Overall and cause-specific mortality in giant cell arteritis
Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, E...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Lee, Y. H. [verfasserIn] Song, G. G. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Zeitschrift für Rheumatologie - Steinkopff-Verlag, 1998, 77(2018), 10 vom: 20. März, Seite 946-951 |
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| Übergeordnetes Werk: |
volume:77 ; year:2018 ; number:10 ; day:20 ; month:03 ; pages:946-951 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00393-018-0440-7 |
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SPR004839218 |
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| 520 | |a Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. | ||
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10.1007/s00393-018-0440-7 doi (DE-627)SPR004839218 (SPR)s00393-018-0440-7-e DE-627 ger DE-627 rakwb eng Lee, Y. H. verfasserin aut Overall and cause-specific mortality in giant cell arteritis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. GCA (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Meta-analysis (dpeaa)DE-He213 Song, G. G. verfasserin aut Enthalten in Zeitschrift für Rheumatologie Steinkopff-Verlag, 1998 77(2018), 10 vom: 20. März, Seite 946-951 (DE-627)SPR004818482 nnns volume:77 year:2018 number:10 day:20 month:03 pages:946-951 https://dx.doi.org/10.1007/s00393-018-0440-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 77 2018 10 20 03 946-951 |
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10.1007/s00393-018-0440-7 doi (DE-627)SPR004839218 (SPR)s00393-018-0440-7-e DE-627 ger DE-627 rakwb eng Lee, Y. H. verfasserin aut Overall and cause-specific mortality in giant cell arteritis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. GCA (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Meta-analysis (dpeaa)DE-He213 Song, G. G. verfasserin aut Enthalten in Zeitschrift für Rheumatologie Steinkopff-Verlag, 1998 77(2018), 10 vom: 20. März, Seite 946-951 (DE-627)SPR004818482 nnns volume:77 year:2018 number:10 day:20 month:03 pages:946-951 https://dx.doi.org/10.1007/s00393-018-0440-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 77 2018 10 20 03 946-951 |
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10.1007/s00393-018-0440-7 doi (DE-627)SPR004839218 (SPR)s00393-018-0440-7-e DE-627 ger DE-627 rakwb eng Lee, Y. H. verfasserin aut Overall and cause-specific mortality in giant cell arteritis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. GCA (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Meta-analysis (dpeaa)DE-He213 Song, G. G. verfasserin aut Enthalten in Zeitschrift für Rheumatologie Steinkopff-Verlag, 1998 77(2018), 10 vom: 20. März, Seite 946-951 (DE-627)SPR004818482 nnns volume:77 year:2018 number:10 day:20 month:03 pages:946-951 https://dx.doi.org/10.1007/s00393-018-0440-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 77 2018 10 20 03 946-951 |
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10.1007/s00393-018-0440-7 doi (DE-627)SPR004839218 (SPR)s00393-018-0440-7-e DE-627 ger DE-627 rakwb eng Lee, Y. H. verfasserin aut Overall and cause-specific mortality in giant cell arteritis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. GCA (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Meta-analysis (dpeaa)DE-He213 Song, G. G. verfasserin aut Enthalten in Zeitschrift für Rheumatologie Steinkopff-Verlag, 1998 77(2018), 10 vom: 20. März, Seite 946-951 (DE-627)SPR004818482 nnns volume:77 year:2018 number:10 day:20 month:03 pages:946-951 https://dx.doi.org/10.1007/s00393-018-0440-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 77 2018 10 20 03 946-951 |
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10.1007/s00393-018-0440-7 doi (DE-627)SPR004839218 (SPR)s00393-018-0440-7-e DE-627 ger DE-627 rakwb eng Lee, Y. H. verfasserin aut Overall and cause-specific mortality in giant cell arteritis 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. GCA (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Meta-analysis (dpeaa)DE-He213 Song, G. G. verfasserin aut Enthalten in Zeitschrift für Rheumatologie Steinkopff-Verlag, 1998 77(2018), 10 vom: 20. März, Seite 946-951 (DE-627)SPR004818482 nnns volume:77 year:2018 number:10 day:20 month:03 pages:946-951 https://dx.doi.org/10.1007/s00393-018-0440-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA AR 77 2018 10 20 03 946-951 |
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Overall and cause-specific mortality in giant cell arteritis |
| abstract |
Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. |
| abstractGer |
Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. |
| abstract_unstemmed |
Objective This study aimed to assess the all-cause and cause-specific standardized mortality ratios (SMRs) in patients with giant cell arteritis (GCA). Methods We surveyed studies examining all-cause and/or cause-specific SMRs in patients with GCA compared to the general population, using MEDLINE, EMBASE, Cochrane databases, and manual searches. We then performed a meta-analysis of all-cause, sex-specific, region-specific, and cause-specific SMRs in patients with GCA. Results In total, 8 reports including 1972 patients with GCA (including 877 patients who died) met the inclusion criteria. Compared with the general population, all-cause SMR was not increased in patients with GCA (SMR 1.081, 95% confidence interval [CI] 0.963–1.214, p = 0.184). Stratification by region showed no significant increase in all-cause SMR in Europe and USA. Sex-specific meta-analysis revealed that the pooled SMR was 1.046 (95%CI 0.834–1.314, p = 0.696) for women and 1.051 (95%CI 0.974–1.133, p = 0.204) for men. There were no sex-specific significant differences in SMR. The risk of mortality due to cardiovascular disease (CVD) was significantly increased (SMR 1.312, 95%CI 1.136–1.516, p < 0.001). However, there was no significant increase in the SMR for mortality due to cancer (SMR 0.833, 95%CI 0.613–1.132, p = 0.243). Conclusions Patients with GCA do not show increased rates of death from all causes, regardless of sex, region, or malignancy. However, these patients are at an increased risk of death due to CVD. |
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GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA |
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10 |
| title_short |
Overall and cause-specific mortality in giant cell arteritis |
| url |
https://dx.doi.org/10.1007/s00393-018-0440-7 |
| remote_bool |
true |
| author2 |
Song, G. G. |
| author2Str |
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| doi_str |
10.1007/s00393-018-0440-7 |
| up_date |
2024-07-04T02:45:30.827Z |
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