Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis

Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by...
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Gespeichert in:

Autor*in:	Shibuya, Mihoko [verfasserIn] Fujio, Keishi [verfasserIn] Morita, Kaoru [verfasserIn] Harada, Hiroaki [verfasserIn] Kanda, Hiroko [verfasserIn] Yamamoto, Kazuhiko [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Cogan’s syndrome Aortitis Tocilizumab IL-6

Übergeordnetes Werk:	Enthalten in: Modern rheumatology - Oxford : Oxford University Press, 2000, 23(2012), 3 vom: 01. Juli, Seite 577-581
Übergeordnetes Werk:	volume:23 ; year:2012 ; number:3 ; day:01 ; month:07 ; pages:577-581

Links:	Volltext

DOI / URN:	10.1007/s10165-012-0691-0

Katalog-ID:	SPR00902770X

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allfields	10.1007/s10165-012-0691-0 doi (DE-627)SPR00902770X (SPR)s10165-012-0691-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.83 bkl Shibuya, Mihoko verfasserin aut Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody. Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213 Fujio, Keishi verfasserin aut Morita, Kaoru verfasserin aut Harada, Hiroaki verfasserin aut Kanda, Hiroko verfasserin aut Yamamoto, Kazuhiko verfasserin aut Enthalten in Modern rheumatology Oxford : Oxford University Press, 2000 23(2012), 3 vom: 01. Juli, Seite 577-581 (DE-627)320627497 (DE-600)2023498-3 1439-7609 nnns volume:23 year:2012 number:3 day:01 month:07 pages:577-581 https://dx.doi.org/10.1007/s10165-012-0691-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_151 GBV_ILN_170 GBV_ILN_224 GBV_ILN_267 GBV_ILN_285 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2026 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4328 GBV_ILN_4333 44.83 ASE AR 23 2012 3 01 07 577-581
spelling	10.1007/s10165-012-0691-0 doi (DE-627)SPR00902770X (SPR)s10165-012-0691-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.83 bkl Shibuya, Mihoko verfasserin aut Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody. Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213 Fujio, Keishi verfasserin aut Morita, Kaoru verfasserin aut Harada, Hiroaki verfasserin aut Kanda, Hiroko verfasserin aut Yamamoto, Kazuhiko verfasserin aut Enthalten in Modern rheumatology Oxford : Oxford University Press, 2000 23(2012), 3 vom: 01. Juli, Seite 577-581 (DE-627)320627497 (DE-600)2023498-3 1439-7609 nnns volume:23 year:2012 number:3 day:01 month:07 pages:577-581 https://dx.doi.org/10.1007/s10165-012-0691-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_151 GBV_ILN_170 GBV_ILN_224 GBV_ILN_267 GBV_ILN_285 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2026 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4328 GBV_ILN_4333 44.83 ASE AR 23 2012 3 01 07 577-581
allfields_unstemmed	10.1007/s10165-012-0691-0 doi (DE-627)SPR00902770X (SPR)s10165-012-0691-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.83 bkl Shibuya, Mihoko verfasserin aut Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody. Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213 Fujio, Keishi verfasserin aut Morita, Kaoru verfasserin aut Harada, Hiroaki verfasserin aut Kanda, Hiroko verfasserin aut Yamamoto, Kazuhiko verfasserin aut Enthalten in Modern rheumatology Oxford : Oxford University Press, 2000 23(2012), 3 vom: 01. Juli, Seite 577-581 (DE-627)320627497 (DE-600)2023498-3 1439-7609 nnns volume:23 year:2012 number:3 day:01 month:07 pages:577-581 https://dx.doi.org/10.1007/s10165-012-0691-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_151 GBV_ILN_170 GBV_ILN_224 GBV_ILN_267 GBV_ILN_285 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2026 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4328 GBV_ILN_4333 44.83 ASE AR 23 2012 3 01 07 577-581
allfieldsGer	10.1007/s10165-012-0691-0 doi (DE-627)SPR00902770X (SPR)s10165-012-0691-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.83 bkl Shibuya, Mihoko verfasserin aut Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody. Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213 Fujio, Keishi verfasserin aut Morita, Kaoru verfasserin aut Harada, Hiroaki verfasserin aut Kanda, Hiroko verfasserin aut Yamamoto, Kazuhiko verfasserin aut Enthalten in Modern rheumatology Oxford : Oxford University Press, 2000 23(2012), 3 vom: 01. Juli, Seite 577-581 (DE-627)320627497 (DE-600)2023498-3 1439-7609 nnns volume:23 year:2012 number:3 day:01 month:07 pages:577-581 https://dx.doi.org/10.1007/s10165-012-0691-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_151 GBV_ILN_170 GBV_ILN_224 GBV_ILN_267 GBV_ILN_285 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2026 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4328 GBV_ILN_4333 44.83 ASE AR 23 2012 3 01 07 577-581
allfieldsSound	10.1007/s10165-012-0691-0 doi (DE-627)SPR00902770X (SPR)s10165-012-0691-0-e DE-627 ger DE-627 rakwb eng 610 ASE 610 ASE 44.83 bkl Shibuya, Mihoko verfasserin aut Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody. Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213 Fujio, Keishi verfasserin aut Morita, Kaoru verfasserin aut Harada, Hiroaki verfasserin aut Kanda, Hiroko verfasserin aut Yamamoto, Kazuhiko verfasserin aut Enthalten in Modern rheumatology Oxford : Oxford University Press, 2000 23(2012), 3 vom: 01. Juli, Seite 577-581 (DE-627)320627497 (DE-600)2023498-3 1439-7609 nnns volume:23 year:2012 number:3 day:01 month:07 pages:577-581 https://dx.doi.org/10.1007/s10165-012-0691-0 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_20 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_151 GBV_ILN_170 GBV_ILN_224 GBV_ILN_267 GBV_ILN_285 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2026 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4328 GBV_ILN_4333 44.83 ASE AR 23 2012 3 01 07 577-581
language	English
source	Enthalten in Modern rheumatology 23(2012), 3 vom: 01. Juli, Seite 577-581 volume:23 year:2012 number:3 day:01 month:07 pages:577-581
sourceStr	Enthalten in Modern rheumatology 23(2012), 3 vom: 01. Juli, Seite 577-581 volume:23 year:2012 number:3 day:01 month:07 pages:577-581
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Cogan’s syndrome Aortitis Tocilizumab IL-6
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container_title	Modern rheumatology
authorswithroles_txt_mv	Shibuya, Mihoko @@aut@@ Fujio, Keishi @@aut@@ Morita, Kaoru @@aut@@ Harada, Hiroaki @@aut@@ Kanda, Hiroko @@aut@@ Yamamoto, Kazuhiko @@aut@@
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author	Shibuya, Mihoko
spellingShingle	Shibuya, Mihoko ddc 610 bkl 44.83 misc Cogan’s syndrome misc Aortitis misc Tocilizumab misc IL-6 Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
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topic_title	610 ASE 44.83 bkl Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis Cogan’s syndrome (dpeaa)DE-He213 Aortitis (dpeaa)DE-He213 Tocilizumab (dpeaa)DE-He213 IL-6 (dpeaa)DE-He213
topic	ddc 610 bkl 44.83 misc Cogan’s syndrome misc Aortitis misc Tocilizumab misc IL-6
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title	Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
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title_full	Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
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author_browse	Shibuya, Mihoko Fujio, Keishi Morita, Kaoru Harada, Hiroaki Kanda, Hiroko Yamamoto, Kazuhiko
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title_sort	successful treatment with tocilizumab in a case of cogan’s syndrome complicated with aortitis
title_auth	Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
abstract	Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody.
abstractGer	Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody.
abstract_unstemmed	Abstract A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody.
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container_issue	3
title_short	Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
url	https://dx.doi.org/10.1007/s10165-012-0691-0
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author2	Fujio, Keishi Morita, Kaoru Harada, Hiroaki Kanda, Hiroko Yamamoto, Kazuhiko
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up_date	2024-07-04T00:22:42.825Z
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