Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients
Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the s...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Chen, Xiao-Ping [verfasserIn] Qiu, Fa-Zu [verfasserIn] Lau, Wan-Yee [verfasserIn] Zhang, Bi-Xiang [verfasserIn] Chen, Yi-Fa [verfasserIn] Zhang, Wan-Guang [verfasserIn] He, Song-Qing [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2008 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: International journal of colorectal disease - Berlin : Springer, 1986, 23(2008), 5 vom: 09. Jan., Seite 543-546 |
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| Übergeordnetes Werk: |
volume:23 ; year:2008 ; number:5 ; day:09 ; month:01 ; pages:543-546 |
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| DOI / URN: |
10.1007/s00384-007-0411-y |
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| Katalog-ID: |
SPR004743725 |
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| 520 | |a Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. | ||
| 650 | 4 | |a Hepatocellular carcinoma |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Mesohepatectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Central hepatectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Middle hepatectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Survival |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Qiu, Fa-Zu |e verfasserin |4 aut | |
| 700 | 1 | |a Lau, Wan-Yee |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Bi-Xiang |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Yi-Fa |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Wan-Guang |e verfasserin |4 aut | |
| 700 | 1 | |a He, Song-Qing |e verfasserin |4 aut | |
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10.1007/s00384-007-0411-y doi (DE-627)SPR004743725 (SPR)s00384-007-0411-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Chen, Xiao-Ping verfasserin aut Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 Qiu, Fa-Zu verfasserin aut Lau, Wan-Yee verfasserin aut Zhang, Bi-Xiang verfasserin aut Chen, Yi-Fa verfasserin aut Zhang, Wan-Guang verfasserin aut He, Song-Qing verfasserin aut Enthalten in International journal of colorectal disease Berlin : Springer, 1986 23(2008), 5 vom: 09. Jan., Seite 543-546 (DE-627)253724244 (DE-600)1459217-4 1432-1262 nnns volume:23 year:2008 number:5 day:09 month:01 pages:543-546 https://dx.doi.org/10.1007/s00384-007-0411-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 23 2008 5 09 01 543-546 |
| spelling |
10.1007/s00384-007-0411-y doi (DE-627)SPR004743725 (SPR)s00384-007-0411-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Chen, Xiao-Ping verfasserin aut Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 Qiu, Fa-Zu verfasserin aut Lau, Wan-Yee verfasserin aut Zhang, Bi-Xiang verfasserin aut Chen, Yi-Fa verfasserin aut Zhang, Wan-Guang verfasserin aut He, Song-Qing verfasserin aut Enthalten in International journal of colorectal disease Berlin : Springer, 1986 23(2008), 5 vom: 09. Jan., Seite 543-546 (DE-627)253724244 (DE-600)1459217-4 1432-1262 nnns volume:23 year:2008 number:5 day:09 month:01 pages:543-546 https://dx.doi.org/10.1007/s00384-007-0411-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 23 2008 5 09 01 543-546 |
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10.1007/s00384-007-0411-y doi (DE-627)SPR004743725 (SPR)s00384-007-0411-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Chen, Xiao-Ping verfasserin aut Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 Qiu, Fa-Zu verfasserin aut Lau, Wan-Yee verfasserin aut Zhang, Bi-Xiang verfasserin aut Chen, Yi-Fa verfasserin aut Zhang, Wan-Guang verfasserin aut He, Song-Qing verfasserin aut Enthalten in International journal of colorectal disease Berlin : Springer, 1986 23(2008), 5 vom: 09. Jan., Seite 543-546 (DE-627)253724244 (DE-600)1459217-4 1432-1262 nnns volume:23 year:2008 number:5 day:09 month:01 pages:543-546 https://dx.doi.org/10.1007/s00384-007-0411-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 23 2008 5 09 01 543-546 |
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10.1007/s00384-007-0411-y doi (DE-627)SPR004743725 (SPR)s00384-007-0411-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Chen, Xiao-Ping verfasserin aut Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 Qiu, Fa-Zu verfasserin aut Lau, Wan-Yee verfasserin aut Zhang, Bi-Xiang verfasserin aut Chen, Yi-Fa verfasserin aut Zhang, Wan-Guang verfasserin aut He, Song-Qing verfasserin aut Enthalten in International journal of colorectal disease Berlin : Springer, 1986 23(2008), 5 vom: 09. Jan., Seite 543-546 (DE-627)253724244 (DE-600)1459217-4 1432-1262 nnns volume:23 year:2008 number:5 day:09 month:01 pages:543-546 https://dx.doi.org/10.1007/s00384-007-0411-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 23 2008 5 09 01 543-546 |
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10.1007/s00384-007-0411-y doi (DE-627)SPR004743725 (SPR)s00384-007-0411-y-e DE-627 ger DE-627 rakwb eng 610 ASE 44.87 bkl Chen, Xiao-Ping verfasserin aut Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 Qiu, Fa-Zu verfasserin aut Lau, Wan-Yee verfasserin aut Zhang, Bi-Xiang verfasserin aut Chen, Yi-Fa verfasserin aut Zhang, Wan-Guang verfasserin aut He, Song-Qing verfasserin aut Enthalten in International journal of colorectal disease Berlin : Springer, 1986 23(2008), 5 vom: 09. Jan., Seite 543-546 (DE-627)253724244 (DE-600)1459217-4 1432-1262 nnns volume:23 year:2008 number:5 day:09 month:01 pages:543-546 https://dx.doi.org/10.1007/s00384-007-0411-y lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.87 ASE AR 23 2008 5 09 01 543-546 |
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English |
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Enthalten in International journal of colorectal disease 23(2008), 5 vom: 09. Jan., Seite 543-546 volume:23 year:2008 number:5 day:09 month:01 pages:543-546 |
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Enthalten in International journal of colorectal disease 23(2008), 5 vom: 09. Jan., Seite 543-546 volume:23 year:2008 number:5 day:09 month:01 pages:543-546 |
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Hepatocellular carcinoma Mesohepatectomy Central hepatectomy Middle hepatectomy Survival |
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International journal of colorectal disease |
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Chen, Xiao-Ping @@aut@@ Qiu, Fa-Zu @@aut@@ Lau, Wan-Yee @@aut@@ Zhang, Bi-Xiang @@aut@@ Chen, Yi-Fa @@aut@@ Zhang, Wan-Guang @@aut@@ He, Song-Qing @@aut@@ |
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2008-01-09T00:00:00Z |
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In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. 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Chen, Xiao-Ping |
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Chen, Xiao-Ping ddc 610 bkl 44.87 misc Hepatocellular carcinoma misc Mesohepatectomy misc Central hepatectomy misc Middle hepatectomy misc Survival Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients |
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610 ASE 44.87 bkl Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients Hepatocellular carcinoma (dpeaa)DE-He213 Mesohepatectomy (dpeaa)DE-He213 Central hepatectomy (dpeaa)DE-He213 Middle hepatectomy (dpeaa)DE-He213 Survival (dpeaa)DE-He213 |
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ddc 610 bkl 44.87 misc Hepatocellular carcinoma misc Mesohepatectomy misc Central hepatectomy misc Middle hepatectomy misc Survival |
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ddc 610 bkl 44.87 misc Hepatocellular carcinoma misc Mesohepatectomy misc Central hepatectomy misc Middle hepatectomy misc Survival |
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International journal of colorectal disease |
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mesohepatectomy for hepatocellular carcinoma: a study of 256 patients |
| title_auth |
Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients |
| abstract |
Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. |
| abstractGer |
Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. |
| abstract_unstemmed |
Background Mesohepatectomy is a rarely used operative procedure to treat liver cancer because of its technical complexity. In patients with hepatocellular carcinoma (HCC) with a viral hepatitic/cirrhotic background, this procedure can be used to resect the tumor with adequate margins, while at the same time preserve as much functioning hepatic parenchyma as possible. This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC. Materials and methods From 1996 to 2005, 256 patients with HCC situated at the central liver segments (Couinaud segments IV, V, VIII ± I) were treated with mesohepatectomy. The treatment outcomes of these patients were retrospectively analyzed. Results The in-hospital mortality rate was 0.4%, but the postoperative morbidity rate was 28.1%. The 1-, 3-, and 5-year overall survival rates were 77.0, 49.8, and 35.1%, while the 1-, 3-, and 5-year disease-free survival rates were 59.1, 28.8, and 17.0%, respectively. Multivariate analyses showed the significant factors for overall survival were tumor size >8 cm, vascular invasion, and alpha fetoprotein (AFP) >5,000 ng/ml; and for disease-free survival were tumor size >8 cm, vascular invasion, tumor number (three or more), AFP >5,000 ng/ml. Conclusion Mesohepatectomy is a safe and effective treatment for a centrally situated HCC with a viral hepatitic/cirrhotic background. |
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| score |
7.3995953 |