Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog
Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multipl...
Ausführliche Beschreibung
Autor*in: |
Salgado, Breno S. [verfasserIn] Monteiro, Lidianne N. [verfasserIn] Colodel, Márcia M. [verfasserIn] Figueiroa, Fernanda C. [verfasserIn] Nonogaki, Suely [verfasserIn] Rocha, Rafael M. [verfasserIn] Rocha, Noeme S. [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2012 |
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Übergeordnetes Werk: |
Enthalten in: Comparative haematology international - London : Springer, 1991, 21(2012), 4 vom: 30. Mai, Seite 495-499 |
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Übergeordnetes Werk: |
volume:21 ; year:2012 ; number:4 ; day:30 ; month:05 ; pages:495-499 |
Links: |
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DOI / URN: |
10.1007/s00580-012-1516-4 |
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Katalog-ID: |
SPR007218540 |
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650 | 4 | |a Mammary lobular carcinoma |7 (dpeaa)DE-He213 | |
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700 | 1 | |a Monteiro, Lidianne N. |e verfasserin |4 aut | |
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700 | 1 | |a Nonogaki, Suely |e verfasserin |4 aut | |
700 | 1 | |a Rocha, Rafael M. |e verfasserin |4 aut | |
700 | 1 | |a Rocha, Noeme S. |e verfasserin |4 aut | |
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10.1007/s00580-012-1516-4 doi (DE-627)SPR007218540 (SPR)s00580-012-1516-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE Salgado, Breno S. verfasserin aut Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. Mammary lobular carcinoma (dpeaa)DE-He213 Mammary neoplasms (dpeaa)DE-He213 E-cadherin (dpeaa)DE-He213 Cytokeratin 19 (dpeaa)DE-He213 c-ErbB2 (dpeaa)DE-He213 Oestrogen receptor alpha (dpeaa)DE-He213 Cytodiagnosis (dpeaa)DE-He213 Monteiro, Lidianne N. verfasserin aut Colodel, Márcia M. verfasserin aut Figueiroa, Fernanda C. verfasserin aut Nonogaki, Suely verfasserin aut Rocha, Rafael M. verfasserin aut Rocha, Noeme S. verfasserin aut Enthalten in Comparative haematology international London : Springer, 1991 21(2012), 4 vom: 30. Mai, Seite 495-499 (DE-627)559430590 (DE-600)2413027-8 1433-2973 nnns volume:21 year:2012 number:4 day:30 month:05 pages:495-499 https://dx.doi.org/10.1007/s00580-012-1516-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 21 2012 4 30 05 495-499 |
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10.1007/s00580-012-1516-4 doi (DE-627)SPR007218540 (SPR)s00580-012-1516-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE Salgado, Breno S. verfasserin aut Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. Mammary lobular carcinoma (dpeaa)DE-He213 Mammary neoplasms (dpeaa)DE-He213 E-cadherin (dpeaa)DE-He213 Cytokeratin 19 (dpeaa)DE-He213 c-ErbB2 (dpeaa)DE-He213 Oestrogen receptor alpha (dpeaa)DE-He213 Cytodiagnosis (dpeaa)DE-He213 Monteiro, Lidianne N. verfasserin aut Colodel, Márcia M. verfasserin aut Figueiroa, Fernanda C. verfasserin aut Nonogaki, Suely verfasserin aut Rocha, Rafael M. verfasserin aut Rocha, Noeme S. verfasserin aut Enthalten in Comparative haematology international London : Springer, 1991 21(2012), 4 vom: 30. Mai, Seite 495-499 (DE-627)559430590 (DE-600)2413027-8 1433-2973 nnns volume:21 year:2012 number:4 day:30 month:05 pages:495-499 https://dx.doi.org/10.1007/s00580-012-1516-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 21 2012 4 30 05 495-499 |
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10.1007/s00580-012-1516-4 doi (DE-627)SPR007218540 (SPR)s00580-012-1516-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE Salgado, Breno S. verfasserin aut Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. Mammary lobular carcinoma (dpeaa)DE-He213 Mammary neoplasms (dpeaa)DE-He213 E-cadherin (dpeaa)DE-He213 Cytokeratin 19 (dpeaa)DE-He213 c-ErbB2 (dpeaa)DE-He213 Oestrogen receptor alpha (dpeaa)DE-He213 Cytodiagnosis (dpeaa)DE-He213 Monteiro, Lidianne N. verfasserin aut Colodel, Márcia M. verfasserin aut Figueiroa, Fernanda C. verfasserin aut Nonogaki, Suely verfasserin aut Rocha, Rafael M. verfasserin aut Rocha, Noeme S. verfasserin aut Enthalten in Comparative haematology international London : Springer, 1991 21(2012), 4 vom: 30. Mai, Seite 495-499 (DE-627)559430590 (DE-600)2413027-8 1433-2973 nnns volume:21 year:2012 number:4 day:30 month:05 pages:495-499 https://dx.doi.org/10.1007/s00580-012-1516-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 21 2012 4 30 05 495-499 |
allfieldsGer |
10.1007/s00580-012-1516-4 doi (DE-627)SPR007218540 (SPR)s00580-012-1516-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE Salgado, Breno S. verfasserin aut Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. Mammary lobular carcinoma (dpeaa)DE-He213 Mammary neoplasms (dpeaa)DE-He213 E-cadherin (dpeaa)DE-He213 Cytokeratin 19 (dpeaa)DE-He213 c-ErbB2 (dpeaa)DE-He213 Oestrogen receptor alpha (dpeaa)DE-He213 Cytodiagnosis (dpeaa)DE-He213 Monteiro, Lidianne N. verfasserin aut Colodel, Márcia M. verfasserin aut Figueiroa, Fernanda C. verfasserin aut Nonogaki, Suely verfasserin aut Rocha, Rafael M. verfasserin aut Rocha, Noeme S. verfasserin aut Enthalten in Comparative haematology international London : Springer, 1991 21(2012), 4 vom: 30. Mai, Seite 495-499 (DE-627)559430590 (DE-600)2413027-8 1433-2973 nnns volume:21 year:2012 number:4 day:30 month:05 pages:495-499 https://dx.doi.org/10.1007/s00580-012-1516-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 21 2012 4 30 05 495-499 |
allfieldsSound |
10.1007/s00580-012-1516-4 doi (DE-627)SPR007218540 (SPR)s00580-012-1516-4-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE Salgado, Breno S. verfasserin aut Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. Mammary lobular carcinoma (dpeaa)DE-He213 Mammary neoplasms (dpeaa)DE-He213 E-cadherin (dpeaa)DE-He213 Cytokeratin 19 (dpeaa)DE-He213 c-ErbB2 (dpeaa)DE-He213 Oestrogen receptor alpha (dpeaa)DE-He213 Cytodiagnosis (dpeaa)DE-He213 Monteiro, Lidianne N. verfasserin aut Colodel, Márcia M. verfasserin aut Figueiroa, Fernanda C. verfasserin aut Nonogaki, Suely verfasserin aut Rocha, Rafael M. verfasserin aut Rocha, Noeme S. verfasserin aut Enthalten in Comparative haematology international London : Springer, 1991 21(2012), 4 vom: 30. Mai, Seite 495-499 (DE-627)559430590 (DE-600)2413027-8 1433-2973 nnns volume:21 year:2012 number:4 day:30 month:05 pages:495-499 https://dx.doi.org/10.1007/s00580-012-1516-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_120 GBV_ILN_152 GBV_ILN_161 GBV_ILN_171 GBV_ILN_187 GBV_ILN_224 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 AR 21 2012 4 30 05 495-499 |
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Enthalten in Comparative haematology international 21(2012), 4 vom: 30. Mai, Seite 495-499 volume:21 year:2012 number:4 day:30 month:05 pages:495-499 |
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Salgado, Breno S. @@aut@@ Monteiro, Lidianne N. @@aut@@ Colodel, Márcia M. @@aut@@ Figueiroa, Fernanda C. @@aut@@ Nonogaki, Suely @@aut@@ Rocha, Rafael M. @@aut@@ Rocha, Noeme S. @@aut@@ |
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cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog |
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Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog |
abstract |
Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. |
abstractGer |
Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. |
abstract_unstemmed |
Abstract This case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. |
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Cytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog |
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