Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation
Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromat...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zhu, Xiaoyan [verfasserIn] Meng, Zhiqiang [verfasserIn] Chen, Zhen [verfasserIn] Liu, Luming [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2009 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Chromatographia - Wiesbaden : Vieweg, 1968, 69(2009), 7-8 vom: 04. Feb., Seite 749-754 |
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| Übergeordnetes Werk: |
volume:69 ; year:2009 ; number:7-8 ; day:04 ; month:02 ; pages:749-754 |
| Links: |
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| DOI / URN: |
10.1365/s10337-009-0973-7 |
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| Katalog-ID: |
SPR009543082 |
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| 245 | 1 | 0 | |a Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
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| 520 | |a Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. | ||
| 650 | 4 | |a Gas chromatography–mass spectrometry |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Microwave-assisted silylation |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Resibufogenin and cinobufagin |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Ch’an Su |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Meng, Zhiqiang |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Zhen |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Luming |e verfasserin |4 aut | |
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10.1365/s10337-009-0973-7 doi (DE-627)SPR009543082 (SPR)s10337-009-0973-7-e DE-627 ger DE-627 rakwb eng 540 ASE 540 ASE 35.29 bkl Zhu, Xiaoyan verfasserin aut Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 Meng, Zhiqiang verfasserin aut Chen, Zhen verfasserin aut Liu, Luming verfasserin aut Enthalten in Chromatographia Wiesbaden : Vieweg, 1968 69(2009), 7-8 vom: 04. Feb., Seite 749-754 (DE-627)320592219 (DE-600)2019091-8 1612-1112 nnns volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 https://dx.doi.org/10.1365/s10337-009-0973-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.29 ASE AR 69 2009 7-8 04 02 749-754 |
| spelling |
10.1365/s10337-009-0973-7 doi (DE-627)SPR009543082 (SPR)s10337-009-0973-7-e DE-627 ger DE-627 rakwb eng 540 ASE 540 ASE 35.29 bkl Zhu, Xiaoyan verfasserin aut Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 Meng, Zhiqiang verfasserin aut Chen, Zhen verfasserin aut Liu, Luming verfasserin aut Enthalten in Chromatographia Wiesbaden : Vieweg, 1968 69(2009), 7-8 vom: 04. Feb., Seite 749-754 (DE-627)320592219 (DE-600)2019091-8 1612-1112 nnns volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 https://dx.doi.org/10.1365/s10337-009-0973-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.29 ASE AR 69 2009 7-8 04 02 749-754 |
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10.1365/s10337-009-0973-7 doi (DE-627)SPR009543082 (SPR)s10337-009-0973-7-e DE-627 ger DE-627 rakwb eng 540 ASE 540 ASE 35.29 bkl Zhu, Xiaoyan verfasserin aut Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 Meng, Zhiqiang verfasserin aut Chen, Zhen verfasserin aut Liu, Luming verfasserin aut Enthalten in Chromatographia Wiesbaden : Vieweg, 1968 69(2009), 7-8 vom: 04. Feb., Seite 749-754 (DE-627)320592219 (DE-600)2019091-8 1612-1112 nnns volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 https://dx.doi.org/10.1365/s10337-009-0973-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.29 ASE AR 69 2009 7-8 04 02 749-754 |
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10.1365/s10337-009-0973-7 doi (DE-627)SPR009543082 (SPR)s10337-009-0973-7-e DE-627 ger DE-627 rakwb eng 540 ASE 540 ASE 35.29 bkl Zhu, Xiaoyan verfasserin aut Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 Meng, Zhiqiang verfasserin aut Chen, Zhen verfasserin aut Liu, Luming verfasserin aut Enthalten in Chromatographia Wiesbaden : Vieweg, 1968 69(2009), 7-8 vom: 04. Feb., Seite 749-754 (DE-627)320592219 (DE-600)2019091-8 1612-1112 nnns volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 https://dx.doi.org/10.1365/s10337-009-0973-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.29 ASE AR 69 2009 7-8 04 02 749-754 |
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10.1365/s10337-009-0973-7 doi (DE-627)SPR009543082 (SPR)s10337-009-0973-7-e DE-627 ger DE-627 rakwb eng 540 ASE 540 ASE 35.29 bkl Zhu, Xiaoyan verfasserin aut Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 Meng, Zhiqiang verfasserin aut Chen, Zhen verfasserin aut Liu, Luming verfasserin aut Enthalten in Chromatographia Wiesbaden : Vieweg, 1968 69(2009), 7-8 vom: 04. Feb., Seite 749-754 (DE-627)320592219 (DE-600)2019091-8 1612-1112 nnns volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 https://dx.doi.org/10.1365/s10337-009-0973-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_267 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.29 ASE AR 69 2009 7-8 04 02 749-754 |
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Enthalten in Chromatographia 69(2009), 7-8 vom: 04. Feb., Seite 749-754 volume:69 year:2009 number:7-8 day:04 month:02 pages:749-754 |
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Gas chromatography–mass spectrometry Microwave-assisted silylation Resibufogenin and cinobufagin Ch’an Su |
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Zhu, Xiaoyan @@aut@@ Meng, Zhiqiang @@aut@@ Chen, Zhen @@aut@@ Liu, Luming @@aut@@ |
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2009-02-04T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR009543082</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519173608.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201005s2009 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1365/s10337-009-0973-7</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR009543082</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s10337-009-0973-7-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">540</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">35.29</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zhu, Xiaoyan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2009</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gas chromatography–mass spectrometry</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microwave-assisted silylation</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Resibufogenin and cinobufagin</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ch’an Su</subfield><subfield code="7">(dpeaa)DE-He213</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Meng, Zhiqiang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chen, Zhen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Liu, Luming</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Chromatographia</subfield><subfield code="d">Wiesbaden : Vieweg, 1968</subfield><subfield code="g">69(2009), 7-8 vom: 04. 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Zhu, Xiaoyan |
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Zhu, Xiaoyan ddc 540 bkl 35.29 misc Gas chromatography–mass spectrometry misc Microwave-assisted silylation misc Resibufogenin and cinobufagin misc Ch’an Su Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
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540 ASE 35.29 bkl Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation Gas chromatography–mass spectrometry (dpeaa)DE-He213 Microwave-assisted silylation (dpeaa)DE-He213 Resibufogenin and cinobufagin (dpeaa)DE-He213 Ch’an Su (dpeaa)DE-He213 |
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ddc 540 bkl 35.29 misc Gas chromatography–mass spectrometry misc Microwave-assisted silylation misc Resibufogenin and cinobufagin misc Ch’an Su |
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ddc 540 bkl 35.29 misc Gas chromatography–mass spectrometry misc Microwave-assisted silylation misc Resibufogenin and cinobufagin misc Ch’an Su |
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ddc 540 bkl 35.29 misc Gas chromatography–mass spectrometry misc Microwave-assisted silylation misc Resibufogenin and cinobufagin misc Ch’an Su |
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Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
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Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
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Zhu, Xiaoyan |
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749 |
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Zhu, Xiaoyan Meng, Zhiqiang Chen, Zhen Liu, Luming |
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10.1365/s10337-009-0973-7 |
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simultaneous determination of resibufogenin and cinobufagin in chinese medicine ch’an su by gc–ms following microwave-assisted silylation |
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Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
| abstract |
Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. |
| abstractGer |
Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. |
| abstract_unstemmed |
Abstract Resibufogenin and cinobufagin are the major bioactive constituents in the Chinese medicine Ch’an Su. In this paper, a novel, simple and rapid method was developed for the qualitative analysis of the two main compounds, which was based on microwave-assisted silylation followed by gas chromatography–mass spectrometry. The components of resibufogenin and cinobufagin were derivatized with N,O-bis(trimethylsilyl)trifluoroacetamide under microwave irradiation, and the trimethylsilyl derivatives formed were analyzed by GC–MS. The derivatization conditions including microwave power and irradiation time were investigated, and the method validations (linear range, detection limit, precision and recovery) were also studied. The experimental results indicate that microwave-assisted silylation followed by GC–MS analysis is a new method for the determination of resibufogenin and cinobufagin in the Ch’an Su samples. |
| collection_details |
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| container_issue |
7-8 |
| title_short |
Simultaneous Determination of Resibufogenin and Cinobufagin in Chinese Medicine Ch’an Su by GC–MS Following Microwave-Assisted Silylation |
| url |
https://dx.doi.org/10.1365/s10337-009-0973-7 |
| remote_bool |
true |
| author2 |
Meng, Zhiqiang Chen, Zhen Liu, Luming |
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Meng, Zhiqiang Chen, Zhen Liu, Luming |
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| doi_str |
10.1365/s10337-009-0973-7 |
| up_date |
2024-07-04T02:27:46.632Z |
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|
| score |
7.39999 |