Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study
Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study ass...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hendriksma, Martine [verfasserIn] van Loon, Yda [verfasserIn] Klop, W. Martin C. [verfasserIn] Hakkesteegt, Marieke M. [verfasserIn] Heijnen, Bas J. [verfasserIn] el Hasnaoui, Ibtissam [verfasserIn] de Jong, Martin [verfasserIn] Langeveld, Ton P. M. [verfasserIn] van Benthem, Peter Paul G. [verfasserIn] Baatenburg de Jong, Robert J. [verfasserIn] Sjögren, Elisabeth V. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: European archives of oto-rhino-laryngology and head & neck - Berlin : Springer, 1864, 276(2019), 3 vom: 27. Feb., Seite 805-814 |
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| Übergeordnetes Werk: |
volume:276 ; year:2019 ; number:3 ; day:27 ; month:02 ; pages:805-814 |
| Links: |
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| DOI / URN: |
10.1007/s00405-019-05348-1 |
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| Katalog-ID: |
SPR005217539 |
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| 245 | 1 | 0 | |a Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
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| 520 | |a Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. | ||
| 650 | 4 | |a Early glottic carcinoma |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a TLM |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Laser surgery |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Quality of life |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Voice outcome |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Questionnaire |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a van Loon, Yda |e verfasserin |4 aut | |
| 700 | 1 | |a Klop, W. Martin C. |e verfasserin |4 aut | |
| 700 | 1 | |a Hakkesteegt, Marieke M. |e verfasserin |4 aut | |
| 700 | 1 | |a Heijnen, Bas J. |e verfasserin |4 aut | |
| 700 | 1 | |a el Hasnaoui, Ibtissam |e verfasserin |4 aut | |
| 700 | 1 | |a de Jong, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Langeveld, Ton P. M. |e verfasserin |4 aut | |
| 700 | 1 | |a van Benthem, Peter Paul G. |e verfasserin |4 aut | |
| 700 | 1 | |a Baatenburg de Jong, Robert J. |e verfasserin |4 aut | |
| 700 | 1 | |a Sjögren, Elisabeth V. |e verfasserin |4 aut | |
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10.1007/s00405-019-05348-1 doi (DE-627)SPR005217539 (SPR)s00405-019-05348-1-e DE-627 ger DE-627 rakwb eng 610 ASE 44.94 bkl Hendriksma, Martine verfasserin aut Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 van Loon, Yda verfasserin aut Klop, W. Martin C. verfasserin aut Hakkesteegt, Marieke M. verfasserin aut Heijnen, Bas J. verfasserin aut el Hasnaoui, Ibtissam verfasserin aut de Jong, Martin verfasserin aut Langeveld, Ton P. M. verfasserin aut van Benthem, Peter Paul G. verfasserin aut Baatenburg de Jong, Robert J. verfasserin aut Sjögren, Elisabeth V. verfasserin aut Enthalten in European archives of oto-rhino-laryngology and head & neck Berlin : Springer, 1864 276(2019), 3 vom: 27. Feb., Seite 805-814 (DE-627)253722667 (DE-600)1459042-6 1434-4726 nnns volume:276 year:2019 number:3 day:27 month:02 pages:805-814 https://dx.doi.org/10.1007/s00405-019-05348-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.94 ASE AR 276 2019 3 27 02 805-814 |
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10.1007/s00405-019-05348-1 doi (DE-627)SPR005217539 (SPR)s00405-019-05348-1-e DE-627 ger DE-627 rakwb eng 610 ASE 44.94 bkl Hendriksma, Martine verfasserin aut Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 van Loon, Yda verfasserin aut Klop, W. Martin C. verfasserin aut Hakkesteegt, Marieke M. verfasserin aut Heijnen, Bas J. verfasserin aut el Hasnaoui, Ibtissam verfasserin aut de Jong, Martin verfasserin aut Langeveld, Ton P. M. verfasserin aut van Benthem, Peter Paul G. verfasserin aut Baatenburg de Jong, Robert J. verfasserin aut Sjögren, Elisabeth V. verfasserin aut Enthalten in European archives of oto-rhino-laryngology and head & neck Berlin : Springer, 1864 276(2019), 3 vom: 27. Feb., Seite 805-814 (DE-627)253722667 (DE-600)1459042-6 1434-4726 nnns volume:276 year:2019 number:3 day:27 month:02 pages:805-814 https://dx.doi.org/10.1007/s00405-019-05348-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.94 ASE AR 276 2019 3 27 02 805-814 |
| allfields_unstemmed |
10.1007/s00405-019-05348-1 doi (DE-627)SPR005217539 (SPR)s00405-019-05348-1-e DE-627 ger DE-627 rakwb eng 610 ASE 44.94 bkl Hendriksma, Martine verfasserin aut Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 van Loon, Yda verfasserin aut Klop, W. Martin C. verfasserin aut Hakkesteegt, Marieke M. verfasserin aut Heijnen, Bas J. verfasserin aut el Hasnaoui, Ibtissam verfasserin aut de Jong, Martin verfasserin aut Langeveld, Ton P. M. verfasserin aut van Benthem, Peter Paul G. verfasserin aut Baatenburg de Jong, Robert J. verfasserin aut Sjögren, Elisabeth V. verfasserin aut Enthalten in European archives of oto-rhino-laryngology and head & neck Berlin : Springer, 1864 276(2019), 3 vom: 27. Feb., Seite 805-814 (DE-627)253722667 (DE-600)1459042-6 1434-4726 nnns volume:276 year:2019 number:3 day:27 month:02 pages:805-814 https://dx.doi.org/10.1007/s00405-019-05348-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.94 ASE AR 276 2019 3 27 02 805-814 |
| allfieldsGer |
10.1007/s00405-019-05348-1 doi (DE-627)SPR005217539 (SPR)s00405-019-05348-1-e DE-627 ger DE-627 rakwb eng 610 ASE 44.94 bkl Hendriksma, Martine verfasserin aut Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 van Loon, Yda verfasserin aut Klop, W. Martin C. verfasserin aut Hakkesteegt, Marieke M. verfasserin aut Heijnen, Bas J. verfasserin aut el Hasnaoui, Ibtissam verfasserin aut de Jong, Martin verfasserin aut Langeveld, Ton P. M. verfasserin aut van Benthem, Peter Paul G. verfasserin aut Baatenburg de Jong, Robert J. verfasserin aut Sjögren, Elisabeth V. verfasserin aut Enthalten in European archives of oto-rhino-laryngology and head & neck Berlin : Springer, 1864 276(2019), 3 vom: 27. Feb., Seite 805-814 (DE-627)253722667 (DE-600)1459042-6 1434-4726 nnns volume:276 year:2019 number:3 day:27 month:02 pages:805-814 https://dx.doi.org/10.1007/s00405-019-05348-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.94 ASE AR 276 2019 3 27 02 805-814 |
| allfieldsSound |
10.1007/s00405-019-05348-1 doi (DE-627)SPR005217539 (SPR)s00405-019-05348-1-e DE-627 ger DE-627 rakwb eng 610 ASE 44.94 bkl Hendriksma, Martine verfasserin aut Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 van Loon, Yda verfasserin aut Klop, W. Martin C. verfasserin aut Hakkesteegt, Marieke M. verfasserin aut Heijnen, Bas J. verfasserin aut el Hasnaoui, Ibtissam verfasserin aut de Jong, Martin verfasserin aut Langeveld, Ton P. M. verfasserin aut van Benthem, Peter Paul G. verfasserin aut Baatenburg de Jong, Robert J. verfasserin aut Sjögren, Elisabeth V. verfasserin aut Enthalten in European archives of oto-rhino-laryngology and head & neck Berlin : Springer, 1864 276(2019), 3 vom: 27. Feb., Seite 805-814 (DE-627)253722667 (DE-600)1459042-6 1434-4726 nnns volume:276 year:2019 number:3 day:27 month:02 pages:805-814 https://dx.doi.org/10.1007/s00405-019-05348-1 kostenfrei Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.94 ASE AR 276 2019 3 27 02 805-814 |
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Enthalten in European archives of oto-rhino-laryngology and head & neck 276(2019), 3 vom: 27. Feb., Seite 805-814 volume:276 year:2019 number:3 day:27 month:02 pages:805-814 |
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Early glottic carcinoma TLM Laser surgery Quality of life Voice outcome Questionnaire |
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Hendriksma, Martine @@aut@@ van Loon, Yda @@aut@@ Klop, W. Martin C. @@aut@@ Hakkesteegt, Marieke M. @@aut@@ Heijnen, Bas J. @@aut@@ el Hasnaoui, Ibtissam @@aut@@ de Jong, Martin @@aut@@ Langeveld, Ton P. M. @@aut@@ van Benthem, Peter Paul G. @@aut@@ Baatenburg de Jong, Robert J. @@aut@@ Sjögren, Elisabeth V. @@aut@@ |
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2019-02-27T00:00:00Z |
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|
| author |
Hendriksma, Martine |
| spellingShingle |
Hendriksma, Martine ddc 610 bkl 44.94 misc Early glottic carcinoma misc TLM misc Laser surgery misc Quality of life misc Voice outcome misc Questionnaire Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
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1434-4726 |
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610 ASE 44.94 bkl Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study Early glottic carcinoma (dpeaa)DE-He213 TLM (dpeaa)DE-He213 Laser surgery (dpeaa)DE-He213 Quality of life (dpeaa)DE-He213 Voice outcome (dpeaa)DE-He213 Questionnaire (dpeaa)DE-He213 |
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ddc 610 bkl 44.94 misc Early glottic carcinoma misc TLM misc Laser surgery misc Quality of life misc Voice outcome misc Questionnaire |
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ddc 610 bkl 44.94 misc Early glottic carcinoma misc TLM misc Laser surgery misc Quality of life misc Voice outcome misc Questionnaire |
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ddc 610 bkl 44.94 misc Early glottic carcinoma misc TLM misc Laser surgery misc Quality of life misc Voice outcome misc Questionnaire |
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610 - Medicine & health |
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European archives of oto-rhino-laryngology and head & neck |
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Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
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(DE-627)SPR005217539 (SPR)s00405-019-05348-1-e |
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Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
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Hendriksma, Martine |
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European archives of oto-rhino-laryngology and head & neck |
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European archives of oto-rhino-laryngology and head & neck |
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eng |
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600 - Technology |
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2019 |
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Hendriksma, Martine van Loon, Yda Klop, W. Martin C. Hakkesteegt, Marieke M. Heijnen, Bas J. el Hasnaoui, Ibtissam de Jong, Martin Langeveld, Ton P. M. van Benthem, Peter Paul G. Baatenburg de Jong, Robert J. Sjögren, Elisabeth V. |
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610 ASE 44.94 bkl |
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Elektronische Aufsätze |
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Hendriksma, Martine |
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10.1007/s00405-019-05348-1 |
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610 |
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verfasserin |
| title_sort |
quality of life and voice outcome of patients treated with transoral $ co_{2} $ laser microsurgery for early glottic carcinoma (t1–t2): a 2-year follow-up study |
| title_auth |
Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
| abstract |
Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. |
| abstractGer |
Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. |
| abstract_unstemmed |
Purpose Longitudinal studies in laryngeal cancer can provide clinicians information about short-term and long-term functional outcomes, like quality of life (QoL) and voice outcome. This information is important when counseling patients or choosing a primary treatment modality. The present study assessed long-term (2 years) QoL and voice outcome in patients with extended T1 and limited T2 glottic carcinoma treated with transoral $ CO_{2} $ laser microsurgery (TLM) (unilateral type III or bilateral type II resections). Methods Three questionnaires were administered: the Voice Handicap Index (VHI), the European Organization for Research and Treatment of Cancer (EORTC) QoL questionnaire (QLQ)-C30, the EORTC QLQ-HN35. A perceptual voice evaluation at six different time points was conducted: preoperatively, and postoperatively at 6 weeks, 3 months, 6 months, 1 year, and 2 years. Fluctuations over time were investigated. Results Sixty-one patients were included in the analysis. Patients reported high-level functioning and low symptom scores 2 years postoperatively. Gender significantly affected the VHI scores at 2 years (mean VHI scores: female 8.7 vs. male, 23.9; p = 0.023). The major improvement in VHI scores was observed within the first 6 months. The tumor stage (T1a, T1b, and T2) significantly impacted the grade (mean scores at 2 years: 1.0, 1.9, and 1.7; p = 0.001). These scores stabilized at 6 months. Conclusions Patients show good long-term QoL with low symptom scores, a low voice handicap, and mild to moderate dysphonia, 2 years postoperatively. Scores stabilize at 6 months and provide a clear indication of status at 1 and 2 years. |
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| title_short |
Quality of life and voice outcome of patients treated with transoral $ CO_{2} $ laser microsurgery for early glottic carcinoma (T1–T2): a 2-year follow-up study |
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https://dx.doi.org/10.1007/s00405-019-05348-1 |
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van Loon, Yda Klop, W. Martin C. Hakkesteegt, Marieke M. Heijnen, Bas J. el Hasnaoui, Ibtissam de Jong, Martin Langeveld, Ton P. M. van Benthem, Peter Paul G. Baatenburg de Jong, Robert J. Sjögren, Elisabeth V. |
| author2Str |
van Loon, Yda Klop, W. Martin C. Hakkesteegt, Marieke M. Heijnen, Bas J. el Hasnaoui, Ibtissam de Jong, Martin Langeveld, Ton P. M. van Benthem, Peter Paul G. Baatenburg de Jong, Robert J. Sjögren, Elisabeth V. |
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| doi_str |
10.1007/s00405-019-05348-1 |
| up_date |
2024-07-03T14:48:57.580Z |
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| score |
7.400943 |