org/10.1007/s00345-015-1685-2 \|z lizenzpflichtig \|3 Volltext
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912			\|a GBV_ILN_32
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_120
912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_152
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_250
912			\|a GBV_ILN_267
912			\|a GBV_ILN_281
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_702
912			\|a GBV_ILN_711
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2070
912			\|a GBV_ILN_2086
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2107
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2116
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2188
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2446
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2472
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_2548
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4046
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4246
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4328
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4336
912			\|a GBV_ILN_4338
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author_variant	r r p rrp m r mr e c ec f r fr b g bg j b jb m o b mo mob o l ol o c oc p m pm
matchkey_str	article:14338726:2015----::eainhpewennupcosradninfcnpottcners
hierarchy_sort_str	2015
publishDate	2015
allfields	10.1007/s00345-015-1685-2 doi (DE-627)SPR004316568 (SPR)s00345-015-1685-2-e DE-627 ger DE-627 rakwb eng Renard-Penna, Raphaële verfasserin aut Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213 Roupret, Morgan aut Compérat, Eva aut Rozet, François aut Granger, Benjamin aut Barkatz, Johann aut Bitker, Marc Olivier aut Lucidarme, Olivier aut Cussenot, Olivier aut Mozer, Pierre aut Enthalten in World journal of urology Berlin : Springer, 1983 34(2015), 5 vom: 24. Sept., Seite 673-678 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:34 year:2015 number:5 day:24 month:09 pages:673-678 https://dx.doi.org/10.1007/s00345-015-1685-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 34 2015 5 24 09 673-678
spelling	10.1007/s00345-015-1685-2 doi (DE-627)SPR004316568 (SPR)s00345-015-1685-2-e DE-627 ger DE-627 rakwb eng Renard-Penna, Raphaële verfasserin aut Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213 Roupret, Morgan aut Compérat, Eva aut Rozet, François aut Granger, Benjamin aut Barkatz, Johann aut Bitker, Marc Olivier aut Lucidarme, Olivier aut Cussenot, Olivier aut Mozer, Pierre aut Enthalten in World journal of urology Berlin : Springer, 1983 34(2015), 5 vom: 24. Sept., Seite 673-678 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:34 year:2015 number:5 day:24 month:09 pages:673-678 https://dx.doi.org/10.1007/s00345-015-1685-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 34 2015 5 24 09 673-678
allfields_unstemmed	10.1007/s00345-015-1685-2 doi (DE-627)SPR004316568 (SPR)s00345-015-1685-2-e DE-627 ger DE-627 rakwb eng Renard-Penna, Raphaële verfasserin aut Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213 Roupret, Morgan aut Compérat, Eva aut Rozet, François aut Granger, Benjamin aut Barkatz, Johann aut Bitker, Marc Olivier aut Lucidarme, Olivier aut Cussenot, Olivier aut Mozer, Pierre aut Enthalten in World journal of urology Berlin : Springer, 1983 34(2015), 5 vom: 24. Sept., Seite 673-678 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:34 year:2015 number:5 day:24 month:09 pages:673-678 https://dx.doi.org/10.1007/s00345-015-1685-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 34 2015 5 24 09 673-678
allfieldsGer	10.1007/s00345-015-1685-2 doi (DE-627)SPR004316568 (SPR)s00345-015-1685-2-e DE-627 ger DE-627 rakwb eng Renard-Penna, Raphaële verfasserin aut Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213 Roupret, Morgan aut Compérat, Eva aut Rozet, François aut Granger, Benjamin aut Barkatz, Johann aut Bitker, Marc Olivier aut Lucidarme, Olivier aut Cussenot, Olivier aut Mozer, Pierre aut Enthalten in World journal of urology Berlin : Springer, 1983 34(2015), 5 vom: 24. Sept., Seite 673-678 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:34 year:2015 number:5 day:24 month:09 pages:673-678 https://dx.doi.org/10.1007/s00345-015-1685-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 34 2015 5 24 09 673-678
allfieldsSound	10.1007/s00345-015-1685-2 doi (DE-627)SPR004316568 (SPR)s00345-015-1685-2-e DE-627 ger DE-627 rakwb eng Renard-Penna, Raphaële verfasserin aut Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier © Springer-Verlag Berlin Heidelberg 2015 Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213 Roupret, Morgan aut Compérat, Eva aut Rozet, François aut Granger, Benjamin aut Barkatz, Johann aut Bitker, Marc Olivier aut Lucidarme, Olivier aut Cussenot, Olivier aut Mozer, Pierre aut Enthalten in World journal of urology Berlin : Springer, 1983 34(2015), 5 vom: 24. Sept., Seite 673-678 (DE-627)254910874 (DE-600)1463303-6 1433-8726 nnns volume:34 year:2015 number:5 day:24 month:09 pages:673-678 https://dx.doi.org/10.1007/s00345-015-1685-2 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 34 2015 5 24 09 673-678
language	English
source	Enthalten in World journal of urology 34(2015), 5 vom: 24. Sept., Seite 673-678 volume:34 year:2015 number:5 day:24 month:09 pages:673-678
sourceStr	Enthalten in World journal of urology 34(2015), 5 vom: 24. Sept., Seite 673-678 volume:34 year:2015 number:5 day:24 month:09 pages:673-678
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Prostate neoplasms Biopsy Prostate-specific antigen MRI Gleason score
isfreeaccess_bool	false
container_title	World journal of urology
authorswithroles_txt_mv	Renard-Penna, Raphaële @@aut@@ Roupret, Morgan @@aut@@ Compérat, Eva @@aut@@ Rozet, François @@aut@@ Granger, Benjamin @@aut@@ Barkatz, Johann @@aut@@ Bitker, Marc Olivier @@aut@@ Lucidarme, Olivier @@aut@@ Cussenot, Olivier @@aut@@ Mozer, Pierre @@aut@@
publishDateDaySort_date	2015-09-24T00:00:00Z
hierarchy_top_id	254910874
id	SPR004316568
language_de	englisch
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PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. 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author	Renard-Penna, Raphaële
spellingShingle	Renard-Penna, Raphaële misc Prostate neoplasms misc Biopsy misc Prostate-specific antigen misc MRI misc Gleason score Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
authorStr	Renard-Penna, Raphaële
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topic_title	Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study Prostate neoplasms (dpeaa)DE-He213 Biopsy (dpeaa)DE-He213 Prostate-specific antigen (dpeaa)DE-He213 MRI (dpeaa)DE-He213 Gleason score (dpeaa)DE-He213
topic	misc Prostate neoplasms misc Biopsy misc Prostate-specific antigen misc MRI misc Gleason score
topic_unstemmed	misc Prostate neoplasms misc Biopsy misc Prostate-specific antigen misc MRI misc Gleason score
topic_browse	misc Prostate neoplasms misc Biopsy misc Prostate-specific antigen misc MRI misc Gleason score
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
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title	Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
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title_full	Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
author_sort	Renard-Penna, Raphaële
journal	World journal of urology
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container_start_page	673
author_browse	Renard-Penna, Raphaële Roupret, Morgan Compérat, Eva Rozet, François Granger, Benjamin Barkatz, Johann Bitker, Marc Olivier Lucidarme, Olivier Cussenot, Olivier Mozer, Pierre
container_volume	34
format_se	Elektronische Aufsätze
author-letter	Renard-Penna, Raphaële
doi_str_mv	10.1007/s00345-015-1685-2
title_sort	relationship between non-suspicious mri and insignificant prostate cancer: results from a monocentric study
title_auth	Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
abstract	Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. © Springer-Verlag Berlin Heidelberg 2015
abstractGer	Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. © Springer-Verlag Berlin Heidelberg 2015
abstract_unstemmed	Objectives To assess whether non-suspicious multiparametric magnetic-resonance imaging (mpMRI) was associated with no cancer or indolent prostate cancer (PCa) in subsequent biopsies. Patients and methods Retrospective analyses of a prospective database were conducted between 2009 and 2013. It included men with an abnormal digital rectal examination and/or prostate-specific antigen levels <20 ng/mL and a non-suspicious multiparametric MRI (Likert score <3). Participants underwent a systematic 12-extended-core biopsy ultrasound protocol (STD). Indolent PCa was defined as a single core with a Gleason score of 6 (3 + 3) and a cancer-core length of ≤4 mm. Results Seventy-eight patients with a negative MRI were included in the study; median patient age was 62 years (IQR 50–74). Median PSA level was 7.15 ng/mL, with a median PSA density of 0.15. The digital rectal examination was abnormal in eight cases. From MRI, 53 patients were Likert 2, 25 patients were Likert 1, and median prostate volume was 56.5 mL. From biopsies, no cancer was found in 92.3 % (n = 72). PCa was histologically confirmed in six patients (7.7 %): five cases were indolent (as defined above); only one patient had a cancer core of 5 mm long, with a Gleason score of 6 (3 + 3). All six patients were within the low-risk group according to the D’Amico classification. Conclusion Men with non-suspicious mpMRI are likely to have no or indolent PCa in subsequent biopsies. © Springer-Verlag Berlin Heidelberg 2015
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container_issue	5
title_short	Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study
url	https://dx.doi.org/10.1007/s00345-015-1685-2
remote_bool	true
author2	Roupret, Morgan Compérat, Eva Rozet, François Granger, Benjamin Barkatz, Johann Bitker, Marc Olivier Lucidarme, Olivier Cussenot, Olivier Mozer, Pierre
author2Str	Roupret, Morgan Compérat, Eva Rozet, François Granger, Benjamin Barkatz, Johann Bitker, Marc Olivier Lucidarme, Olivier Cussenot, Olivier Mozer, Pierre
ppnlink	254910874
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doi_str	10.1007/s00345-015-1685-2
up_date	2024-07-04T00:38:39.987Z
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Relationship between non-suspicious MRI and insignificant prostate cancer: results from a monocentric study

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