Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study
Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 199...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Abdollah, Firas [verfasserIn] Sun, Maxine [verfasserIn] Schmitges, Jan [verfasserIn] Thuret, Rodolphe [verfasserIn] Djahangirian, Orchidee [verfasserIn] Jeldres, Claudio [verfasserIn] Tian, Zhe [verfasserIn] Shariat, Shahrokh F. [verfasserIn] Perrotte, Paul [verfasserIn] Montorsi, Francesco [verfasserIn] Karakiewicz, Pierre I. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2011 |
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| Übergeordnetes Werk: |
Enthalten in: Annals of surgical oncology - Berlin [u.a.] : Springer, 1994, 19(2011), 1 vom: 24. Juni, Seite 309-317 |
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| Übergeordnetes Werk: |
volume:19 ; year:2011 ; number:1 ; day:24 ; month:06 ; pages:309-317 |
| Links: |
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| DOI / URN: |
10.1245/s10434-011-1852-7 |
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| Katalog-ID: |
SPR009946551 |
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| 100 | 1 | |a Abdollah, Firas |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
| 264 | 1 | |c 2011 | |
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| 520 | |a Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. | ||
| 650 | 4 | |a Charlson Comorbidity Index |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Radical Cystectomy |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Urinary Diversion |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Nationwide Inpatient Sample |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Reference Table |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Sun, Maxine |e verfasserin |4 aut | |
| 700 | 1 | |a Schmitges, Jan |e verfasserin |4 aut | |
| 700 | 1 | |a Thuret, Rodolphe |e verfasserin |4 aut | |
| 700 | 1 | |a Djahangirian, Orchidee |e verfasserin |4 aut | |
| 700 | 1 | |a Jeldres, Claudio |e verfasserin |4 aut | |
| 700 | 1 | |a Tian, Zhe |e verfasserin |4 aut | |
| 700 | 1 | |a Shariat, Shahrokh F. |e verfasserin |4 aut | |
| 700 | 1 | |a Perrotte, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Montorsi, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Karakiewicz, Pierre I. |e verfasserin |4 aut | |
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10.1245/s10434-011-1852-7 doi (DE-627)SPR009946551 (SPR)s10434-011-1852-7-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Abdollah, Firas verfasserin aut Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 Sun, Maxine verfasserin aut Schmitges, Jan verfasserin aut Thuret, Rodolphe verfasserin aut Djahangirian, Orchidee verfasserin aut Jeldres, Claudio verfasserin aut Tian, Zhe verfasserin aut Shariat, Shahrokh F. verfasserin aut Perrotte, Paul verfasserin aut Montorsi, Francesco verfasserin aut Karakiewicz, Pierre I. verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 19(2011), 1 vom: 24. Juni, Seite 309-317 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:19 year:2011 number:1 day:24 month:06 pages:309-317 https://dx.doi.org/10.1245/s10434-011-1852-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 19 2011 1 24 06 309-317 |
| spelling |
10.1245/s10434-011-1852-7 doi (DE-627)SPR009946551 (SPR)s10434-011-1852-7-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Abdollah, Firas verfasserin aut Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 Sun, Maxine verfasserin aut Schmitges, Jan verfasserin aut Thuret, Rodolphe verfasserin aut Djahangirian, Orchidee verfasserin aut Jeldres, Claudio verfasserin aut Tian, Zhe verfasserin aut Shariat, Shahrokh F. verfasserin aut Perrotte, Paul verfasserin aut Montorsi, Francesco verfasserin aut Karakiewicz, Pierre I. verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 19(2011), 1 vom: 24. Juni, Seite 309-317 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:19 year:2011 number:1 day:24 month:06 pages:309-317 https://dx.doi.org/10.1245/s10434-011-1852-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 19 2011 1 24 06 309-317 |
| allfields_unstemmed |
10.1245/s10434-011-1852-7 doi (DE-627)SPR009946551 (SPR)s10434-011-1852-7-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Abdollah, Firas verfasserin aut Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 Sun, Maxine verfasserin aut Schmitges, Jan verfasserin aut Thuret, Rodolphe verfasserin aut Djahangirian, Orchidee verfasserin aut Jeldres, Claudio verfasserin aut Tian, Zhe verfasserin aut Shariat, Shahrokh F. verfasserin aut Perrotte, Paul verfasserin aut Montorsi, Francesco verfasserin aut Karakiewicz, Pierre I. verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 19(2011), 1 vom: 24. Juni, Seite 309-317 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:19 year:2011 number:1 day:24 month:06 pages:309-317 https://dx.doi.org/10.1245/s10434-011-1852-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 19 2011 1 24 06 309-317 |
| allfieldsGer |
10.1245/s10434-011-1852-7 doi (DE-627)SPR009946551 (SPR)s10434-011-1852-7-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Abdollah, Firas verfasserin aut Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 Sun, Maxine verfasserin aut Schmitges, Jan verfasserin aut Thuret, Rodolphe verfasserin aut Djahangirian, Orchidee verfasserin aut Jeldres, Claudio verfasserin aut Tian, Zhe verfasserin aut Shariat, Shahrokh F. verfasserin aut Perrotte, Paul verfasserin aut Montorsi, Francesco verfasserin aut Karakiewicz, Pierre I. verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 19(2011), 1 vom: 24. Juni, Seite 309-317 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:19 year:2011 number:1 day:24 month:06 pages:309-317 https://dx.doi.org/10.1245/s10434-011-1852-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 19 2011 1 24 06 309-317 |
| allfieldsSound |
10.1245/s10434-011-1852-7 doi (DE-627)SPR009946551 (SPR)s10434-011-1852-7-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Abdollah, Firas verfasserin aut Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 Sun, Maxine verfasserin aut Schmitges, Jan verfasserin aut Thuret, Rodolphe verfasserin aut Djahangirian, Orchidee verfasserin aut Jeldres, Claudio verfasserin aut Tian, Zhe verfasserin aut Shariat, Shahrokh F. verfasserin aut Perrotte, Paul verfasserin aut Montorsi, Francesco verfasserin aut Karakiewicz, Pierre I. verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 19(2011), 1 vom: 24. Juni, Seite 309-317 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:19 year:2011 number:1 day:24 month:06 pages:309-317 https://dx.doi.org/10.1245/s10434-011-1852-7 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 19 2011 1 24 06 309-317 |
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Enthalten in Annals of surgical oncology 19(2011), 1 vom: 24. Juni, Seite 309-317 volume:19 year:2011 number:1 day:24 month:06 pages:309-317 |
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Charlson Comorbidity Index Radical Cystectomy Urinary Diversion Nationwide Inpatient Sample Reference Table |
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Abdollah, Firas @@aut@@ Sun, Maxine @@aut@@ Schmitges, Jan @@aut@@ Thuret, Rodolphe @@aut@@ Djahangirian, Orchidee @@aut@@ Jeldres, Claudio @@aut@@ Tian, Zhe @@aut@@ Shariat, Shahrokh F. @@aut@@ Perrotte, Paul @@aut@@ Montorsi, Francesco @@aut@@ Karakiewicz, Pierre I. @@aut@@ |
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|
| author |
Abdollah, Firas |
| spellingShingle |
Abdollah, Firas ddc 610 bkl 44.81 bkl 44.65 misc Charlson Comorbidity Index misc Radical Cystectomy misc Urinary Diversion misc Nationwide Inpatient Sample misc Reference Table Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
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1534-4681 |
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610 ASE 44.81 bkl 44.65 bkl Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study Charlson Comorbidity Index (dpeaa)DE-He213 Radical Cystectomy (dpeaa)DE-He213 Urinary Diversion (dpeaa)DE-He213 Nationwide Inpatient Sample (dpeaa)DE-He213 Reference Table (dpeaa)DE-He213 |
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ddc 610 bkl 44.81 bkl 44.65 misc Charlson Comorbidity Index misc Radical Cystectomy misc Urinary Diversion misc Nationwide Inpatient Sample misc Reference Table |
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ddc 610 bkl 44.81 bkl 44.65 misc Charlson Comorbidity Index misc Radical Cystectomy misc Urinary Diversion misc Nationwide Inpatient Sample misc Reference Table |
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ddc 610 bkl 44.81 bkl 44.65 misc Charlson Comorbidity Index misc Radical Cystectomy misc Urinary Diversion misc Nationwide Inpatient Sample misc Reference Table |
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Annals of surgical oncology |
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Annals of surgical oncology |
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Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
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(DE-627)SPR009946551 (SPR)s10434-011-1852-7-e |
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Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
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Abdollah, Firas |
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Annals of surgical oncology |
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Annals of surgical oncology |
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eng |
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600 - Technology |
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2011 |
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Abdollah, Firas Sun, Maxine Schmitges, Jan Thuret, Rodolphe Djahangirian, Orchidee Jeldres, Claudio Tian, Zhe Shariat, Shahrokh F. Perrotte, Paul Montorsi, Francesco Karakiewicz, Pierre I. |
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610 ASE 44.81 bkl 44.65 bkl |
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Elektronische Aufsätze |
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Abdollah, Firas |
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10.1245/s10434-011-1852-7 |
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610 |
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verfasserin |
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development and validation of a reference table for prediction of postoperative mortality rate in patients treated with radical cystectomy: a population-based study |
| title_auth |
Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
| abstract |
Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. |
| abstractGer |
Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. |
| abstract_unstemmed |
Purpose The existing literature suggests that the postoperative mortality (POM) rate in radical cystectomy (RC) patients does not exceed 3%. We sought to develop and externally validate a reference table that quantifies POM after RC. Methods We identified 12,274 patients treated with RC, between 1998 and 2007, within the Nationwide Inpatient Sample database. A total of 6188 (50.4%) randomly selected patients was used as the development cohort. Logistic regression analysis for prediction of POM adjusted for: age, sex, race, Charlson comorbidity index (CCI), urinary diversion type, year of surgery, annual hospital caseload, location/teaching status of hospital, region and bed size of hospital. The reference table was developed by using stepwise variable removal to identify the most accurate and parsimonious model. The model was externally validated in 6086 (49.6%) patients. Results POM occurred in 2.4% of patients. POM proportion increased with increasing age (≤59: 0.6% vs. 60–69: 1.6% vs. 70–79: 3.1% vs. ≥80: 4.6%, P < 0.001), and higher CCI (CCI 0: 1.7% vs. CCI 1: 3.0% vs. CCI 2: 4.2% vs. CCI 3: 4.3% vs. CCI ≥ 4: 12.1%, P < 0.001). In multivariable analyses, only age and CCI remained as independent predictors of POM, after stepwise variable removal. The discrimination accuracy of the reference table in predicting POM was 70%. Conclusions Age and CCI represent the foremost determinants of POM after RC. The developed reference table is capable of predicting POM after RC, in an individualized fashion. The accuracy of the model is good (70%), and it is highly generalizable. |
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1 |
| title_short |
Development and Validation of a Reference Table for Prediction of Postoperative Mortality Rate in Patients Treated with Radical Cystectomy: A Population-based Study |
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https://dx.doi.org/10.1245/s10434-011-1852-7 |
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Sun, Maxine Schmitges, Jan Thuret, Rodolphe Djahangirian, Orchidee Jeldres, Claudio Tian, Zhe Shariat, Shahrokh F. Perrotte, Paul Montorsi, Francesco Karakiewicz, Pierre I. |
| author2Str |
Sun, Maxine Schmitges, Jan Thuret, Rodolphe Djahangirian, Orchidee Jeldres, Claudio Tian, Zhe Shariat, Shahrokh F. Perrotte, Paul Montorsi, Francesco Karakiewicz, Pierre I. |
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10.1245/s10434-011-1852-7 |
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2024-07-04T03:37:36.045Z |
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1803618097345593344 |
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| score |
7.4013615 |