The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases
Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and wi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Okumura, Hiroshi [verfasserIn] Uchikado, Yasuto [verfasserIn] Omoto, Itaru [verfasserIn] Kita, Yoshiaki [verfasserIn] Sasaki, Ken [verfasserIn] Arigami, Takaaki [verfasserIn] Uenosono, Yoshikazu [verfasserIn] Matsushita, Daisuke [verfasserIn] Hiraki, Yoshiyuki [verfasserIn] Owaki, Tetsuhiro [verfasserIn] Ishigami, Sumiya [verfasserIn] Natsugoe, Shoji [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2014 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Annals of surgical oncology - Berlin [u.a.] : Springer, 1994, 21(2014), 9 vom: 14. Apr., Seite 2845-2849 |
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| Übergeordnetes Werk: |
volume:21 ; year:2014 ; number:9 ; day:14 ; month:04 ; pages:2845-2849 |
| Links: |
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| DOI / URN: |
10.1245/s10434-014-3688-4 |
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| Katalog-ID: |
SPR009965807 |
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| 100 | 1 | |a Okumura, Hiroshi |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
| 264 | 1 | |c 2014 | |
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| 520 | |a Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. | ||
| 650 | 4 | |a Esophageal Cancer |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Histological Response |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Organ Metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Pathological Lymph Node Metastasis |7 (dpeaa)DE-He213 | |
| 650 | 4 | |a Cervical Esophagogastric Anastomosis |7 (dpeaa)DE-He213 | |
| 700 | 1 | |a Uchikado, Yasuto |e verfasserin |4 aut | |
| 700 | 1 | |a Omoto, Itaru |e verfasserin |4 aut | |
| 700 | 1 | |a Kita, Yoshiaki |e verfasserin |4 aut | |
| 700 | 1 | |a Sasaki, Ken |e verfasserin |4 aut | |
| 700 | 1 | |a Arigami, Takaaki |e verfasserin |4 aut | |
| 700 | 1 | |a Uenosono, Yoshikazu |e verfasserin |4 aut | |
| 700 | 1 | |a Matsushita, Daisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Hiraki, Yoshiyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Owaki, Tetsuhiro |e verfasserin |4 aut | |
| 700 | 1 | |a Ishigami, Sumiya |e verfasserin |4 aut | |
| 700 | 1 | |a Natsugoe, Shoji |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Annals of surgical oncology |d Berlin [u.a.] : Springer, 1994 |g 21(2014), 9 vom: 14. Apr., Seite 2845-2849 |w (DE-627)343969947 |w (DE-600)2074021-9 |x 1534-4681 |7 nnns |
| 773 | 1 | 8 | |g volume:21 |g year:2014 |g number:9 |g day:14 |g month:04 |g pages:2845-2849 |
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| allfields |
10.1245/s10434-014-3688-4 doi (DE-627)SPR009965807 (SPR)s10434-014-3688-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Okumura, Hiroshi verfasserin aut The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 Uchikado, Yasuto verfasserin aut Omoto, Itaru verfasserin aut Kita, Yoshiaki verfasserin aut Sasaki, Ken verfasserin aut Arigami, Takaaki verfasserin aut Uenosono, Yoshikazu verfasserin aut Matsushita, Daisuke verfasserin aut Hiraki, Yoshiyuki verfasserin aut Owaki, Tetsuhiro verfasserin aut Ishigami, Sumiya verfasserin aut Natsugoe, Shoji verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 21(2014), 9 vom: 14. Apr., Seite 2845-2849 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 https://dx.doi.org/10.1245/s10434-014-3688-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 21 2014 9 14 04 2845-2849 |
| spelling |
10.1245/s10434-014-3688-4 doi (DE-627)SPR009965807 (SPR)s10434-014-3688-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Okumura, Hiroshi verfasserin aut The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 Uchikado, Yasuto verfasserin aut Omoto, Itaru verfasserin aut Kita, Yoshiaki verfasserin aut Sasaki, Ken verfasserin aut Arigami, Takaaki verfasserin aut Uenosono, Yoshikazu verfasserin aut Matsushita, Daisuke verfasserin aut Hiraki, Yoshiyuki verfasserin aut Owaki, Tetsuhiro verfasserin aut Ishigami, Sumiya verfasserin aut Natsugoe, Shoji verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 21(2014), 9 vom: 14. Apr., Seite 2845-2849 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 https://dx.doi.org/10.1245/s10434-014-3688-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 21 2014 9 14 04 2845-2849 |
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10.1245/s10434-014-3688-4 doi (DE-627)SPR009965807 (SPR)s10434-014-3688-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Okumura, Hiroshi verfasserin aut The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 Uchikado, Yasuto verfasserin aut Omoto, Itaru verfasserin aut Kita, Yoshiaki verfasserin aut Sasaki, Ken verfasserin aut Arigami, Takaaki verfasserin aut Uenosono, Yoshikazu verfasserin aut Matsushita, Daisuke verfasserin aut Hiraki, Yoshiyuki verfasserin aut Owaki, Tetsuhiro verfasserin aut Ishigami, Sumiya verfasserin aut Natsugoe, Shoji verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 21(2014), 9 vom: 14. Apr., Seite 2845-2849 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 https://dx.doi.org/10.1245/s10434-014-3688-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 21 2014 9 14 04 2845-2849 |
| allfieldsGer |
10.1245/s10434-014-3688-4 doi (DE-627)SPR009965807 (SPR)s10434-014-3688-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Okumura, Hiroshi verfasserin aut The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 Uchikado, Yasuto verfasserin aut Omoto, Itaru verfasserin aut Kita, Yoshiaki verfasserin aut Sasaki, Ken verfasserin aut Arigami, Takaaki verfasserin aut Uenosono, Yoshikazu verfasserin aut Matsushita, Daisuke verfasserin aut Hiraki, Yoshiyuki verfasserin aut Owaki, Tetsuhiro verfasserin aut Ishigami, Sumiya verfasserin aut Natsugoe, Shoji verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 21(2014), 9 vom: 14. Apr., Seite 2845-2849 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 https://dx.doi.org/10.1245/s10434-014-3688-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 21 2014 9 14 04 2845-2849 |
| allfieldsSound |
10.1245/s10434-014-3688-4 doi (DE-627)SPR009965807 (SPR)s10434-014-3688-4-e DE-627 ger DE-627 rakwb eng 610 ASE 44.81 bkl 44.65 bkl Okumura, Hiroshi verfasserin aut The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 Uchikado, Yasuto verfasserin aut Omoto, Itaru verfasserin aut Kita, Yoshiaki verfasserin aut Sasaki, Ken verfasserin aut Arigami, Takaaki verfasserin aut Uenosono, Yoshikazu verfasserin aut Matsushita, Daisuke verfasserin aut Hiraki, Yoshiyuki verfasserin aut Owaki, Tetsuhiro verfasserin aut Ishigami, Sumiya verfasserin aut Natsugoe, Shoji verfasserin aut Enthalten in Annals of surgical oncology Berlin [u.a.] : Springer, 1994 21(2014), 9 vom: 14. Apr., Seite 2845-2849 (DE-627)343969947 (DE-600)2074021-9 1534-4681 nnns volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 https://dx.doi.org/10.1245/s10434-014-3688-4 lizenzpflichtig Volltext GBV_USEFLAG_A SYSFLAG_A GBV_SPRINGER SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_702 GBV_ILN_711 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2107 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2446 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4328 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.81 ASE 44.65 ASE AR 21 2014 9 14 04 2845-2849 |
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Enthalten in Annals of surgical oncology 21(2014), 9 vom: 14. Apr., Seite 2845-2849 volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 |
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Enthalten in Annals of surgical oncology 21(2014), 9 vom: 14. Apr., Seite 2845-2849 volume:21 year:2014 number:9 day:14 month:04 pages:2845-2849 |
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Esophageal Cancer Histological Response Organ Metastasis Pathological Lymph Node Metastasis Cervical Esophagogastric Anastomosis |
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Annals of surgical oncology |
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Okumura, Hiroshi @@aut@@ Uchikado, Yasuto @@aut@@ Omoto, Itaru @@aut@@ Kita, Yoshiaki @@aut@@ Sasaki, Ken @@aut@@ Arigami, Takaaki @@aut@@ Uenosono, Yoshikazu @@aut@@ Matsushita, Daisuke @@aut@@ Hiraki, Yoshiyuki @@aut@@ Owaki, Tetsuhiro @@aut@@ Ishigami, Sumiya @@aut@@ Natsugoe, Shoji @@aut@@ |
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2014-04-14T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">SPR009965807</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230519224417.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">201005s2014 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1245/s10434-014-3688-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)SPR009965807</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SPR)s10434-014-3688-4-e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">ASE</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.81</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.65</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Okumura, Hiroshi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). 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|
| author |
Okumura, Hiroshi |
| spellingShingle |
Okumura, Hiroshi ddc 610 bkl 44.81 bkl 44.65 misc Esophageal Cancer misc Histological Response misc Organ Metastasis misc Pathological Lymph Node Metastasis misc Cervical Esophagogastric Anastomosis The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
| authorStr |
Okumura, Hiroshi |
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@@773@@(DE-627)343969947 |
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electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
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aut aut aut aut aut aut aut aut aut aut aut aut |
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springer |
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true |
| illustrated |
Not Illustrated |
| issn |
1534-4681 |
| topic_title |
610 ASE 44.81 bkl 44.65 bkl The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases Esophageal Cancer (dpeaa)DE-He213 Histological Response (dpeaa)DE-He213 Organ Metastasis (dpeaa)DE-He213 Pathological Lymph Node Metastasis (dpeaa)DE-He213 Cervical Esophagogastric Anastomosis (dpeaa)DE-He213 |
| topic |
ddc 610 bkl 44.81 bkl 44.65 misc Esophageal Cancer misc Histological Response misc Organ Metastasis misc Pathological Lymph Node Metastasis misc Cervical Esophagogastric Anastomosis |
| topic_unstemmed |
ddc 610 bkl 44.81 bkl 44.65 misc Esophageal Cancer misc Histological Response misc Organ Metastasis misc Pathological Lymph Node Metastasis misc Cervical Esophagogastric Anastomosis |
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ddc 610 bkl 44.81 bkl 44.65 misc Esophageal Cancer misc Histological Response misc Organ Metastasis misc Pathological Lymph Node Metastasis misc Cervical Esophagogastric Anastomosis |
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The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
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The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
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Okumura, Hiroshi |
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Okumura, Hiroshi Uchikado, Yasuto Omoto, Itaru Kita, Yoshiaki Sasaki, Ken Arigami, Takaaki Uenosono, Yoshikazu Matsushita, Daisuke Hiraki, Yoshiyuki Owaki, Tetsuhiro Ishigami, Sumiya Natsugoe, Shoji |
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Okumura, Hiroshi |
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usefulness of neoadjuvant chemoradiation therapy for locally advanced esophageal cancer with multiple lymph-node metastases |
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The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
| abstract |
Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. |
| abstractGer |
Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. |
| abstract_unstemmed |
Background The prognosis of patients with esophageal squamous-cell cancer (ESCC) and multiple lymph-node metastases is quite poor. We examined whether neoadjuvant chemoradiation therapy (CRT) has a beneficial effect in such patients. Methods A total of 50 consecutive patients with T3–4 tumors and without organ metastases were prospectively enrolled. Of those patients, 20, who had four or more nodal metastases, underwent neoadjuvant CRT (CRT group), and the remaining 30 patients, who had three or fewer nodal metastases, underwent surgery alone (surgery group). CRT consisted of 5-fluorouracil plus cisplatin and 40 Gy of radiation. The groups’ clinical outcomes were compared. Results Surgery was performed in 48 patients: all enrolled patients except for 2 who had organ metastasis after CRT. In the CRT group, the number of patients with pathological complete response was observed in 8 patients (44 %), mean nodal metastases number was changed from 8.2 to 2.6 and 9 patients had pN0. The 3-year survival rate was 76 % in the CRT group (4 patients relapsed) and 68 % in the surgery group (8 patients relapsed), which is not a statistically significant difference (P = 0.61). Conclusions Neoadjuvant CRT is beneficial for locally advanced ESCC with four or more lymph-node metastases. |
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The Usefulness of Neoadjuvant Chemoradiation Therapy for Locally Advanced Esophageal Cancer with Multiple Lymph-Node Metastases |
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Uchikado, Yasuto Omoto, Itaru Kita, Yoshiaki Sasaki, Ken Arigami, Takaaki Uenosono, Yoshikazu Matsushita, Daisuke Hiraki, Yoshiyuki Owaki, Tetsuhiro Ishigami, Sumiya Natsugoe, Shoji |
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| score |
7.399477 |