Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico
Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Hernández, Marisela [verfasserIn] Astudillo, Osvaldo-Germán [verfasserIn] Diego, Gustavo [verfasserIn] de-la-Rosa-Arana, Jorge-Luis [verfasserIn] Meza-Lucas, Antonio [verfasserIn] García-Rodea, Ricardo [verfasserIn] Romo, Matthew-L. [verfasserIn] Toledo, Andrea [verfasserIn] Parkhouse, R.-Michael-E. [verfasserIn] Garate, Teresa [verfasserIn] Sciutto, Edda [verfasserIn] Fleury, Agnès [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Parasitology research - Berlin : Springer, 1928, 118(2019), 10 vom: 15. Aug., Seite 2891-2899 |
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| Übergeordnetes Werk: |
volume:118 ; year:2019 ; number:10 ; day:15 ; month:08 ; pages:2891-2899 |
| Links: |
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| DOI / URN: |
10.1007/s00436-019-06425-4 |
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| Katalog-ID: |
SPR005954886 |
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| 520 | |a Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. | ||
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| 650 | 4 | |a Immunodiagnosis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Mexico |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Neurocysticercosis |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Astudillo, Osvaldo-Germán |e verfasserin |4 aut | |
| 700 | 1 | |a Diego, Gustavo |e verfasserin |4 aut | |
| 700 | 1 | |a de-la-Rosa-Arana, Jorge-Luis |e verfasserin |4 aut | |
| 700 | 1 | |a Meza-Lucas, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a García-Rodea, Ricardo |e verfasserin |4 aut | |
| 700 | 1 | |a Romo, Matthew-L. |e verfasserin |4 aut | |
| 700 | 1 | |a Toledo, Andrea |e verfasserin |4 aut | |
| 700 | 1 | |a Parkhouse, R.-Michael-E. |e verfasserin |4 aut | |
| 700 | 1 | |a Garate, Teresa |e verfasserin |4 aut | |
| 700 | 1 | |a Sciutto, Edda |e verfasserin |4 aut | |
| 700 | 1 | |a Fleury, Agnès |e verfasserin |4 aut | |
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10.1007/s00436-019-06425-4 doi (DE-627)SPR005954886 (SPR)s00436-019-06425-4-e DE-627 ger DE-627 rakwb eng 590 610 ASE 44.44 bkl 42.00 bkl Hernández, Marisela verfasserin aut Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 Astudillo, Osvaldo-Germán verfasserin aut Diego, Gustavo verfasserin aut de-la-Rosa-Arana, Jorge-Luis verfasserin aut Meza-Lucas, Antonio verfasserin aut García-Rodea, Ricardo verfasserin aut Romo, Matthew-L. verfasserin aut Toledo, Andrea verfasserin aut Parkhouse, R.-Michael-E. verfasserin aut Garate, Teresa verfasserin aut Sciutto, Edda verfasserin aut Fleury, Agnès verfasserin aut Enthalten in Parasitology research Berlin : Springer, 1928 118(2019), 10 vom: 15. Aug., Seite 2891-2899 (DE-627)254638627 (DE-600)1462976-8 1432-1955 nnns volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 https://dx.doi.org/10.1007/s00436-019-06425-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.44 ASE 42.00 ASE AR 118 2019 10 15 08 2891-2899 |
| spelling |
10.1007/s00436-019-06425-4 doi (DE-627)SPR005954886 (SPR)s00436-019-06425-4-e DE-627 ger DE-627 rakwb eng 590 610 ASE 44.44 bkl 42.00 bkl Hernández, Marisela verfasserin aut Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 Astudillo, Osvaldo-Germán verfasserin aut Diego, Gustavo verfasserin aut de-la-Rosa-Arana, Jorge-Luis verfasserin aut Meza-Lucas, Antonio verfasserin aut García-Rodea, Ricardo verfasserin aut Romo, Matthew-L. verfasserin aut Toledo, Andrea verfasserin aut Parkhouse, R.-Michael-E. verfasserin aut Garate, Teresa verfasserin aut Sciutto, Edda verfasserin aut Fleury, Agnès verfasserin aut Enthalten in Parasitology research Berlin : Springer, 1928 118(2019), 10 vom: 15. Aug., Seite 2891-2899 (DE-627)254638627 (DE-600)1462976-8 1432-1955 nnns volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 https://dx.doi.org/10.1007/s00436-019-06425-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.44 ASE 42.00 ASE AR 118 2019 10 15 08 2891-2899 |
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10.1007/s00436-019-06425-4 doi (DE-627)SPR005954886 (SPR)s00436-019-06425-4-e DE-627 ger DE-627 rakwb eng 590 610 ASE 44.44 bkl 42.00 bkl Hernández, Marisela verfasserin aut Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 Astudillo, Osvaldo-Germán verfasserin aut Diego, Gustavo verfasserin aut de-la-Rosa-Arana, Jorge-Luis verfasserin aut Meza-Lucas, Antonio verfasserin aut García-Rodea, Ricardo verfasserin aut Romo, Matthew-L. verfasserin aut Toledo, Andrea verfasserin aut Parkhouse, R.-Michael-E. verfasserin aut Garate, Teresa verfasserin aut Sciutto, Edda verfasserin aut Fleury, Agnès verfasserin aut Enthalten in Parasitology research Berlin : Springer, 1928 118(2019), 10 vom: 15. Aug., Seite 2891-2899 (DE-627)254638627 (DE-600)1462976-8 1432-1955 nnns volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 https://dx.doi.org/10.1007/s00436-019-06425-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.44 ASE 42.00 ASE AR 118 2019 10 15 08 2891-2899 |
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10.1007/s00436-019-06425-4 doi (DE-627)SPR005954886 (SPR)s00436-019-06425-4-e DE-627 ger DE-627 rakwb eng 590 610 ASE 44.44 bkl 42.00 bkl Hernández, Marisela verfasserin aut Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 Astudillo, Osvaldo-Germán verfasserin aut Diego, Gustavo verfasserin aut de-la-Rosa-Arana, Jorge-Luis verfasserin aut Meza-Lucas, Antonio verfasserin aut García-Rodea, Ricardo verfasserin aut Romo, Matthew-L. verfasserin aut Toledo, Andrea verfasserin aut Parkhouse, R.-Michael-E. verfasserin aut Garate, Teresa verfasserin aut Sciutto, Edda verfasserin aut Fleury, Agnès verfasserin aut Enthalten in Parasitology research Berlin : Springer, 1928 118(2019), 10 vom: 15. Aug., Seite 2891-2899 (DE-627)254638627 (DE-600)1462976-8 1432-1955 nnns volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 https://dx.doi.org/10.1007/s00436-019-06425-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.44 ASE 42.00 ASE AR 118 2019 10 15 08 2891-2899 |
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10.1007/s00436-019-06425-4 doi (DE-627)SPR005954886 (SPR)s00436-019-06425-4-e DE-627 ger DE-627 rakwb eng 590 610 ASE 44.44 bkl 42.00 bkl Hernández, Marisela verfasserin aut Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 Astudillo, Osvaldo-Germán verfasserin aut Diego, Gustavo verfasserin aut de-la-Rosa-Arana, Jorge-Luis verfasserin aut Meza-Lucas, Antonio verfasserin aut García-Rodea, Ricardo verfasserin aut Romo, Matthew-L. verfasserin aut Toledo, Andrea verfasserin aut Parkhouse, R.-Michael-E. verfasserin aut Garate, Teresa verfasserin aut Sciutto, Edda verfasserin aut Fleury, Agnès verfasserin aut Enthalten in Parasitology research Berlin : Springer, 1928 118(2019), 10 vom: 15. Aug., Seite 2891-2899 (DE-627)254638627 (DE-600)1462976-8 1432-1955 nnns volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 https://dx.doi.org/10.1007/s00436-019-06425-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.44 ASE 42.00 ASE AR 118 2019 10 15 08 2891-2899 |
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Enthalten in Parasitology research 118(2019), 10 vom: 15. Aug., Seite 2891-2899 volume:118 year:2019 number:10 day:15 month:08 pages:2891-2899 |
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ELISA EITB HP10 Immunodiagnosis Mexico Neurocysticercosis |
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Hernández, Marisela @@aut@@ Astudillo, Osvaldo-Germán @@aut@@ Diego, Gustavo @@aut@@ de-la-Rosa-Arana, Jorge-Luis @@aut@@ Meza-Lucas, Antonio @@aut@@ García-Rodea, Ricardo @@aut@@ Romo, Matthew-L. @@aut@@ Toledo, Andrea @@aut@@ Parkhouse, R.-Michael-E. @@aut@@ Garate, Teresa @@aut@@ Sciutto, Edda @@aut@@ Fleury, Agnès @@aut@@ |
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2019-08-15T00:00:00Z |
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|
| author |
Hernández, Marisela |
| spellingShingle |
Hernández, Marisela ddc 590 bkl 44.44 bkl 42.00 misc ELISA misc EITB misc HP10 misc Immunodiagnosis misc Mexico misc Neurocysticercosis Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico |
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Hernández, Marisela |
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electronic Article |
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590 - Animals (Zoology) 610 - Medicine & health |
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keep |
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aut aut aut aut aut aut aut aut aut aut aut aut |
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springer |
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true |
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Not Illustrated |
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1432-1955 |
| topic_title |
590 610 ASE 44.44 bkl 42.00 bkl Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico ELISA (dpeaa)DE-He213 EITB (dpeaa)DE-He213 HP10 (dpeaa)DE-He213 Immunodiagnosis (dpeaa)DE-He213 Mexico (dpeaa)DE-He213 Neurocysticercosis (dpeaa)DE-He213 |
| topic |
ddc 590 bkl 44.44 bkl 42.00 misc ELISA misc EITB misc HP10 misc Immunodiagnosis misc Mexico misc Neurocysticercosis |
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ddc 590 bkl 44.44 bkl 42.00 misc ELISA misc EITB misc HP10 misc Immunodiagnosis misc Mexico misc Neurocysticercosis |
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ddc 590 bkl 44.44 bkl 42.00 misc ELISA misc EITB misc HP10 misc Immunodiagnosis misc Mexico misc Neurocysticercosis |
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Elektronische Aufsätze Aufsätze Elektronische Ressource |
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Parasitology research |
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Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico |
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Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico |
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Hernández, Marisela |
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Hernández, Marisela Astudillo, Osvaldo-Germán Diego, Gustavo de-la-Rosa-Arana, Jorge-Luis Meza-Lucas, Antonio García-Rodea, Ricardo Romo, Matthew-L. Toledo, Andrea Parkhouse, R.-Michael-E. Garate, Teresa Sciutto, Edda Fleury, Agnès |
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Hernández, Marisela |
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immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in mexico |
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Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico |
| abstract |
Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. |
| abstractGer |
Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. |
| abstract_unstemmed |
Abstract Immunodiagnosis has a supportive role in the diagnosis of neurocysticercosis (NCC). The aim of this study was to compare the validity of seven immunodiagnostic tests among serum samples from 58 patients with NCC, 26 patients with neurological diseases other than NCC, and 15 healthy controls. One test for viable parasite detection (HP10 antigen assay) and six for antibody detection were evaluated. For the entire sample, sensitivities ranged from 55.2% (NOVALISA) to 81.0% (enzyme-linked immunosorbent assay [ELISA] Taenia solium antibody), with the sensitivity of the latter test significantly higher than that of the in-house ELISA Taenia crassiceps, NOVALISA, enzyme-linked immunoelectrotransfer blot (EITB) CDC, and HP10. Overall, specificities were high, ranging from 85.4% (ELISA Ts) to 97.1% (NOVALISA), with no statistically significant differences. Detection of HP10 antigen was significantly associated with the presence of vesicular parasites. The simple and low-cost ELISA Taenia solium antibody Ab instead of EITB is recommended to support NCC diagnosis in both rural and hospital settings in Mexico. |
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Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico |
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Astudillo, Osvaldo-Germán Diego, Gustavo de-la-Rosa-Arana, Jorge-Luis Meza-Lucas, Antonio García-Rodea, Ricardo Romo, Matthew-L. Toledo, Andrea Parkhouse, R.-Michael-E. Garate, Teresa Sciutto, Edda Fleury, Agnès |
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Astudillo, Osvaldo-Germán Diego, Gustavo de-la-Rosa-Arana, Jorge-Luis Meza-Lucas, Antonio García-Rodea, Ricardo Romo, Matthew-L. Toledo, Andrea Parkhouse, R.-Michael-E. Garate, Teresa Sciutto, Edda Fleury, Agnès |
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| score |
7.399441 |