The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma
Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Resu...
Ausführliche Beschreibung
Autor*in: |
Matsunaga, Tomoyuki [verfasserIn] Saito, Hiroaki [verfasserIn] Fukumoto, Yoji [verfasserIn] Shimizu, Shota [verfasserIn] Kono, Yusuke [verfasserIn] Murakami, Yuki [verfasserIn] Shishido, Yuji [verfasserIn] Miyatani, Kozo [verfasserIn] Yamamoto, Manabu [verfasserIn] Tokuyasu, Naruo [verfasserIn] Takano, Shuichi [verfasserIn] Sakamoto, Teruhisa [verfasserIn] Honjo, Soichiro [verfasserIn] Fujiwara, Yoshiyuki [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Surgery today - Tokyo : Springer, 1971, 50(2019), 2 vom: 06. Aug., Seite 123-133 |
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Übergeordnetes Werk: |
volume:50 ; year:2019 ; number:2 ; day:06 ; month:08 ; pages:123-133 |
Links: |
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DOI / URN: |
10.1007/s00595-019-01860-3 |
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Katalog-ID: |
SPR007039328 |
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100 | 1 | |a Matsunaga, Tomoyuki |e verfasserin |4 aut | |
245 | 1 | 4 | |a The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
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520 | |a Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. | ||
650 | 4 | |a Esophageal cancer |7 (dpeaa)DE-He213 | |
650 | 4 | |a Platelet distribution width |7 (dpeaa)DE-He213 | |
650 | 4 | |a Prognosis |7 (dpeaa)DE-He213 | |
650 | 4 | |a Recurrence |7 (dpeaa)DE-He213 | |
700 | 1 | |a Saito, Hiroaki |e verfasserin |4 aut | |
700 | 1 | |a Fukumoto, Yoji |e verfasserin |4 aut | |
700 | 1 | |a Shimizu, Shota |e verfasserin |4 aut | |
700 | 1 | |a Kono, Yusuke |e verfasserin |4 aut | |
700 | 1 | |a Murakami, Yuki |e verfasserin |4 aut | |
700 | 1 | |a Shishido, Yuji |e verfasserin |4 aut | |
700 | 1 | |a Miyatani, Kozo |e verfasserin |4 aut | |
700 | 1 | |a Yamamoto, Manabu |e verfasserin |4 aut | |
700 | 1 | |a Tokuyasu, Naruo |e verfasserin |4 aut | |
700 | 1 | |a Takano, Shuichi |e verfasserin |4 aut | |
700 | 1 | |a Sakamoto, Teruhisa |e verfasserin |4 aut | |
700 | 1 | |a Honjo, Soichiro |e verfasserin |4 aut | |
700 | 1 | |a Fujiwara, Yoshiyuki |e verfasserin |4 aut | |
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10.1007/s00595-019-01860-3 doi (DE-627)SPR007039328 (SPR)s00595-019-01860-3-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Matsunaga, Tomoyuki verfasserin aut The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Saito, Hiroaki verfasserin aut Fukumoto, Yoji verfasserin aut Shimizu, Shota verfasserin aut Kono, Yusuke verfasserin aut Murakami, Yuki verfasserin aut Shishido, Yuji verfasserin aut Miyatani, Kozo verfasserin aut Yamamoto, Manabu verfasserin aut Tokuyasu, Naruo verfasserin aut Takano, Shuichi verfasserin aut Sakamoto, Teruhisa verfasserin aut Honjo, Soichiro verfasserin aut Fujiwara, Yoshiyuki verfasserin aut Enthalten in Surgery today Tokyo : Springer, 1971 50(2019), 2 vom: 06. Aug., Seite 123-133 (DE-627)254909604 (DE-600)1463169-6 1436-2813 nnns volume:50 year:2019 number:2 day:06 month:08 pages:123-133 https://dx.doi.org/10.1007/s00595-019-01860-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 50 2019 2 06 08 123-133 |
spelling |
10.1007/s00595-019-01860-3 doi (DE-627)SPR007039328 (SPR)s00595-019-01860-3-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Matsunaga, Tomoyuki verfasserin aut The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Saito, Hiroaki verfasserin aut Fukumoto, Yoji verfasserin aut Shimizu, Shota verfasserin aut Kono, Yusuke verfasserin aut Murakami, Yuki verfasserin aut Shishido, Yuji verfasserin aut Miyatani, Kozo verfasserin aut Yamamoto, Manabu verfasserin aut Tokuyasu, Naruo verfasserin aut Takano, Shuichi verfasserin aut Sakamoto, Teruhisa verfasserin aut Honjo, Soichiro verfasserin aut Fujiwara, Yoshiyuki verfasserin aut Enthalten in Surgery today Tokyo : Springer, 1971 50(2019), 2 vom: 06. Aug., Seite 123-133 (DE-627)254909604 (DE-600)1463169-6 1436-2813 nnns volume:50 year:2019 number:2 day:06 month:08 pages:123-133 https://dx.doi.org/10.1007/s00595-019-01860-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 50 2019 2 06 08 123-133 |
allfields_unstemmed |
10.1007/s00595-019-01860-3 doi (DE-627)SPR007039328 (SPR)s00595-019-01860-3-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Matsunaga, Tomoyuki verfasserin aut The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Saito, Hiroaki verfasserin aut Fukumoto, Yoji verfasserin aut Shimizu, Shota verfasserin aut Kono, Yusuke verfasserin aut Murakami, Yuki verfasserin aut Shishido, Yuji verfasserin aut Miyatani, Kozo verfasserin aut Yamamoto, Manabu verfasserin aut Tokuyasu, Naruo verfasserin aut Takano, Shuichi verfasserin aut Sakamoto, Teruhisa verfasserin aut Honjo, Soichiro verfasserin aut Fujiwara, Yoshiyuki verfasserin aut Enthalten in Surgery today Tokyo : Springer, 1971 50(2019), 2 vom: 06. Aug., Seite 123-133 (DE-627)254909604 (DE-600)1463169-6 1436-2813 nnns volume:50 year:2019 number:2 day:06 month:08 pages:123-133 https://dx.doi.org/10.1007/s00595-019-01860-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 50 2019 2 06 08 123-133 |
allfieldsGer |
10.1007/s00595-019-01860-3 doi (DE-627)SPR007039328 (SPR)s00595-019-01860-3-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Matsunaga, Tomoyuki verfasserin aut The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Saito, Hiroaki verfasserin aut Fukumoto, Yoji verfasserin aut Shimizu, Shota verfasserin aut Kono, Yusuke verfasserin aut Murakami, Yuki verfasserin aut Shishido, Yuji verfasserin aut Miyatani, Kozo verfasserin aut Yamamoto, Manabu verfasserin aut Tokuyasu, Naruo verfasserin aut Takano, Shuichi verfasserin aut Sakamoto, Teruhisa verfasserin aut Honjo, Soichiro verfasserin aut Fujiwara, Yoshiyuki verfasserin aut Enthalten in Surgery today Tokyo : Springer, 1971 50(2019), 2 vom: 06. Aug., Seite 123-133 (DE-627)254909604 (DE-600)1463169-6 1436-2813 nnns volume:50 year:2019 number:2 day:06 month:08 pages:123-133 https://dx.doi.org/10.1007/s00595-019-01860-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 50 2019 2 06 08 123-133 |
allfieldsSound |
10.1007/s00595-019-01860-3 doi (DE-627)SPR007039328 (SPR)s00595-019-01860-3-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Matsunaga, Tomoyuki verfasserin aut The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 Saito, Hiroaki verfasserin aut Fukumoto, Yoji verfasserin aut Shimizu, Shota verfasserin aut Kono, Yusuke verfasserin aut Murakami, Yuki verfasserin aut Shishido, Yuji verfasserin aut Miyatani, Kozo verfasserin aut Yamamoto, Manabu verfasserin aut Tokuyasu, Naruo verfasserin aut Takano, Shuichi verfasserin aut Sakamoto, Teruhisa verfasserin aut Honjo, Soichiro verfasserin aut Fujiwara, Yoshiyuki verfasserin aut Enthalten in Surgery today Tokyo : Springer, 1971 50(2019), 2 vom: 06. Aug., Seite 123-133 (DE-627)254909604 (DE-600)1463169-6 1436-2813 nnns volume:50 year:2019 number:2 day:06 month:08 pages:123-133 https://dx.doi.org/10.1007/s00595-019-01860-3 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 50 2019 2 06 08 123-133 |
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English |
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Enthalten in Surgery today 50(2019), 2 vom: 06. Aug., Seite 123-133 volume:50 year:2019 number:2 day:06 month:08 pages:123-133 |
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Enthalten in Surgery today 50(2019), 2 vom: 06. Aug., Seite 123-133 volume:50 year:2019 number:2 day:06 month:08 pages:123-133 |
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Article |
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topic_facet |
Esophageal cancer Platelet distribution width Prognosis Recurrence |
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Surgery today |
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Matsunaga, Tomoyuki @@aut@@ Saito, Hiroaki @@aut@@ Fukumoto, Yoji @@aut@@ Shimizu, Shota @@aut@@ Kono, Yusuke @@aut@@ Murakami, Yuki @@aut@@ Shishido, Yuji @@aut@@ Miyatani, Kozo @@aut@@ Yamamoto, Manabu @@aut@@ Tokuyasu, Naruo @@aut@@ Takano, Shuichi @@aut@@ Sakamoto, Teruhisa @@aut@@ Honjo, Soichiro @@aut@@ Fujiwara, Yoshiyuki @@aut@@ |
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2019-08-06T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR007039328</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519170149.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201005s2019 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/s00595-019-01860-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR007039328</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s00595-019-01860-3-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.65</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Matsunaga, Tomoyuki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. 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|
author |
Matsunaga, Tomoyuki |
spellingShingle |
Matsunaga, Tomoyuki ddc 610 bkl 44.65 misc Esophageal cancer misc Platelet distribution width misc Prognosis misc Recurrence The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
authorStr |
Matsunaga, Tomoyuki |
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electronic Article |
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610 - Medicine & health |
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Not Illustrated |
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1436-2813 |
topic_title |
610 ASE 44.65 bkl The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma Esophageal cancer (dpeaa)DE-He213 Platelet distribution width (dpeaa)DE-He213 Prognosis (dpeaa)DE-He213 Recurrence (dpeaa)DE-He213 |
topic |
ddc 610 bkl 44.65 misc Esophageal cancer misc Platelet distribution width misc Prognosis misc Recurrence |
topic_unstemmed |
ddc 610 bkl 44.65 misc Esophageal cancer misc Platelet distribution width misc Prognosis misc Recurrence |
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ddc 610 bkl 44.65 misc Esophageal cancer misc Platelet distribution width misc Prognosis misc Recurrence |
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Elektronische Aufsätze Aufsätze Elektronische Ressource |
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Surgery today |
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254909604 |
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610 - Medicine & health |
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The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
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The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
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Matsunaga, Tomoyuki |
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Surgery today |
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Matsunaga, Tomoyuki Saito, Hiroaki Fukumoto, Yoji Shimizu, Shota Kono, Yusuke Murakami, Yuki Shishido, Yuji Miyatani, Kozo Yamamoto, Manabu Tokuyasu, Naruo Takano, Shuichi Sakamoto, Teruhisa Honjo, Soichiro Fujiwara, Yoshiyuki |
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Elektronische Aufsätze |
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Matsunaga, Tomoyuki |
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10.1007/s00595-019-01860-3 |
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postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
title_auth |
The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
abstract |
Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. |
abstractGer |
Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. |
abstract_unstemmed |
Purpose The platelet distribution width (PDW) is reportedly useful as a prognostic indicator for some cancers. However, its prognostic significance in esophageal squamous cell carcinoma (ESCC) is unclear. Methods We enrolled 104 patients with thoracic ESCC, who underwent curative esophagectomy. Results Receiver operating curve analyses indicated that the optimal cut-off values of pre- and postoperative PDW were 16.9 and 17.0, respectively. The 5-year overall survival (OS) rate was significantly lower in patients with a high-preoperative PDW (≥ 16.9; 52.6%) than in those with a low-preoperative PDW (< 16.9; 61.0% P = 0.045). The 5-year disease-specific survival (DSS) rates were 64.3% in patients with a high-preoperative PDW and 69.3% in those with a low-preoperative PDW (P = 0.13). Regarding the postoperative PDW, the 5-year OS rate was significantly lower in patients with a high-postoperative PDW (≥ 17.0; 35.7%) than in those with a low-postoperative PDW (< 17.0; 66.8% P = 0.0017). The 5-year DSS rates were 52.2% in patients with a high-postoperative PDW and 73.2% in those with a low-postoperative PDW (P = 0.037). Finally, a multivariate analysis revealed that the postoperative PDW but not the preoperative PDW was an independent prognostic factor. Conclusions The postoperative PDW was useful for predicting the prognosis of patients with ESCC. |
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The postoperative platelet distribution width is useful for predicting the prognosis in patients with esophageal squamous cell carcinoma |
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Saito, Hiroaki Fukumoto, Yoji Shimizu, Shota Kono, Yusuke Murakami, Yuki Shishido, Yuji Miyatani, Kozo Yamamoto, Manabu Tokuyasu, Naruo Takano, Shuichi Sakamoto, Teruhisa Honjo, Soichiro Fujiwara, Yoshiyuki |
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Saito, Hiroaki Fukumoto, Yoji Shimizu, Shota Kono, Yusuke Murakami, Yuki Shishido, Yuji Miyatani, Kozo Yamamoto, Manabu Tokuyasu, Naruo Takano, Shuichi Sakamoto, Teruhisa Honjo, Soichiro Fujiwara, Yoshiyuki |
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score |
7.401535 |