Glucose hypermetabolism in the thalamusof patients with essential blepharospasm
Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Suzuki, Y. [verfasserIn] Mizoguchi, S. [verfasserIn] Kiyosawa, M. [verfasserIn] Mochizuki, M. [verfasserIn] Ishiwata, K. [verfasserIn] Wakakura, M. [verfasserIn] Ishii, K. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2007 |
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| Übergeordnetes Werk: |
Enthalten in: Journal of neurology - [Darmstadt] : Steinkopff, 1891, 254(2007), 7 vom: 26. Feb., Seite 890-896 |
|---|---|
| Übergeordnetes Werk: |
volume:254 ; year:2007 ; number:7 ; day:26 ; month:02 ; pages:890-896 |
| Links: |
|---|
| DOI / URN: |
10.1007/s00415-006-0468-5 |
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| Katalog-ID: |
SPR005325900 |
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| 100 | 1 | |a Suzuki, Y. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Glucose hypermetabolism in the thalamusof patients with essential blepharospasm |
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| 520 | |a Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. | ||
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| 700 | 1 | |a Kiyosawa, M. |e verfasserin |4 aut | |
| 700 | 1 | |a Mochizuki, M. |e verfasserin |4 aut | |
| 700 | 1 | |a Ishiwata, K. |e verfasserin |4 aut | |
| 700 | 1 | |a Wakakura, M. |e verfasserin |4 aut | |
| 700 | 1 | |a Ishii, K. |e verfasserin |4 aut | |
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10.1007/s00415-006-0468-5 doi (DE-627)SPR005325900 (SPR)s00415-006-0468-5-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Suzuki, Y. verfasserin aut Glucose hypermetabolism in the thalamusof patients with essential blepharospasm 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. Mizoguchi, S. verfasserin aut Kiyosawa, M. verfasserin aut Mochizuki, M. verfasserin aut Ishiwata, K. verfasserin aut Wakakura, M. verfasserin aut Ishii, K. verfasserin aut Enthalten in Journal of neurology [Darmstadt] : Steinkopff, 1891 254(2007), 7 vom: 26. Feb., Seite 890-896 (DE-627)242065155 (DE-600)1421299-7 1432-1459 nnns volume:254 year:2007 number:7 day:26 month:02 pages:890-896 https://dx.doi.org/10.1007/s00415-006-0468-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_724 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 254 2007 7 26 02 890-896 |
| spelling |
10.1007/s00415-006-0468-5 doi (DE-627)SPR005325900 (SPR)s00415-006-0468-5-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Suzuki, Y. verfasserin aut Glucose hypermetabolism in the thalamusof patients with essential blepharospasm 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. Mizoguchi, S. verfasserin aut Kiyosawa, M. verfasserin aut Mochizuki, M. verfasserin aut Ishiwata, K. verfasserin aut Wakakura, M. verfasserin aut Ishii, K. verfasserin aut Enthalten in Journal of neurology [Darmstadt] : Steinkopff, 1891 254(2007), 7 vom: 26. Feb., Seite 890-896 (DE-627)242065155 (DE-600)1421299-7 1432-1459 nnns volume:254 year:2007 number:7 day:26 month:02 pages:890-896 https://dx.doi.org/10.1007/s00415-006-0468-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_724 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 254 2007 7 26 02 890-896 |
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10.1007/s00415-006-0468-5 doi (DE-627)SPR005325900 (SPR)s00415-006-0468-5-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Suzuki, Y. verfasserin aut Glucose hypermetabolism in the thalamusof patients with essential blepharospasm 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. Mizoguchi, S. verfasserin aut Kiyosawa, M. verfasserin aut Mochizuki, M. verfasserin aut Ishiwata, K. verfasserin aut Wakakura, M. verfasserin aut Ishii, K. verfasserin aut Enthalten in Journal of neurology [Darmstadt] : Steinkopff, 1891 254(2007), 7 vom: 26. Feb., Seite 890-896 (DE-627)242065155 (DE-600)1421299-7 1432-1459 nnns volume:254 year:2007 number:7 day:26 month:02 pages:890-896 https://dx.doi.org/10.1007/s00415-006-0468-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_724 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 254 2007 7 26 02 890-896 |
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10.1007/s00415-006-0468-5 doi (DE-627)SPR005325900 (SPR)s00415-006-0468-5-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Suzuki, Y. verfasserin aut Glucose hypermetabolism in the thalamusof patients with essential blepharospasm 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. Mizoguchi, S. verfasserin aut Kiyosawa, M. verfasserin aut Mochizuki, M. verfasserin aut Ishiwata, K. verfasserin aut Wakakura, M. verfasserin aut Ishii, K. verfasserin aut Enthalten in Journal of neurology [Darmstadt] : Steinkopff, 1891 254(2007), 7 vom: 26. Feb., Seite 890-896 (DE-627)242065155 (DE-600)1421299-7 1432-1459 nnns volume:254 year:2007 number:7 day:26 month:02 pages:890-896 https://dx.doi.org/10.1007/s00415-006-0468-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_724 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 254 2007 7 26 02 890-896 |
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10.1007/s00415-006-0468-5 doi (DE-627)SPR005325900 (SPR)s00415-006-0468-5-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.90 bkl Suzuki, Y. verfasserin aut Glucose hypermetabolism in the thalamusof patients with essential blepharospasm 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. Mizoguchi, S. verfasserin aut Kiyosawa, M. verfasserin aut Mochizuki, M. verfasserin aut Ishiwata, K. verfasserin aut Wakakura, M. verfasserin aut Ishii, K. verfasserin aut Enthalten in Journal of neurology [Darmstadt] : Steinkopff, 1891 254(2007), 7 vom: 26. Feb., Seite 890-896 (DE-627)242065155 (DE-600)1421299-7 1432-1459 nnns volume:254 year:2007 number:7 day:26 month:02 pages:890-896 https://dx.doi.org/10.1007/s00415-006-0468-5 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_724 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.90 ASE AR 254 2007 7 26 02 890-896 |
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Suzuki, Y. @@aut@@ Mizoguchi, S. @@aut@@ Kiyosawa, M. @@aut@@ Mochizuki, M. @@aut@@ Ishiwata, K. @@aut@@ Wakakura, M. @@aut@@ Ishii, K. @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR005325900</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519080450.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201001s2007 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00415-006-0468-5</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR005325900</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00415-006-0468-5-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.90</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Suzuki, Y.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Glucose hypermetabolism in the thalamusof patients with essential blepharospasm</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2007</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mizoguchi, S.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kiyosawa, M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mochizuki, M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ishiwata, K.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wakakura, M.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ishii, K.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of neurology</subfield><subfield code="d">[Darmstadt] : Steinkopff, 1891</subfield><subfield code="g">254(2007), 7 vom: 26. 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610 ASE 44.90 bkl Glucose hypermetabolism in the thalamusof patients with essential blepharospasm |
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Suzuki, Y. Mizoguchi, S. Kiyosawa, M. Mochizuki, M. Ishiwata, K. Wakakura, M. Ishii, K. |
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glucose hypermetabolism in the thalamusof patients with essential blepharospasm |
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Glucose hypermetabolism in the thalamusof patients with essential blepharospasm |
| abstract |
Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. |
| abstractGer |
Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. |
| abstract_unstemmed |
Abstract Essential blepharospasm(EB) is classified as a formof focal dystonia characterized byinvoluntary spasms of the musculatureof the upper face. The basicneurological process causing EB isnot known. The purpose of thisstudy was to investigate cerebralglucose metabolism in patientswith EB whose symptoms weresuppressed by an injection ofbotulinum-A toxin. Earlier studieswere confounded by sensoryfeedback activities derived fromdystonic symptom itself. Cerebralglucose metabolism was examinedby positron emission tomography(PET) with 18F-fluorodeoxyglucose(FDG) in 25 patients(8 men and 17 women; age52.6 ± 10.1 years) with EB. Thepatients were awake but with thespasms suppressed by an injectionof botulinum-A toxin. Thirty-eightnormal volunteers (14 men and 24women; age 58.2 ± 7.3 years) wereexamined as controls. The differencebetween the two groups wasexamined by statistical parametricmapping (SPM99). A significantincrease in the glucose metabolismwas detected in the thalamus andpons in the EB patients. Hyperactivityin the thalamus may be a keypathophysiological change commonto EB and other types of focaldystonia. The activity of the striatumand cerebellum are likely tobe sensory dependent. |
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| title_short |
Glucose hypermetabolism in the thalamusof patients with essential blepharospasm |
| url |
https://dx.doi.org/10.1007/s00415-006-0468-5 |
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| author2 |
Mizoguchi, S. Kiyosawa, M. Mochizuki, M. Ishiwata, K. Wakakura, M. Ishii, K. |
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Mizoguchi, S. Kiyosawa, M. Mochizuki, M. Ishiwata, K. Wakakura, M. Ishii, K. |
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10.1007/s00415-006-0468-5 |
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2024-07-03T15:33:09.646Z |
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| score |
7.4004736 |