Dipstick proteinuria and all-cause mortality among the general population
Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance p...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Iseki, Kunitoshi [verfasserIn] Konta, Tsuneo [verfasserIn] Asahi, Koichi [verfasserIn] Yamagata, Kunihiro [verfasserIn] Fujimoto, Shouichi [verfasserIn] Tsuruya, Kazuhiko [verfasserIn] Narita, Ichiei [verfasserIn] Kasahara, Masato [verfasserIn] Shibagaki, Yugo [verfasserIn] Moriyama, Toshiki [verfasserIn] Kondo, Masahide [verfasserIn] Iseki, Chiho [verfasserIn] Watanabe, Tsuyoshi [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Clinical and experimental nephrology - [Tokyo] : Springer, 1997, 22(2018), 6 vom: 05. Juni, Seite 1331-1340 |
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| Übergeordnetes Werk: |
volume:22 ; year:2018 ; number:6 ; day:05 ; month:06 ; pages:1331-1340 |
| Links: |
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| DOI / URN: |
10.1007/s10157-018-1587-x |
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| Katalog-ID: |
SPR008979502 |
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| 245 | 1 | 0 | |a Dipstick proteinuria and all-cause mortality among the general population |
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| 520 | |a Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. | ||
| 650 | 4 | |a Dipstick proteinuria |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Screening |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Mortality |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cardiovascular disease |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Konta, Tsuneo |e verfasserin |4 aut | |
| 700 | 1 | |a Asahi, Koichi |e verfasserin |4 aut | |
| 700 | 1 | |a Yamagata, Kunihiro |e verfasserin |4 aut | |
| 700 | 1 | |a Fujimoto, Shouichi |e verfasserin |4 aut | |
| 700 | 1 | |a Tsuruya, Kazuhiko |e verfasserin |4 aut | |
| 700 | 1 | |a Narita, Ichiei |e verfasserin |4 aut | |
| 700 | 1 | |a Kasahara, Masato |e verfasserin |4 aut | |
| 700 | 1 | |a Shibagaki, Yugo |e verfasserin |4 aut | |
| 700 | 1 | |a Moriyama, Toshiki |e verfasserin |4 aut | |
| 700 | 1 | |a Kondo, Masahide |e verfasserin |4 aut | |
| 700 | 1 | |a Iseki, Chiho |e verfasserin |4 aut | |
| 700 | 1 | |a Watanabe, Tsuyoshi |e verfasserin |4 aut | |
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10.1007/s10157-018-1587-x doi (DE-627)SPR008979502 (SPR)s10157-018-1587-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.88 bkl Iseki, Kunitoshi verfasserin aut Dipstick proteinuria and all-cause mortality among the general population 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 Konta, Tsuneo verfasserin aut Asahi, Koichi verfasserin aut Yamagata, Kunihiro verfasserin aut Fujimoto, Shouichi verfasserin aut Tsuruya, Kazuhiko verfasserin aut Narita, Ichiei verfasserin aut Kasahara, Masato verfasserin aut Shibagaki, Yugo verfasserin aut Moriyama, Toshiki verfasserin aut Kondo, Masahide verfasserin aut Iseki, Chiho verfasserin aut Watanabe, Tsuyoshi verfasserin aut Enthalten in Clinical and experimental nephrology [Tokyo] : Springer, 1997 22(2018), 6 vom: 05. Juni, Seite 1331-1340 (DE-627)306646900 (DE-600)1499111-1 1437-7799 nnns volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 https://dx.doi.org/10.1007/s10157-018-1587-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.88 ASE AR 22 2018 6 05 06 1331-1340 |
| spelling |
10.1007/s10157-018-1587-x doi (DE-627)SPR008979502 (SPR)s10157-018-1587-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.88 bkl Iseki, Kunitoshi verfasserin aut Dipstick proteinuria and all-cause mortality among the general population 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 Konta, Tsuneo verfasserin aut Asahi, Koichi verfasserin aut Yamagata, Kunihiro verfasserin aut Fujimoto, Shouichi verfasserin aut Tsuruya, Kazuhiko verfasserin aut Narita, Ichiei verfasserin aut Kasahara, Masato verfasserin aut Shibagaki, Yugo verfasserin aut Moriyama, Toshiki verfasserin aut Kondo, Masahide verfasserin aut Iseki, Chiho verfasserin aut Watanabe, Tsuyoshi verfasserin aut Enthalten in Clinical and experimental nephrology [Tokyo] : Springer, 1997 22(2018), 6 vom: 05. Juni, Seite 1331-1340 (DE-627)306646900 (DE-600)1499111-1 1437-7799 nnns volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 https://dx.doi.org/10.1007/s10157-018-1587-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.88 ASE AR 22 2018 6 05 06 1331-1340 |
| allfields_unstemmed |
10.1007/s10157-018-1587-x doi (DE-627)SPR008979502 (SPR)s10157-018-1587-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.88 bkl Iseki, Kunitoshi verfasserin aut Dipstick proteinuria and all-cause mortality among the general population 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 Konta, Tsuneo verfasserin aut Asahi, Koichi verfasserin aut Yamagata, Kunihiro verfasserin aut Fujimoto, Shouichi verfasserin aut Tsuruya, Kazuhiko verfasserin aut Narita, Ichiei verfasserin aut Kasahara, Masato verfasserin aut Shibagaki, Yugo verfasserin aut Moriyama, Toshiki verfasserin aut Kondo, Masahide verfasserin aut Iseki, Chiho verfasserin aut Watanabe, Tsuyoshi verfasserin aut Enthalten in Clinical and experimental nephrology [Tokyo] : Springer, 1997 22(2018), 6 vom: 05. Juni, Seite 1331-1340 (DE-627)306646900 (DE-600)1499111-1 1437-7799 nnns volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 https://dx.doi.org/10.1007/s10157-018-1587-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.88 ASE AR 22 2018 6 05 06 1331-1340 |
| allfieldsGer |
10.1007/s10157-018-1587-x doi (DE-627)SPR008979502 (SPR)s10157-018-1587-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.88 bkl Iseki, Kunitoshi verfasserin aut Dipstick proteinuria and all-cause mortality among the general population 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 Konta, Tsuneo verfasserin aut Asahi, Koichi verfasserin aut Yamagata, Kunihiro verfasserin aut Fujimoto, Shouichi verfasserin aut Tsuruya, Kazuhiko verfasserin aut Narita, Ichiei verfasserin aut Kasahara, Masato verfasserin aut Shibagaki, Yugo verfasserin aut Moriyama, Toshiki verfasserin aut Kondo, Masahide verfasserin aut Iseki, Chiho verfasserin aut Watanabe, Tsuyoshi verfasserin aut Enthalten in Clinical and experimental nephrology [Tokyo] : Springer, 1997 22(2018), 6 vom: 05. Juni, Seite 1331-1340 (DE-627)306646900 (DE-600)1499111-1 1437-7799 nnns volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 https://dx.doi.org/10.1007/s10157-018-1587-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.88 ASE AR 22 2018 6 05 06 1331-1340 |
| allfieldsSound |
10.1007/s10157-018-1587-x doi (DE-627)SPR008979502 (SPR)s10157-018-1587-x-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.88 bkl Iseki, Kunitoshi verfasserin aut Dipstick proteinuria and all-cause mortality among the general population 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 Konta, Tsuneo verfasserin aut Asahi, Koichi verfasserin aut Yamagata, Kunihiro verfasserin aut Fujimoto, Shouichi verfasserin aut Tsuruya, Kazuhiko verfasserin aut Narita, Ichiei verfasserin aut Kasahara, Masato verfasserin aut Shibagaki, Yugo verfasserin aut Moriyama, Toshiki verfasserin aut Kondo, Masahide verfasserin aut Iseki, Chiho verfasserin aut Watanabe, Tsuyoshi verfasserin aut Enthalten in Clinical and experimental nephrology [Tokyo] : Springer, 1997 22(2018), 6 vom: 05. Juni, Seite 1331-1340 (DE-627)306646900 (DE-600)1499111-1 1437-7799 nnns volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 https://dx.doi.org/10.1007/s10157-018-1587-x lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.88 ASE AR 22 2018 6 05 06 1331-1340 |
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Enthalten in Clinical and experimental nephrology 22(2018), 6 vom: 05. Juni, Seite 1331-1340 volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 |
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Enthalten in Clinical and experimental nephrology 22(2018), 6 vom: 05. Juni, Seite 1331-1340 volume:22 year:2018 number:6 day:05 month:06 pages:1331-1340 |
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Dipstick proteinuria Screening Mortality Cancer Cardiovascular disease |
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Clinical and experimental nephrology |
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Iseki, Kunitoshi @@aut@@ Konta, Tsuneo @@aut@@ Asahi, Koichi @@aut@@ Yamagata, Kunihiro @@aut@@ Fujimoto, Shouichi @@aut@@ Tsuruya, Kazuhiko @@aut@@ Narita, Ichiei @@aut@@ Kasahara, Masato @@aut@@ Shibagaki, Yugo @@aut@@ Moriyama, Toshiki @@aut@@ Kondo, Masahide @@aut@@ Iseki, Chiho @@aut@@ Watanabe, Tsuyoshi @@aut@@ |
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2018-06-05T00:00:00Z |
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How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). 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| author |
Iseki, Kunitoshi |
| spellingShingle |
Iseki, Kunitoshi ddc 610 bkl 44.88 misc Dipstick proteinuria misc Screening misc Mortality misc Cancer misc Cardiovascular disease Dipstick proteinuria and all-cause mortality among the general population |
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1437-7799 |
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610 ASE 44.88 bkl Dipstick proteinuria and all-cause mortality among the general population Dipstick proteinuria (dpeaa)DE-He213 Screening (dpeaa)DE-He213 Mortality (dpeaa)DE-He213 Cancer (dpeaa)DE-He213 Cardiovascular disease (dpeaa)DE-He213 |
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ddc 610 bkl 44.88 misc Dipstick proteinuria misc Screening misc Mortality misc Cancer misc Cardiovascular disease |
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ddc 610 bkl 44.88 misc Dipstick proteinuria misc Screening misc Mortality misc Cancer misc Cardiovascular disease |
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ddc 610 bkl 44.88 misc Dipstick proteinuria misc Screening misc Mortality misc Cancer misc Cardiovascular disease |
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Clinical and experimental nephrology |
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Clinical and experimental nephrology |
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Dipstick proteinuria and all-cause mortality among the general population |
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(DE-627)SPR008979502 (SPR)s10157-018-1587-x-e |
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Dipstick proteinuria and all-cause mortality among the general population |
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Iseki, Kunitoshi |
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Clinical and experimental nephrology |
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Clinical and experimental nephrology |
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eng |
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Iseki, Kunitoshi Konta, Tsuneo Asahi, Koichi Yamagata, Kunihiro Fujimoto, Shouichi Tsuruya, Kazuhiko Narita, Ichiei Kasahara, Masato Shibagaki, Yugo Moriyama, Toshiki Kondo, Masahide Iseki, Chiho Watanabe, Tsuyoshi |
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Iseki, Kunitoshi |
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10.1007/s10157-018-1587-x |
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610 |
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verfasserin |
| title_sort |
dipstick proteinuria and all-cause mortality among the general population |
| title_auth |
Dipstick proteinuria and all-cause mortality among the general population |
| abstract |
Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. |
| abstractGer |
Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. |
| abstract_unstemmed |
Background Dipstick proteinuria, but not albuminuria, is used for general health screening in Japan. How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). Conclusion Dipstick proteinuria is an independent predictor of death among Japanese community-based screening participants. |
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Dipstick proteinuria and all-cause mortality among the general population |
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https://dx.doi.org/10.1007/s10157-018-1587-x |
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Konta, Tsuneo Asahi, Koichi Yamagata, Kunihiro Fujimoto, Shouichi Tsuruya, Kazuhiko Narita, Ichiei Kasahara, Masato Shibagaki, Yugo Moriyama, Toshiki Kondo, Masahide Iseki, Chiho Watanabe, Tsuyoshi |
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Konta, Tsuneo Asahi, Koichi Yamagata, Kunihiro Fujimoto, Shouichi Tsuruya, Kazuhiko Narita, Ichiei Kasahara, Masato Shibagaki, Yugo Moriyama, Toshiki Kondo, Masahide Iseki, Chiho Watanabe, Tsuyoshi |
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10.1007/s10157-018-1587-x |
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2024-07-04T00:09:34.706Z |
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How the results of dipstick proteinuria tests correlate with mortality and, however, is not known. Methods Subjects were participants of the 2008 Tokutei-Kenshin (Specific Health Check and Guidance program) in six districts in Japan. On the basis of the national database of death certificates from 2008 to 2012, we used a personal identifier in two computer registries to identify participants who might have died. The hazard ratio (95% confidence interval, CI) was calculated by Cox-proportional hazard analysis. Results Among a total of 140,761 subjects, we identified 1641 mortalities that occurred by the end of 2012. The crude mortality rates were 1.1% for subjects who were proteinuria (−), 1.5% for those with proteinuria (+/−), 2.0% for those with proteinuria (1+), 3.5% for those with proteinuria (2+), and 3.7% for those with proteinuria (≥ 3+). After adjusting for sex, age, body mass index, estimated glomerular filtration rate, comorbid condition, past history, and lifestyle, the hazard ratio (95% CI) for dipstick proteinuria was 1.262 (1.079–1.467) for those with proteinuria (+/−), 1.437 (1.168–1.748) for those with proteinuria (1+), 2.201 (1.688–2.867) for those with proteinuria (2+), and 2.222 (1.418–3.301) for those with proteinuria (≥ 3+) compared with the reference of proteinuria (−). 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