Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study
Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Rees, Jordan L. [verfasserIn] Chang, Courtney R. [verfasserIn] François, Monique E. [verfasserIn] Marcotte-Chénard, Alexis [verfasserIn] Fontvieille, Adeline [verfasserIn] Klaprat, Nika D. [verfasserIn] Dyck, Rebecca A. [verfasserIn] Funk, Deanna R. [verfasserIn] Snydmiller, Gary [verfasserIn] Bastell, Kent [verfasserIn] Godkin, Florence E. [verfasserIn] Dubé, Marie-Christine [verfasserIn] Riesco, Eléonor [verfasserIn] McGavock, Jon M. [verfasserIn] Yardley, Jane E. [verfasserIn] Sigal, Ronald J. [verfasserIn] Gibala, Martin J. [verfasserIn] Weisnagel, S. John [verfasserIn] Prado, Carla M. [verfasserIn] Jung, Mary [verfasserIn] Manders, Ralph [verfasserIn] Lee, Terry [verfasserIn] Singer, Joel [verfasserIn] Boulé, Normand G. [verfasserIn] Little, Jonathan P. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Acta diabetologica - Mailand : Springer, 1964, 56(2019), 7 vom: 15. Mai, Seite 755-765 |
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| Übergeordnetes Werk: |
volume:56 ; year:2019 ; number:7 ; day:15 ; month:05 ; pages:755-765 |
| Links: |
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| DOI / URN: |
10.1007/s00592-019-01358-x |
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| Katalog-ID: |
SPR007003323 |
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| 100 | 1 | |a Rees, Jordan L. |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study |
| 264 | 1 | |c 2019 | |
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| 520 | |a Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. | ||
| 650 | 4 | |a Continuous glucose monitoring |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Glycemic control |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Type 2 diabetes |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Physical activity |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Walking |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Chang, Courtney R. |e verfasserin |4 aut | |
| 700 | 1 | |a François, Monique E. |e verfasserin |4 aut | |
| 700 | 1 | |a Marcotte-Chénard, Alexis |e verfasserin |4 aut | |
| 700 | 1 | |a Fontvieille, Adeline |e verfasserin |4 aut | |
| 700 | 1 | |a Klaprat, Nika D. |e verfasserin |4 aut | |
| 700 | 1 | |a Dyck, Rebecca A. |e verfasserin |4 aut | |
| 700 | 1 | |a Funk, Deanna R. |e verfasserin |4 aut | |
| 700 | 1 | |a Snydmiller, Gary |e verfasserin |4 aut | |
| 700 | 1 | |a Bastell, Kent |e verfasserin |4 aut | |
| 700 | 1 | |a Godkin, Florence E. |e verfasserin |4 aut | |
| 700 | 1 | |a Dubé, Marie-Christine |e verfasserin |4 aut | |
| 700 | 1 | |a Riesco, Eléonor |e verfasserin |4 aut | |
| 700 | 1 | |a McGavock, Jon M. |e verfasserin |4 aut | |
| 700 | 1 | |a Yardley, Jane E. |e verfasserin |4 aut | |
| 700 | 1 | |a Sigal, Ronald J. |e verfasserin |4 aut | |
| 700 | 1 | |a Gibala, Martin J. |e verfasserin |4 aut | |
| 700 | 1 | |a Weisnagel, S. John |e verfasserin |4 aut | |
| 700 | 1 | |a Prado, Carla M. |e verfasserin |4 aut | |
| 700 | 1 | |a Jung, Mary |e verfasserin |4 aut | |
| 700 | 1 | |a Manders, Ralph |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Terry |e verfasserin |4 aut | |
| 700 | 1 | |a Singer, Joel |e verfasserin |4 aut | |
| 700 | 1 | |a Boulé, Normand G. |e verfasserin |4 aut | |
| 700 | 1 | |a Little, Jonathan P. |e verfasserin |4 aut | |
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10.1007/s00592-019-01358-x doi (DE-627)SPR007003323 (SPR)s00592-019-01358-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.89 bkl Rees, Jordan L. verfasserin aut Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 Chang, Courtney R. verfasserin aut François, Monique E. verfasserin aut Marcotte-Chénard, Alexis verfasserin aut Fontvieille, Adeline verfasserin aut Klaprat, Nika D. verfasserin aut Dyck, Rebecca A. verfasserin aut Funk, Deanna R. verfasserin aut Snydmiller, Gary verfasserin aut Bastell, Kent verfasserin aut Godkin, Florence E. verfasserin aut Dubé, Marie-Christine verfasserin aut Riesco, Eléonor verfasserin aut McGavock, Jon M. verfasserin aut Yardley, Jane E. verfasserin aut Sigal, Ronald J. verfasserin aut Gibala, Martin J. verfasserin aut Weisnagel, S. John verfasserin aut Prado, Carla M. verfasserin aut Jung, Mary verfasserin aut Manders, Ralph verfasserin aut Lee, Terry verfasserin aut Singer, Joel verfasserin aut Boulé, Normand G. verfasserin aut Little, Jonathan P. verfasserin aut Enthalten in Acta diabetologica Mailand : Springer, 1964 56(2019), 7 vom: 15. Mai, Seite 755-765 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:56 year:2019 number:7 day:15 month:05 pages:755-765 https://dx.doi.org/10.1007/s00592-019-01358-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.89 ASE AR 56 2019 7 15 05 755-765 |
| spelling |
10.1007/s00592-019-01358-x doi (DE-627)SPR007003323 (SPR)s00592-019-01358-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.89 bkl Rees, Jordan L. verfasserin aut Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 Chang, Courtney R. verfasserin aut François, Monique E. verfasserin aut Marcotte-Chénard, Alexis verfasserin aut Fontvieille, Adeline verfasserin aut Klaprat, Nika D. verfasserin aut Dyck, Rebecca A. verfasserin aut Funk, Deanna R. verfasserin aut Snydmiller, Gary verfasserin aut Bastell, Kent verfasserin aut Godkin, Florence E. verfasserin aut Dubé, Marie-Christine verfasserin aut Riesco, Eléonor verfasserin aut McGavock, Jon M. verfasserin aut Yardley, Jane E. verfasserin aut Sigal, Ronald J. verfasserin aut Gibala, Martin J. verfasserin aut Weisnagel, S. John verfasserin aut Prado, Carla M. verfasserin aut Jung, Mary verfasserin aut Manders, Ralph verfasserin aut Lee, Terry verfasserin aut Singer, Joel verfasserin aut Boulé, Normand G. verfasserin aut Little, Jonathan P. verfasserin aut Enthalten in Acta diabetologica Mailand : Springer, 1964 56(2019), 7 vom: 15. Mai, Seite 755-765 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:56 year:2019 number:7 day:15 month:05 pages:755-765 https://dx.doi.org/10.1007/s00592-019-01358-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.89 ASE AR 56 2019 7 15 05 755-765 |
| allfields_unstemmed |
10.1007/s00592-019-01358-x doi (DE-627)SPR007003323 (SPR)s00592-019-01358-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.89 bkl Rees, Jordan L. verfasserin aut Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 Chang, Courtney R. verfasserin aut François, Monique E. verfasserin aut Marcotte-Chénard, Alexis verfasserin aut Fontvieille, Adeline verfasserin aut Klaprat, Nika D. verfasserin aut Dyck, Rebecca A. verfasserin aut Funk, Deanna R. verfasserin aut Snydmiller, Gary verfasserin aut Bastell, Kent verfasserin aut Godkin, Florence E. verfasserin aut Dubé, Marie-Christine verfasserin aut Riesco, Eléonor verfasserin aut McGavock, Jon M. verfasserin aut Yardley, Jane E. verfasserin aut Sigal, Ronald J. verfasserin aut Gibala, Martin J. verfasserin aut Weisnagel, S. John verfasserin aut Prado, Carla M. verfasserin aut Jung, Mary verfasserin aut Manders, Ralph verfasserin aut Lee, Terry verfasserin aut Singer, Joel verfasserin aut Boulé, Normand G. verfasserin aut Little, Jonathan P. verfasserin aut Enthalten in Acta diabetologica Mailand : Springer, 1964 56(2019), 7 vom: 15. Mai, Seite 755-765 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:56 year:2019 number:7 day:15 month:05 pages:755-765 https://dx.doi.org/10.1007/s00592-019-01358-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.89 ASE AR 56 2019 7 15 05 755-765 |
| allfieldsGer |
10.1007/s00592-019-01358-x doi (DE-627)SPR007003323 (SPR)s00592-019-01358-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.89 bkl Rees, Jordan L. verfasserin aut Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 Chang, Courtney R. verfasserin aut François, Monique E. verfasserin aut Marcotte-Chénard, Alexis verfasserin aut Fontvieille, Adeline verfasserin aut Klaprat, Nika D. verfasserin aut Dyck, Rebecca A. verfasserin aut Funk, Deanna R. verfasserin aut Snydmiller, Gary verfasserin aut Bastell, Kent verfasserin aut Godkin, Florence E. verfasserin aut Dubé, Marie-Christine verfasserin aut Riesco, Eléonor verfasserin aut McGavock, Jon M. verfasserin aut Yardley, Jane E. verfasserin aut Sigal, Ronald J. verfasserin aut Gibala, Martin J. verfasserin aut Weisnagel, S. John verfasserin aut Prado, Carla M. verfasserin aut Jung, Mary verfasserin aut Manders, Ralph verfasserin aut Lee, Terry verfasserin aut Singer, Joel verfasserin aut Boulé, Normand G. verfasserin aut Little, Jonathan P. verfasserin aut Enthalten in Acta diabetologica Mailand : Springer, 1964 56(2019), 7 vom: 15. Mai, Seite 755-765 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:56 year:2019 number:7 day:15 month:05 pages:755-765 https://dx.doi.org/10.1007/s00592-019-01358-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.89 ASE AR 56 2019 7 15 05 755-765 |
| allfieldsSound |
10.1007/s00592-019-01358-x doi (DE-627)SPR007003323 (SPR)s00592-019-01358-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.89 bkl Rees, Jordan L. verfasserin aut Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 Chang, Courtney R. verfasserin aut François, Monique E. verfasserin aut Marcotte-Chénard, Alexis verfasserin aut Fontvieille, Adeline verfasserin aut Klaprat, Nika D. verfasserin aut Dyck, Rebecca A. verfasserin aut Funk, Deanna R. verfasserin aut Snydmiller, Gary verfasserin aut Bastell, Kent verfasserin aut Godkin, Florence E. verfasserin aut Dubé, Marie-Christine verfasserin aut Riesco, Eléonor verfasserin aut McGavock, Jon M. verfasserin aut Yardley, Jane E. verfasserin aut Sigal, Ronald J. verfasserin aut Gibala, Martin J. verfasserin aut Weisnagel, S. John verfasserin aut Prado, Carla M. verfasserin aut Jung, Mary verfasserin aut Manders, Ralph verfasserin aut Lee, Terry verfasserin aut Singer, Joel verfasserin aut Boulé, Normand G. verfasserin aut Little, Jonathan P. verfasserin aut Enthalten in Acta diabetologica Mailand : Springer, 1964 56(2019), 7 vom: 15. Mai, Seite 755-765 (DE-627)266886469 (DE-600)1468518-8 1432-5233 nnns volume:56 year:2019 number:7 day:15 month:05 pages:755-765 https://dx.doi.org/10.1007/s00592-019-01358-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.89 ASE AR 56 2019 7 15 05 755-765 |
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Enthalten in Acta diabetologica 56(2019), 7 vom: 15. Mai, Seite 755-765 volume:56 year:2019 number:7 day:15 month:05 pages:755-765 |
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Continuous glucose monitoring Glycemic control Type 2 diabetes Physical activity Walking |
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Rees, Jordan L. @@aut@@ Chang, Courtney R. @@aut@@ François, Monique E. @@aut@@ Marcotte-Chénard, Alexis @@aut@@ Fontvieille, Adeline @@aut@@ Klaprat, Nika D. @@aut@@ Dyck, Rebecca A. @@aut@@ Funk, Deanna R. @@aut@@ Snydmiller, Gary @@aut@@ Bastell, Kent @@aut@@ Godkin, Florence E. @@aut@@ Dubé, Marie-Christine @@aut@@ Riesco, Eléonor @@aut@@ McGavock, Jon M. @@aut@@ Yardley, Jane E. @@aut@@ Sigal, Ronald J. @@aut@@ Gibala, Martin J. @@aut@@ Weisnagel, S. John @@aut@@ Prado, Carla M. @@aut@@ Jung, Mary @@aut@@ Manders, Ralph @@aut@@ Lee, Terry @@aut@@ Singer, Joel @@aut@@ Boulé, Normand G. @@aut@@ Little, Jonathan P. @@aut@@ |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR007003323</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519193932.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201005s2019 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00592-019-01358-x</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR007003323</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00592-019-01358-x-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.89</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Rees, Jordan L.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. 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610 ASE 44.89 bkl Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study Continuous glucose monitoring (dpeaa)DE-He213 Glycemic control (dpeaa)DE-He213 Type 2 diabetes (dpeaa)DE-He213 Physical activity (dpeaa)DE-He213 Walking (dpeaa)DE-He213 |
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Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study |
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Rees, Jordan L. Chang, Courtney R. François, Monique E. Marcotte-Chénard, Alexis Fontvieille, Adeline Klaprat, Nika D. Dyck, Rebecca A. Funk, Deanna R. Snydmiller, Gary Bastell, Kent Godkin, Florence E. Dubé, Marie-Christine Riesco, Eléonor McGavock, Jon M. Yardley, Jane E. Sigal, Ronald J. Gibala, Martin J. Weisnagel, S. John Prado, Carla M. Jung, Mary Manders, Ralph Lee, Terry Singer, Joel Boulé, Normand G. Little, Jonathan P. |
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minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site e-paradigm study |
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Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study |
| abstract |
Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. |
| abstractGer |
Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. |
| abstract_unstemmed |
Aim To examine the effect of walking before dinner on 24-h glycemic control in individuals with type 2 diabetes using the standardized multi-site Exercise-Physical Activity and Diabetes Glucose Monitoring (E-PAraDiGM) Protocol. Methods Eighty participants were studied under two conditions (exercise vs. non-exercise control) separated by 72 h in a randomized crossover design. Each condition lasted 2 days during which standardized meals were provided. Exercise consisted of 50 min of treadmill walking at 5.0 km/h before the evening meal, while control involved 50 min of sitting. The primary outcome measure was mean glucose during the 24-h period following exercise (or sitting) measured by continuous glucose monitoring. Results Of the 80 participants who were initially randomized, 73 completed both exercise and control. Sixty-three participants [29 males, 34 females; age = 64 ± 8 years, body mass index = 30.5 ± 6.5 kg/$ m^{2} $ and HbA1c = 51 ± 8 mmol/mol (6.8 ± 0.7%), mean ± SD] complied with the standardized diets and had complete continuous glucose monitoring data. Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. Trial registration: NCT02834689. |
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Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study |
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Exercise did not affect mean 24-h glucose compared to control (0.03 mmol/L; 95% CI − 0.17, 0.22, P = 0.778) but individual differences between conditions ranged from − 2.8 to +1.8 mmol/L. Exercise did not affect fasting glucose, postprandial glucose or glucose variability. Glucose concentrations measured by continuous glucose monitoring were reduced during the 50 min of walking in exercise compared to sitting in control (− 1.56 mmol/L; 95% CI − 2.18, − 0.95, p < 0.001). Conclusion Contrary to previous acute exercise studies, 50 min of walking before dinner in the E-PAraDiGM protocol did not affect 24-h glucose profiles. However, highly heterogeneous responses to exercise were observed. 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7.400055 |