Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium
Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovin...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Weber, Helmut P. [verfasserIn] Sagerer-Gerhardt, Michaela [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Lasers in medical science - London : Springer, 1986, 29(2013), 3 vom: 11. Dez., Seite 1183-1187 |
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| Übergeordnetes Werk: |
volume:29 ; year:2013 ; number:3 ; day:11 ; month:12 ; pages:1183-1187 |
| Links: |
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| DOI / URN: |
10.1007/s10103-013-1505-0 |
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| Katalog-ID: |
SPR008757178 |
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| 245 | 1 | 0 | |a Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
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| 520 | |a Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. | ||
| 650 | 4 | |a Catheter ablation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Laser ablation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Catheter irrigation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Noncontact laser application |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Contact pressure |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Sagerer-Gerhardt, Michaela |e verfasserin |4 aut | |
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10.1007/s10103-013-1505-0 doi (DE-627)SPR008757178 (SPR)s10103-013-1505-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Weber, Helmut P. verfasserin aut Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 Sagerer-Gerhardt, Michaela verfasserin aut Enthalten in Lasers in medical science London : Springer, 1986 29(2013), 3 vom: 11. Dez., Seite 1183-1187 (DE-627)300186223 (DE-600)1481688-X 1435-604X nnns volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 https://dx.doi.org/10.1007/s10103-013-1505-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 29 2013 3 11 12 1183-1187 |
| spelling |
10.1007/s10103-013-1505-0 doi (DE-627)SPR008757178 (SPR)s10103-013-1505-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Weber, Helmut P. verfasserin aut Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 Sagerer-Gerhardt, Michaela verfasserin aut Enthalten in Lasers in medical science London : Springer, 1986 29(2013), 3 vom: 11. Dez., Seite 1183-1187 (DE-627)300186223 (DE-600)1481688-X 1435-604X nnns volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 https://dx.doi.org/10.1007/s10103-013-1505-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 29 2013 3 11 12 1183-1187 |
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10.1007/s10103-013-1505-0 doi (DE-627)SPR008757178 (SPR)s10103-013-1505-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Weber, Helmut P. verfasserin aut Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 Sagerer-Gerhardt, Michaela verfasserin aut Enthalten in Lasers in medical science London : Springer, 1986 29(2013), 3 vom: 11. Dez., Seite 1183-1187 (DE-627)300186223 (DE-600)1481688-X 1435-604X nnns volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 https://dx.doi.org/10.1007/s10103-013-1505-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 29 2013 3 11 12 1183-1187 |
| allfieldsGer |
10.1007/s10103-013-1505-0 doi (DE-627)SPR008757178 (SPR)s10103-013-1505-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Weber, Helmut P. verfasserin aut Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 Sagerer-Gerhardt, Michaela verfasserin aut Enthalten in Lasers in medical science London : Springer, 1986 29(2013), 3 vom: 11. Dez., Seite 1183-1187 (DE-627)300186223 (DE-600)1481688-X 1435-604X nnns volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 https://dx.doi.org/10.1007/s10103-013-1505-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 29 2013 3 11 12 1183-1187 |
| allfieldsSound |
10.1007/s10103-013-1505-0 doi (DE-627)SPR008757178 (SPR)s10103-013-1505-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.65 bkl Weber, Helmut P. verfasserin aut Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 Sagerer-Gerhardt, Michaela verfasserin aut Enthalten in Lasers in medical science London : Springer, 1986 29(2013), 3 vom: 11. Dez., Seite 1183-1187 (DE-627)300186223 (DE-600)1481688-X 1435-604X nnns volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 https://dx.doi.org/10.1007/s10103-013-1505-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.65 ASE AR 29 2013 3 11 12 1183-1187 |
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English |
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Enthalten in Lasers in medical science 29(2013), 3 vom: 11. Dez., Seite 1183-1187 volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 |
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Enthalten in Lasers in medical science 29(2013), 3 vom: 11. Dez., Seite 1183-1187 volume:29 year:2013 number:3 day:11 month:12 pages:1183-1187 |
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Catheter ablation Laser ablation Catheter irrigation Noncontact laser application Contact pressure |
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Lasers in medical science |
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Weber, Helmut P. @@aut@@ Sagerer-Gerhardt, Michaela @@aut@@ |
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2013-12-11T00:00:00Z |
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Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. 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Weber, Helmut P. |
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Weber, Helmut P. ddc 610 bkl 44.65 misc Catheter ablation misc Laser ablation misc Catheter irrigation misc Noncontact laser application misc Contact pressure Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
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610 ASE 44.65 bkl Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium Catheter ablation (dpeaa)DE-He213 Laser ablation (dpeaa)DE-He213 Catheter irrigation (dpeaa)DE-He213 Noncontact laser application (dpeaa)DE-He213 Contact pressure (dpeaa)DE-He213 |
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ddc 610 bkl 44.65 misc Catheter ablation misc Laser ablation misc Catheter irrigation misc Noncontact laser application misc Contact pressure |
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ddc 610 bkl 44.65 misc Catheter ablation misc Laser ablation misc Catheter irrigation misc Noncontact laser application misc Contact pressure |
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ddc 610 bkl 44.65 misc Catheter ablation misc Laser ablation misc Catheter irrigation misc Noncontact laser application misc Contact pressure |
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Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
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(DE-627)SPR008757178 (SPR)s10103-013-1505-0-e |
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Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
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Weber, Helmut P. |
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Lasers in medical science |
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Weber, Helmut P. Sagerer-Gerhardt, Michaela |
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610 ASE 44.65 bkl |
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Weber, Helmut P. |
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verfasserin |
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open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
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Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
| abstract |
Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. |
| abstractGer |
Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. |
| abstract_unstemmed |
Abstract Lesions achieved by radiofrequency application increase with catheter irrigation and with catheter pressure on the endocardial surface. Purpose of this study was to test the influence of catheter irrigation and of contact vs. noncontact mode of laser application on lesion formation in bovine myocardium. By applying continuous wave 1,064 nm laser light via an open-irrigated catheter lesions were produced at 15 W (9.5 W/$ mm^{2} $)/30 s (285 J/$ mm^{2} $), in stagnant blood (activated clotting time > 350 s) at 18 °C, on bovine myocardium. During flow rates of 15, 30, and 50 ml/min radiation was applied with the catheter end hole in contact (n = 10, each) or 2 mm away from the endocardial surface (n = 5, each). Lesions were evaluated morphometrically, and groups of lesions were compared by using the unpaired t test. By augmentation of irrigation flow from 15 to 30 ml/min, contact lesions increased significantly (p = 0.0001). A further increase of flow from 30 to 50 ml/min increased lesions significantly in depth (p = 0.0011) but not in width (p = 0.639) and volume (p = 0.218). Noncontact lesions were significantly smaller than contact lesions (p > 0.05). Lesions of homogenous coagulation necrosis were clear-cut and sharply demarcated from the surrounding normal myocardium. There was no occurrence of steam-pop with intramural cavitation or with tissue vaporization with crater or thrombus formation. It is suggested that by using an open-irrigated laser catheter as described in this study, catheter irrigation at flow rates of 30 to 40 ml/min are optimal for myocardial coagulation, and catheter pressure on the endocardial surface is not needed for lesion formation. Laser lesions can be achieved also without intimate endocardial catheter contact. |
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| container_issue |
3 |
| title_short |
Open-irrigated laser catheter ablation: influence of catheter irrigation and of contact and noncontact mode of laser application on lesion formation in bovine myocardium |
| url |
https://dx.doi.org/10.1007/s10103-013-1505-0 |
| remote_bool |
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| author2 |
Sagerer-Gerhardt, Michaela |
| author2Str |
Sagerer-Gerhardt, Michaela |
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| doi_str |
10.1007/s10103-013-1505-0 |
| up_date |
2024-07-03T22:59:23.598Z |
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| score |
7.3985147 |